Umuthi i-Glucophage umuthi osuselwa ku-metformin hydrochloride, okhombise imiphumela emihle ekwelashweni kwesifo sikashukela esingancikeli i-insulin kwiziguli ezikhuluphele.
Ngokuvamile kunqunywa lapho ukwelashwa kokudla kanye nokuzivocavoca komzimba kunganikeli umphumela oyifunayo.
Kungenzeka yini ukunciphisa isisindo nge-glucophage
Ukudla okungena emzimbeni kuholela ekukhuphukeni okukhulu kwe-glucose. Uphendula ngokuhlanganisa i-insulin, obangela ukuguqulwa kwe-glucose ibe ngamaseli wamafutha nokuma kwawo ezicutshini. Umuthi olwa nezidakamizwa i-Glucofage unomphumela wokulawula, ubuyisa izinga leshukela egazini libuyele kokujwayelekile.
Isakhi esisebenzayo somuthi yi-metformin, sinciphisa ukuwohloka kwama-carbohydrate futhi sijwayeza i-lipid metabolism:
- oxidizing fatty acids;
- ukukhulisa ukuzwela kwama-receptors ku-insulin;
- ukuvimbela ukwakheka kweglucose esibindini kanye nokwenza ngcono ukungena kwalo izicubu zomzimba;
- kusebenze inqubo yokubhujiswa kwamaseli wamafutha, kwehlise i-cholesterol.
Ukusetshenziswa kwe-Glucofage kuhlanganiswa nokudla okuphansi kwe-carb kunikeza umphumela omuhle wokulahlekelwa kwesisindo. Uma ungalandeleli imikhawulo yemikhiqizo ephezulu ye-carb, umphumela wokuncipha kwesisindo uzoba mnene noma ungabi nhlobo.
Lapho usebenzisa lo muthi kuphela ngokuncipha kwesisindo, wenziwa ngokuhamba kwezinsuku eziyi-18 kuya kwezingu-22, ngemuva kwalokho kuyadingeka ukuthatha ikhefu elide izinyanga ezi-2-2 bese uphinda inkambo futhi. Umuthi uphuzwa ngokudla - izikhathi ezingama-2-3 ngosuku, ngenkathi uphuza amanzi amaningi.
Khipha amafomu
Ngaphandle, i-Glucophage ibukeka njengamathebhulethi amhlophe, amafilimu aphekwe kathathu, i-convex.
Kumashalofu ekhemisi, kuvezwa izinguqulo eziningana, ezahluka ngokuxhunywa kwento esebenzayo, mg:
- 500;
- 850;
- 1000;
- Isikhathi eside - 500 no-750.
Amacwecwe ajikelezayo ka-500 no-850 mg abekwa emabhulini angama-10, 15, 20 ama-pcs. kanye namabhokisi amakhadibhodi. Iphakethe elilodwa le-Glucofage lingaqukatha ama-2-5. Amathebhulethi ayi-1000 mg angama-oval, anezinothi eziguqukayo ezinhlangothini zombili kanye nomaki "1000" kwelinye.
Abuye afakwe emabhulashini ama-pcs ayi-10 noma ayi-15., Agcwele emakhadini amakhadibhodi aqukethe kusuka ku-2 kuya ku-12 amabhuloka. Ngaphezu kwezinketho ezingenhla i-Glucofage, emashalofini ekhemisi futhi iveze iGlucofage Long - umuthi onomphumela owenzeka isikhathi eside. Isici sayo esiyimpawu ukukhululwa kancane kwengxenye esebenzayo nesenzo eside.
Amathebulethi amade awumbala obomvana, omhlophe, kokunye kokuphezulu anophawu olukhombisa okuqukethwe kwento esebenzayo - 500 no-750 mg. Amacwecwe amade angama-750 abhalwe nangokuthi "Merck" ngakolunye uhlangothi lwesikhombisi sokuhlushwa. Njengawo wonke umuntu, zifakwe emabhulini ezingcezu eziyi-15. futhi igcwele emabhokisini amakhadibhodi ezinhlamvu ezingama-2-4.
Okuhle nokubi
Ukuthatha i-Glucophage kuvimbela i-hypoglycemia, ngenkathi kunciphisa izimpawu ze-hyperglycemia. Ayithinti inani le-insulin ekhiqizwayo futhi ayakhiqizi umphumela we-hypoglycemic ezigulini ezinempilo.
I-Glucophage 1000 amaphilisi
I-Metformin equkethwe umuthi ivimbela ukwakheka kwe-glucose esibindini, yehlise amandla ayo okuthola izitho zangasese, nokumuncwa kwamathumbu. Ukudla nge-Glucofage ngokwejwayelekile kwenza i-lipid metabolism, ekuvumela ukuthi ugcine isisindo sakho ungaphansi kokulawula futhi unciphise kancane.
Ngokusho kwezifundo zokwelapha, ukusetshenziswa kwe-prophylactic yalesi sidakamizwa esifundazweni sangaphambi kwesifo sikashukela kungavimbela ukukhula kwesifo sikashukela sohlobo 2.
Umphumela wokuthatha i-Glucofage ungaba umphumela osuka ku:
- Amapheshana wesisu. Njengomthetho, izimpawu eziseceleni zivela ezigabeni zokuqala zokwamukelwa futhi kancane kancane zinyamalale. Ichazwa yisicanucanu noma isifo sohudo, isifiso sokudla. Ukubekezelela umuthi kuyathuthuka uma umthamo wawo ukhuphuka kancane kancane;
- uhlelo lwezinzwa, kuboniswe ngesimo sokwephulwa kwemizwa yokunambitha;
- i-bile duct nesibindi. Kuboniswa ukungasebenzi kwezitho, i-hepatitis. Ngokukhanselwa komuthi, izimpawu ziyanyamalala;
- umzimba - Kungenzeka ukunciphisa ukumuncwa kwe-vitamin B12, ukuthuthukiswa kwe-lactic acidosis;
- isikhumba esikhulayo. Ingabonakala esikhumbeni ngokuqhuma, ukulunywa, noma i-erythema.
Ukwephulwa kokuthathwa kwe-Glucophage ubukhona besiguli:
- enye yezindlela zokusweleka - inhliziyo, ukuphefumula, i-hepatic, i-renal - CC <60 ml / min;
- ukushaya kwenhliziyo;
- isifo sikashukela sikashukela noma i-precoma;
- ukulimala nokuhlinzwa;
- utshwala;
- i-lactic acidosis;
- hypersensitivity kuzakhi.
Awukwazi ukuhlanganisa ukusetshenziswa kwalesi sidakamizwa nokudla okuphansi kwekhalori, futhi kufanele wenqabe ukusithatha ngesikhathi sokukhulelwa. Ngokuqapha, unqunyelwe ukulengisa abesifazane, asebekhulile - ngaphezulu kweminyaka engama-60, abantu abasebenzayo ngokomzimba.
Ungayithatha kanjani?
IGlucophage yenzelwe ukuphathwa komlomo nsuku zonke ngabantu abadala nezingane. Umthamo wansuku zonke unqunywa udokotela.
IGlucophage ivame ukubekelwa abantu abadala abanokuhlushwa okuphansi okungama-500 noma ama-850 mg, i-1 ithebhulethi kabili noma kathathu ngosuku ngesikhathi sokudla noma ngemuva kokudla.
Uma kunesidingo sokuthatha imithamo ephezulu, kunconywa ukuthi ushintshe kancane kancane uye kwi-Glucofage 1000.
Kubantu asebekhulile, umthamo ukhethwa ngawodwana, kucatshangelwa ukusebenza kwezinso, ezizodinga izikhathi ezi-2-4 ngonyaka ukwenza izifundo nge-creatinine. I-Glucophage yenziwa ekwelashweni kwe-mono-futhi inhlanganisela, ingahlanganiswa neminye imithi ye-hypoglycemic.
Ngokuhlanganiswa ne-insulin, ifomu lama-500 noma lama-850 mg livame ukunqunywa, lelo lithathwa izikhathi ezi-3 ngosuku, umthamo ofanele we-insulin ubalwa ngawodwa, ngokusekelwe ekufundeni kweglucose.
Ezinganeni ezingaphezu kweminyaka eyi-10 ubudala, umuthi ubekwa ngendlela eyi-500 noma eyi-850 mg, ithebhulethi eyi-1 isikhathi ngosuku njenge-monotherapy noma nge-insulin.
Ngemuva kokudla okumelwe kuphele amasonto amabili, umthamo obekiwe ungashintshwa ucatshangelwa ukugcwala kwe-glucose ku-plasma. Umthamo omkhulu wezingane ngu-2000 mg / ngosuku.Uhlukaniswe ngemithamo engu-2-3 ukuze ungabangeli ukukhuphuka kokugaya ukudla.
IGlucophage Long, ngokungafani nezinye izinhlobo zalo mkhiqizo, isetshenziswa ngandlela thile. Uthathwa ebusuku, yingakho ushukela ekuseni uhlala uvamile. Ngenxa yesenzo esibambezelekile, ayilungele ukungena okujwayelekile kwansuku zonke. Uma ngesikhathi sokuqokwa kwayo amasonto e-1-2 umphumela ofiselekile ungatholakali, kunconywa ukushintshela ku-glucophage ejwayelekile.
Ukubuyekezwa
Uma kuqhathaniswa nokubuyekezwa, ukusetshenziswa kwe-Glucofage kuvumela abanesifo sikashukela sohlobo lwesibili ukugcina inkomba ye-glucose ejwayelekile futhi ngasikhathi sinye.
Ngasikhathi sinye, abantu ababeyisebenzisela kuphela ukususa amakhilogremu angeziwe banemibono ye-polar - enye iyayisiza, enye ayenzi, imiphumela yesithathu idlula izinzuzo zomphumela ophumelelayo wokunciphisa isisindo.
Ukuphendula okungalungile kulo muthi kungahle kuhambisane ne-hypersensitivity, ukuba khona kwe-contraindication, kanye nemithamo yokuzilawula - ngaphandle kokubheka izici zomzimba ngamunye, ukungahambisani nezimo zokudla okunempilo.
Okunye ukubuyekezwa ngokusetshenziswa kwe-glucophage:
- UMarina, oneminyaka engama-42. Ngiphuza i-Glucofage eyi-1000 mg njengoba kuchaziwe yi-endocrinologist. Ngosizo lwayo, ama-glucose surges ayagwenywa. Ngalesi sikhathi, isifiso sami sokudla sehlile nokulangazelela kwami amaswidi kwanyamalala. Ekuqaleni kokuphuza amaphilisi, kwaba nomphumela omubi - bekugula, kepha lapho udokotela enciphisa umthamo, konke kwahamba, manje akukho zinkinga ngokuthola.
- UJulia, oneminyaka engama-27. Ukuze kwehliswe isisindo, i-Glucofage yayibekelwe kimi yi-endocrinologist, yize ngingenaso isifo sikashukela, kodwa sanda nje ushukela - 6.9 m / mol. Amavolumu anciphe ngosayizi 2 ngemuva kokudla izinyanga ezintathu. Umphumela ugcine izinyanga eziyisithupha, noma ngemuva kokuyekiswa komuthi. Wabe eseqala ukwelulama futhi.
- USvetlana, oneminyaka engama-32. Ngokukhethekile ngenhloso yokunciphisa isisindo, ngabona i-Glucofage amasonto ama-3, yize ngingenazinkinga noshukela. Isimo besingesihle kakhulu - isifo sohudo senzeka ngezikhathi ezithile, futhi ngangilamba ngaso sonke isikhathi. Ngenxa yalokhu, ngilahla ama-1.5 kg futhi ngawalahla amaphilisi. Ukulahlekelwa isisindo nabo ngokuqinisekile akuyona inketho kimi.
- U-Irina, oneminyaka engama-56. Lapho kutholwa isimo se-prediabetes, kwakumiselwe uGlucophage. Ngosizo lwayo, kungenzeka ukuthi kuncishiswe ushukela kuya kumayunithi angama-5.5. bese ususa amanye ama-9 kg, engijabule kakhulu. Ngabona ukuthi ukuphuza kwakhe kufiphalisa iphango futhi kukuvumela ukuthi udle izingxenye ezincane. Ayikho imiphumela emibi yesikhathi sonke sokuphatha.
Amavidiyo ahlobene
Ngomthelela wamalungiselelo weSiofor neGlucophage emzimbeni wevidiyo:
