I-LIPODYSTROPHY KU-MELLITUS YESIFO SIKASHUKELA: UKWELASHWA NOKUVIMBELA UKWELASHWA KWE-INSULIN

Send

Isifo sikashukela mellitus sibonakala ngokuhlukahluka okukhulu ngokwanele kwezindlela zesifo. Enye yazo isifo sikashukela i-lipoatrophic.

Lesi sifo sihluke ngesifo sikashukela esingaqondakali esithombeni esihlukile somtholampilo. I-Lipodystrophy kwisifo sikashukela iyinkinga eyinkinga edinga ukunakwa okusondelene kochwepheshe.

Siyini isifo sikashukela se-lipoatrophic?

Ngale hlobo lokuxakeka, izinqubo ziyavela eziholela kokungabikho kwezicubu ze-adipose esigulini. Isifo sikashukela se-Lipoatrophic sibonakaliswa ukumelana okuphezulu komzimba kumalungiselelo we-insulin kanye nokwanda kwesibindi, okuvame ukuholela kwisifo sokuqina kwesibindi kanye nezinye izifo zaso.

Okunye futhi okuwukungabikho kwe-ketosis yesifo sikashukela kanye ne-hypermetabolism ene-gland yegilo esebenza ngayo. Ezinganeni ezisanda kuzalwa, uphawu oluyinhloko lungaba yi-adipose tis dystrophy, bese kuthi isifo sikashukela siqhubeke phakathi kweminyaka eyi-10 ngisho eyi-15 elandelayo.

IGynoid lipodystrophy

Kwabadala, ngakolunye uhlangothi, ukuqala kwesifo sikashukela kuyinhloko, futhi i-lipodystrophy ivela eminyakeni eminingana ngemuva kokutholwa kokuntuleka kwe-insulin, imvamisa ngemuva kokugula kwegciwane. Izinguquko okuvezwa izicubu zazo ezincanyana kanye ne-collagen zisheshe zibonakale.

Imvamisa ukukhula kwabo kuhlotshaniswa nokwaziswa kwemijovo ye-insulin. Kwesinye isikhathi i-pathology iba emva kwesikhashana ngemuva komjovo. Futhi kwezinye iziguli, kunalokho, kuvela iminyaka eyi-5 noma eyi-10 ngemuva kokuqala kokuphathwa kwe-insulin.

Izinhlobo ze-insulin lipodystrophy kushukela

Izizathu zokuthuthuka kwale nqubo namanje azikaziwa.

Ngokuqiniseka okuphezulu kakhulu, uhlobo lwe-lipoatrophic lwesifo sikashukela lungahlukaniswa yisifo esingafakwanga.

Umehluko omkhulu phakathi kwalezi zinhlobo ezimbili ukungabi khona kwe-musstr dystrophy esimweni sokuqala esingenakuqedwa komzimba okuqongelela amafutha omzimba. Amafutha we-subcutaneous ayaqhubeka anyamalale futhi angazibutheleli esimweni sokuqukethwe kwamafutha aphezulu ekudleni kweziguli.

Imvamisa, lokho okubizwa nge- atrophic lipodystrophy kukhula. Kubonakala ngokungabikho kwezicubu ze-adipose ezikhula ezindaweni zokulawulwa kwe-insulin ejwayelekile. Ngaso leso sikhathi, kumasayithi wokujova, izilonda zesikhumba nazo ziyaqapheleka, zibonakala ngokucacile esweni elinqunu.

Uhlobo lwesibili lwe-atrophy kwisifo sikashukela yi-lipohypertrophy. Kubangelwa ukufakwa kwe-hypertrophic yamafutha ezindaweni zomjovo. Ngenxa yalokhu, kwakheka ama-lipomas, aziwa kakhulu ngokuthi "wen".

I-Lipohypertrophy iholela ekujikelezweni kwegazi okungekuhle futhi ikwenza kube nzima ukumunca i-insulin ngemuva kokujova.

Izizathu eziphambili zentuthuko

Ngokuqinisekile imbangela yale nto ayikaziwa. Kodwa-ke, ochwepheshe bahlonza izici ezingavusa kakhulu ukuthuthuka kwalesi sifo.

Izimbangela ze-lipodystrophy zifaka:

ukulimala njalo kwezicubu ngesikhathi sokujova;
ukusabela komzimba kwezicubu kumuthi;
izinguquko ngemuva kwesizinda se-hormonal sesiguli.

Izici ezandisa ubungozi be-pathology zihlanganisa nokukhuluphele, izifo ezithathelwanayo, ukungondleki kanye nokuphila kokuhlala phansi. Imijovo ephula umthetho nayo inengxenye kwi-lipodystrophy.

Ikakhulu, ukungena ekubanjweni kotshwala kubangela ukushiswa kwamakhemikhali amancane futhi kunomthelela ekuthuthukiseni i-pathology. Kukhona i-hypothesis yokuthi ukuthuthukiswa kwe-lipodystrophy nakho kuthinteka ekuphenduleni kwe-immune-metabolic yomzimba ekuphathweni kwe-insulin yangaphandle kuyo.

Mhlawumbe kungenxa yokuthi ukucutshungulwa okuphoqelelwe ngumzimba we-"" angaphandle "we-hormone okwenziwa ukuthi inqubo ye-pathological lipoid metabolism yaqala.

Ngaphezu kwalokho, ukungatheleleki komuntu kungasabela engxenyeni ye-insulin engena ungqimba lwamafutha angaphansi njenge-antigen yakwelinye izwe.

Ngenkathi yokubhujiswa kwayo, izicubu ze-lipoid nazo zilimala.

Izimpawu ezejwayelekile kwabanesifo sikashukela

Kubalulekile ukuqaphela i-lipodystrophy ngesikhathi esifanele futhi ufune usizo ngesikhathi.

Ekuthuthukisweni kwe-pathology, izinkomba ezinjengokubomvu kanye nokuncipha kwesikhumba ezindaweni ezivuleke kakhulu kumjovo kuyimpawu.

Kulokhu, kungenzeka ukukhomba ngokucacile umngcele wendawo ethintekile yomzimba. Ngokuhamba kwesikhathi, ukuzwela kwale ndawo yesikhumba kuya ekulimaleni okuhlukahlukene kuyanda. Ngisho ukusikeka okuncane nokuqhekeka kuphulukisa kabi, izilonda ezingahlanjululwa zingaqhamuka, futhi zibe nesihluku uma zingalashwa.

Ngokuhamba kwesikhathi, i-lipodystrophy yasendaweni iqala ukuthinta umzimba emzimbeni. Cishe i-25% yeziguli, yikho ngqo imbangela yokungamelana ne-insulin. Ngaphezu kwalokho, ukuthuthukiswa kwalesi sifo kushintsha isikhathi sokufaka isidakamizwa. Lokhu kugcizelela kakhulu ukubalwa komthamo ofanele, ikakhulukazi ukusetshenziswa kwe-insulin esebenza isikhathi eside.

Ezimweni ezingavamile, i-atrophy of tishu ye-adipose iba ibanga elithile ukusuka kumasayithi womjovo. Lesi simo senza ukutholakala kwegciwane kube nzima ekuqaleni kwesigaba sokuqala futhi kujwayelekile ikakhulukazi kwabesifazane.

Izici zokwelapha

Uma kutholwa i-lipodystrophy, kusetshenziswa iqoqo lezinyathelo ezihlose ukuqeda izimbangela ze-pathology nasekunciphiseni imiphumela yalo emibi.

Okokuqala, ukufakwa kokulungiswa kwe-insulin kuyenziwa. Iphephe kakhulu ihlanjululwa kakhulu i-monoinsulin.

Ngokweminye imibiko, i-hormone ekhiqizwa indlala yezinkomo imvamisa ibangela i-pathologies emzimbeni. I-Electrophoresis yezindawo ezithintekile, kufakwa isicelo sikaphalafini, inductometry. Izindlela ezisebenza kahle ukwelashwa kwe-ultrasonic yezindawo ezithintekile.

Ukuguquguquka kufinyelela izicubu ezijulile futhi kuvuse ukugeleza kwegazi nokugaya. Futhi, umphumela othile ulethwa ukusetshenziswa kwamafutha endawo aqukethe amalungiselelo e-hormonal.

Ukubaluleka kokushintsha amasayithi womjovo wokwelashwa kwe-insulin

Kokubili ekwelashweni kwe-pathology nokuvimbela kwayo, kubalulekile ukuphatha kahle izidakamizwa eziqukethe i-insulin.

Kuyadingeka ukuguqula amasayithi womjovo. Ephuzwini elifanayo, ukujova akungenqulwa kube kanye ezinyangeni ezimbili.

Izinga lokushisa lomuthi nalo libalulekile. Kungcono ukusebenzisa i-insulin, efudumele kuya kuma-degrees angama-36. Kwamukelekile ukusebenzisa umuthi ngokushisa kwasekamelweni, kodwa hhayi kubanda.

Indawo yomjovo kufanele ihlaselwe ngotshwala, kepha kuyadingeka ukulinda kuze kuqhume.

Umuthi kufanele uphathwe kancane futhi ngokujulile ngokwanele. Isixazululo esihle ukuthenga iphampu ye-insulin noma injekishini ekhethekile enjenge-pen. Kubalulekile ukuthi ushintshe inaliti ngaphambi komjovo ngamunye.

Ukuvimbela ukuvimbela izinkinga zesifo sikashukela

Ngaphezu kwezindlela ezichazwe ngenhla, eminye imithetho kumele ilandelwe ukuvikela ubunzima.

Ukugcina ibhalansi yamanzi efanelekile kubalulekile.

Kungakufanele ukuthi udle amalitha ama-3 koketshezi (kufaka phakathi izifundo zokuqala), ngenkathi unikeza ukuthandwa kwamanzi emvelo nekhwalithi.

Kubalulekile ukulandela indlela odla ngayo, ukuzivocavoca umzimba olula. Kubalulekile ukulawula isisindo sakho, uma kunesidingo, ukuze unciphise isisindo somzimba usebenzisa indlela yokudla ebekwe udokotela wakho.

Amavidiyo ahlobene

Izimbangela kanye nokwelashwa kwe-lipodystrophy ku-mellitus yesifo sikashukela:

Ukuhambisana nale mithetho, kanye nokuphathwa kahle kwe-insulin, kuzovikela inkinga enobungozi njenge-dystrophy yezicubu ze-adipose, futhi kungabi nokwenziwa okuyinkimbinkimbi futhi kube buhlungu ukwelashwa

Send