Kuze kube manje, osokhemisi sebelungele ukuhlinzeka ngethoni yezindlela zokwelapha zokwelapha isifo ngasinye. Kepha kuhlale kunzima ukunquma ukuthi yikuphi okuzoba yisigamu esifanele kunazo zonke esigulini.
Imvamisa ukukhetha phakathi kwezindlela ezicishe zilingane, isibonelo, i-Berlition noma i-Oktolipen.
Ukunquma izinzuzo nobubi ngamunye wabo, kufanele ubacabangele ngemininingwane eminingi.
Isenzo se-Pharmacological
I-Berlition ingeyeqembu le-antioxidant ne-hepatoprotective. Umuthi unezakhiwo ze-hypoglycemic kanye ne-lipid-okwehlisa, umphumela wazo osuselwa ekunciphiseni kokugxilisa i-glucose, kanye nokuqedwa kwama-lipids okweqile egazini lomuntu.
Isithako esikhulu esisebenzayo se-Berlition yi-thioctic acid, etholakala cishe kuzo zonke izitho zomzimba. Kodwa-ke, inani layo elikhulu kunazo zonke lisenhliziyweni, izinso nesibindi.
Izibhebhe ze-Berlition
I-Thioctic acid iyi-antioxidant enamandla esiza ukunciphisa imiphumela ye-pathogenic yama-toxin ahlukahlukene, kanye nezinye izinhlanganisela ezinobuthi nezinsimbi ezisindayo. Izici zakhe ezinhle azipheli lapho, uyakwazi ukuvikela isibindi ezintweni zangaphandle ezingezinhle, futhi anikele ekwenzeni umsebenzi wawo ube ngcono.
I-Lipoic acid inomphumela omuhle ezinqubweni ze-carbohydrate kanye ne-lipid metabolic, ibenza buthakathaka, futhi isiza ukwehlisa isisindo esiphelele futhi inciphisa noshukela wegazi. Kuyaziwa ukuthi umphumela we-biochemical of thioctic acid yi-analogue yamavithamini we-B.
Ukuqhathaniswa kwe-thioctic acid ngamavithamini we-B kuhlotshaniswa neqiniso lokuthi linezinto ezilandelayo ezisebenzayo:
- ivuselela i-metabolism ye-cholesterol;
- kuthuthukisa ukuqalwa kabusha, kanye nokususwa ngokuqondile kwama-atherosselotic plaque emzimbeni, futhi kungavimbela ukukhula kwabo.
I-Oktolipen yi-ejenti ye-metabolic eyi-antioxidant ye-endo native.
Isenzo esiyinhloko somuthi sibhekwa njengokubopha ama-free radicals, futhi into esemqoka esebenzayo yi-thioctic acid. Ngaphezu kwalokho, yehlisa izinga le-glucose egazini, isiza ukunqoba ukumelana ne-insulin futhi inyusa amazinga e-glycogen esibindini. I-Lipoid acid ngokwejwayelekile i-carbohydrate kanye ne-lipid metabolism, futhi futhi isebenze i-cholesterol metabolism.
Izibhebhe ze-Octolipen
I-Oktolipen inemiphumela elandelayo:
- hypocholesterolemic;
- i-hypoglycemic;
- ukwehliswa kwe-lipid;
- hepatoprotective.
Izinkomba kanye ne-contraindication
I-Berlition inemiphumela eminingi emihle ethuthukisa isimo esivamile sesiguli.
Umuthi unconywa ukuthi usetshenziswe ngabantu abanemibandela elandelayo:
- i-osteochondrosis yanoma yikuphi ukwenziwa kwasendaweni;
- i-hepatitis;
- i-cirrhosis;
- ubuthi obungamahlalakhona nosawoti wezinsimbi ezisindayo;
- isifo sikashukela se-polyneuropathy;
- ubuthi enobuthi obuhlukahlukene.
I-Oktolipen ikhonjisiwe ukusetshenziswa emacaleni alandelayo:
- i-polyneuropathy yotshwala;
- isifo sikashukela polyneuropathy.
Ngaphandle kokuthi iBerlition inezinkomba eziningi, kunezimo lapho ukwamukelwa kwayo kuphikiswa. Lokhu kufaka phakathi:
- isigaba seminyaka engaphansi kweminyaka eyi-18;
- ukungabekezelelani kwe-lactose;
- hypersensitivity to thioctic acid, kanye nezinye izingxenye ze-Berlition;
- isikhathi sokukhulelwa;
- galactosemia;
- ukucaphuka.
Umuthi i-Oktolipen uvunyelwe ku-:
- ukukhulelwa
- ngaphansi kweminyaka eyi-18;
- i-hypersensitivity ku-lipoid acid noma ezinye izinto zomuthi;
- ngesikhathi sokubeletha.
Umthamo kanye ne-overdose
I-Berlition kumele ithathwe ngomlomo ku-dosage evame ukusukela kuma-300 kuya kuma-600 milligrams izikhathi ezi-1-2 ngosuku.
Ezimweni ezinobunzima be-polyneuropathy, ama-milligram angama-300-600 aphathwa ngokuhlinzwa ekuqaleni kokwelashwa, okuhambelana namamililitha ayi-12- 24 ngosuku.
Imijovo enjalo kumele iqhubeke izinsuku eziyi-15-30. Ngokuzayo, ukushintshela kancane kancane ekwelashweni kwesondlo, ukwelashwa nge-Berlition kunqunywa ngendlela yokukhishwa kwethebhulethi yamamiligrama angama-300 kanye ngosuku.
Ukuze ulungiselele isixazululo sokungenela, kuyadingeka ukusula ama-ampoules angama-1-2 we-Berlition 300 U ngamamililitha angama-250 wesisombululo se-sodium chloride, ngemuva kwalokho i-ejenti kufanele iphathwe ngokuhlinzwa imizuzu engama-30.
Kumele kukhunjulwe ukuthi into esebenzayo yalesi sidakamizwa i-photosensitive, yingakho isixazululo kufanele silungiselelwe ngokushesha ngaphambi kokusetshenziswa, futhi impilo yayo eshalofini akufanele ibe ngaphezulu kwamahora ayi-6, kepha lokhu kungaphansi kokulondolozwa endaweni emnyama.
Izimpawu eziphambili zokweqisa komuthi i-Berlition yilezi zimpawu ezilandelayo:
- isicanucanu
- ikhanda elinzima;
- ukuhlanza
- ukungazi kahle;
- ukuphazamiseka kwengqondo
- izindlela zokuhlaselwa okubanzi;
- ukuthuthukiswa kwe-lactic acidosis.
Kubalulekile ukungabuphuzi utshwala uma uthatha umthamo omkhulu (kusuka ku-10 kuye ku-40 amagremu) we-thioctic acid, ngoba kulokhu kungenzeka ukudakwa kakhulu komzimba, ngenxa yalokho kungaba nomphumela obulalayo.
Ngenxa yobuthi, imiphumela elandelayo elandelayo yenzeka:
- ukwethuka
- i-hypoglycemia;
- Igazi le-ICE;
- i-rhabdomyolysis;
- ukwehluleka kwezitho eziningi;
- amathambo emashi.
Uma usola ukudakwa, ukulaliswa esibhedlela ngokushesha kuyadingeka ukufeza izinqubo ezijwayelekile, ezibandakanya: ukushaqeka kwesisu, ukudla kwekhabhoni ocushiwe, ukuqashelwa kokufakelwa kokuhlanza.
I-Okolipen imvamisa iphuzwa ngomlomo esiswini esingenalutho, lokhu kwenziwa imizuzu engama-30 ngaphambi kokudla. Akunakwenzeka ukuthi uchithe ubuqotho bethebhulethi nganoma iyiphi indlela, kufanele ihlanzwe phansi ngevolumu eyanele ye-ketshezi.
Umthamo, njengokomthetho, ungamamayela angama-600 kumthamo owodwa. Isikhathi esiphezulu sokusebenzisa siyizinyanga ezi-3. Ngawodwana, ukwelulwa kwesikhathi sokwelashwa kungenzeka.
Ezimweni ezimbi kakhulu, isixazululo somjovo we-intravenous sinqunywe ekuqaleni kokwelashwa. Ngemuva kwamasonto angama-2-4, isiguli sidluliselwa kuma-ejenti omlomo.
Uma kwenzeka kwe-overdose ye-Octopylene, kuvela izimpawu ezilandelayo:
- isicanucanu
- ikhanda
- ukuhlanza
Imiphumela emibi
I-Berlition ingadala imiphumela emibi ehlukahlukene, kepha, kuyaphawuleka ukuthi ukubonakaliswa kwabo akuvamile. Bangaba kanjena:
- isicanucanu kanye nesifiso sokuhlala njalo sokuhlanza;
- ukusikwa kwemisipha;
- ukuhlanza
- umbono ophindwe kabili
- izinzwa zobuhlungu kanye nokuvutha kwemizwa endaweni yomjovo noma ukumametwa;
- ushintsho lokunambitha;
- i-thrombophlebitis;
- imishayo ye-hemorrhagic;
- iphoyinti lokwenza okokusebenza kwasendaweni;
- ukungahambi kahle esikhunjeni: ukuqubuka, i-urticaria, ukulunywa;
- kwehlise izinga lokuhlaselwa kwe-glucose egazini, ngenxa yalokho imiphumela emibi ikhula: ikhanda, ukujuluka kokukhula, isiyezi;
- ukuthuthukiswa kokuthuthumela kwe-anaphylactic. Lesi sibonakaliso siyabonakala kubantu abajwayele ukubonakaliswa yi-allergic;
- usizi ekhanda. Lesi sibonakaliso siziveza ngenxa yengcindezi engaphezulu yangaphakathi nokuphatha okusheshayo;
- umsebenzi wokuphefumula okhubazekile;
- ukopha okuthe xaxa.
Izenzo ezingathandeki ze-Oktolipen zingaba:
- Izimpawu ze-dyspepsia (ikakhulukazi ukugabha, ukushisa kwenhliziyo, isicanucanu);
- ukubonakaliswa kwe-allergic (ukushaqeka kwe-anaphylactic, ukulunywa, i-urticaria);
- izimpawu ze-hypoglycemia.
Yini engcono?
Umuthi oyinhloko osebenzayo (i-thioctic acid) uyefana kulezo zidakamizwa zombili ezidingidwayo.
Umehluko wabo omkhulu usezweni lendabuko. Abanye bakholelwa ukuthi uma umkhiqizo uvela kwamanye amazwe, khona-ke kufanele ukuthi usebenze kakhudlwana.
Kepha, ngokusho kochwepheshe, akusekho mpendulo eqinisekile yokuthi ngabe iJalimane Berlition le-Okolipen lasekhaya lingcono yini. Ukubuyekezwa kweziguli kukhuluma ngamathuba okugcina ngaphezulu kwawangaphambili, ikakhulukazi, ngenqubomgomo yezindleko.
Amavidiyo ahlobene
Mayelana nezinzuzo ze-alpha-lipoic (thioctic) acid sikashukela kuvidiyo:
I-Berlition ne-Oktolipen sekuyisikhathi eside siqhathaniswa, kepha akekho umuntu osafike esiphethweni esingaqondakali sokuthi iyiphi ikhambi esasebenza kakhulu. Ukwakheka nezinkomba zokusetshenziswa ziyefana, okungenakushiwo ngezindleko.
Imiphumela engathandeki ayivamile ku-Berlition. Contraindication inenani elifanayo. Ukusebenza okusebenzayo kuphela okuzobonisa ukuthi yisiphi isidakamizwa esifanelekile ecaleni ngalinye.
