Izidakamizwa zeHypoglycemic zinqunyelwe isifo sikashukela. Ukwelashwa kwe-insulin kukuvumela ukuthi ulungise ushukela wegazi lakho. Leli qembu lezidakamizwa lifaka i-Insuman Rapid GT.
Igama Lezwe elingafanele
I-Soluble insulin (ubunjiniyela bezakhi zofuzo zabantu).
I-ATX
A10AB01.
Khipha amafomu nokwakheka
Isixazululo siyatholakala kuma-vials noma kuma-cartridge. Ukupakishwa nge-injector kaSolostar elahlekayo kuyenziwa.
Isithako esisebenzayo kulamanzi yi-insulin yabantu. Iqoqo lesisombululo ngu-3.571 mg, noma i-100 IU / 1 ml.
Isixazululo siyatholakala emabhodleleni noma kuma-cartridge, kuthengiswe okwenziwe nge-Solostar injectorable injector.
Isenzo se-Pharmacological
I-insulin equkethwe umuthi ihlanganiswa kusetshenziswa ama-biotechnologies emkhakheni wobunjiniyela bezakhi zofuzo. I-insulin inesakhiwo esifanayo nesomuntu.
Umphumela we-pharmacological uvezwa ngokuncipha kwamazinga kashukela. Kukhona ukwehla kwezinqubo ezonakalisayo, ukushesha kwemiphumela ye-anabolic. Umuthi ukhuthaza ukuhanjiswa kwe-glucose esikhaleni sangaphakathi, ukunqwabelana kwe-carbohydrate eyinkimbinkimbi kwezicubu zemisipha nesibindi. Ukuphuma kwe-pyruvic acid okuphuma emzimbeni kuyathuthuka. Ngokuphikisana nalokhu ngemuva, ukwakheka kwe-glucose kusuka ku-glycogen, kanye nakumamolekyuli wezinye izinto ezihlanganayo, kuyehla.
Indlela yokusebenza iyabonakala ngokwanda kwe-metabolism ye-glucose kuma-acid acid kanye nokwehla kwezinga le-lipolysis.
Ukusatshalaliswa kwama-amino acid ne-potassium kumaseli, i-protein metabolism iyathuthuka.
I-Pharmacokinetics
Ngokuphatha okuphansi, ukuqala komphumela kugcinwa kungakapheli isigamu sehora. Umphumela omkhulu uhlala kusuka emahoreni angu-1 kuye kwayi-4. Isikhathi esiphelele somthelela wokwelapha sisuka emahoreni ayi-7 kuye kwayi-9.
Yinde noma imfishane
Into esebenzayo ibonakala ngesikhathi esifushane sokusebenza.
I-Insuman Rapid GT isidakamizwa esiyi-hypoglycemic esibekelwe ushukela.
Izinkomba zokusetshenziswa
Amacala Oyalelayo:
- ukwelashwa kwe-insulin;
- ukuvela kwezinkinga zesifo sikashukela.
Kusetshenziswa usuku lwangaphambilini nangesikhathi sokungenelela kokuhlinzwa, ngesikhathi sokuvuselelwa ukuze kulondolozwe isinxephezelo se-metabolic.
Contraindication
Contraindication kwezokwelapha yi-hypoglycemia nokungabekezeleli ikhambi.
Ukusetshenziswa ngokucophelela kuyadingeka ezimweni ezifana:
- Ukwehluleka kwangempela nokwenziwa kwesibindi.
- Ukunciphisa imithambo yobuchopho kanye ne-myocardium.
- Iminyaka engaphezu kwengu-65.
- I-retinopathy eyandayo.
Ngezifo ezijoyine ngengozi, isidingo se-insulin singakhuphuka, ngakho-ke ukusetshenziswa kwalesi sidakamizwa nakho kudinga ukuqashelwa.
Ungayithatha kanjani i-Insuman Rapid GT
Isixazululo senzelwe ukuphatha okuphathelene nokungena ngaphakathi nokuthambile. Azikho imithamo eyodwa elawulwa yesidakamizwa. Uhlobo lokwelashwa lufuna ukulungiswa ngakunye ngudokotela ohambelayo. Iziguli ezahlukahlukene zinamazinga ahlukahlukene we-glucose okuhlushwa okudingekayo ukuze kulondolozwe, ngakho-ke, inani lomuthi kanye nohlu lokwelashwa lubalwa ngokwahlukana. Udokotela ohambelayo ubheka ukusebenza komzimba wesiguli nezimpawu zokudla okunempilo.
Isidingo sokushintsha inani lomuthi kungenzeka emacaleni:
- Lapho ushintsha umuthi nolunye uhlobo lwe-insulin.
- Ngokuzwela okukhulu kwento ngenxa yokulawulwa okuthuthukile kwe-metabolic.
- Lapho ulahlekelwa noma uthola isisindo ngesiguli.
- Lapho ulungisa umsoco, uguqula ubukhulu bemithwalo.
Indlela eqondile yokuphatha yenziwa esibhedlela, njengoba izimo ezidingekayo zokubheka isimo sesiguli.
Ukuphatha kokuzenzakalelayo kujule. Kunconywa ukwenza inqubo imizuzu eyi-15 noma engama-20 ngaphambi kokudla. Kuyadingeka ukuguqula indawo yomjovo ngomjovo ngamunye. Kodwa-ke, ngokuya ngendawo yokuphatha isixazululo, ama-pharmacokinetics omuthi angashintsha, ngakho-ke ushintsho endaweni yokuphatha kufanele kuvunyelwane ngalo nodokotela.
Kuyadingeka ukunaka ubukhona be-cap. Lokhu kukhombisa ubuqotho be-vial. Azikho izinhlayiya okufanele zibe khona ngesixazululo, uketshezi kufanele lube sobala.
Lokhu okulandelayo kumele kucatshangwe:
- Lapho usebenzisa ikhambi nge-vial, sebenzisa isirinji efanelekile yepulasitiki.
- Okokuqala, umoya uqoqwa kwisirinji, inani lakhona elilingana nedosi yesisombululo. Faka esikhaleni esingenalutho ebhodleleni. Umthamo uphendulwe ngaphezulu. Isethi yesisombululo iyenziwa. Akufanele kube namabhamuza omoya kwisirinji. Kancane kancane faka ikhambi esikhunjeni sesikhumba esakhiwe yiminwe.
- Elebula udinga ukukhombisa usuku okwenziwa ngalo isethi yokuqala yemithi.
- Lapho usebenzisa ama-cartridges, ukusetshenziswa kwama-injector (amapeni wesirinji) kuyadingeka.
- I-cartridge inconyelwa ukuba ishiywe ekushiseni kwegumbi ihora elilodwa noma amabili, njengoba ukwethulwa kwento ebandisiwe kubuhlungu. Ngaphambi komjovo, susa umoya osele.
- I-cartridge ayikwazi ukugcwaliswa kabusha.
- Ngopeni wesirinji ongasebenzi, kuvunyelwe isirinji efanelekile.
Indlela eqondile yokuphatha yenziwa esibhedlela, njengoba izimo ezidingekayo zokubheka isimo sesiguli.
Ukuba khona kwezinsalela zesidakamizwa kwesinye isirinji akwamukeleki.
Imiphumela emibi Insuman Rapid GT
Umphumela ojwayelekile wecala ukwehla okubucayi kwenkomba ye-glucose. Imvamisa, lesi simo sikhula lapho umthamo we-insulin ungalandelwa. Iziqephu eziphindaphindwayo zivusa ukuthuthukiswa kokuphazamiseka kwemizwa. Izinhlobo ezinzima zezinkinga, ezihambisana nokukhishwa inyumbazana, ukuhlangana kokuthinteka kokunyakaza nokuqina, ziyingozi empilweni yesiguli. Kulezi zimo, ukulaliswa esibhedlela kuyadingeka.
Ngaphansi kokuqashwa kwabasebenzi bezokwelapha, izimpawu zimiswa ukusetshenziswa kwekhambi elihlanganisiwe le-dextrose noma i-glucagon. Izinkomba ezibalulekile zesimo se-metabolic, ibhalansi ye-electrolyte kanye ne-acid-base ratio ziqoqiwe. Izinga le-hemoglobin ye-glycosylated liyaqashwa.
I-Phenomena evela ekunciphiseni kweshukela entweni yobuchopho ingandulelwa yizibonakaliso zokusebenzisa amandla kwe-Reflex kwengxenye yohlelo lwezinzwa oluzimele. Ukwehla okukhulu kweglucose yegazi kungathinta ukugcotshwa kwe-potasium, okubangela i-hypokalemia ne-edema yamakhemikhali.
Umfutho wegazi ungancipha.
Engxenyeni yezitho zombono
Ukuguquguquka okumenyezelwe ekulawulweni kwe-glycemic kungaholela ekushikashikeni kwesikhashana kolwelwesi lweseli lwelensi yeso, ushintsho enkombeni yokuqamba kabusha. Ukushintshwa okubukhali kwezinkomba ngenxa yokwanda kokuqina kwezokwelapha kungahle kuhambisane nokuwohloka kwesikhashana kwesimo se-retinopathy.
Kwi-hypoglycemia enzima ne-prinopathy ekhulayo, ukulimala kwe-retina noma i-optic nerve yemvelo yesikhashana kungenzeka.
Izitho zeHematopoietic
Kwesinye isikhathi ngesikhathi sokwelashwa, ama-antibodies entweni angaqala ukukhiqizwa. Kulokhu, ukulungiswa komthamo kuyadingeka.
Engxenyeni yesikhumba
Esizeni somjovo, ukuthuthukiswa kwe-pathologies yezicubu ze-adipose, ukuncipha kokufakwa kwendawo kwalokhu, kungenzeka.
Ukuluma, ubuhlungu, ubomvu, isifuba, ukuvuvukala, noma ukuvuvukala kungavela endaweni yomjovo.
Ngasohlangothini lwe-metabolism
Ukuphazamiseka okungenzeka kwe-sodium metabolism, ukubambezeleka kwayo emzimbeni kanye nokuvela kwe-edema.
Allergies
Ukuphendula kwesikhumba, i-bronchospasm, i-angioedema, noma ukushaqeka kwe-anaphylactic kungenzeka.
Umthelela ekhonweni lokulawula izindlela
Izinkinga zokwelashwa zingaholela ekunakekelweni kokunaka kokuncipha, ukwehla kwezinga lokuphendula. Lokhu kungaba yingozi lapho ushayela imishini nezimoto.
Imiyalo ekhethekile
Ayikwazi ukusetshenziswa kumaphampu nge-silicone tubing.
Sebenzisa ebudaleni
Ezigulini ngemuva kweminyaka engu-65 yobudala, ukusebenza kwezinso kuyancipha. Lokhu kufaka ukwehla kwenani elidingekayo le-insulin.
Isabelo sezingane
Lapho welapha izingane, kukhethwa ngokucophelela umthamo ngoba isidingo se-insulin singaphansi kunabantu abadala. Ukuvimbela ukuthuthukiswa kwe-hyperglycemia enzima, i-glucose iyabhekwa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngesikhathi sokukhulelwa nangemva kokuzalwa kwengane, ukwelashwa akumiswa. Ukulungiswa kwerejimeni yokwelashwa nomthamo kungadingeka ngenxa yezinguquko ezidingweni ze-insulin.
Isicelo sokusebenza kokulimala kwezinso
Njengomphumela wokwehliswa kwezinqubo ze-metabolic nge-insulin emzimbeni, isidingo sale nto siyancipha.
Sebenzisa umsebenzi wesibindi okhubazekile
Amandla wokuqamba ushukela kusuka ekwakhiweni okungelona i-carbohydrate uyancipha. Lokhu kunganciphisa isidingo sento ethile.
Ukweqisa kwe-Insuman Rapid GT
Ukuphatha okweqile kwesidingo somzimba semithamo ye-insulin kuholela ekuthuthukisweni kwe-hypoglycemia.
Ukuxhumana nezinye izidakamizwa
Ukuthatha umuthi ngesikhathi sokwelashwa kwe-insulin kufanele kuhambisane nodokotela wakho.
Ukuthatha umuthi ngesikhathi sokwelashwa kwe-insulin kufanele kuhambisane nodokotela wakho.
Inhlanganisela ehlanganisiwe
Inhlanganisela yomuthi ne-insulin yezilwane nama-analogue ayihlanganisiwe.
Ukuphathwa okuhlangene kwePentamidine kuholela ekwakhiweni kwezinkinga.
Akuhlanganisiwe ukuhlanganisa
Izinto ezilandelayo kanye namalungiselelo enza buthaka umphumela wokwehlisa ushukela:
- ama-corticosteroids;
- i-adrenocorticotropic hormone;
- okususwayo kwe-phenothiazine ne-phenytoin;
- i-glucagon;
- ama-hormone ocansi abesifazane;
- ukukhula kwehomoni;
- i-nicotinic acid;
- phenolphthalein;
- okokugcoba
- izidakamizwa ezicindezela uhlelo lwezinzwa;
- zokwenziwa androgen Danazole;
- umuthi olwa ne-TB i-Isoniazid;
- adrenoblocker Doxazosin.
I-Sympathomimetics kanye ne-iodinated tyrosine derivatives yenza buthaka isenzo sesisombululo.
Yehlisa amandla okwehlisa ushukela Umuthi olwa ne-TB i-Isoniazid.
Inhlanganisela edinga ukuqashelwa
Le mithi elandelayo ikhulisa ubungozi bezinkinga:
- ama-endrogens nama-anabolics;
- inani lezidakamizwa zokwelapha ukuphazamiseka kwenhliziyo nemithambo yegazi;
- Izikhuthazi ze-CNS;
- i-antiarrhythmic izidakamizwa cybenzoline;
- i-propoxyphene analgesic;
- i-pentoxifylline angioprotector;
- i-cytostatic drug trophosphamide;
- inani labacindezeli;
- ama-sulfonamides;
- imithi eminingana ehlose ukwehlisa i-cholesterol;
- imishanguzo ye-tetracycline;
- amalungiselelo asuselwa ku-somatostatin kanye nama-analogues ayo;
- ama-hypoglycemic agents;
- isifiso sokudla fenfluramine;
- antitumor izidakamizwa ifosfamide.
Ukuqapha kudinga ukuthatha umuthi osuselwa kuma-esters e-salicylic acid, tritokvalin, cyclophosphamide, guanethidine ne-phentolamine.
Usawoti weLithium ungabamba noma uthuthukise umphumela wesidakamizwa. I-Reserpine ne-clonidine ziyehluka ngesenzo esifanayo.
Ukusetshenziswa kwe-beta-blockers kwandisa ubungozi bezinkinga.
Ukuhambisana notshwala
E-alcoholic engapheli, izinga le-glycemia liyashintsha. Ngesifo sikashukela, ukubekezelela utshwala kuyancishiswa, futhi nokubonisana nodokotela kuyadingeka ukuze uthole imithamo yotshwala ephephile. Ukugxilwa kwe-glucose kungadonsela ezingeni elibucayi.
Ama-Analog
I-insulin yomuntu iqukethe izidakamizwa ezifana ne-Insuran, Actrapid, Humulin, Rosinsulin, Biosulin, njll.
Imibandela yekhefu lekhemisi
Akuyona uhlu lwezidakamizwa ezisemakethe yamahhala.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kukhululwa lapho kwethulwa iresiphi.
Intengo ye-Insuman Rapid GT
Izindleko ezijwayelekile zokupakishwa ngama-ruble ayi-1000-1700.
Izimo zokugcina zomuthi
Umbuso wokushisa wokugcina umuthi ngu + 2 ... + 8 ° C. Musa ukuncika esitsheni eceleni kwezindonga zesiqandisi ukuze ungaholi ikhambi.
Ngemuva kokusetshenziswa kokuqala, ibhodlela lingagcinwa amahora ama-4, i-cartridge - ngezinsuku ezingama-28 ngemuva kokufakwa. Ngesikhathi sokulondolozwa, ukubonakaliswa kokukhanya kufanele kugwenywe futhi amazinga okushisa akufanele avunyelwe ukuba akhuphuke ngaphezulu kwe-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Kusukela ngosuku lokukhiqiza, ikhambi lilungele ukusetshenziswa iminyaka emi-2.
Umkhiqizi
Umuthi wenziwa ngabakwaSanofi-Aventis. Izwe lokukhiqiza lingaba yiJalimane noma iRussia.
Ukubuyekezwa mayelana ne-Insuman Rapid GT
UVasily Antonovich, udokotela obambelela endocrinologist, eMoscow: "Kwabhekwa kakhulu imijovo enesixazululo. Lesi sidakamizwa sinokuphepha okwanele nokubekezelelana okuhle."
UDaria, oneminyaka engama-34, uSeverodvinsk: "Ezinye izidakamizwa zisize kakhulu kuneRapid. Ngenxa yemijovo, ngikwazile ukuqinisa izinga likashukela wami.
UMarina, oneminyaka engama-42, uSamara: "Uma welapha izingane, kubalulekile ukubonana nodokotela ngezimpawu zokweqisa, ukuqapha izinga lezinkomba. Njengokwelashwa kwe-insulin, umuthi unikezwe indodana, ikhambi elihle."
