Iziguli eziningi ezinesifo sikashukela, lapho zivakashela udokotela, zimbuza umbuzo wokuthi ngabe iParacetamol ekwelashweni likashukela ingasetshenziswa yini ukwehlisa izinga lokushisa lomzimba.
Lo mbuzo uhlobene neqiniso lokuthi lesi sidakamizwa, ngokuba yi-antipyretic ne-analgesic, sithathwa njengephephe uma siqhathaniswa, ngokwesibonelo, umuthi ojwayelekile njenge-Aspirin.
Njengamanje, i-paracetamol idume kakhulu kangangokuba abenzi bayo bayisebenzisa njengengxenye yenqwaba yezidakamizwa eziklanyelwe ukwelapha ukubanda, ikhanda noma ukuqubuka.
Imvamisa, imiyalo yamalungiselelo, efaka i-paracetamol, futhi esetshenziselwa ukwelapha izifo ezahlukahlukene ezihambisana nomkhuhlane nobuhlungu, ayiqukethe imininingwane yokuthi ingasetshenziswa yini uma isiguli sinesifo sikashukela.
Kuyemukelwa ngokuvamile ukuthi iParacetamol yesifo sikashukela, esetshenziselwa ukwehlisa izinga lokushisa lomzimba kanye nokudambisa izinhlungu, singasetshenziswa ngaphandle kokulimaza umzimba wesiguli. Isifo sikashukela akuyona inkambiso yokusetshenziswa kweParacetamol.
Kodwa-ke, kufanele kukhunjulwe ukuthi ngokusebenzisa isikhathi eside lesi sidakamizwa noma lapho usebenzisa ezinye izidakamizwa kuhlangene neParacetamol, kungenzeka ukulimaza umzimba womuntu ophethwe yisifo sikashukela i-mellitus.
Lapho kukhona isifo sikashukela i-mellitus, umuntu unokwehla kwezindawo zokuzivikela, ngaphezu kwalokho, izinkinga ezinomthelela ekuhlulekeni kwezinso, isibindi, amaseli wezinzwa nenhliziyo kungakhula.
Uma kwenzeka lokhu kwephula umthetho, ukusetshenziswa ngokweqile kwe-Paracetamol kuyingozi kakhulu.
Ngaphezu kwalokho, ushukela uvame ukufakwa kwizidakamizwa ezinezindawo ze-antipyretic ne-analgesic, ezingavusa ukwanda kwenani le-glucose ku-plasma yegazi.
Onke la ma-nuances adinga ukusetshenziswa ngokucophelela kwezidakamizwa ezisetshenziselwa i-anesthetize futhi yehlise izinga lokushisa, ngaphambi kokusebenzisa umuthi kungcono ukuvakashela udokotela wakho futhi uthintane naye ngokusetshenziswa kwomuthi.
Imiphumela emibi yeParacetamol emzimbeni wesifo sikashukela
Ngokuqhubeka kwesifo sikashukela emzimbeni wesiguli, ukuthuthukiswa kwezinkinga eziphazamisa ukusebenza kwesibindi nezinso kuyabonakala.
Ngaphezu kwalokho, ngesikhathi sokuqhubeka kwesifo, ushintsho ekwakhekeni kwegazi luyabonakala.
Ngokusebenzisa okukodwa kweParacetamol, akukho lutho ongalwesaba. Kodwa-ke, esimweni sokusetshenziswa isikhathi eside somuthi emzimbeni wesiguli esine-mellitus yesifo sikashukela, ukuthuthukiswa kwezifo ezahlukahlukene nemiphumela emibi kungenzeka.
Imiphumela emibi evame ukwenzeka ngokusetshenziswa isikhathi eside kweParacetamol yile elandelayo:
- ukulimala okunobuthi kwezicubu zesibindi;
- ukwenzeka kanye nokuqhubekela phambili kokwehluleka kwezinso;
- ukwehla ekwakhekeni kwegazi lenombolo yama-leukocytes namaplatelet;
- ukuthuthukiswa kwezimpawu ze-hypoglycemia emzimbeni wesiguli;
- ukubonakala kobuhlungu esiswini;
- ukubukeka kwezifiso zokuhlanza kanye nohudo.
Amathuba aphezulu wemiphumela emibi lapho usebenzisa i-Paracetamol kwiziguli ezinesifo sikashukela idinga ukusetshenziswa ngokucophelela komuthi. Umuthi kufanele usetshenziswe kuphela ngaphansi kokuqondisa udokotela nangezilinganiso ezijwayelekile zoshukela wegazi.
Uma kunesidingo esiphuthumayo, umuthi ungadakwa amahlandla ama-1-2 ngaphandle kokwesaba ukwephulwa okukhulu ekusebenzeni komzimba womuntu ohlushwa isifo sikashukela.
Ukwakheka nezakhiwo zomuthi Paracetamol nefomu lokukhululwa
Isithako esisebenzayo seParacetamol yikhompiyutha esebenzayo yegama elifanayo.
Ithebhulethi elilodwa liqukethe i-200 mg yokusebenza okusebenzayo.
Ngaphezu kwento esebenza ngayo, umuthi uqukethe ezinye izakhi ezidlala indima yokusiza.
Izici ezisizayo zomuthi yilezi:
- IGelatin
- Isitashi samazambane.
- I-Stearic acid.
- Ushukela wobisi - i-lactose.
Izibhebhe zomuthi ziyisicaba-cylindrical nge-bevel futhi nengozi ifakwa ebusweni.
Izibhebhe ngopende omhlophe noma ukhilimu omhlophe nge-tint kirimu. Umuthi ungoweqembu lezidakamizwa ezingezona ze-analgesic ezingezona izidakamizwa.
Isenzo se-paracetamol sisuselwa empahleni yengxenye esebenzayo yesidakamizwa ukuvimba ukwakheka kwama-prostaglandins, okwenzeka ngenxa yokuvinjwa kwe-cycloo oxygenase 1 ne-cycloo oxygenase 2. Lesi senzo somuthi sivimba izikhungo zobuhlungu kanye nokuqina komzimba.
I-Paracetamol ishesha futhi icishe ifakwe ngokuphelele emgomeni wesisu. Into esebenzayo yesidakamizwa iyakwazi ukubopha kumaphrotheni e-plasma. Izinga lokubopha lifinyelela ku-15%.
IParacetamol iyakwazi ukungena ekuvinjelweni kwegazi-ingqondo. Cishe u-1% womthamo othathwe uyakwazi ukudlula ubisi lwebele lapho uncelisa ingane ibele.
I-Half-life yesidakamizwa emzimbeni ivela kwihora elilodwa kuya kwele-4. Emzimbeni, i-paracetamol iba nezinguquko ze-metabolic ezicutshini zesibindi futhi ikhishwa yizinso ngomchamo.
Umthamo oyinhloko wesidakamizwa udedelwa esigulini ngesimo se-glucuronides ne-conjugates ye-sulfonated, futhi cishe yi-5% kuphela yomthamo wezidakamizwa owethelwe emzimbeni othululwayo ungashintshiwe emchameni.
Imiyalo yokusebenzisa umuthi
Isibonakaliso sokusetshenziswa kwalo muthi ubukhona bekhanda ekhanda esigulini, kufaka phakathi izinhlungu ngesikhathi se-migraine, izinyo, izinhlungu ngesikhathi sokukhula kwe-neuralgia. Umuthi usetshenziswa futhi ukudambisa izinhlungu ngesikhathi sokulimala nokushiswa.
Umuthi uyanconywa ukuthi usetshenziselwe ukwehlisa izinga lokushisa lomzimba ngesikhathi sokukhula komkhuhlane noma umkhuhlane kushukela.
I-Paracetamol inezindlela eziningi zokuphikisana nokusetshenziswa komuthi.
I-contraindication esemqoka yilena elandelayo:
- isiguli sinokuzwela okwengeziwe kwizakhi zomuthi;
- ukuba khona kwesiguli sokwephulwa kokusebenza kwezicubu zezinso nezinso;
- izingane ezingaphansi kweminyaka emithathu.
Ukuqapha lapho usebenzisa i-paracetamol kufanele kukhonjiswe uma isiguli sine-benign hyperbilirubinemia, i-hepatitis yegciwane, ukulimala kotshwala kwezicubu zesibindi. Ukuba khona kokusweleka kwe-glucose-6-phosphate dehydrogenase emzimbeni futhi kudinga ukuqaphela lapho usebenzisa umuthi.
Umuthi awuvunyelwe ukusetshenziselwa ukwelashwa kwezifo esimweni sokwelashwa okuyinkimbinkimbi ngenkathi usebenzisa eminye imishanguzo, efaka i-paracetamol njengenye yezakhi.
Lapho usebenzisa iParacetamol ekwelapheni umkhuhlane, umthamo wezidakamizwa uqhamuka ku-0,5 uye ku-1 gram. Umuthi kufanele uphuzwe emahoreni angama-1-2 ngemuva kokudla. Ukuthatha umuthi kufanele kuhambisane nokusetshenziswa kwenani elikhulu lamanzi njengesiphuzo.
Isilinganiso esiphezulu somuthi akufanele singeqi amagremu ama-4 ngosuku.
Isikhathi sokuphakathi kwemithamo yomuthi kufanele okungenani sibe amahora ama-4.
Kufanele kukhunjulwe ukuthi akufanele uthathe amaphilisi angaphezu kwama-8 usuku lonke.
Uma umuntu ogulayo eba nokuhlukumezeka esibindini nasezinso, isilinganiso somuthi osetshenzisiwe kufanele sincishiswe, futhi isikhathi phakathi kwemithamo yomuthi siyakhuphuka.
Ukubuyekezwa mayelana nomuthi, izindleko zawo kanye nama-analogues
I-Paracetamol umuthi odume kakhulu osetshenziselwa ukubulala izinzwa kanye nomkhuhlane ophansi. Ngokuya kokubuyekezwa okutholakele, umuthi umuthi osebenza ngempumelelo ongabhekana kalula nomsebenzi wawo.
IParacetamol kufanele igcinwe endaweni evikelwe ukukhanya kwelanga, engatholakali ezinganeni.
Endaweni yokugcina umuthi, izinga lokushisa lomoya akufanele libe ngaphezulu kwama-25 degrees Celsius.
Impilo yeshelf umuthi iminyaka emi-3. Ekupheleni kwalesi sikhathi, ukusetshenziswa komuthi akuvunyelwe. Umuthi ungathengwa kunoma iyiphi ikhemisi ngaphandle kwemithi kadokotela.
Izindleko zeParacetamol ezibhebheni eziseRussia zingaphakathi kwama-ruble ayi-15.
Ngaphezu kwalesi sidakamizwa, ungasisebenzisa ukuphatha izichasiso zayo, ngokwesibonelo,
- Acetylsalicylic acid;
- I-Citramon;
- Coficil;
- Askofen;
- I-Baralgin;
- I-analgin nabanye.
- IFavex ayinashukela (kumkhuhlane, umkhuhlane kanye nemfiva ephezulu).
Kufanele kukhunjulwe ukuthi ukusetshenziswa kweParacetamol noma i-analogues yayo kudinga ukwelulekwa ngodokotela. Ividiyo ekulesi sihloko izachaza ukuthi umkhuhlane ungalashwa kanjani isifo sikashukela.
