Kungani i-hypoglycemia yenzeka ezinganeni ezisanda kuzalwa futhi iphathwa kanjani

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I-Hypoglycemia ezinganeni ezisanda kuzalwa yinto eyenzeka lapho izinga likashukela egazini lazo liwela ngaphansi kwe-2 mmol / L ngaphakathi kwamahora angama-2-3 ngemuva kokuzalwa. Izibalo zikhombisa ukuthi lesi simo sikhula ku-3% yazo zonke izingane. Ukusungulwa okwandisiwe, isisindo esiphansi, i-asphyxia ye-perinatal kungavusa i-hypoglycemia ezinganeni.

Ukuze udokotela akwazi ukuthola lolu hlobo lokuxilonga, wenza ukuhlolwa koshukela kosana olusanda kuzalwa. Lesi simo simiswa nje - ukwelashwa kuqukethe ukuphathwa kwe-glucose kwe-intravenous. I-Hypoglycemia ingenye yezimbangela ezivame kakhulu zokufa phakathi kwezingane ezisanda kuzalwa.

Ukuhlukaniswa

I-Hypoglycemia ezinganeni ezisanda kuzalwa zezinhlobo ezimbili: ezingapheli nezesikhashana. Uhlobo lwesikhashana kwenzeka ngokungafani nesizinda sokuvuthwa kwe-pancreatic, okungeke kukhiqize ama-enzyme anele, noma ukunikezwa okuphansi komhlaba. Konke lokhu akuvumeli umzimba ukuthi uqongelele inani elidingekayo le-glycogen. Ezimweni ezingavamile, i-hypoglycemia eqhubekayo itholakala ezinganeni ezisanda kuzalwa. Lolu hlobo lesion lubonakala ngokuncika kwe-insulin, kwenzeka ngenxa yokwephulwa komkhiqizo wama-hormone aphikisayo. Ezimweni ezingavamile, i-lesion enjalo ibangelwa ukuphazamiseka kwe-metabolic.

Ukuthuthuka kwangaphambi kwesikhathi kwe-hypoglycemia kungabangelwa ukukhula kuqala ezinganeni ezinesisindo esibuthakathaka noma ngokuntuleka kwe-placental. I-asphyxia ye-Intranatal nayo ingaholela emiphumeleni enjalo. Ukuntuleka komoya-mpilo kubhubhisa izitolo ze-glycogen emzimbeni, ngakho-ke i-hypoglycemia ingakhula kulezi zingane ezinsukwini ezimbalwa zokuphila. Ukuphumula okukhulu phakathi kokuphakelayo nakho kungaholela kulokhu.

Kubaluleke kakhulu ukuthi kuqinisekiswe ukulethwa okushibhile kwe-glucose emzimbeni ukuze kuvikeleke ukuthuthukiswa kwe-hypoglycemia.

I-hypoglycemia yesikhashana ivame ukwenzeka ezinganeni ezisanda kuzalwa ezinomama onesifo sikashukela. Futhi, le nto iba ngokuqhathanisa nesizinda sokuxineka ngokomzimba. Ezimweni ezingavamile, lokhu kudalwa kwesifo kubangelwa yisifo se-autoimmune lapho umzimba udinga khona insulin enkulu. I-Hyperplasia yamaseli kumanyikwe, i-Beckwith-Wiedemann syndrome ingavusa ukuthuthukiswa kwe-pathology enjalo.

Izizathu

I-Hypoglycemia ezinganeni ezisanda kuzalwa zingakhula ngokushesha ngemuva kokuzalwa kuze kufike ezinsukwini ezingama-5 zokukhula kwayo. Esikhathini esiningi samacala, ukwephulwa okunjalo kubangelwa ukukhula okunganele kwe-intrauterine noma ukubambezeleka ekwakhekeni kwezitho zangaphakathi.

Futhi, ukuphazamiseka kwe-metabolic kungaholela ku-hypoglycemia. Ingozi enkulu kakhulu indlela ephikelelayo yokuphambuka okunjalo. Uthi i-hypoglycemia idalwa yi-patgenital pathologies. Lesi simo sidinga ukuqashwa njalo nokulungiswa njalo kwezokwelapha.

Nge-hypoglycemia yesikhashana, ukwehla kokuhlushwa ushukela kuyancipha ngesikhathi esisodwa, ngemuva kokukhululeka okusheshayo, ukuhlasela akudingi ukwelashwa okuhlala isikhathi eside. Kodwa-ke, izinhlobo ezimbili zokuphambuka okukodwa zidinga ukuphendula okusuka kudokotela. Noma ukubambezeleka okuncane kungadala ukuphambuka okukhulu ekusebenzeni kohlelo lwezinzwa, okuthi esikhathini esizayo kungaholele ekuphambukeni emsebenzini wezitho zangaphakathi.

Ezinye zezimbangela ezivame kakhulu ze-hypoglycemia ezinganeni ezisanda kuzalwa yilezi:

  • Ukwelashwa kwe-insulin ekhulelwe ngokuthatha isikhathi eside;
  • Isifo sikashukela soMama
  • Ukudla okukhulu kwe-glucose ephezulu ngaphambi nje kokuzalwa;
  • I-Hypotrophy ye-fetus ngaphakathi kwesibeletho;
  • I-asphyxia yemishini ngesikhathi sokuzalwa kwengane;
  • Ukungashintshi okwanele kwengane;
  • Imiphumela yezinqubo ezithathelwanayo.

Imvamisa, i-hypoglycemia ezinganeni ezisanda kuzalwa ibangelwa ukukhula, ukuqina komzimba esikhathini sokukhulelwa noma i-hypoxia elandelayo.
Imizimba yabo ayikwazi ukuqongelela inani elanele le-glucose, yingakho izimpawu zokuqala ze-hypoglycemia zingabonakala kubo emahoreni okuqala empilo.

Izimpawu zokuqala

I-Hypoglycemia ezinganeni ezisanda kuzalwa iba ngokushesha okukhulu. Kwenzeka ngenxa yomonakalo kumanyikwe, angakwazi ukukhiqiza i-insulin eyanele namanye ama-enzyme. Ngenxa yalokhu, umzimba awukwazi ukuqoqa inani elifanele le-glycogen.

I-Hypoglycemia ezinganeni ezisanda kuzalwa ingabonakala kulezi zimpawu ezilandelayo:

  • Isikhumba esiluhlaza okwesibhakabhaka sezindebe;
  • Pallor;
  • Ukuqina kwemisipha;
  • Isimo esibuthakathaka;
  • Uzwela;
  • Ukukhala okungazelelwe kokumemeza;
  • I-Tachycardia;
  • Ukujuluka ngokweqile;
  • Ukukhathazeka.

Ukuxilonga

Ukuxilonga i-hypoglycemia ezinganeni ezisanda kuzalwa kulula kakhulu. Kulokhu, kwanele ukuthi udokotela enze ukuhlolwa kwegazi okuthuthukile. Basiza uchwepheshe ekuboneni ukubonakaliswa kokuqala kwe-hypoglycemia ebukhali noma evulekile ezinganeni. Imvamisa, lezi zifundo ezilandelayo zenziwa ukuqinisekisa ukutholakala kwale sifo:

  • Ukuhlolwa kwegazi okujwayelekile kwe-glucose;
  • Ukuhlolwa kwegazi okujwayelekile ukuthola inani lama-acid amaningi;
  • Ukuhlolwa kwegazi okujwayelekile kokuthola izinga lemizimba ye-ketone;
  • Ukuhlolwa kwegazi okujwayelekile ukuthola ukunqampuna kwe-insulin egazini;
  • Ukubala kwegazi le-Hormonal ezingeni le-cortisol, elibhekele ukukhula nokukhula komzimba.

Ukwelashwa

Kubaluleke kakhulu ukuthi ukwelashwa kwe-hypoglycemia ezinganeni ezisanda kuzalwa kusheshe. Ukuthola lesi simo enganeni, udokotela usebenzisa imichilo yokuhlola eshesha enquma ukuhlangana kweglucose egazini. Uma inkomba ingafiki ezingeni le-2 mmol / l, khona-ke ingane ithatha igazi ukuze ifundwe isikhathi eside. Ngemuva kokuqinisekisa ukutholakala kwesifo, uchwepheshe ulimaza inani elithile le-glucose ngaphakathi.

Imvamisa, i-hypoglycemia ezinganeni ivela emahoreni okuqala ayi-10 okuphila.

Ukhula ngenxa yokudla okungenamsoco. Ngemuva kokumisa ukuhlaselwa, izimpawu ze-hypoglycemia zinganyamalala ngaphandle komkhondo nemiphumela yomzimba.

Kubaluleke kakhulu ukunamathela kule mithetho elandelayo ekwelashweni kwalesi simo:

  • Awungeke ukuphazamise ngokushesha ukuphathwa kwe-glucose - lokhu kungaholela ekwandeni kwe-hypoglycemia. Ukuqedwa kwenzeka kancane, udokotela wehlisa kancane kancane umthamo wento esebenzayo.
  • Ukwethulwa kwe-glucose kufanele kuqale ngo-6-8 mg / kg, kancane kancane kukhule kube ngu-80.
  • Kuyenqatshelwe ngokuqinile ukufaka i-glucose engaphezu kwe-12,5% emithanjeni yengane.
  • Akunconywa ukuphazamisa ukondla ngesikhathi sokuphathwa kwe-glucose.
  • Uma i-glucose ihanjiswa kowesifazane okhulelwe ukuvikela i-hypoglycemia enganeni yakhe esanda kuzalwa, ukunakekelwa kufanele kuthathwe ukuze kuqinisekiswe ukuthi ukuqina koshukela egazini akukhuphuki ngaphezu kuka-11 mmol / L. ngaphandle kwalokho, kungaholela ekhefeni le-hypoglycemic kowesifazane okhulelwe.

Ngendlela efanele yokwelashwa, udokotela uzokwazi ukuyeka ngokushesha ukuhlaselwa kwe-hypoglycemia enganeni.

Futhi, uma owesifazane okhulelwe ebuka zonke izincomo zikadokotela ozobakhona, uzokwazi nokunciphisa ingozi yokuthola hhayi kuphela ukwehla kokubandakanywa koshukela osanda kuzalwa, kodwa futhi avikele ukuvela kwe-hyperbilirubinemia, erythrocytosis kanye nokuphazamiseka okuhlukahlukene kokuphefumula.

Imiphumela

I-Hypoglycemia ukuphambuka okukhulu ekusebenzeni komzimba, okungaholela emiphumeleni emibi. Ukuhlola ubulukhuni bazo, kwenziwa izifundo eziningi. Benza ukuthi baqonde ukuthi izitho nezinhlelo zezingane zizokhula kanjani ngenxa ye-hypoglycemia yangaphambilini. Ucwaningo oluningi selukhombisile ukuthi, ngenxa yokwehla kwamazinga kashukela, izingane ezisanda kuzalwa ziba nezinkinga ezinkulu ekusebenzeni kwengqondo. Lokhu kuholela ekuthuthukisweni kwezifo zohlelo lwezinzwa, kwandisa ingozi yokuthola isithuthwane, ukukhula kwesimila.

I-hypoglycemia edluliselwe futhi ibonakala ezingeni lobuhlakani bengane namakhono ayo emoto.
Ngokuphawuleka kwandisa amathuba okuthola i-cerebral palsy, ukuhlaselwa kwe-hypoglycemia ngokuzayo. Izingane ezinjalo zibhaliswe ngokukhethekile kuma-polyclinics, zidinga ukunakwa okwengeziwe kudokotela ohambelayo.

Ukuvimbela

Ukuvimbela i-hypoglycemia ezinganeni ezisanda kuzalwa kuqukethe ukudla okufika ngesikhathi futhi okuphelele. Uma uqala ukudla okuhambisana kuphela ezinsukwini ezingama-2-3 kuphela ngemuva kokuzalwa, ubungozi bokukhula ngalesi simo buzoba phezulu kakhulu. Ngemuva kokuba ingane izelwe, zixhunywe kwi-catheter, okuyilapho izithako zokuhlanganiswa zokuqala zethulwa ngemuva kwamahora ayi-6. Ngosuku lokuqala, unikezwa cishe ama-200 ml wobisi lwebele.

Uma umama engenalo ubisi, ingane inikezwa imishanguzo ekhethekile yokungena emzimbeni, umthamo wayo ungaba yi-100 ml / kg. Uma kunengozi eyandayo ye-hypoglycemia, ukugxilwa koshukela egazini kuhlolwa njalo emahoreni ambalwa.

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