Umuthi i-Fraxiparin: amafomu wokukhishwa nentengo

Ama-hepatins aphansi (LMWH) aphansi ayisigaba sezidakamizwa ze-anticoagulant ezisetshenziselwa ukuvimba nokwelapha izinkinga ze-thromboembolic.

Uhla lwezicelo lubanzi impela, luhlanganisa iphrofayili yokuhlinzwa neyokwelapha, kanye nomuthi ophuthumayo.

Ngokungafani neyandulelayo yayo, i-Heparin, i-LMWH isho umsebenzi we-pharmacological, iphephile futhi ilawulwa kakhudlwana, ingahanjiswa ngokungaxutshiwe noma ngokuxhunywa ngokungemthetho.

Namuhla, izizukulwane eziningana zalezi zidakamizwa zivezwa emakethe, ezihlinzekelwa njalo ngemithi emisha. Le ndatshana izogxila kwiFraxiparin, intengo nekhwalithi yazo yokwanelisa ngokugcwele izidingo zodokotela neziguli.

Izinkomba

Into esebenzayo yeFraxiparin yi-calcium nadroparin, ekhonjiswe kulezi zimo ezilandelayo zomtholampilo:

• ukuvimbela i-thrombosis ezigulini ezinephrofayili yokuhlinzwa;
• ukwelashwa kwe-pulmonary embolism;
• ukwelashwa kwe-thrombophlebitis yemisuka ehlukahlukene;
• ukuvimbela ukwanda kwegazi ngesikhathi se-hemodialysis;
• ekwelapheni i-acute coronary syndrome (isifo senhliziyo).

Kubalulekile ukuqaphela ukuthi i-Fraxiparin isetshenziswa ikakhulukazi esibhedlela ngaphansi kokuqondisa udokotela. Ngaphambi kokuqokwa, kufanele kwenziwe uchungechunge lwezifundo zasemtholampilo nezelebhu, ikakhulukazi i-coagulogram.

Contraindication

Awukho umuthi olungele zonke iziguli.

Ngaphambi kokusebenzisa, kufanele ufunde ngokucophelela imiyalo bese unquma ukuthi unayo yini le mibiko elandelayo:

• ukungahambi kahle komzimba kuma-nadroparin calcium noma izingxenye ezisizayo eziyingxenye yesisombululo;
• i-thrombocytopenia;
• ukopha okusebenzayo noma ingozi eyengeziwe yokukhula kwayo;
• ukulimala kwengqondo ebuhlungu;
• ukukhulelwa nokuqunjelwa;
• ukwehluleka okunzima kwezinso;
• izingane ezingaphansi kweminyaka engu-18 (ukuphikiswa okuhlobene).

Ngokungafani neHeparin, ene-antidote yemvelo - I-Protamine sulfate, i-LMWH ayenzi.

Khipha ifomu

I-Fraxiparin iyatholakala njengesixazululo sokuphathwa kwe-subcutaneous noma intravenous. Kutholakala kumasirinji avinjelwe alahliweyo nge cap yokuvikela, efakwe ngokuphephile izingcezu eziyi-10 kwiphakeji.

Isixazululo sokuphatha subcutaneous of Fraxiparin

Imvamisa ifakwa kancane kancane, ngoba lokhu isirinji lisuswa kulolwitho bese ikhoseli lisuswa. Indawo yomjovo (isifunda somoya) yelashwa kathathu nge-antiseptic.

Isibaya esikhunjeni sakhiwa ngeminwe yesandla sobunxele, inaliti ifakwa ngokuqinile esikhunjeni saso sonke isikhumba. Isirinji isusiwe, ayilungele ukusetshenziswa kabusha.

Umkhiqizi

Le nkampani ibisemakethe iminyaka engaphezu kuka-160, ngokusho kuka-2017, iphakathi kwabaholi bomhlaba abayishumi ekwakhiweni kwemithi, imishini yezokwelapha neyelebhu.

Izinkampani zaseFrance iSanofi-aventis ne-Glaxosmithkline zibonisa imithamo eyahlukahlukene ye-calcium nadroparin, ebuye ibe ngaphansi kwegama lokuhweba elithi Fraxiparin.

Kulokhu, umuthi ungowokujwayelekile (uthenge ilungelo lokukhiqiza kwa-Aspen). E-Ukraine, iNadroparin-Farmeks iyatholakala ukuthi iyathengiswa, ekhiqizwa amaqembu enkampani iPremex.

Ukupakisha

Kutholakala kuma-syringes alahlwayo we-0.3, 0.4, 0.6 no-0.8 ml, izingcezu eziyi-10 kwiphakeji eyodwa.

Umthamo wezidakamizwa

0.3 ml

Umthamo uncike ekuhlakazweni kwento esebenzayo - i-calcium nadroparin, ekalwa amayunithi aphesheya.

I-1 ml yeFraxiparin iqukethe i-9500 IU yesakhi esisebenzayo.

Ngakho-ke, ku-0.3 ml kuzoba ngu-2850ME. Kuleli nani, umuthi ukhonjiswa ezigulini ezinesisindo sazo esingadluli kuma-45 kg.

0.4 ml

Kuqukethe i-3800 IU ye-nadroparin calcium, kukhonjiswa ezigulini ezinesisindo esisuka ku-50 kuye ku-55 kg.

0.6 ml

Inesithako esisebenzayo se-5700ME, esilungele iziguli ezisuka ku-60 ziye ku-69 kg.

Izindleko

Intengo yeFraxiparin incike kumthamo nomenzi. Akusho ukuthi umuthi womkhiqizo ubiza kakhulu kunowenziwe ojwayelekile.

Intengo yeFraxiparin, kuya ngomthamo:

Amanani aphakathi, alethwa ngonyaka we-2017. Kungehluka esifundeni nasekhemisi.

Amavidiyo ahlobene

Mayelana nenkathi ye-thrombophlebitis kusifo sikashukela kuvidiyo:

Ngakho-ke, i-Fraxiparin iyisidakamizwa esisemqoka ekwelapheni nasekuvimbeleni i-thrombosis. Phakathi kwezinzuzo kukhona izinhlobonhlobo zemithamo etholakalayo, ukuphepha nezindleko ezifanele.