Isifo sikashukela sinika abantu izinkinga eziningi. Ngeshwa, akasebenzi ngokuphelele.
Ngakho-ke, iziguli eziningi ziphendukela kodokotela ukuze zisize ukuthuthukisa impilo yazo ngosizo lwezidakamizwa ezikhethekile.
Izidakamizwa ezisebenza kahle kakhulu ekulawuleni ukubonakaliswa kwesifo sikashukela yilezo ezinamandla okunciphisa ushukela egazini lomuntu.
Ithuluzi elinjalo yiMetfogamma, imfundiso echazwa ngokuningiliziwe izinkomba zokusetshenziswa, ukwakheka, ukuphikiswa nemiphumela emibi. Ungazijwayeza le mininingwane ekulesi sihloko.
Izinkomba zokusetshenziswa
Kubekelwe ushukela i-mellitus yohlobo lwesibili, olubizwa nangokuthi i-insulin-Independent, ngaphandle kokuthambekela kwe-ketoacidosis. Kusebenza kahle ikakhulukazi ezimweni ezihambisana nokuba khona kwesisindo ngokweqile.
Khipha ifomu
Iyatholakala kumathebhulethi, ahlanganiswe nengubo yokuvikela. Iqhubu elilodwa liqukethe amacwecwe ayishumi. Kepha iphakethe elilodwa lingaba nezibhebhe ezintathu noma eziyishumi nambili zamathebhulethi. Umthamo ungokulandelayo: 500 mg, 850 mg no-1000 mg.
Amathebhulethi e-Metfogamma 1000 mg
Ukwakheka
Isakhi esisebenzayo yi-metformin hydrochloride. Ngaphezu kwakho, amaphilisi aqukethe i-hypromellose, i-povidone ne-magnesium stearate. Ukuqanjwa kolwelwesi kufaka phakathi i-hypromellose, macrogol, kanye ne-titanium dioxide.
Isenzo se-Pharmacological
Lesi sidakamizwa siyi-ejenti ekhethekile ye-hypoglycemic, okuhloselwe ukuphathwa ngomlomo.Ezigulini ezinezinhlobo ezahlukahlukene zesifo sikashukela, iMetfogamm isiza ushukela ongezansi ngokuvimbela i-gluconeogenesis emgodini secretion wangaphandle, inciphisa ukumuncwa kwe-glucose emgodini wokugaya ukudla futhi yandise ukucubungula kwayo ezicutshini zezitho ngokwandisa umuzwa wayo we-pancreatic hormone.
Imiyalo yokusebenzisa umuthi obizwa ngeMetfogamma 850 yazisa ukuthi ayithuthukisi imfihlo yokuqokwa kwe-insulin ngamangqamuzana pancreas futhi ayibangeli zimpendulo ezingalindelekile nezingathandeki. Lesi sidakamizwa siyakwazi ukuthinta imetabolism.
Imininingwane ekhethekile
Ngesikhathi sokulashwa ngalo muthi, kuyadingeka ukuqapha ukusebenza nokusebenza kwezinso.
Kubalulekile kakhulu ukwenza ukuzimisela kwe-plasma lactate okungenani kabili ngonyaka.
Uma kunokuthuthuka okusheshayo kwe-lactic acidosis, khona-ke kuyadingeka ukuthi uqede ngokushesha ukwelashwa. Akunconyelwe ukusebenzisa izifo, ukulimala nengozi yokuphelelwa amanzi emzimbeni.
Ngokulashwa okuxubile kusetshenziswa i-sulfonylureas, kufanele kuqinisekiswe ukuqapha ngokucophelela izinguquko emazingeni kashukela.
Indlela yokusebenzisa
Udinga ukuphuza amaphilisi kuphela ngaphakathi ngesikhathi sokudla noma ngemuva.
Iziguli ezinesifo sikashukela ezingayitholi i-insulin ebalulekile kufanele zithathe amaphilisi amabili kabili ngosuku ngezinsuku ezintathu zokuqala.
Ungazama futhi ukuqala ukuthatha ithebhulethi elilodwa (500 mg) kathathu ngosuku, ngokwanda okuthe xaxa komthamo kabili. Ukusuka cishe osukwini lwesine kuze kube sekupheleni kwesonto lesibili lokuphatha, udinga ukuthatha amaphilisi amabili ngomthamo ka-500 mg ngesikhathi kathathu ngosuku.
Ngemuva kokudlula amasonto amabili kusuka kulo mzuzu, umthamo ungaphinde wehliswe, kucatshangelwa amaphesenti kashukela egazini nomchamo. Umthamo wokulungisa ulinganiselwa ku-2 g ngosuku. Uma isiguli sithola i-insulin ngomuthi ongaphansi kwamayunithi angama-40, isilinganiso salo muthi ngosuku sihlala sinjalo.
Contraindication
Imiyalo yokusetshenziswa kwesidakamizwa iMetfogamma, intengo yayo etholakala kunoma iyiphi ikhemisi, iqukethe le mibiko elandelayo:
- infarction myocardial;
- ukwephula kwamazwi kokusebenza okujwayelekile kwezitho zohlelo lokukhuphuka;
- ukungakwaneli kwezitho zamasistimu wezinhliziyo nezokuphefumula;
- i-ketoacidosis, i-precoma ne-coma;
- ukuphazamiseka kokunikezwa kwegazi emithanjeni yobuchopho;
- ukomisa;
- i-lactic acidosis;
- uphuzo oludakayo;
- ubuthi botshwala;
- ukuzwela okuphezulu kuzakhi ngazinye zomuthi, ikakhulukazi entweni esebenzayo;
- ukukhulelwa
- ukuncelisa.
Akunconyelwe ukusetshenziswa ngabantu abasesigabeni sabantu abangaphezulu kweminyaka engamashumi ayisithupha abasebenza kanzima, abadinga inani elikhulu lamandla. Futhi, ithuluzi liyakwazi ukuthonya ukuphathwa kwezindlela zokuhamba nezindlela eziyinkimbinkimbi, ngoba kunciphisa ukunakwa kokunakwa. Ngakho-ke, ngesikhathi sokwelashwa kungcono ukungabeki impilo yakho engozini kanye nezimpilo zabanye abantu. Ukuze wenze lokhu, kufanele ukhawule ukusetshenziswa kwemoto ngesikhathi sokulashwa nalesi sidakamizwa.
Imiphumela emibi
Imiyalo yokusebenzisa iMetfogamma 1000 ixwayisa ngokuthi imibandela elandelayo iyenzeka:
- isicanucanu nokuhlanza
- ukunambitheka okubizwa ngokuthi “kweqiniso” endaweni yomlomo;
- ukulahleka kwesifiso sokudla;
- dyspepsia
- ukuqhakaza nobuhlungu kuwo;
- i-lactic acidosis;
- ukozela
- i-hypovitaminosis B12;
- ukwehlisa umfutho wegazi;
- i-hypothermia;
- ukuqhuma kwesikhumba okwenzeka ngesikhathi sokuphendula komzimba.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Imiyalo yokusebenzisa iMetfogamma ithi kwenqatshelwe ngokuphelele ukuyisebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba.
Isikhathi sokuhlela ukukhulelwa naso sifanelwe ukunakwa ngokukhethekile.
Ngalesi sikhathi, uma isiguli besiphuza umuthi, kufanele simiswe masinyane futhi ukwelashwa nge-hormone yamanyikwe kufanele kunqunywe.
Kubaluleke kakhulu ukuthi isiguli sazise udokotela uma ekhulelwe. Umama nengane kufanele kugadwe. Okwamanje, akwaziwa ukuthi into esebenzayo yesidakamizwa ikhishwa kanye nobisi lwebele noma cha. Ngakho-ke, uma umama enakekela ngokucophelela impilo yengane yakhe, ukusetshenziswa kwamathebulethi kufanele kuyeke ngesikhathi sokuncelisa ibele.
Ukweqisa
Amacala okweqisa ngalesi sidakamizwa okwamanje ayaziwa. Olunye lwezimpawu yi-lactic acidosis.
Ukwelashwa kwalesi simo kuqukethe ukuyekela okuphelele kokuthatha amaphilisi, i-hemodialysis kanye nokwelashwa okubonisa izimpawu.
Imbangela yokuqothuka ngokweqile kwe-lactic acid emzimbeni kungenzeka kube ukwanda komuthi ngenxa yokuphazamiseka okujwayelekile kokusebenza kwezinso. Izimpawu zokuqala futhi eziphazamisayo ze-lactic acidosis yisifiso sokuhlanza, isifo sohudo, ukwehla kwezinga lokushisa lomzimba, izinhlungu ezingabekezeleleki esiswini nasemisipha, ukuphefumula ngokushesha, ukushuba kwengqondo futhi, ngenxa yalokho, ukoma.
Ukuhlanganiswa neminye imithi
Okwamanje, kunezinhlanganisela ezingatuswa ukuthi uzisebenzise.
Inhlanganisela yeMetfogamm neDanazole, izidakamizwa eziqukethe i-ethanol, i-Chlorpromazine nezinye izindlela ezifanayo ayifiseleki.
Lapho isetshenziswa ngama-antipsychotic nangemva kokukhanselwa kwabo, umthamo weMetfogamma kufanele ulungiswe. Kepha ama-glucocorticosteroids anokusebenzisa kwabazali nabasendaweni kunciphisa kakhulu ukubekezelelwa kwe-plasma glucose, kwezinye izimo kuvuselela i-ketoacidosis.
Uma kunesidingo esiphuthumayo sokusebenzisa i-loop diuretics ne-metformin esebenzayo yezinto, kunengozi ye-lactic acidosis ngenxa yokuvela kokuhluleka kokusebenza kwe-renal, futhi ukuvela kwayo kungenzeka futhi ngesikhathi sokuhlolwa kwe-radiological usebenzisa ama-Special iodine aqukethe i-iodine agents.
Ukwelashwa ngomuthi kufanele kukhanseliwe ezinsukwini ezimbili ngaphambili futhi kungavuselelwa ngaphambi kwesikhathi esifanayo ngemuva kwe-x-ray ngokusebenzisa izingoma ezikhethekile ze-iodine eziqukethe i-iodineque.
Amavidiyo ahlobene
I-Metformin yezidakamizwa iyi-analogue yeMetfogamma. Ungawuthatha kanjani lo muthi, bheka ividiyo:
Imiyalo yokusebenzisa iMetfogamma 500, engathengwa kunoma iyiphi ikhemisi ngentengo engabizi, inemininingwane enemininingwane yokuthi ungayithatha kanjani ngokufanele. Ngaphambi kokuthi uqale ukwelashwa ngalo muthi, udinga ukubonana nodokotela wakho. Kubaluleke kakhulu futhi ukuthi uzijwayeze ngokucophelela ngomphumela we-pharmacological, contraindication, imiphumela engathandeki nolunye ulwazi olubalulekile umyalo oqukethe ngaphambi kokuqala ukuthatha. Lokhu kuzovikela umzimba emiphumeleni emibi yesidakamizwa uma kungafanele umuntu othize. Ngaphezu kwalokho, uma kwenzeka ngokweqile kunengozi yokufa. Ngakho-ke, kubalulekile ukubala ngokucophelela umthamo ukuze ungalimazi, kepha, kunalokho, unciphise ukugcwala kwe-glucose ku-plasma yomuntu.
