I-insulin Humalog eyenziwe ngesiFulentshi nezici zokuphatha kwayo ngepeni yesirinji

Iziguli ezinesifo sikashukela i-mellitus zohlobo lwe-insulin kufanele zifakwe nsuku zonke nge-insulin ukuze zilondoloze impilo ejwayelekile. Lesi sidakamizwa ngezinhlobo ezahlukene. I-Humalog kwipeni yesirinji inezibuyekezo ezinhle. Imiyalo yokusebenzisa leli thuluzi inikezwe esihlokweni.

I-Humalog kwipeni yesirinji: izici

I-Humalog iyi-analogue yeDNA eguquliwe ye-insulin yomuntu. Isici saso esikhulu wukushintsha kwenhlanganisela yama-amino acid kwistakethi le-insulin. Umuthi ulawula i-glucose metabolism. Inomphumela we-anabolic.

I-Humalog Insulin Cartridges

Ngokwazisa kweHumalog, ukugcwala kwe-glycogen, glycerol, fatty acids kuyanda. Ukuhlanganiswa kwamaprotheni nakho kuyathuthukiswa. Ukudla i-Amino acid kuyanda. Lokhu kunciphisa i-ketogenesis, i-gluconeogeneis, i-lipolysis, i-glycogenolysis, i-protein catabolism kanye nokudedelwa kwama-amino acid. IHumalog yi-insulin esebenza ngokufushane.

Into esebenzayo

Isakhi esisebenzayo seHumalog yi-insulin lispro.

I-cartridge eyodwa iqukethe i-100 IU.

Ngaphezu kwalokho kunezakhi ezisizayo: i-glycerol, i-zinc oxide, isisombululo se-sodium hydroxide 10%, isixazululo se-hydrochloric acid 10%, isodium hydrogen phosphate heptahydrate, metacresol, amanzi wokujova.

Abenzi

Iqala insulin inkampani yaseFrance iLilly France. Uphinde wabamba iqhaza ekukhiqizeni inkampani yaseMelika u-Eli Lilly neNkampani. Wenza isidakamizwa no-Eli Lilly Vostok S.A., izwe - iSwitzerland. Kunehhovisi labamele eMoscow. Itholakala e-Presnenskaya embankment, 10.

Ukuhlanganiswa kwe-Insulin Humalog: 25, 50, 100

Le nto isiza ukunciphisa ijubane isenzo se-insulin.

Ekuhlanganeni kwemithi, amanani we-25, 50 no-100 akhombisa ukugcwala kwe-NPH. Lapho le ngxenye ikhona, kulapho isenzo somjovo sisinde. Inzuzo ukuthi banciphisa inani lemijovo yansuku zonke.

Lokhu kwenza lula inqubo yokwelashwa futhi kwenza impilo yomuntu onesifo sikashukela ibe ntofontofo. Okubi ngengxubevange yeHumalog ukuthi ayinikezi i-plasma glucose control enhle. I-NPH imvamisa ukusabela komzimba, ukubonakala kwemiphumela emibi eminingana.

Lezi zinhlobo ze-insulin zilungele abanesifo sikashukela abaneminyaka yobudala, isikhathi sabo sokuphila esifushane, i-senile dementia yaqala. Kwezinye izigaba zeziguli, odokotela bancoma ngokuqinile ukusebenzisa i-Humalog ehlanzekile.

Imiyalo yokusebenzisa

I-Humalog iboniswa ekwelashweni kwesifo sikashukela kubantu abadala nasezinganeni ezidinga i-insulin nsuku zonke ukuze kugcinwe ushukela wegazi ojwayelekile.

Umthamo kanye nemvamisa yokusetshenziswa kunqunywa ngudokotela. Umuthi ungalawulwa nge-intramuscularly, ngokwezifiso noma ngokuxhunywa ngaphakathi emzimbeni. Indlela yokugcina yokusebenzisa ilungele izimo zesibhedlela kuphela.

Ukuphathwa kwe-intravenous ekhaya kuhlotshaniswa nobungozi obuthile. I-humalogue kumakherubhi ifakwa ngaphandle kokusebenzisa isitho sepeni.

Umuthi kufanele usetshenziswe imizuzu eyi-5-15 ngaphambi kokuphathwa noma ngokushesha ngemuva kokudla. Imijovo yenziwa izikhathi ezingama-4-6 ngosuku. Uma isiguli sinqunywe futhi i-insulin isikhathi eside, khona-ke uHumalog ufakwa kathathu ngosuku.

Amapeni wesirinji wesimanje enza lula inqubo yokujova. Ngaphambi kokusetshenziswa, i-cartridge kufanele ibhalwe ezintendeni zezandla. Lokhu kwenziwa ukuze okuqukethwe kube ukufana ngombala nokuvumelana. Musa ukuyixhawula ngamandla. Ngaphandle kwalokho, igwebu lingakheka, elizophazamisa ukwethulwa kwemali.

Okulandelayo kuchaza i-algorithm yokuthi ungayithola kanjani isibhamu ngqo:

• geza izandla kahle ngensipho;
• khetha indawo yomjovo bese uyesula ngotshwala;
• thintisa ipeni lesirinji kanye ne-cartridge efakwe kuyo ngezindlela ezihlukile noma jika izikhathi eziyi-10. Isixazululo kufanele silingane, singabi namibala futhi sibe sobala. Musa ukusebenzisa i-cartridge enamafu, anemibala kancane, noma okuqukethwe okugqinsiwe. Lokhu kuphakamisa ukuthi isidakamizwa sehlile ngenxa yokuthi ibingagcinwanga kahle, noma usuku lokuphelelwa yisikhathi luphelelwe yisikhathi;
• setha umthamo;
• khipha isicoco esivikela ngenaliti;
• lungisa isikhumba;
• faka inaliti ngokuphelele esikhunjeni. Kulokhu, umuntu kufanele aqaphele futhi angangeni emgodini wegazi;
• cindezela inkinobho esibambeni bese uyibamba;
• Lapho i-buzzer ikhala ukuqeda umjovo, linda imizuzwana eyi-10 bese ususa inaliti. Esiqondisweni, umthamo kufanele ube zero;
• khipha igazi elivele ngokugqokwa kukotini. Akunakwenzeka ukwenza i-massage noma ukuthikaza indawo yomjovo ngemuva komjovo;
• beka ithumba lokuvikela kudivayisi.

Ngaphambi kokusebenzisa nangemva kwenqubo, isiguli sidinga ukukala ushukela wegazi nge-glucometer. Ngaphandle kwalokho, kukhona ubungozi be-hypoglycemia.

I-Humalog inokuphikisana okuthile:

• i-hypoglycemia;
• ukungabekezeleli i-insulin lyspro noma ezinye izinto zomuthi.

Uma usebenzisa i-Humalog, kufanele kukhunjulwe ukuthi, ngaphansi kwethonya lezidakamizwa ezithile, isidingo semijovo singashintsha.

Isibonelo, izindlela zokuvimbela inzalo ngomlomo, ama-corticosteroids anethonya le-hyperglycemic. Ngakho-ke, udinga ukuphatha umuthi kumthamo omkhulu. Lapho uthatha amaphilisi we-antidiabetic womlomo, ama-antidepressants, ama-salicylates, ama-ACE inhibitors, ama-beta-blockers, isidingo se-insulin sincishisiwe.

I-Humalog ivunyelwe ukusetshenziswa ngesikhathi sokukhulelwa. Ayikho imiphumela emibi etholakele kwabesifazane abasesikhundleni besebenzisa imijovo yalesi sidakamizwa. Umkhiqizo awuthinti impilo yengane noma entsha. Kepha ngalesi sikhathi, udinga ukuqapha ngokucophelela ukugcwala koshukela egazini.

Kwi-trimester yokuqala, isidingo se-insulin kwesinye isikhathi siyancipha, futhi ku-trimester yesibili neyesithathu iyanda. Ngesikhathi sokuqunjelwa, ukulungiswa komthamo we-insulin nakho kungadingeka.

Ayinayo imingcele echaziwe ye-overdose. Ngemuva kwakho konke, ukugxilwa koshukela we-plasma kungumphumela wokusebenzisana okuyinkimbinkimbi phakathi kwe-insulin, ukutholakala kwe-glucose, kanye ne-metabolism.

Uma ufaka kakhulu, i-hypoglycemia izokwenzeka. Kulesi simo, kuboniswa lezi zimpawu ezilandelayo: ukunganaki, ukubambezela, ukujuluka, ukungaboni kahle, i-tachycardia, ikhanda, ukuhlanza, ukweqisa komhlaba. I-hypoglycemia elinganiselayo ivame ukuqedwa ngokuthatha amaphilisi kashukela, imikhiqizo equkethe ushukela.

Ukuhlaselwa kakhulu kwe-hypoglycemia, okuhambisana nokuphazamiseka kwemizwa, ukoma, kudinga ukuphathwa kwe-glucagon noma kwe-subcutaneous. Uma kungasabeli lutho kulokhu, khona-ke isixazululo esigxile ku-40% kashukela kufanele siphathwe ngokuqondile. Lapho isiguli siphinda siqaphela, sidinga ukondliwa ngokudla kwe-carbohydrate, ngoba kunobungozi be-hypoglycemia ephindaphindwayo.

Uma usebenzisa i-Humalog, imiphumela emibi ingavela:

• ukubonakaliswa komzimba. Zibonwa kakhulu, kepha zibucayi kakhulu. Isiguli singaba nomfutho omfishane wokuphefumula, ukulunywa emzimbeni wonke, ukujuluka, ukushaya kwenhliziyo okujwayelekile, ukwehla komfutho wegazi, ubunzima bokuphefumula. Isimo esibi sisongela impilo;
• hypoglycemia. Umphumela ojwayelekile kakhulu we-hypoglycemic therapy;
• ukusabela komjovo wasendaweni (ukuqubuka, ubomvu, ukulunywa, i-lipodystrophy). Kudlula ngemuva kwezinsuku ezimbalwa, amasonto.

I-Humalog kufanele igcinwe endaweni eyomile neyomnyama ekushiseni kwama-degrees ayi-15 kuya kwangama-25. Umuthi akufanele ufudunyezwe eduze kwesishisi segesi noma kubhethri ngaphambi kokuwusebenzisa. I-cartridge idinga ukubanjwa ezintendeni zezandla.

Ukubuyekezwa

Kunokubuyekezwa okuningi kweHumalog kwipeni yesirinji. Futhi iningi lazo liqondile:

• Natya. Nginesifo sikashukela. Ngisebenzisa uHumalog esibayeni sesirinji. Ukhululekile kakhulu. Ushukela wehlela ngokushesha emazingeni ajwayelekile. Phambilini wayejova i-Actrapid neProtafan. KwaHumalog ngizizwa ngingcono kakhulu futhi ngizethemba ngokwengeziwe. I-Hypoglycemia ayenzeki;
• Olga. Nginesifo sikashukela sonyaka wesibili. Ngalesi sikhathi ngizame ama-insulin ahlukile. Umuthi osebenza isikhathi eside wacosha ngokushesha. Kepha ngomuthi osebenza okwesikhashana isikhathi eside angikwazanga ukunquma. Kubo bonke abaziwayo, uHumalog kwisirinji esisheshayo nguyena owangifanele kunazo zonke. Ngokushesha nangempumelelo kwehlisa ushukela. Ngenxa yesibambo kulula ukusisebenzisa. Ngaphambi kwesingeniso, ngibala amayunithi wesinkwa bese ukhetha umthamo. Senginonyaka owodwa kuHumalog futhi kuze kube manje angizukukushintsha;
• Andrey. Ngonyaka wesihlanu egula isifo sikashukela. Ilokhu ihlukunyezwa ngama-glucose egazini. Muva nje ngidluliselwe kuHumalog. Ngizwa kahle manje, umuthi unikeza isinxephezelo esihle. Ukubuyisa kwayo kuphela intengo ephezulu;
• UMarina Ngihlaselwe yisifo sikashukela kusukela eminyakeni eyishumi. Kuze kube neminyaka eyi-12, wayethatha amaphilisi anciphisa ushukela. Kepha base bema ukungisiza. Ngenxa yalokhu, i-endocrinologist iphakamise ukushintshela ku-insulin Humalog. Bengingafuni ngempela lokhu futhi ngamelana. Kepha lapho amehlo ami eqala ukuwohloka nezinkinga zami zezinso ziqala, ngavuma. Angizisoli ngesinqumo sami. Ukwenza imijovo akuyona eyethusayo. Ushukela manje awukhuphuki ngenhla kwe-10. Ngigculisekile ngomuthi.

Amavidiyo ahlobene

Imiyalo yokusetshenziswa kwe-insulin Humalog kuvidiyo:

Ngakho-ke, uHumalog esibayeni sesirinji umuthi ofanele kubantu abathola isifo sikashukela. Ine-contraindication ezimbalwa nemiphumela emibi. Ngenxa yepeni lesirinji, ukusetha komthamo kanye nokuphathwa kwezidakamizwa kwenziwa lula. Iziguli zinombono omuhle ngalolu hlobo lwe-insulin.