Kukulo liphi izinga likashukela imijovo ye-insulin ebekiwe

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I-glucose yi-carbohydrate kanye nomthombo wamandla womzimba ongena kuwo ngokudla. Isiza ukumunca lo muthi futhi isheshise imetabolism yeselula ye-peptide hormone insulin. Uma ngesizathu esithile kungenzekwanga ngamanani afanele (noma akhiqizwanga nhlobo), khona-ke okuqukethwe ushukela osegazini kukhuphuka kakhulu, okugcwele ukuthuthukiswa kwesifo sikashukela mellitus.

Abathinteka kakhulu kule ndlela yokusebenza ngabantu abanokuphambuka kwifa. Kufanele bahlolwe ngokuhlelekile futhi bathole kusengaphambili ukuthi iluphi ushukela wegazi olungiselelwe i-insulin. Isetshenziswa ikakhulukazi ohlotsheni lokuqala lwesifo, kodwa futhi ngesimo lwayo lwesibili, ukwelashwa kwe-insulin kusetshenziswa kaningi.

Isidingo sokwelashwa

Ngohlobo lwesibili sikashukela, ukukhiqizwa kwe-insulin kuncishiswa kakhulu, bese izicubu ziba semgudwini waleli hormone, elihlanganisa inqubo ye-metabolic. Ukulungisa ukwephulwa, ama-pancreas kufanele asebenze kumodi ethuthukisiwe. Umthwalo ohlala ukhula kancane kancane emzimbeni, ikakhulukazi uma ukudla okuphephile kungabhekwa.

Izinkinga ze-Endocrine zivusa:

  • ukukhuluphala
  • kwehlise ukungatheleleki;
  • ukusebenza ngokweqile;
  • ukuphazamiseka kwe-hormonal;
  • izinguquko ezihlobene nobudala;
  • izinqubo zesimila kumanyikwe.

Iziguli eziningi zesaba ukushintshela kumijovo yansuku zonke ye-insulin yokufakelwa futhi zizama ukubambezela lesi sikhathi isikhathi eside ngangokunokwenzeka. Eqinisweni, umuthi ngeke usize ukugcina umzimba usesimweni esihle kuphela, kepha futhi uvikele ukuthuthukiswa kwezifo ezihlangana nazo.

Isifo sikashukela nokucindezela kuzoba yinto yesikhathi esedlule

  • Ukwehlela ushukela -95%
  • Ukuqedwa kwe-vein thrombosis - 70%
  • Ukuqedwa kokushaya kwenhliziyo okuqinile -90%
  • Ukuqeda umfutho wegazi ophakeme - 92%
  • Ukwanda kwamandla ngesikhathi sosuku, ngcono ukulala ebusuku -97%

Izici Zokuya

Amaseli weBeta akhiqiza i-insulin ngokugcwele, enxephezela isifo sikashukela. Odokotela abasibheki isiguli ngokushesha ukuthi sinesimo "esincike ku-insulin", bezama ukubuyisa isitho ngezinye izindlela ekuqaleni kokwelashwa. Lapho umphumela oyifunayo ungatholakali, izindlela ezisetshenzisiwe ziyeka ukusebenza, isiguli sinqunywe i-insulin.

Kubalulekile! Ukuze ungaphuthelwa isikhathi esiyigugu futhi ulawule lesi sifo, isiguli kufanele sihlolwe njalo igazi izinkomba zoshukela.

Izizathu ze-Insulin

Kunezizathu eziningana lapho kungeniswa kwe-hormone yokufakelwa kudingekile ukuze isimo saso sibe sesijwayelekile:

  • okuqukethwe ushukela omningi, okungaphezulu kuka-9 mmol / l;
  • ukubambezeleka okuhlala isikhathi eside. Izinga likashukela elikhuphukile livame ukunganakwa yiziguli, ngoba zivame ukuthi zibonisa izimpawu zokugula kwezinye izifo futhi zingathintani nodokotela onguchwepheshe - mayelana nesifo sikashukela esibolile;
  • umfutho wegazi ophakeme, ukuncipha okubonakalayo, ukwehla njalo kwe-cephalalgia, ukuncipha kwemithambo yegazi;
  • ukwephulwa kwamanyikwe, ikakhulukazi okwenzeka ngemuva kweminyaka engama-45;
  • ama-pathologies we-vascular ezinzima;
  • izimo ezimbi kakhulu ngokuthuthukiswa kwezifo ezinzima, ngokwesibonelo, umkhuhlane, uma kunesidingo, ukungenelela okuphuthumayo kokuhlinzwa. Ukwelashwa kwe-insulin kuvumela umzimba ukuba ubhekane nesimo esibucayi;
  • ukuphuza izidakamizwa ezingasebenzi, noma ukuzisebenzisa ngokweqile.

Kulokhu, i-insulin yokufakelwa inqunywa ngokushesha, futhi isilinganiso somthamo sinqunywa ngokusekelwe ekubaleni kwegazi.

Ukuthuthukiswa kwesifo sikashukela

I-pancreas enempilo isebenza kahle, ikhiqiza inani elifanelekile le-insulin. IGlucose etholwe ngokudla iphukile emgodini wokugaya ukudla bese ingena egazini. Ngemuva kwalokho, ukungena kumaseli, kuwanikeza amandla. Ukuze le nqubo iqhubeke ngaphandle kokuphazamiseka, kudingeka ukuthi kudedelwe insulin nokulimala kwezicubu ezindaweni zokungena kwamaprotheni kulolwelwesi lweseli. Uma ukuzwela kwama-receptors kukhubazekile futhi kungekho ukuthambeka, khona-ke i-glucose ayikwazi ukungena esitokisini. Lesi simo sibonwa ngohlobo 2 sikashukela.

Iziguli zinesifiso sokuthi yiziphi izinkomba okufanele ziqale ukwelashwa kwe-insulin. Kakade i-6 mmol / L esegazini ikhombisa ukuthi umsoco udinga ukulungiswa. Uma izinkomba zifinyelela ku-9, lapho-ke kufanele uhlole umzimba ukuthi ukhona we-glucose ubuthi - funda ukuthi yini ukwephula ukubekezelelwa kwe-glucose.

Leli gama lisho ukuthi izinqubo ezingenakuphikiswa ziqala ukushabalalisa amaseli we-beta wamanyikwe. Ama-glycosylating agents aphazamisa ukukhiqizwa kwama-hormone futhi aqala ukukhiqiza ngokuzimela i-insulin. Uma izinsolo zikachwepheshe ziqinisekisiwe, kusetshenziswa izindlela ezahlukahlukene zokubamba. Ukuthi imiphumela yezindlela zokwelapha izohlala isikhathi eside kangakanani kuya ngokuthi ukugcinwa kwemithetho yeziguli nokwelashwa okusebenzayo kukadokotela.

Kwezinye izimo, ukuphathwa okufishane kwesidakamizwa kwanele ukubuyisela ukuvela kwe-insulin ejwayelekile. Kepha imvamisa kufanele iphathwe nsuku zonke.

Ukusetshenziswa kwe-insulin

Isiguli kufanele sibheke ukuthi uma kunenkomba yokuqokwa kwe-insulin, ukwenqaba ukwelashwa kuyingozi empilweni nokuphila. Umzimba onenkinga yesifo sikashukela ubhujiswa ngokushesha okukhulu. Kulokhu, ukubuyela ezibhebheni kungenzeka ngemuva kwendlela ethile yokwelashwa (lapho amangqamuzana e-beta aphilayo esahlala emzimbeni).

I-insulin ilawulwa ngesilinganiso esenziwe kahle nomthamo. Ubuchwepheshe besimanje bezemithi benza inqubo yokusebenzisa umuthi ungabi buhlungu ngokuphelele. Kukhona ama-syringes-amapeni nosrringes anezinaliti ezincane, ngenxa yokuthi umuntu angenza umjovo ngenduduzo ephezulu.

Lapho kunikezwe i-insulin, ochwepheshe kufanele bakhombise izindawo ezisemzimbeni lapho umuthi uphathwa kahle khona: isisu, izitho ezingenhla nezingaphansi, amabhuzu. Kulezi zindawo zomzimba, isiguli sizokwazi ukwenza umjovo ngaphandle kokufuna usizo lwangaphandle - indlela yokujova i-insulin.

Kubalulekile! Uma i-glycemia yaqoshwa ngesikhathi sokunikela kwegazi okusheshayo, futhi izinkomba zedlula i-7 mmol / l lapho kuthatha amaphilisi anciphisa ushukela nangokunamathela okuqinile ekudleni, khona-ke uchwepheshe unikeza ukungeniswa kwehomoni yokufakelwa ukuze kugcinwe ukusebenza okujwayelekile komzimba.

Iqiniso nezinganekwane

Ngendlela yesifo sikashukela esincike ku-insulin, umuntu udinga ukwelashwa kwe-insulin njalo. Kepha ngisho nohlobo lwesibili, ukuphathwa kwehomoni kunqunywa kaningi. Wonke umuntu onesifo sikashukela ubhekene neqiniso lokuthi ukwelashwa kuqala ukuba kuncike emijozweni. Ukwesaba inqubo, ukwesaba okuzwakala kubangani, injabulo kanye nokukhathazeka kungayilimaza impilo yakho. Udokotela kumele asekele isiguli, simchazele ukuthi lesi yisigaba esidingekayo sokwelashwa lapho amakhulu ezinkulungwane zabantu ehamba khona.

I-insulin yokwenziwa inqunyelwe kuphela kumanani abucayi kashukela wegazi, lapho i-pancreas iyeka ukusebenza ngisho nangemodi encane. Ngosizo lwayo ukuthi ama-carbohydrate angena kumaseli, futhi ngaphandle kwalezi zinto umuntu ngeke akwazi ukuba khona. Lapho amaseli we-beta efa, kuyadingeka ukufaka umjovo umuthi. Gwema imijovo ngeke isebenze. Ngaphandle kwalokho, ngokuqongelela ubuthi, unhlangothi, ukuhlaselwa yisifo senhliziyo, kanye nokuphefumula kwe-cerebral ngethonya elibulalayo kungakhula. Ukulandela yonke imithetho yokwelashwa kuzosiza ukugcina isimo sempilo somuntu esivamile futhi sandise impilo yakhe iminyaka eminingi.

Umthamo

Imvamisa, abantu abathatha i-insulin bahlushwa imiphumela yesifo sikashukela. Ahlotshaniswa hhayi nomuthi, kodwa nemininingwane yokugula, lapho amazinga kashukela angenyuka kakhulu. Lokhu kwesinye isikhathi kubangelwa ukwehliswa okungazi emthanjeni obekwe udokotela, njengoba ezinye iziguli zikholelwa ukuthi ziyelulekwa ukuthi zifake insulin kakhulu. Ngenxa yalokhu, umuntu onesifo sikashukela ubhekene nama-pathologies angathi sína:

  • izilonda ezinyaweni, okuholela kwezicubu ze-necrosis (ukufa), i-gangrene kanye nokuqunjelwa;
  • ukungaboni kahle okubukhali, ukungaboni - retinopathy yesifo sikashukela;
  • ukwehluleka kwesibindi nezinso - i-nephropathy yesifo sikashukela;
  • ama-pathologies we-vascular, atherossteosis, unhlangothi, ukushaya kwenhliziyo;
  • ukuthuthukiswa kwe-oncopathologies.

Ukuze uvimbele noma uvimbele ukuthuthukiswa kwalezi zifo, kufanele ufake i-insulin emihlanganweni enqunywe uchwepheshe onolwazi futhi ungazibandakanyi ekuzivumelaniseni kokuziqanjwa komthamo.

Ekuqaleni kokufakwa kwehomoni yokufakelwa, kunconyelwa ukwenza imijovo eyi-1-2 ngosuku. Ngokuzayo, umthamo uguqulwa yi-endocrinologist:

  • unaka isidingo somuthi ebusuku;
  • umthamo wokuqala usungulwa bese ulungiswa;
  • umthamo we-insulin yasekuseni ubalwa. Kulokhu, isiguli kuzodingeka seqe ukudla;
  • ngesidingo se-insulin esisheshayo, onesifo sikashukela kufanele anqume ngaphambi kokuthi ayethulwe isidlo esikhulu esingakanani;
  • lapho kunqunywa imithamo, kubalulekile ukuba unake ukugcwala ushukela ezinsukwini ezedlule;
  • isiguli siyelulekwa ukuthi sithole isikhathi esingakanani ngaphambi kokudla i-hormone yokwenziwa.

Ngokwengeziwe kusihloko: Ungayibala kanjani kahle imithamo ye-insulin

Imiphumela yokwelashwa kwe-insulin

Imijovo yansuku zonke ihlala ibangela ukwesaba okungokwemvelo kubantu, okuholela ekwandiseni ubungozi bokusabela okungekuhle. I-insulin ine-drawback eyodwa. Ngokungasebenzi ngokomzimba, kuholela kokugcwala kanye nesethi yamaphawundi angeziwe. Kepha ochwepheshe bayaqiniseka ukuthi lokhu kungabhekanwa nakho.

Isifo sikashukela sidinga indlela yokuphila esebenzayo nenempilo nokusebenzisa ukudla okuyimpoqo. Noma ukubala kwegazi kubuyela kokujwayelekile, awudingi ukukhohlwa ukuthambekela kokuthola ukugula, ukuphazamisa ukudla, ukulala, ukuphumula.

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