I-Glycated hemoglobin (HbA1C) iyinkomba ye-serum biochemical ekhombisa ukugcotshwa kwe-glucose esikhathini esiyizinyanga ezintathu.
Ukuhlaziywa okunjalo kusivumela ukukhomba ubukhona be-pathologies abaningi, kufaka phakathi isifo sikashukela mellitus. Kwenzeka ukuthi imiphumela yocwaningo ikhombise i-hemoglobin ephansi ye-glycated.
Lokhu kukhombisa ukuba khona kwezifo eziningana.
Ngezansi kwe-hemoglobin ejwayelekile ye-glycosylated: Kusho ukuthini?
IHemoglobin ithwala umoya-mpilo odingekayo ukondla izicubu zezitho.
Ngokuphendula kancane okungeyona enzymatic, lo muthi uhlangana noshukela futhi uguqulwa ube yi-glycated hemoglobin. Kukhona ukuhlaziya okhethekile okuveza izinga lale nto.
Kwabesilisa nabesifazane abanempilo, okujwayelekile kungu-4-6%. Ukwehlisa inani lamaphesenti, kunciphisa ingozi yokuthola isifo sikashukela.
Isikhombi esingafinyeleli emkhawulweni ophansi wesilinganiso sibonisa ukuthi amaseli wezicubu awantula i-oksijini, kanti nokuhlushwa kwegluceptor emzimbeni kwehliswa.
Kungani i-glycated hemoglobin yehlisiwe: izimbangela ezivamile
Ukwehla kwe-HbA1C kuwuphawu lwe-pathological. Lesi simo senzeka ngezizathu ezahlukahlukene.
Imvamisa, izinto ezinjalo ziholela kwinani elingezansi kwelejwayelekile:
- ukumpompela igazi noma ukumpontshelwa nge-plasma. Ngenxa yale nqubo, i-HbA1C ixutshwe nengxenyana evamile engaxhunyiwe kuma-carbohydrate;
- ukuntuleka kwe-adrenal;
- ukulahleka okukhulu kwegazi. Kanye ne-hemoglobin ejwayelekile, nayo ilahlekile;
- i-hypoglycemia yesikhathi eside ngenxa yendlala noma ukuphazamiseka kwe-endocrine;
- ukwakheka kwezimila kumanyikwe. Ukuqunjelwa ngokweqile kwe-hormone kuvusa umbuso we-hypoglycemic;
- izinkinga ku-hypothalamus;
- ukungahambi kahle kwe-hepatic (i-hepatitis, ukuntuleka kokusebenza);
- ukuba khona kwezifo ezingajwayelekile zofuzo (isifo seForbes, i-Girke, ukungabekezeleli kwe-fructose);
- i-hemolytic anemia. Le yi-pathology lapho isikhathi esimaphakathi sokuba khona kwamaseli abomvu egazi sincishisiwe. Phambilini, amangqamuzana ane-hemoglobin ye-glycated nawo ayafa;
- ukusebenza ngokweqile ngokomzimba.
Kwabesifazane ngesikhathi sokukhulelwa, iphesenti eliphansi le-HbA1C liyindlela evamile. Lapho uthwala ingane, isizinda se-hormonal sishintsha, kuvela i-anemia. Into esemqoka ukuvimbela ukwehla okukhulu kulesi sikhombisi.
Izimbangela ze-Low HbA1c kanye noshukela wegazi kwisifo sikashukela
Ku-diabetes, i-hemoglobin ye-glycated ivame ukuphakanyiswa. Ukushoda kwe-hormone ye-insulin, ukungatheleleki kwamaseli kule nto kubangela ukunqwabelana kwe-glucose ku-serum, ukusabela kweMayer kanye nokwakhiwa kweHbA1C tata.
Kepha kunezimo lapho ukuhlaziya kukhombisa ukwehla kwepharamitha.
Imvamisa, lokhu kungenxa yokwelashwa okungalungile kwezidakamizwa, ukungahambelani nemiyalelo kadokotela. Izimbangela ze-HbA1C ephansi kubantu abane-pathologies amafomu okuqala nokwesibili ahlukile.
Uhlobo olu-1
Uhlobo lokuqala lwesifo sikashukela lubhekwa njenge-insulin. Ngalesi sifo, umuntu uyaphoqelelwa ukuthi afake i-hormone nsuku zonke, engakhiqizi i-pancreas.
Izinga eliphansi le-HbA1C libangelwa:
- ukusetshenziswa kwemithamo ephezulu ye-insulin hormone;
- ukondleka kwesikhathi eside kwe-carb;
- isifo sikashukela se-nephropathy.
Izinhlobo ezi-2
Uhlobo lwesibili sikashukela ifomu elizimele le-insulin. Kulokhu, ama-pancreas akhiqiza i-hormone, kepha ngesilinganiso esanele. Umuntu kufanele abambelele ekudleni okuqinile noma asebenzise izidakamizwa ezinciphisa ushukela.
Iqoqo eliphansi le-HbA1C libonwa nge:
- izidakamizwa ezidla ngokweqile ezinciphisa ushukela we-plasma;
- i-insulinoma (isimila se-pancreatic);
- ukudla okungafanele (ukusetshenziswa kokudla okuphansi kwekhalori);
- ukwehluleka kwezinso.
Izimpawu nezimpawu
Lapho izinga le-HbA1C liqala ukuncipha, umuntu uba nezimpawu zesimo sesimo se-hypoglycemic. Izimpawu zokuthikamezeka kubantu abanesifo sikashukela kuthiwa ziningi.
Uma okuqukethwe kwe-hemoglobin ye-glycated kwehla ngaphansi kwe-4%, khona-ke ukubonakaliswa okunjalo kwenzeka:
- ubuthakathaka obukhali;
- indlala enkulu;
- ukuthuthumela emilenzeni;
- ukujuluka ngokweqile;
- ikhanda elinzima;
- ukhubazeka okubukwayo (umuntu ubona zonke izinto ngasese);
- ukuzindla kwenhliziyo;
- Isiyezi
- isasasa, ulaka;
- ukungazi kahle;
- ubukhulu bolimi nezindebe.
Uma izimpawu eziphansi zokuqukethwe kwe-HbA1C ephansi zibhekwa, udinga ukubheka amazinga kashukela nge-glucometer yasekhaya, nikela ngegazi kusuka emthanjeni noma emunweni ukuhlolwa kwelabhorethri.
Uma inkomba ingaphansi kuka-3.3 mmol / l, khona-ke kukhona i-hypoglycemia, futhi udinga ukudla umkhiqizo we-carbohydrate (ngokwesibonelo, isipuni soshukela noma uju). Kungakuhle futhi ukuthi uhlaziye ukuhlaziya i-hemoglobin ye-glycated.
Yini ingozi yokunciphisa i-HbA1c egazini?
Uma i-hemoglobin ye-glycated iqala ukuncipha, kufanele kwenziwe ukuhlolwa okuphelele. Lesi simo siyingozi ngoba ngemuva kwesikhashana umsebenzi wezitho zangaphakathi uphazamiseka.
Okuthintekile:
- imithambo yegazi. Izindonga zemithambo yegazi ziba kancane kakhulu, imisebe yelimen. Lokhu kuholela indlala yomoya-mpilo. Kulesi simo, kunethuba elandayo lokushaywa unhlangothi, ukushaya kwenhliziyo noma enye i-pathologies yemisipha yenhliziyo, yemithambo yegazi. Imvamisa lokhu kubangela ukufa;
- i-epidermis. Ngenxa yokugeleza kwegazi okunganele, ukusikeka kanye namanxeba kuphulukisa kancane, ifomu lezilonda ezingaqondakali. Lokhu kuthuthukisa ukuthuthukiswa kwezifo ezithathelwanayo;
- izinso. Isitho esibhangqiwe siqala ukusebenza ngokungalungile, ukusebenza kwawo kuyancipha;
- uhlelo lwangaphakathi lwezinzwa. Ukuzwela ezingalweni nasemilenzeni kulahlekile. Umuntu angakhononda ngokusinda okungapheli nobuthakathaka emilenzeni.
Ungayilungisa kanjani izinkomba?
Ungangezelela inkomba ye-hemoglobin ye-glycated ngezindlela ezihlukile: ngokwelashwa, ngokuzivocavoca umzimba, ukondleka okufanele, nokukhathalela uhlelo lwezinzwa. Odokotela batusa indlela ephelele yokwelashwa.
Ukudla okufanele
Ukwenza kube ngokwejwayelekile ukugcwala kwe-hemoglobin ene-glycated, kubalulekile ukudla ukudla okunempilo. Kuyadingeka ukunamathela ekudleni. Ukudla kukhiqizwa uchwepheshe wesiguli ngasinye ngawodwana.
Kunconyiwe:
- kudla izithelo nemifino eminingi. Bakhulisa izinga le-fiber kanye noshukela emzimbeni futhi bathuthukise isimo sesiguli. Ibonisa ubhanana, izindamu;
- phuza ubisi lwe-skim, iyogathi. Imikhiqizo enjalo iqukethe i-Vitamin D, i-calcium, edingekayo ukuqinisa u-cartilage nezicubu zamathambo. Zibuye zenze ukugayeka kokugaya kanye noshukela wegazi;
- udle amantongomane, inhlanzi. Aqukethe ama-omega-3 acid, anciphisa ukumelana nama-hormone e-insulin, athuthukisa ukusebenza kwemisipha yenhliziyo;
- engeza i-sinamoni powder ekudleni neziphuzo. Iyanciphisa ukumelana ne-insulin;
- nciphisa ukudla kwakho okungenamsoco nokudla okunamafutha. Imikhiqizo enjalo ithinta kabi isimo semikhumbi;
- khipha kwimenyu ukudla okusheshayo, ama-potato chips, ushokoledi, u-ayisikhilimu, ukudla okuthosiwe neziphuzo zekhabhoni.
Umsebenzi womzimba
Ukuvivinya umzimba ngokulinganisela kunconywa kaningana ngesonto. Isikhathi esiphezulu sesifundo imizuzu engama-30.
Imithwalo yamandla evinjelwe, iyasebenza. Baholela ekunciphiseni ngokushesha kwezitolo ze-glycogen futhi kuvuse ukubonakala kwezimpawu ze-hypoglycemia.
Kungcono ukwenza ukubhukuda, ukuhamba, i-yoga, ukwenza izivivinyo zokuphefumula. Ukuzivocavoca kuqinisa izicubu zomzimba, kwenza amasosha omzimba akho ukumelana nezifo ezahlukahlukene.
Kunconywe ukuthi uthathe okuthile okumnandi nawe ukuze uthathe izinyathelo zokuthuthukisa isimo sakho uma amazinga kashukela ehla.
Ukunakekelwa kwesistimu enobuhlungu
Ukuqoqwa kwe-hemoglobin ye-glycated ikakhulu kuya ngesimo somuntu sengqondo.Ukukhathazeka, ukucindezeleka okungapheli kuthinta isimo semithambo yegazi, inhliziyo.
Ukuzilibazisa, ukuzindla, ukubukela izinhlelo zethelevishini, ukulalela umculo wakho owuthandayo, ukuhamba kusihlwa kuyakhonjiswa.
Ukwenza ngcono isimo sohlelo lwezinzwa, izidakamizwa ezingathathelwa phezulu zingathathwa. Kubalulekile ukufunda ukuthi ungakhululeka wedwa, umelane nengcindezi.
Amavidiyo ahlobene
Mayelana ne-hemoglobin ephansi ye-glycated kuvidiyo:
Ngakho-ke, izinga eliphansi le-hemoglobin libhekwa njengokujwayelekile futhi libonisa ukuthi umuntu akanakho ukuthambekela kwesifo sikashukela. Kepha ukwehla okukhulu kwalesi sikhombisi kuyithinta kabi inhlala-kahle nomsebenzi wezitho eziningi zezitho.
Uma uhlangabezana nezimpawu ze-hypoglycemia, kunconywa ukuthi kuhlolwe igazi ngoshukela kanye ne-HbA1C. Kungenzeka ukulawula okuqukethwe kwe-hemoglobin ye-glycated ngokudla, ukwenza izivivinyo zomzimba, nokuvikela uhlelo lwezinzwa.
