Ukwehlulwa kwezakhi zesistimu yezinzwa ephakathi nendawo. Lokhu kuyinkimbinkimbi yesibonakaliso, okuwukuphazamiseka kwesimo esisebenzayo sayo yonke imicu yezinzwa ngokumelene nesizinda sezinguquko ezenzeka emithanjeni yegazi emincane. I-neuropathy yesifo sikashukela (ngokusho kwe-ICD-10 - G63.2 *) idinga ukuhlolwa okusheshayo kwesimo nokuqokwa kokwelashwa okufanele ukuze kubuyiswe imisebenzi elahlekile futhi kuthuthukiswe impilo yempilo yesiguli.
Ukuhlukaniswa
Ngesikhathi sokuhlolwa, i-pathology iyatholakala kuzo zonke iziguli zesithathu eminyakeni eyi-10-15 ngemuva kokuqala kwesifo sikashukela. Ukwahlukanisa i-neuropathy yemvelo ephakathi nethintekile. Ukulimala kobuchopho kanye nentambo yomgogodla kungokwenqubo ye-pathological ephakathi nendawo futhi kuhlukaniswe ngale mibandela elandelayo:
- ukuqubuka komzimba okuphezulu ngemuva kokulimazeka kwezakhi zohlelo lwezinzwa oluphakathi;
- ingozi ye-cerebrovascular eyingozi;
- ukungasebenzi kahle kobuchopho ngokumelene nesizinda se-pathology yezinso;
- i-neurosis;
- isifo sokuqina kwesifo sikashukela;
- i-myelopathy ngokumelene nesifo sikashukela.
I-peripheral diabetesic neuropathy nayo inesigaba esekwe eminyangweni yomonakalo:
- izinzwa ezibucayi - ezibucayi ziyabandakanyeka kule nqubo;
- ukusebenza kwemoto - ukungasebenzi kahle kwezinzwa zemoto;
- i-sensorimotor - ukulimala kwemizwa nezinzwa zemizwa;
- ezizimele - i-neuropathy yezitho zangaphakathi.
Ngokusekelwe ezicini zenqubo yomtholampilo, lezi zinhlobo ezilandelayo zesifo sikashukela se-diabetes zihlukaniswa:
- uhlobo olungasasebenzi - izinguquko ezembulwe ngesikhathi sokuhlolwa kuphela ezibonisa ukuba khona kwe-pathology, isiguli asinazikhalazo;
- Uhlobo lomtholampilo: ifomu eliyingozi, elihambisana nobuhlungu; ifomu elingamahlalakhona ngobuhlungu; ukubonakaliswa komtholampilo ngaphandle kobuhlungu.
- izinkinga (isifo sikashukela, ukuwohloka kohlobo lwe-neuropathic).
Indlela yokuthuthukiswa kwe-pathology
Ngokuphikisana nesizinda sikashukela i-mellitus, i-hyperglycemia ejwayelekile (ukwenyuka kweglucose yegazi) kuyabonakala. Lokhu kungahle kube ngenxa yokwehluleka kwama-pancreas ukuhlanganisa i-insulin eyanele (uhlobo lwe-1 isifo) noma ivele ngenxa yokuncipha kokuzwela kwamangqamuzana nezicubu ukungena kwe-insulin ngesikhathi sokukhiqizwa kwayo okuvamile (uhlobo 2 lwesifo).
I-Hyperglycemia iyimbangela eyinhloko yokwanda kwezinkinga zesifo sikashukela.
Amazinga kashukela aphezulu aphazamisa zonke izinqubo ze-metabolic. Kwi-vasotine endothelium, i-sorbitol, amaprotheni e-glycosylated, aqongelela. Lokhu kudala ushintsho ekusebenzeni okujwayelekile nokwakheka kwamangqamuzana ezinzwa (ama-neurons). Indlala ye-oksijini kanye nezindawo ezinokunganele kwegazi zinezela ekuthuthukiseni ukucindezelwa kwe-oxidative. Umphumela uwukuntuleka kwezimpawu ze-neurotrophic kanye nokukhula kwe-neuropathy yesifo sikashukela.
Izithombe zemitholampilo
Izimpawu ze-neuropathy yesifo sikashukela zincike kwifomu, ubukhulu, isilinganiso sokuthuthuka nomlando wokwelashwa osetshenzisiwe.
Ukuphazamiseka kweSensomotor
Leli fomu livame kakhulu kubantu abaphethwe “isifo esimnandi”. Ukuboniswa kwenkambo engapheli:
- izinhlungu zemvelo ehlukile;
- i-paresthesia;
- ukukhubazeka
- ukunciphisa kufinyelele ekuntuleni okuphelele kokuzwela ekushintsheni kwezinga lokushisa nokudlidliza;
- ubuthakathaka bemisipha;
- imiphetho yemikhawulo ephansi;
- ukuntuleka kokuqonda okujwayelekile ngokucasuka;
- ukubonakala kokuqagela kwe-pathological.
Ukuphazamiseka kwemizwa okunamandla
I-Sensory diabetesic neuropathy ihambisana nezikhalazo ezilandelayo zeziguli:
- ukukhuphuka kokuzwela kokungabonakali kokushintsha kwezinga lokushisa, ukuthinta, ukudlidliza;
- ukuphazamiseka kobuzwela ngesimo sokuqonda okunganele;
- ukubonakala kobuhlungu ekuphenduleni umthelela walezo zici ukuthi ngaphansi kwezimo ezijwayelekile azibangeli buhlungu;
- ikhaliphe ingahlala ijwayelekile;
- isifo sobuhlungu obukhulu.
Ubuhlungu bungavutha, ukudonsa, ukudubula, okokuqala kuvela ezinyaweni nasemilenzeni, lapho imikhumbi ihlangana khona kakhulu.
Ukwehla, ukudinwa, ukuqaqamba - ukubonakaliswa kwethambo lomzimba
Ngefomu le-asopmetic le-neuropathic, ukuqina kwesisu kubonakala endaweni ye-pelvic, ukuhlangana kwe-hip, kwehlela phansi emlenzeni kusuka ohlangothini lapho kulimale khona ama-neurons. Lesi simo sihambisana nokuncipha kwenani lamafutha, ukwehla kwesisindo semisipha yomlenze "obuhlungu".
Ungafunda kabanzi nge-neuropathy yesifo sikashukela semikhawulo ephansi kusuka kule ndatshana.
Ifomu leStrone
Izilonda zamaseli ezinzwa zezitho zangaphakathi zihambisana nezinga lokufa eliphakeme phakathi kweziguli ezinesifo sikashukela i-mellitus. Izinhlobo ezivame kakhulu nezinobuntu be-pathology zichazwe etafuleni.
Ama-Organs nezinhlelo | Izimpawu | Umtholampilo |
Inhliziyo, imikhumbi | I-Cardiac denervation syndrome, i-orthostatic hypotension, ukuzwela okuphazamisekile emsebenzini womzimba, i-edema ye-pulmonary edema | Ukuphazamiseka kwesigqi senhliziyo (i-tachycardia, i-arrhythmia), umfutho wegazi ophakeme, ushintsho lwe-ECG, ukukhwehlela "kwenhliziyo", ukushesha komoya, ukufa ngokuzumayo |
Amapheshana wesisu | I-Gastroparesis, i-atony yamathumbu, i-dysbiosis, i-pancreatitis, isifo se-Reflux, izinhlungu | Isicanucanu, ukuhlanza, ubuhlungu besisu, ukuqhakaza, ukushisa kwenhliziyo, ukwehla okukhulu kwesisindo somzimba, uhudo |
Isistimu ye-genitourinary | I-Atony, i-Reflux, ukutheleleka, ukungasebenzi kahle kwe-erectile | Ubuhlungu ngaphezulu kwe-pubis, ukwephulwa kwenqubo yokuchama, ukuphuma kwe-pathological kusuka kwi-urethra kanye ne-vagina, ubuhlungu emhlane ongezansi, i-hyperthermia |
Uhlelo lokuxolisa | Anhidrosis, hypohidrosis, hyperhidrosis | Ukungabi khona, ukwehla noma ukukhulisa umjuluko ngesikhathi sokudla kanye nokuzivocavoca umzimba |
Uhlelo lokubumbana kwabafundi | Ukulimazeka kokubonakalayo | Ukunciphiswa kububanzi babafundi, ukusabela okuthe chu ezishintsheni ekufikeni kwamagagasi okukhanya, i-pathology of ukubona kokuhlwa |
Izindlala ze-Adrenal | Ukuntuleka kokwethulwa kwemitholampilo |
Ukuxilongwa kwe-Neurological
Ukwelashwa kunqunywa kuphela ngemuva kokwehlukanisa nokuxilonga. Ukuhlolwa nokuqoqwa kwezikhalazo zesiguli kuhambisana nokuhlolwa kwengqondo. Uchwepheshe ucacisa isimo sobuhlungu, ukuthambisa, ukushisa, ukubanda, ukuzwela kokudlidliza. Iqoqo le-neurologist lokuxilongwa lifaka:
- i-malleus enenalithi eyakhelwe ngaphakathi - ukuhlola isimo sokuzwela kobuhlungu;
- IV - ihlaziya imizwa yokuthula kwesiguli;
- i-monofilament - incazelo yokuzwela nge-tactile;
- ukugeleza kwemfoloko - bonisa izinga lokuzwela kokudlidliza;
- i-malleus ene-brashi - imizwa ye-tactile.
Izinhlobo zezinkinga zokuxakeka zingadinga i-biopsy yezinzwa zamathole nesikhumba somzimba ngokuhlolwa okwengeziwe komlando.
Ukuhlolwa kwe-Reflex kungenye yezigaba zokuxilongwa kwe-neurological
Isazi sezinzwa sinquma izifundo ze-electrophysiological. I-Electromyography ikhombisa umsebenzi we-bioelectric wokusebenza kwemisipha nokudluliselwa kwe-neuromuscular of impulses. Imininingwane etholakele yenza sikwazi ukubona isimo sezinzwa esisebenzayo, esibhekele ukwenziwa kwengxenye ethile yomzimba, ukwembula umonakalo ezingxenyeni eziyingxenye zesistimu yezinzwa.
I-Electroneurography iyinhlangano ekhombisa ukuthi ijubane lokudlula kwethambo lezinzwa ngokuhambisana nemicu yethrafikhi evela endaweni lapho ikhipha khona uhlelo lwangaphakathi lwezinzwa iye kuma-nerve receptors akhiwe kwimisipha nesikhumba.
Amandla afakiwe - lolu cwaningo olukhombisa umsebenzi we-bioelectric wamaseli wezinzwa nezicubu besebenzisa izishukumisi ezahlukahlukene (ezibukwayo, ezinamazwi, ezithinta).
Ezinye izindlela zokucwaninga
Ngaphezu kwe-endocrinologist, udokotela wezifo zesisu, uchwepheshe wezifo zenhliziyo, udokotela wezifo zamehlo ubamba iqhaza ekuhlolweni kwesiguli. Kwabelwa izifo zokuxilonga elabhorethri:
- ukuzimisela kashukela wegazi;
- i-biochemistry yegazi;
- i-glycosylated hemoglobin;
- ukunqunywa kwenani le-insulin;
- I-peptide.
Udokotela wezinhliziyo unikeza ukuhlolwa kweValsalva, iHolter ECG, i-echocardiography, ukuhlolwa kwamathambo. Udokotela osesiswini uhlola isimo sepheshana esiswini nge-ultrasound, endoscopy, x-ray yesisu, ukuhlolwa kwelabhoratri ukuthola ukuthi ukhona yini uHelicobacter pylori.
I-ECG - enye yezindlela zokutadisha ukulimala kokufakwa ngaphakathi kwezinzwa zohlobo lokuzimela
Ukuhlolwa kwesimo esisebenzayo sohlelo lwe-urinary kususelwa ekuhlaziyeni komchamo, i-ultrasound, i-cystoscopy, i-urravenous urography, i-electromyography yamathuluzi wemisipha yesinye.
Ukwelashwa
I-neuropathy yesifo sikashukela, ukwelashwa okufanele kuqale ngokulungiswa kweglucose yegazi, kudinga ukwelashwa ngezigaba. Ukuze wenze lokhu, sebenzisa imijovo ye-insulin (yohlobo 1 sikashukela) noma izidakamizwa ezinciphisa ushukela (isifo sohlobo 2). Isidingo kukulawula ushukela ku-dynamics ngezindlela zaselebhu kanye nendlela yokuzithiba.
Ukwelashwa kwezinkinga kuhambisana nokulungiswa kokudla, ukusebenza komzimba nokuphumula, ukunciphisa isisindo somzimba we-pathological, ukudala izimo zokugcina ingcindezi ezingeni elijwayelekile.
Izidakamizwa ezokwehlisa ushukela ezisetshenziselwa ukulungisa amazinga kashukela:
- I-Metformin
- Maninil
- Victoza
- UJanuvius
- Isifo sikashukela
- I-Novonorm.
Ukulungiswa kwe-Thioctic acid
Imithi yenza ngokwejwayelekile i-lipid metabolism, ilawule i-cholesterol. Kusho ukuthuthukisa ukusebenza kwesibindi, ukunciphisa imiphumela enobuthi. Abamele iqembu:
- I-Berlition,
- I-Tiogamm
- I-Liopthioxone
- I-Lipoic acid.
Abacindezeli
Le mishanguzo isetshenziselwa ukumisa i-pain syndrome eyaqhamuka ngemuva kwesizinda se-neuropathy. Faka isicelo se-amitriptyline, imipramine, i-nortriptyline. Izindlela zokwelapha ezimbili zokuqala zinobuthi obuncane futhi zibangela imiphumela emibi emincane. Ukuqedwa kobuhlungu kuvela kancane ngaphambi kokuba umphumela we-antidepressant ube khona.
I-Amitriptyline iyi-antidepressant ephumelelayo enobuthi obuncane emzimbeni.
Abantu asebekhulile nalabo abahlushwa i-encephalopathy, i-neurosis, izimo ezihlolayo kufanele baphuze izidakamizwa ngaphansi kokuqashwa okuphezulu kongcweti noma izihlobo. Umuthi onganele ungabulala.
Ama-analgesics nama-anesthetics
Ibuye isetshenziselwe ukudambisa izinhlungu. Izicelo ezenziwe nge-anesthetics yendawo (Lidocaine, Novocaine) ziyasetshenziswa. Uma kuqhathaniswa nama-antidepressants, ukusebenza kwawo kwe-analgesic kuncane, kepha kusetshenziselwa ukuzilolonga. Ukwenza ngcono isimo sesiguli kwenzeka ngemuva kwemizuzu eyi-10-15.
Ama-analgesics ngesimo se-Analginum, Paracetamol awaphumeleli, noma kunjalo, amacala okuqokwa kwawo angenasisekelo ayaziwa.
Amavithamini we-B-Series
Amalungiselelo e-Vitamin asetshenziselwa ukwenza uhlelo lwezinzwa lube ngokwejwayelekile IPyridoxine iyathandwa (B6), thiamine (B1) ne-cyanocobalamin (B12) Isikimu sokukhethwa kukhethwe uchwepheshe ngamunye.
Ama-anticonvulsants
I-Carbamazepine, i-Finitoin bangabameleli abaphumelelayo baleli qembu, abadinga ukukhethwa ngokucophelela komthamo ngenxa yemiphumela emibi engaba khona. Qala ukuthatha imithamo emincane, kancane kancane ulethe ekwelashweni okudingekayo. Le nqubo ayidingi ngisho nezinsuku ezimbalwa, kodwa amasonto angama-3-4.
Ezinye izindlela zokwelapha
Ukwelashwa kwe-neuropathy yesifo sikashukela kusebenzisa kakhulu izindlela ezingezona izidakamizwa:
- isicelo se-laser;
- ukubola kwezinzwa ezinkulu;
- i-magnetotherapy;
- i-acupuncture;
- ukuvusa kagesi okushintshayo.
Ukuzimisela ngesikhathi ukuthuthukiswa kwe-pathology kanye nosizo lwabachwepheshe abaqeqeshiwe kuzosiza ekugcineni impilo yesiguli ezingeni eliphakeme futhi igweme izinkinga ezinkulu.