Leli thuluzi lisetshenziselwa i-mellitus engavikelekile nge-insulin. Umuthi usiza ukujwayeza ukujwayeza ushukela egazini. Isithako esisebenzayo siqinisa isisindo sokukhuluphala bese sinciphisa i-LDL.
Igama Lezwe elingafanele
I-Metformin
I-Metfogamma 1000 isiza ekulinganiseni i-glucose egazini.
I-ATX
A10BA02
Khipha amafomu nokwakheka
Umenzi ukhiqiza umuthi ngesimo samathebulethi, avikelwe yikhova lefilimu. Ukuqanjwa kuqukethe i-1000 mg ye-metformin. Umkhiqizo uqukethe ne-povidone, i-hypromellose, i-magnesium stearate. Ku-blister pack yamathebhulethi ayi-10 noma ayi-15. Izingcezu ezingama-30 noma eziyi-120 iphakethe ngalinye.
Isenzo se-Pharmacological
Isithako esisebenzayo sivimbela ukwakheka kwe-glucose kusuka kumakhemikhali angenawo ama-carbohydrate esibindini, futhi kuvimbela ukufakwa kweglucose esiswini. Ithuluzi linciphisa inani le-cholesterol embi egazini futhi luthuthukisa ukumuncwa kweglucose yizicubu zomzimba. Ngemuva kokuphathwa, umzimba uba nozwela kakhulu nge-insulin. Ngaphezu kwalokho, umkhiqizo uvama ukukhuluphala ngokweqile futhi ukhuthaza ukuhlanganiswa kabusha kwezigaba zegazi ezintsha.
I-Pharmacokinetics
Ukungeniswa ngokushesha kusuka kwipheshana lesisu. Empeleni ayixhumeki ngamaprotheni. Not biotransformed emzimbeni. I-metformin ku-plasma ifinyelela phezulu ngemuva kwamahora ama-2. Kukhishwa engxenyeni yomchamo kusuka emahoreni amabili kuya kwayi-5. Inganqwabelana kwezicubu zomzimba ngokusebenza kokulimala kwe-renal.
Izinkomba zokusetshenziswa
Umuthi wenzelwe ekwelashweni kwesifo sikashukela sohlobo 2. Isiza ukunciphisa isisindo. Kusetshenziswa ekwelapheni kweziguli ezingenawo umkhuba wokukhulisa imizimba ye-ketone egazini.
Contraindication
Umuthi uphulwe kwezinye izimo:
- ukungabekezeleli izingxenye zomuthi;
- izingane ezingaphansi kweminyaka engu-18;
- ukwephulwa kwemisebenzi yobuchopho yemvelaphi yemithambo yegazi;
- ukugcwala okukhulu kwe-glucose kanye nemizimba ye-ketone egazini;
- isimo sikashukela esimnandi noma ukoma;
- umsebenzi okhubazekile we-renal kanye we-hepatic;
- ukukhulelwa
- ukuncelisa;
- infarction myocardial esigabeni esibuhlungu;
- i-lactic acidosis kanye nezimo zayo ezicasulayo, kufaka phakathi ukusetshenziswa kabi kotshwala;
- ukwephula ibhalansi elenziwa ngamanzi emzimbeni.
Umuthi okukhulunywa ngawo awubekelwe ukuphefumula nokuhluleka kwenhliziyo.
Umuthi awunqunyelwe ukuphefumula kanye nokwehluleka kwenhliziyo.
Ungayithatha kanjani iMetfogamma 1000
Amathebulethi athathwa ngomlomo ngesidlo, ahlanzwa ngenani lamanzi adingekayo.
Ngoshukela
Umthamo onconyiwe uvela ku-500 mg kuya ku-2000 mg. Awuthathe amaphilisi angaphezu kuka-3 ngosuku. Imithamo ephezulu kakhulu ayithinti ukusebenza kahle kokwelashwa. Udokotela angalungisa umthamo ngokuya ngesimo sesiguli nezifo ezihlobene naso.
Imiphumela emibi yeMetphogamm 1000
Umuthi ngesikhathi sokwelashwa ungadala imiphumela emibi ehlukahlukene ezivela kwizitho nezinhlelo.
Amapheshana wesisu
Ubuhlungu esiswini, ukugabha, izitulo ezikhululekile, ukunambitheka kwensimbi emlonyeni, ukulahleka kwesifiso.
Izitho zeHematopoietic
Kwesinye isikhathi kubangela i-folic acid defence anemia.
I-Metphogamma 1000 ibangela i-anemic acid yokuntuleka kwe-anemia.
Isistimu yezinzwa ephakathi
Ukuthuthumela, ubuthakathaka, ikhanda, isiyezi, ukujuluka okuphezulu.
Kusuka ohlelweni lwezinhliziyo
Inani lamaseli egazi liyancipha.
Uhlelo lwe-Endocrine
Ukusetshenziswa isikhathi eside kuholela ekufakweni kokulimazeka kwevithamini B12.
Ngasohlangothini lwe-metabolism
Ukwehla kokuxineka kwe-glucose egazini kuya kumanani abucayi (ngaphansi kuka-3.3 mmol / L), ukubonakala kwe-lactic acidosis.
Allergies
Ubomvu besikhumba ngenxa yokwanda kwama-capillaries, ukulunywa kanye nokuqina.
Umuthi ungadala ukulunywa kanye nokubomvu.
Umthelela ekhonweni lokulawula izindlela
Umuthi ungaba nemiphumela emibi ethile. Ngokuhlanganiswa neminye imithi ye-hyperglycemia, umuthi ungaholela ku-hypoglycemia (isiyezi, ikhanda elibi, ukungakwazi ukugxila, i-malaise ejwayelekile). Ngesikhathi sokwelashwa, kungcono ukushayela izimoto ngokuqapha.
Imiyalo ekhethekile
Ukuvimbela ukuvela kokuphikiswa okuvela emgudwini wesisu, umthamo kumele unyuswe kancane kancane. Ngokuvela kwe-lactic acidosis (ukugabha, isicanucanu, ubuthakathaka), ukwelashwa kuyekwa.
Lo mkhiqizo womlomo akufanele usetshenziswe lapho kunezifo ezithathelanayo kanye nokulimala kanzima.
Yekani ukuthatha umuthi ezinsukwini ezi-2 ngaphambi kokuhlinzwa okuhleliwe. Ungaqala ukuthatha izinsuku ezi-2 ngemuva kokuhlinzwa.
Uma ubuhlungu bemisipha kwenzeka, kuyadingeka ukuthi kwenziwe izivivinyo zokuqukethwe kwe-lactic acid emapulini wegazi. Ngesikhathi sokwelashwa, kuyadingeka ukuqapha ukusebenza kwe-renal, ukukala ukuqoqwa kwe-creatinine ku-serum noshukela ngokuvama okuncane.
Uma izinhlungu zemisipha zenzeka ngemuva kokuthatha iMetfogamma, udinga ukuthatha izivivinyo zokuqukethwe kwe-lactic acid ku-plasma yegazi.
Akunconyelwe ukusebenzisa umuthi ezigulini ezilandela ukudla noma ezingondlekile kahle (ekudleni okungaphansi kwe-1000 kcal / ngosuku).
Iziguli ngemuva kweminyaka engu-60 yobudala bomzimba osindayo azinconywa ukuthatha umuthi. Ingozi yokwanda kwe-lactic acidosis iyanda.
Sebenzisa ebudaleni
Kumele kuthathwe ngokuqapha. Ekwaluphaleni, umthamo kufanele ungeqi ku-1000 mg ngosuku.
Isabelo sezingane
Ukuthi umuthi usebenza kangakanani ebuntwaneni akwaziwa. Abantu abangaphansi kweminyaka eyi-18 bayalwa ukuba bayeke ukuyithatha.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Thatha umuthi kulezi zikhathi u-contraindified.
Thatha umuthi okukhulunywa ngawo ngesikhathi sokukhulelwa uvunyelwe.
Isicelo sokusebenza kokulimala kwezinso
Sebenzisa umuthi uma kwenzeka ukhubazeka kabi kwe-renal.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukusetshenziswa ezimweni ezinzima zesibindi kuyaphikiswa.
I-overdose yeMetfogamma 1000
Nge-overdose, i-lactic acidosis iyenzeka. Iphathwa ngokuhlanzwa kwegazi okungeziwe (hemodialysis).
Ukuxhumana nezinye izidakamizwa
Ukuthatha i-sulfonylurea, i-Acarbose, i-insulin, izidakamizwa ezingezona i-steroidal ezilwa nokuvuvukala, ama-inhibitors we-MAO, i-Oxetetracycline, i-ACE inhibitors, okuphuma kuClofibrate, i-Cyclophosphamide ne-B-blockers kuholela ekwandeni komthelela wokunciphisa ushukela.
Umphumela wesidakamizwa wehliswa amandla ngokusetshenziswa kanyekanye kwe-glucocorticosteroids, izindlela zokuvimbela inzalo ngomlomo, i-adrenaline, izidakamizwa ze-adrenomimetic, ama-hormone egilo, i-thiazide ne-loop diuretics, ama-hormone aphikisayo esenzweni ku-insulin, i-phenothiazine derivatives ne-nicotinic acid.
Umphumela we-metfogamma ufiphele amandla ngokusetshenziswa kanyekanye kwama-glucocorticosteroids.
INifedipine ithuthukisa ukumuncwa kwe-metformin. I-Cimetidine yehlisa izinga lokuqedwa kwezidakamizwa futhi lokhu kuholela ku-lactic acidosis. Uma kunesidingo, ungaphuza izidakamizwa ze-insulin nezokwelapha ezibangelwa ukuqashwa kukadokotela. I-Metfogamma 1000 inciphisa ukusebenza kwezidakamizwa ezivimbela i-thrombosis.
Ukuhambisana notshwala
Umuthi awusetshenziswa ngokuhlangana notshwala. Uphuzo oludakayo lukhulisa ubungozi bokuqhamuka nezimo ze-hypoglycemic.
Ama-Analog
Ekhemisi, ungathenga izidakamizwa ezifanayo:
- I-Bagomet;
- I-Glycometer;
- IGlucophage;
- I-Glumet;
- I-Dianormet;
- I-Diaformin;
- Methamine;
- I-Metformin;
- Mepharmil;
- Panfort Wed;
- Sinjardi;
- Siofor.
Ngaphambi kokufaka esikhundleni se-analogue, kufanele ubonane nodokotela futhi uhlolwe.
Imibandela yekhefu lekhemisi
Umuthi usatshalaliswa ngugqirha.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ungadedeli ngaphandle kwencwadi kadokotela.
Izindleko
Intengo e-Ukraine - kusuka ku-150 UAH, eRussia - kusuka kuma-ruble ayi-160.
Izimo zokugcina zomuthi
Amathebulethi kufanele agcinwe emaphaketheni awo okuqala kumazinga okushisa afinyelela ku- + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emi-4
IMetfogamma 1000 inegama elifanayo elithi Metformin, eligcinwa emazingeni okushisa afinyelela ku- + 25 ° C.
Umkhiqizi
Dragenopharm Apotheker Püschl GmbH & Co KG, eJalimane.
Ukubuyekezwa
UNikolai Grantovich, oneminyaka engama-42 ubudala, uTver
Umuthi uhloselwe ukuvimbela i-gluconeogeneis. Kubhekana noshukela omkhulu wegazi. Imiphumela emibi ayivelakancane uma ulandela imiyalo.
UMarina, oneminyaka engama-38, u-Ufa
Ngiphethwe yisifo sikashukela sohlobo 2 futhi ngihlushwa isisindo ngokweqile. Njengoba kushiwo ngudokotela, uDiaformin wasetshenziswa, kepha akakwazanga ukubhekana nemisebenzi yakhe. Ngemuva kokuthatha iMetfogamma, imizwa ingcono kakhulu. Ushukela wegazi uzinze futhi kwakungekho i-hypoglycemia.
UVictoria Asimova, oneminyaka engama-35, u-Oryol
I-endocrinologist yanquma ikhambi lokukhuluphala ngokumelene nesifo sikashukela i-mellitus. Amaphilisi athuthukisa imetabolism. Izinsuku ezimbili zokuqala kwakuyizitulo ezikhululekile. Izimpawu zanyamalala ngokushesha. Kwakungenzeka ukuthi ulahlekelwe ama-9 kg, wenze ngokwejwayelekile i-glucose futhi uthuthukise isimo esivamile. Ngijabule ngomphumela.
