Ukuze ulwe nezimpawu zesifo sikashukela, udokotela angakunikeza umuthi i-Okolipen.
Iziguli kufanele zazi ukuthi leli khambi liphawuleka kangakanani nokuthi lithinta kanjani umzimba.
Ngaphezu kwalokho, kufanele uthole ukuthi iziphi izici zomuthi ezingakuholela ezinkingeni. Lokhu kuzosiza ukugwema izenzo ezingalungile futhi kukwenyuse ukusebenza kwezokwelapha.
Imininingwane ejwayelekile
I-Oktolipen isuselwa ku-thioctic acid. Kwesinye isikhathi lesi sidakamizwa singabizwa ngokuthi yi-lipoic acid, ngoba siqukethe isakhi esifanayo. Lesi sidakamizwa sihlose ukuqeda izifo eziningi.
Inezici ezimbalwa eziwusizo:
- i-hepatoprotective;
- i-hypoglycemic;
- i-neuroprotective;
- hypocholesterolemic.
Ungathola ukuthi kungani i-Oktolipen inqunywe, kusukela kwimiyalo. Ilungele ukwelashwa kwesifo sikashukela, kepha kukhona ezinye izindlela zokususa ezidingekayo.
Udokotela kufanele anikeze umuthi. Ungabheka ukuthi kufaneleka kanjani ukuyisebenzisa esimweni esithile, akhethe umthamo ofanele futhi alandele inkambo yokwelashwa.
I-Oktolipen ikhiqizwa eRussia. Ukuthenga lo mkhiqizo ekhemisi kufanele ulethe incwadi kadokotela.
Ukwakheka, ifomu lokukhulula
Umuthi uyatholakala ngezindlela eziningana (amaphilisi, amaphilisi, umjovo). Ukuzikhethela kwezinhlobo zomuthi kuya ngezimpawu zomzimba wesiguli kanye nohlobo lwesifo. Imisebenzi esemqoka ye-Octolipen yi-thioctic acid, okuyisakhi esiyinhloko.
Kumathebhulethi namaphilisi kwangezwa izinto ezifana:
- i-calcium hydrogen phosphate dihydrate;
- i-gelatin yezokwelapha;
- i-magnesium stereate;
- titanium dioxide;
- isilika;
- udayi.
Amathebhulethi namakhebhi ahlukile ngombala. Umthamo wento esebenzayo kubo ngu-300 no-600 mg. Athengiswa emaphaketheni amayunithi angama-30 no-60.
Isixazululo sokufakwa sisesimweni se-liquid, asinayo imibala futhi esobala.
Izici ezisizayo zokuqanjwa kwazo yilezi:
- amanzi
- i-edetate disodium;
- ethylenediamine.
Ukuze kube lula, lolu hlobo lwe-Oktolipen lubekwa kuma-ampoules.
I-Pharmacology ne-pharmacokinetics
Ingxenye esebenzayo inomphumela obanzi emzimbeni. Lapho kuthathwa ezigulini, ukugxilisa ushukela wegazi kuyancipha, ngoba i-thioctic acid ithuthukisa umuzwa we-insulin. Ngokufanelekile, ushukela udonswa amandla amaseli futhi asatshalaliswa izicubu.
I-Acid iyayidambisa imiphumela yezinto ezingamagciwane, ihlanza umzimba wezinto ezinobuthi futhi isize ukuqinisa ukungatheleleki komzimba. Ngenxa yalokho, inani le-cholesterol liyancishiswa, elivimbela ukuthuthukiswa kwe-atherosclerosis. Ngaphezu kwalokho, i-acid ithuthukisa umsebenzi wesibindi, ithinta izinqubo ze-lipid ne-carbohydrate metabolism.
Lapho kuthathwa ngomlomo, ingxenye yokwelapha iyabanjwa futhi isatshalaliswe ngokushesha. Ukuhlushwa kwayo okuphezulu kufinyelela ngemuva kwemizuzu engama-40. Ukusebenza okuhle kakhulu kungatholakala ngomjovo. Inqubo yokutholwa ithintwa yisikhathi sokudla - kuyalulekwa ukusebenzisa lesi sidakamizwa ngaphambi kokudla.
I-Acid icutshungulwa yisibindi. Iningi lale nto lisuswa emzimbeni ngokusebenzisa izinso. Half-life kuthatha ihora.
Ividiyo mayelana nezakhiwo ze-thioctic acid:
Izinkomba kanye ne-contraindication
Ukuhlukumeza isidakamizwa noma ukusetshenziswa kwaso ngaphandle kwesizathu kungalimaza isiguli.
Izinkomba zokusetshenziswa kwomuthi:
- i-polyneuropathy ebangelwa ushukela noma uphuzo oludakayo (ukwelashwa kwenziwa kusetshenziswa amaphilisi);
- ubuthi ngokudla noma ngezinto ezinobuthi;
- ukuqina kwesibindi;
- hyperlipidemia;
- uhlobo lwe-hepatitis A (kulezi zimo, ukusetshenziswa kwesisombululo somjovo kuhlinzekiwe).
Futhi, ithuluzi linganconyelwa izifo ezingaveli ohlwini lwezinkomba. Lokhu kuvunyelwe ekwelashweni okuyinkimbinkimbi.
Ukuba khona kokuxilongwa okufanelekile yinto ebaluleke kakhulu, kepha ukungabikho kokuphambana kubhekwa njengokubaluleke kakhulu. Uma zitholakala, ukusetshenziswa kwe-Oktolipen kuyenqatshelwe.
Contraindication ifaka:
- ukungabekezelelani kwezakhi;
- ukuzala ingane;
- ukondla kwemvelo;
- iminyaka yezingane.
Ezimweni ezinjalo, i-Octolipen yezidakamizwa ifuna ukumiselela phakathi kwe-analogues.
Imiyalo yokusebenzisa
Thatha i-Octolipen ngokwemithetho elandelayo:
- Ukulungiswa kwethebhulethi kusetshenziswa kuphela ngomlomo futhi kuphela esiswini esingenalutho. Musa ukugaya noma ukuhlafuna.
- Umthamo olawulwa kakhulu ngu-600 mg, kepha uma kunesidingo, udokotela angawukhulisa.
- Isikhathi senkambo yokwelashwa sincike esithombeni somtholampilo kanye nezindlela zokwelashwa ezisebenza ngayo.
- Imijovo kufanele ifakwe emthanjeni. Ukulungiselela ukwakheka, udinga ama-ampoules ama-1-2 womuthi. Zixutywe nekhambi le-sodium chloride.
- Umthamo ojwayelekile uma usebenzisa ifomu loketshezi lomuthi ngu-300-600 mg. Isikhathi sokudalulwa okunjalo kungahluka.
- Kaningi, esigabeni sokuqala sokwelashwa, isisombululo siyasetshenziswa (amasonto ama-2-4), bese isiguli sidluliselwa ku-Oktolipen ezibhebheni.
Ukukhetha imithamo kwenziwa ngamunye. Lokhu kuthonywa yizici eziningi ezahlukahlukene, futhi uchwepheshe kuphela ongazinaka.
Ividiyo ezakhiweni ze-alpha lipoic acid:
Iziguli Ezikhethekile Nezinkomba
Lapho unquma umuthi emaqenjini athile abantu, ukuqaphela kuyadingeka, ngoba imizimba yabo ingaphendula kulo muthi ngokungalindeleki.
Phakathi kwazo kukhona:
- Abesifazane abakhulelwe. Ngokusho kocwaningo, i-thioctic acid ayilimazi ingane noma ingane ebilindelile, kepha izici zemiphumela yayo azifundwanga ngokuningiliziwe. Ngakho-ke, odokotela bayakugwema ukunquma i-Oktolipen ngalesi sikhathi.
- Abesifazane abaqhuba ukondla kwemvelo. Akunamininingwane yokuthi into esebenzayo yesidakamizwa iyangena kubisi lwebele. Kulokhu, ngesikhathi sokuqunjelwa, leli thuluzi alisetshenziswa.
- Izingane nentsha. Kwakungenakwenzeka ukuthola ukusebenza nokuphepha kwe-thioctic acid kulesi sigaba seziguli, yingakho umuthi uthathwa njengento ephulwayo kubo.
Ezinye iziguli zingasisebenzisa lesi sidakamizwa uma zingabekezeleli.
Lapho usebenzisa i-Oktolipen kubantu abanesifo sikashukela, kufanele ukhumbule ngekhono le-thioctic acid lokunciphisa ushukela we-glucose.
Lokhu kungandisa umphumela wabanye ama-hypoglycemic agents uma isiguli sibathatha. Ngakho-ke, kufanele uhlole ngokuhlelekile amazinga kashukela wegazi futhi ushintshe umthamo wezidakamizwa ngokuya nawo.
Enye into ebalulekile yesidakamizwa ukuhlanekezela kwesenzo sayo ngaphansi kwethonya lotshwala. Kulokhu, ochwepheshe bayakwenqabela ukusetshenziswa kotshwala ngesikhathi sokwelashwa.
Futhi akukho mininingwane yokuthi u-Oktolipen wenza kanjani ngezinga lokuphendula kanye nesikhathi sokunaka. Ukugwema ubungozi obukhona, ukunakekelwa kufanele kuthathwe lapho ushayela kanye nemisebenzi eyingozi.
Imiphumela emibi kanye ne-overdose
Ukuthatha lo muthi kwesinye isikhathi kuholela emiphumeleni emibi.
Lokhu kufaka phakathi:
- ukungezwani komzimba (ukubonakaliswa kwayo kuhlukahlukene, kusuka kokupholile kuya kokuqinile);
- ukuphefumula kwenhliziyo;
- ukushisa kwenhliziyo;
- hypoglycemia
Uma zitholakala, kufanele uthintane nodokotela wakho. Ukwehla okuqinile kwemiphumela emibi kudinga ukuyekwa komuthi, futhi kwezinye izimo isiguli sidinga ukwelashwa.
Izimpawu ze-overdose zibonakala njalo uma isiguli silandela imiyalo. Kodwa ngokuzwela okwengeziwe kwe-thioctic acid, ukubukeka kwabo kungadala ngisho nengxenye evamile yomkhiqizo.
Okuvame kakhulu ukubonwa:
- ikhanda
- isicanucanu
- Ubuhlungu esiswini.
Ukuqedwa kwalezi zinto kuya ngohlobo lwazo.
Ukusebenzisana kwezidakamizwa kanye nama-analog
Ukuze ukwelashwa kukhiqize, kufanele kubhekwe izici ezilandelayo zomuthi:
- I-Oktolipen ithuthukisa imiphumela yabaphatheli be-hypoglycemic yomlomo kanye ne-insulin;
- uma uthathwa ndawonye, umuthi unganciphisa ukusebenza kweCisplatin;
- amalungiselelo aqukethe i-iron, i-magnesium noma i-calcium kufanele athathwe ngaphambi noma ngemuva kwe-Oktolipen ngegebe lamahora ambalwa;
- umuthi uthuthukisa izindawo zokulwa nokuvuvukala ze-glucocorticosteroids;
- ngaphansi kwethonya lotshwala, ukusebenza kwe-Octolipen uqobo kuyancipha.
Kulokhu, kuyadingeka ukuguqula umthamo womuthi futhi ugcine izikhathi ezimisiwe. Yize kungcono ukugwema ukuhlanganisa lesi sidakamizwa nezindlela ezingafanele.
Kwesinye isikhathi iziguli ziyenqaba ukuthatha lo muthi futhi zicelwa ukuba zikhethe ama-analogues ashibhile. Kwezinye izimo, ukufaka esikhundleni kuyadingeka ngenxa yezinkinga zalo muthi.
Izidakamizwa ezingaziwa zihlanganisa:
- I-Thiogma;
- Lipamide;
- I-Berlition, njll.
Ukuzikhethela kwama-esikhundleni we-Oktolipen kufanele kwenziwe ngumhlinzeki wezempilo.
Umbono wochwepheshe neziguli
Ukusuka ekubuyekezweni kodokotela mayelana nomuthi i-Okolipen, singaphetha ngokuthi kungenzeka ukuthi sinqunywe ekwelashweni okuyinkimbinkimbi kokunciphisa umzimba. Endabeni yesifo sikashukela, amathuba okuba nezinkinga ngendlela ye-hypoglycemia aphezulu.
Ukubuyekezwa kweziguli kunempikiswano impela - isidakamizwa siyasiza ekunciphiseni isisindo, kodwa sivezwa imiphumela emibi ejwayelekile.
Nginikeza i-Oktolipen ezigulini zami njalo. Zilungele abanye, ezinye hhayi. Ithuluzi lisiza ngokunobuthi, kwehlisa amazinga kashukela, abesifazane bavame ukucelwa ukuba banikeze ukunakekelwa kwesisindo. Kepha, njenganoma imuphi umuthi, udinga ukuthi uqaphele ngawo ngoba we-contraindication kanye nemiphumela emibi.
U-Ekaterina Igorevna, udokotela
Ngincoma i-Oktolipen kanye nezincazelo zayo kwiziguli ezinokweqile - kulokhu kuyasiza ngempela. Angikukhuthazi ukuyisebenzisa kwabanesifo sikashukela. Uma besebenzisa izidakamizwa ze-hypoglycemic, i-Oktolipen ingadala izinkinga.
U-Irina Sergeevna, udokotela
Angisithandanga lesi sidakamizwa. Ngenxa yalokhu, ushukela wami wehle kakhulu - udokotela akazange anake ukuthi nginesifo sikashukela. Ngenxa ye-hypoglycemia, ngagcina esibhedlela. Abanye abantu engibajwayele bancoma leli khambi, kodwa angifuni ukukufaka engcupheni.
UMikhail, oneminyaka engama-42
I-Okolipen esetshenzisiwe yokunciphisa isisindo. Esontweni lokuqala ngangizizwa ngingasenalutho; isicanucanu sasingihlupha njalo. Ngabe sengiyijwayela. Ngiyithandile imiphumela - ezinyangeni ezi-2 ngilahle ama-7 kg.
UJulia, oneminyaka engama-31 ubudala
Ukuthenga lesi sidakamizwa kumaphilisi, udinga kusuka kuma-ruble angama-300 kuye kwangama-400. Amathebhulethi (600 mg) abiza ama-ruble ayi-620-750. Intengo yokupakisha i-Oktolipen ngama-ampoules ayishumi ngama-ruble angama-400-500.