Uhlelo lwe-hematopoietic lwenza imisebenzi eminingi eqinisekisa umsebenzi obalulekile womzimba. Ukusuka enhliziyweni ngemithambo nemithambo yegazi, igazi lithwele izakhamzimba nomoya-mpilo odingekayo kwizitho nezicubu.
Imvelo ihlelwe kahle kangangokuba uhlelo lwe-hematopoietic luyakwazi ukuzilawula ngokuzimele.
Isibonelo, ngezici ezahlukahlukene zokuphazanyiswa kwangaphandle komzimba noma izinqubo zangaphakathi ze-pathological, inesibopho sokuphepha okuhlobene nokwakheka kwegazi kanye nomthamo wezinto zezinto ezifakiwe kuzo.
Ukuphambuka okuvame kakhulu okuhlobene ngokuqondile noshintsho ekwakhekeni kwegazi ukwephulwa kokuqina kwalo. Kwesinye isikhathi, noma ukusikwa okukhanyayo, kunzima ukuyeka ukopha, futhi umuntu angalahlekelwa inani elikhulu legazi. Lokhu kuvame ukukhombisa ukubumbana kwayo okuphansi.
Kodwa-ke, inqubo ehlukile nayo ibonwa lapho igazi liba mnene. Ngokwesibonakaliso esifanayo, uFraxiparin unqunyelwe. Zombili lezi zimo zingukuphambuka okungathi sína okudinga ukubhekwa ngokucophelela ngumuntu kuyo yonke impilo.
UFraxiparin: yini?
I-Fraxiparin isidakamizwa esinciphisa umsebenzi wokugcwala kwegazi futhi sinciphise amathuba okuba ne-vascular thrombosis.
Ukuqanjwa okuyinhloko kwalesi sidakamizwa kufaka into etholakala ngokwezifo ezithweni zangaphakathi zezinkomo.
Lesi sidakamizwa sikukhuthaza ngokuqinile ukuncipha kwegazi futhi sikhulise ukuqina kwamapulangwein, ngaphandle kokuthinta ukusebenza kwawo.
Iqembu lezemithi
Ungowokuqondiswa ngqo kwama-anticoagulants (ama-heparins) wesakhiwo semisindo ephansi.Lolu uhlu lwezidakamizwa ezithinta uhlelo lwe-heestasis, olubhekele ukuqina kwegazi.
Ngaphezu kwalokho, ihloselwe ukuvimbela ukwakheka kweziqeshana zegazi ezinegalelo kwizilonda zamaseli e-atherosulinotic.
Ama-heparin asisindo esincane aphansi kakhulu futhi anezinzuzo eziningi: ukumuncwa ngokushesha, isenzo eside, umphumela othuthukisiwe. Ngenxa yalokhu, umthamo wesidakamizwa ukuze uthole umphumela ongcono kakhulu wehliswa.
Ukuqunjelwa umuthi cishe kuphelele (ngaphezu kwama-85%). Isebenza kahle kakhulu emahoreni angama-4-5 nangokwelashwa kwe-course, engeqi ezinsukwini eziyi-10.
Into esebenzayo
Isithako esikhulu esisebenzayo esiyingxenye yeFraxiparin yi-calcium nadroparin. Umphumela wayo uqondiswe ezicini lapho ukuhlangana kwegazi ngokuqondile kuncike khona.
Khipha ifomu
I-Fraxiparin itholakala kuphela ngefomu le-liquid kuma-ampoules. Yakhelwe umjovo ongama-subcutaneous. Kungcono ukujova umuthi endaweni ephakeme..
Isidakamizwa uFraksiparin 0.3
Inaliti ifakwa kwezicubu zesitho sangasese esishubile ngokuqinile (hhayi engela). Okokuqala, kuyadingeka ukuphina isibaya sesisu esiswini ngesithupha nesandule sangaphambili endaweni yengxenye lapho kwethulwa khona isethulo, futhi ungakuvumeli ukuthi kudlule kuwo wonke umjovo.
Ngokusetshenziswa isikhathi eside, ngemithambo yegazi ecashile eyakhelwe endaweni yomjovo, ukuphatha engxenyeni yowesifazane kuvunyelwe. Ngemuva kwenqubo, ungagcobhozi indawo yomjovo.
Umthamo
Umthamo ubalwa ngokuya ngesisindo somzimba wesiguli, iminyaka, izifo ezihlobene nemiphumela yokuhlolwa.
Umuthi uyatholakala ngesimo samabhulukwe anama-ampoules we-0,1 ml, 0,3 ml, 0,4 ml, 0,6 ml, 0,8 ml. Ngaphezu kwe-Fraxiparin yendabuko, isidakamizwa i-Fraxiparin Forte okwamanje sisemakethe yezokwelapha.
Kuqukethe into esebenzayo ngendlela egxile kakhulu futhi, ngakho-ke, umthamo uyancishiswa. Lokhu kufanele kunakwe iziguli ezenza imijovo hhayi esibhedlela, kodwa ekhaya.Ngokuvimbela i-thrombophilia nangesikhathi sokukhulelwa, odokotela banquma umthamo we-0.3 ml.
Kokunye okuxilongiwe, inani lezidakamizwa elihanjiswa kunqunywa izibalo ngokuya ngesisindo somzimba sesiguli. Uma isisindo sesiguli singaphansi kwama-50 kg, khona-ke hhayi ngaphezulu kwe-0.4 ml sisetshenziswa kanye ngosuku. Ngobunzima obungamakhilogremu angama-50 kuye kwangama-70 - u-0.5 noma u-0,6 ml. Imijovo inqunywa kanye yokwelapha inkambo yezinsuku ezingekho ngaphezulu kwe-10.
Ngengozi ekhulayo ye-thrombosis - ukwenza isimo sezinkomba sibe ngesifanayo.
Ezinganeni nasentsheni, ukwethulwa komuthi kuvunyelwe ezimweni ezihlukile, ngoba kuba nzima ukusungula umthamo womuthi.
Abantu asebekhulile abadingi ukulungiswa kwamthamo uma ukungasebenzi kwezinso kungasungulwa.
Okunqunyelwe i-Fraxiparin: izinkomba
I-Fraxiparin isetshenziswa kwezokwelapha ekwelapheni nasekuvimbeleni izifo ezilandelayo:
- I-thromboembolism - Ukuqhuma okukhulu kwemithambo yegazi yi-thrombus;
- izinkinga ze-thromboembolic ngesikhathi sokuhlinzwa kanye nokwelashwa kwamathambo ezigulini ezisengozini;
- ngesikhathi senqubo ye-hemodialysis (ukuhlanzekiswa kwegazi okungeziwe ekuhlulekeni kwezinso okungamahlalakhona);
- nge-angina engazinzile kanye ne-myocardial infarction;
- lapho uthwala ingane ngemuva kwenqubo ye-IVF;
- phakathi kwanoma yikuphi ukuhlinzwa kokuhlinzwa ezigulini ezihlushwa ukuqina kwegazi.
Kungani i-Fraxiparin ibekelwe i-IVF?
Inqubo yokuqina kwegazi ingenzeka kubo bobabili ubulili. Kodwa-ke, kubo bobabili, lokhu akuyona into ejwayelekile.
Kwabesifazane, le nqubo ibhekwa kaningi, ngoba ngokwemvelo yabo igazi labo ligxiliswa kakhulu ekuvikeleni ukuya esikhathini.
Ngesikhathi sokukhulelwa, lonke uhlelo lokujikeleza kwegazi luyaphoqelelwa ukujwayela isimo samanje: umthamo wokujikeleza kwegazi futhi, ngenxa yalokho, inethiwekhi yonke yemithambo yegazi iyanda. Ngesikhathi sokukhulelwa, ukuqina kwegazi kungaba yinkinga yangempela, kuthinte kakhulu inhlala-kahle yowesifazane.
Ngaphezu kwalokho, ngokushesha ngaphambi kwenqubo yokuzalwa, igazi lijula kakhulu ngangokunokwenzeka ukuze kugweme ukulahleka ngokweqile kwegazi, okungahle kube yingozi empilweni kamama. Noma kunjalo, i-Fraxiparin ayinqunyelwe ngesikhathi sokuqanjwa kwemvelo, ngoba kancane kancane umzimba uyazihlanganisa phakathi nenqubo yokwakhiwa kabusha.
Ngenqubo ye-IVF, umuntu wesifazane unzima kunokukhulelwa okujwayelekile.
Ukuqina kwegazi kuyinkimbinkimbi ngethonya lezidakamizwa ze-hormonal, ngaphandle kwalo ngaphandle kokuvundiswa ngempumelelo akunakwenzeka. Ngenxa yalokhu, kunengozi yejazi legazi, elingalimaza impilo yomama nengane. Ukuvimbela lokhu, anticoagulants enqunyelwe.
Ngesikhathi sokukhulelwa nge-IVF, i-Fraxiparin inqunyelwe:
- ukuncipha kwegazi;
- ukuvikela ukuvikeleka kwemithambo yegazi ngokwakhiwa kwe-thrombotic;
- ngesakhiwo esihle se-placenta, ekhipha ukuhanjiswa kwezinto ezisuka emzimbeni womama ziye fetus;
- Ukubekwa okufanele nokunamathiselwe kombungu.
Amavidiyo ahlobene
I-Obstetrician-gynecologist mayelana ne-thrombophilia ngesikhathi sokukhulelwa:
Uma ngesikhathi sokukhulelwa, odokotela bazothola ukuthi umzimba uqobo waqala ukukhiqiza ama-coagulants wemvelo, khona-ke inqubo yokujova iyakhanselwa kuze kube yilapho iqoqo elilandelayo lihlaziywa.
