I-Glucobai ekwehlisa ushukela: imiyalo yokusebenzisa, intengo, ukubuyekezwa, ama-analogues

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Isifo sikashukela yisifo esihlobana nobunzima be-metabolic emzimbeni. Kulokhu, kubonakaliswa iqiniso lokuthi iphesenti likashukela osegazini lidlula inani elivumelekile.

Namuhla, kunezidakamizwa eziningi ezisebenzayo ezingavimbela ukugaya nokufaka ama-carbohydrate emathunjini amancane.

Njengomphumela wokuthatha imali enjalo, ukwanda kwe-glucose ngemuva kokudla ukudla, okuqukethe ama-carbohydrate wesabelo sebhubesi, kuncishiswa kakhulu. Omunye wale mithi iGlucobay.

Njengomthetho, kunqunyelwe kulabo bantu abahlushwa i-insulin-ezimele yesifo sikashukela. Thatha kuphela ezimweni lapho ushintsho olukhulu lwendlela yokuphila nokudla okungekuhle, kanye nokusetshenziswa kwama-hypoglycemic agents kunganiki umphumela ofanele futhi kulawule ukuthuthukiswa kwesifo.

Ukwakheka

Umuthi ekwakhekeni kwawo uqukethe into esebenzayo ebizwa nge-acarbose. Kuyinto i-oligosaccharide ebonakala ngemuva kokuvutshelwa okuvela kwi-microorganism Actinoplanes utahensis.

Izibhebhe ze-Glucobay

Umuthi wenziwa ezibhebheni. Umthamo uvezwa ku-50 mg no-100 mg. Izinto ezingeziwe yi-anhydrous colloidal silicon dioxide, isitashi sommbila ne-microcrystalline cellulose.

Izinkomba zokusetshenziswa

Kunqunyelwe ukuqeda izimpawu zesifo sikashukela sohlobo 2.

Ukuze i-Glucobai ibe nomphumela omuhle kakhulu emzimbeni, kufanele ifakwe ngokudla okukhethekile.

Futhi, odokotela abaningi bayasinikeza ukuvikela lesi sifo esingesihle ezigulini ezinombuso okuthiwa yi-prediabetes state, ngokuhambisana nokudla okufanele kanye nokwenyuka komzimba okwandayo.

Contraindication

Imiyalo yokusebenzisa umuthi i-Glucobai iqukethe lonke ulwazi oludingekayo ngakho, kepha ungathola inani, ujwayele ukubuyekezwa kanye nezikhalazo kwi-Intanethi.

Njengayo eminye imithi efanayo, ine-contraindication. Lokhu kufaka phakathi:

  • i-pathologies yamathumbu esibi;
  • ukuphazamiseka kokugaya ukudla kanye nokudla;
  • ukuzwela kwento esebenzayo yesidakamizwa;
  • ngaphansi kweminyaka eyishumi nesishiyagalombili ubudala;
  • imibandela ephelezelwa ukuthopha;
  • ukukhulelwa nokuqunjelwa;
  • ukwephulwa kokusebenza okujwayelekile kohlelo lwe-excretory.

Ngokuqapha, kufanele kuthathwe izifo kanye nezimo ezinjengokuthi:

  • umkhuhlane ophakeme;
  • izifo ezithathelwanayo ezinzima;
  • ukulimala kwamathambo ohlelo lwe-musculoskeletal, joints and ligaments;
  • ukuhlinzwa kwakamuva.

Ngokusebenzisa leli thuluzi isikhathi eside, kungenzeka ukwanda kwezinga lama-enzyme “wesibindi”, okuvela ngaphandle kwezimpawu ezibonakalayo nezifihliwe.

Ngakho-ke, phakathi konyaka wokwelashwa nalesi sidakamizwa, kuyadingeka ukulawula izinga lalezi zinto. Ngemuva kokuyekiswa komuthi i-Glucobay, ukusebenza kwabo kusheshe kubuyela kokujwayelekile.

Njengoba kushiwo ngaphambili, akunconyelwe ukuthi abesifazane bayisebenzise esimeni esijabulisayo nangesikhathi sokuqunjelwa. Uma ungakunaki lokhu ku-contraindication, khona-ke ungahlangana ne-pathologies engathi sína esibelethweni nasenganeni.

Awukwazi ukuqala ukuthatha umuthi ngokwakho. Udokotela oholayo kuphela ongakunquma ngemuva kokuthola isifo esibizwa ngokuthi isifo sikashukela i-mellitus.

Indlela yokusebenzisa nomthamo

Ngokuqondene nokudla kwamathebulethi eGlucobay, ukusebenza kahle kakhulu kungatholwa uma uwathatha ngaphambi kokudla ngendlela efile, ngaphandle kokuhlafuna.

Phuza ithebhulethi ngenani elincane lamanzi okuphuza ahlanzekile. Musa ukuphuza obunye boketshezi, ikakhulukazi obuqukethe ushukela ekwakhiweni. Uma ufisa, ungakuhlafuna ngengxenye yokuqala yokudla.

Ngokuqondene nomthamo, kunqunywa kuphela ngudokotela oya kuye. Kuyo yonke indawo, kukhethwe imithamo yayo. Lokhu kungenxa yokuthi ukusebenza nokubekezelelwa kwento esebenzayo ngesiguli yehlukile kuwo wonke umuntu. IGlucobai isetshenziselwa ukwelashwa okuxubile okuhambisana nokudla okukhethekile ezigulini ezinesifo sikashukela sohlobo 2.

Ngokusho kwemiyalo yokusebenzisa umuthi i-Glucobay, umthamo owodwa wokuqala yithebhulethi elilodwa (50 mg). Umthamo wansuku zonke - ithebhulethi kathathu ngosuku. Okulandelayo, kufanele ukhuphule umthamo, manje okufanele ube ngamathebulethi ama-50 mg kathathu ngosuku.
Kwezinye izimo, umthamo ungakhuphuka ube ngu-200 mg kaningana ngosuku. Kubalulekile ukukhumbula ukuthi udinga ukwandisa inani lomuthi osetshenziswa kuphela ikhefu lezinyanga ezimbili, kungaphansi.

Uma isiguli sithatha i-Glucobai, naphezu kokubambelela ngokuqinile ekudleni okunqunyiwe, isifo sohudo kanye ne-flatulence sanda kuphela, khona-ke ukwanda okulandelayo komthamo kumele kumiswe ngokushesha noma kuncishiswe nje.

Umthamo ophakathi nsuku zonke ungama-300 mg ngosuku.

Ezinganeni ezingaphansi kweminyaka eyishumi nesishiyagalombili ubudala, ukwelashwa ne-Glucobai kuyaphulwa.

Imiphumela emibi

Ngokusho kwemiyalo yokusebenzisa umuthi i-Glucobay, intengo yayo etholakala kunoma iyiphi ikhemisi, inemiphumela emibi efana nale:

  • ukunqwabelana kwamagesi emathunjini;
  • isifo sohudo
  • ubuhlungu obungabekezeleleki esiswini;
  • ukuqunjelwa;
  • komzimba
  • ukudumba;
  • ukuvinjwa kwamathumbu;
  • jaundice
  • umsebenzi owengeziwe wama-transaminase “wesibindi”.

Ukweqisa

Uma umthamo owandayo walesi sidakamizwa utholwa kanye nokudla noma iziphuzo eziqukethe ama-carbohydrate, khona-ke i-overdose ingabonakala njengokuqhakaza nohudo. Kulokhu, ukudla neziphuzo eziqukethe ama-carbohydrate amaningi kufanele kungafakwa ngokushesha ekudleni. Lapho uthatha umthamo omuhle walo muthi ngaphandle kokubheka ukudla, ukuthuthukiswa kwezimpawu ezingenhla akubonwa.

Ukuxhumana nezinye izidakamizwa

Kubaluleke kakhulu ukuthi uqaphe ngokucophelela ukudla okudla ngesikhathi sokwelashwa nge-Glucobay.

Uma usebenzisa imikhiqizo yokudla enamazinga aphezulu kashukela ngasikhathi sinye nomuthi, ungathola ubuhlungu obungemnandi besisu, obuhambisana nesifo sohudo.

Le nto ichazwa ukuvutshelwa okuphezulu kwama-carbohydrate emathunjini amakhulu. I-Cholestyramine, i-adsorbents kanye namalungiselelo aqukethe ama-enzyme okusheshisa ukugaya kungathinta umphumela wamathebulethi weGlucobai.

Kepha ngokuhlanganiswa nezinto ezifana ne-dimethicone ne-simethicone, akukho ukusabela okungekuhle noma okungathandeki kubonwa. Kuyaziwa ukuthi isidakamizwa sishintsha kakhulu i-bioavailability ye-digoxin. Kodwa okususelwa ku-sulfonylurea, i-insulin, i-metformin kukhulisa umphumela we-hypoglycemic wento esebenzayo esebenzayo.

Kubalulekile ukuqaphela ukuthi ama-ejenti abangela i-hyperglycemia (i-diuretics, ama-steroid ama-hormone, i-phenothiazine, ama-estrogens, ama-contracepiment, isoniazid, i-nicotinic acid, ama-hormone e-thyroid, ama-calcium channel blockers) anciphisa ukusebenza kwe-acarbose. Njengomphumela walokhu, ukuthuthukiswa okungathandeki kokubola kweshukela kungenzeka.

Ngesikhathi sokulashwa ngomuthi, ukusetshenziswa kwekhabhoni ocushiwe namanye ama-adsorbents amathumbu afanayo anganciphisa ukusebenza kwawo kufanele kuqedwe ngokuphelele.

Imiyalo yokusebenzisa

Abanye abantu bayisebenzisa ukulwa namaphawundi angeziwe. Ngaphandle kwalokhu, iGlucobai akuyona indlela yokunciphisa umzimba.

IGlucobai umuthi okhethekile onqunyelwe isifo sikashukela ikakhulukazi.

Kubalulekile ukuqaphela ukuthi akunakuthi noma kunjalo kunconyelwe ukuhlanganisa nezinye izidakamizwa, ngaphandle kokuthi kwaziwa ngokusebenzisana kwabo nalaba abasondelayo.

Ukusebenza kwalesi sidakamizwa kuyaqondakala impela: ihlose ukunciphisa ukumuncwa kwama-carbohydrate, kungavumeli ushukela ukhuphuke egazini. Ngamanye amagama, ivimba ingxenye ethile yama-kilojoule atholakala ekudleni okune-carbohydrate eningi.

Umuthi obizwa nge-acarbose udabula amakhompiyutha ayinkimbinkimbi kashukela abe ushukela. Ngaphezu kwalokho, abokugcina babo balahlekelwa yikhono lokungenwa amathumbu futhi bangangeni egazini. Kungokusho kwalokhu ukuthi isenzo salezi zibhebhe sisuselwa: ngokuzisebenzisa ngokudla okuqukethe ama-carbohydrate, amathuba wokufaka amakhilogremu angeziwe emzimbeni angaqedwa ngokuphelele.

Mayelana neGlucobai, ukulahleka kwesisindo kukhombisa ukuthi umuthi uyasebenza ngempela.

Ngaphezu kwalokho, kulabo bantu abamesabayo ukulimaza imizimba yabo futhi bawele enkingeni evela emazingeni kashukela, umenzi unikeza isiqinisekiso sokuthi into esebenzayo yesidakamizwa i-Glucobai ebizwa nge-acarbose ayikwazi ukwehlisa izinga likashukela lifike ezingeni elibucayi.

Futhi, akakwazi ukuvusa izimo ze-hypoglycemic.

Thatha umuthi kuphela ngesikhathi sokudla. Abasekeli bokudla okulula badinga ukuqikelela ngokucophelela ukuthi ngesikhathi sokudla okuncane ekwakhiweni kwawo kukhona ama-carbohydrate ambalwa ngangokunokwenzeka.

Intengo nezimpawu

Kwisidakamizwa i-Acarbose (Glucobai), intengo ayiphansi - kusuka kuma-ruble angama-500 kuye kwangama-850 ngephakeji ngalinye. Njengoba abantu abaningi bengakwazi ukukhokhela lesi sidakamizwa, kungenzeka ukuthenga ama-analogues ashibhile ngamanani aphansi.

Enye ye-analogues ingabizwa ngokuthi ithuluzi elibizwa nge-Alumina, olutholakala ezibhebheni. Futhi iqukethe into esetshenziswayo ye-acarbose, evimba ushukela.

Amapilisi we-Glucophage Ukudla

Njengoba i-Glucobai yokulungiselela ukulahleka kwesisindo ehambisana nayo ithi isithako esisebenzayo kubo yi-acarbose, kungenzeka ukuthi ungene esikhundleni somuthi nge-analogue engabizi kakhulu.

Ine-drug Glucobay analogues, enjengeGlucofage, iSiofor, iMetfogamma ne-Gliformin. Kodwa-ke, imiphumela yale mishanguzo isuselwa kwenye into esebenzayo - i-metformin, nayo eyi-carbohydrate blocker.

Ukudla amaphilisi Siofor

Njengoba wazi, yi-metformin engasebenzi kahle uma uyiqhathanisa ne-acarbose. Kepha, ngaphandle kwalokhu, inezinzuzo zako, okubandakanya:

  • ukuthuthukiswa kwe-lipid metabolism;
  • ukucindezelwa kwesifiso sokudla ukudla okumnandi.
I-Glucobuy iyasebenza ngempela ekunciphiseni isisindo, ngoba ilawula ukugcinwa kwe-insulin.

Izici zohlelo lokusebenza

Lapho ulapha ngalo muthi, kubalulekile kakhulu ukulandela ukudla okuqinile, okuqeda ngokuphelele ukusetshenziswa kwemikhiqizo equkethe inani elihlaba umxhwele lama-carbohydrate.

Isiguli esithatha i-Glucobay, esingathengwa ngentengo ephansi, kufanele sitshelwe udokotela wakho ukuthi akunakwenzeka ukukhansela lesi sidakamizwa ngokwakho.

Lokhu kungumsebenzi kadokotela kuphela abhekwe kuye. Uma ungawunaki lo mthetho, ungathola ukwanda okungathandeki kwamazinga kashukela. Kukhona nengozi yemiphumela emibi eyandayo ebonwa ohlelweni lokugaya ukudla.
Uma, ngaphandle kokulandela ukudla okuqinile, izimpawu zanda kuphela, kufanele wehlise ngokushesha umthamo we-Glucobay.

Kubalulekile ukubheka iqiniso lokuthi i-acarbose ivimbela kakhulu ukuguqulwa kwe-sucrose ibe ushukela, ngakho-ke uma kwenzeka i-hypoglycemia, kumele isetshenziswe ukuyimisa.

Kubaluleke kakhulu ukuthi inothi elifanele ukusetshenziswa komuthi iGlucobai lenziwe ngempela embhalweni wezokwelapha wesiguli onesifo sikashukela.

Umuthi uyakwazi ukuthonya amandla okushayela izimoto nokulawula izindlela eziyinkimbinkimbi. Akunconyelwe futhi ukwenza imisebenzi yobungcweti ngesikhathi sokwelashwa nalesi sidakamizwa uma kuhlotshaniswa nokunakwa okuningana kwenqubo.

Amavidiyo ahlobene

Izici ze-Pharmacological kanye nemiyalo esetshenziselwe isidakamizwa Glucobay:

I-Acarbose iyinto esebenzayo yesidakamizwa Glucobay, intengo yayo etholakala kumakhemisi. Uma izindleko ziphezulu kakhulu, ungathenga i-analogue engabizi kakhulu enomphumela ofanayo ngokuphelele. Kusukela mayelana nomuthi i-Acarbose (Glucobai) wokunciphisa isisindo, ukubuyekezwa kwezidakamizwa kuyinto enhle, okusikisela ukuthi kusebenza kahle hhayi kuphela ekwelapheni ukukhiqizwa okunganele kwe-insulin ye-hormone, kodwa futhi nokwehlisa isisindo, kungasetshenziswa ngokuphepha kulo msebenzi onzima.

Ukuphela kwento okumele ibonwe ngaphambi kokuthatha la maphilisi ukuthi udokotela oholayo kuphela ongabanika wona. Akunconywa ukuthi uzithathe ngaphandle kokubonana nodokotela, ngoba ungadala omkhulu iminyango kuyo yonke iminyango nezinhlelo zomzimba. Kufanele futhi kukhunjulwe ukuthi umuthi uhlakazwa ngemithi kuphela, ngakho-ke ukuvakashela uchwepheshe ofanele kuleli cala kuyimpoqo.

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