I-Diaformin isidakamizwa se-antihyperclimatic spectrum yesenzo, esetshenziselwa ukwehlisa ukugcwala kwe-glucose egazini ezigulini ezinesifo sikashukela i-mellitus.
Igama Lezwe elingafanele
I-Metformin.
I-Diaformin isetshenziselwa ukwehlisa ushukela wegazi ezigulini ezinesifo sikashukela.
I-ATX
A10BA02 - Metformin.
Khipha amafomu nokwakheka
Ithebula le-500 ne-850 mg lesithako esisebenzayo - metformin hydrochloride. Izakhi ezisizayo ekwakhiweni kwazo isitashi samazambane, i-magnesium stearate, i-microcrystalline cellulose, i-povidone.
Isenzo se-Pharmacological
I-ejenti ye-hypoglycemic eyehlisela i-glucose yegazi ezigulini ezinesifo sikashukela ngaphandle kwengozi yokuthola i-hypoglycemia ayithinti ukucekelwa phansi kwe-insulin.
Umgomo wesidakamizwa ukwandisa ukubonwa kwe-insulin ngama-peripheral receptors kanye nokusheshisa inqubo yokusetshenziswa kwe-glucose ezingeni lamaselula. Umuthi wehlisa izinga lokufakwa kwe-carbohydrate ngama-mucous membrane wesistimu yokugaya ukudla, ithuthukisa inqubo ye-lipid metabolism, yehlise izinga le-cholesterol embi.
I-Diaformin yehlisa izinga lokufakwa kwe-carbohydrate ngama-mucous membranes wesistimu yokugaya ukudla.
I-Pharmacokinetics
Into esebenzayo igxilwe ngamandla emgudwini wesisu. Izinga le-bioavailability lisuka ku-50% liye ku-60%. Awubandakanyeki ku-biomodification.
Ukuphuma emzimbeni kuthathwa kungashintshiwe ngokusebenzisa izinso ngomchamo, cishe u-30% wawo wonke umthamo udonswa emgodini. Ngasikhathi sinye, ukudla okubandayo kuhamba kancane. Ingxenye esemqoka iyakwazi ukuqongelela izicubu. Ukuxhumana namaprotheni e-plasma akukho.
I-Half-life yenziwa ngemuva kwamahora we-9-12, uma kukhona isifo sezinso, inqubo iyashesha.
Izinkomba zokusetshenziswa
Kusetshenziswa ekwelapheni i-mellitus yesifo sikashukela sohlobo oluncike ku-insulin, lapho kungenakwenzeka ukufeza impendulo enhle ekudleni. Umuthi unqunyelwe abanesifo sikashukela abanesisindo somzimba ngokweqile kanye nokukhuluphala, noma ngentuthuko yokumelana komzimba nezidakamizwa zeqembu le-insulin.
Ekwelashweni kwesifo sikashukela kunikeza umphumela omuhle wokwelapha, ngokuya ngokudla ne-insulin.
Ukwelashwa kwesifo sikashukela sohlobo 2 ngaphandle kwemithi - kungenzeka lokhu?
Uyini umehluko phakathi kwe-Amoxiclav neFlemoxin Solutab? Funda ngakho esihlokweni.
Kuyini ukusetshenziswa kwensiza yesifo sikashukela?
Contraindication
Ukuphulwa okuphelele, lapho okwamukelwa khona i-Diaformin kunqatshelwe ngokwezigaba:
- i-precoma;
- ketoacidosis;
- isimo sokukhubazeka kwesifo sikashukela;
- ukwephulwa kokuhlunga kwe-glomeruli ye-renal;
- ukungasebenzi kahle kwesibindi;
- ukomisa;
- umkhuhlane;
- i-hypoxia ebangelwa i-sepsis;
- izifo ezithathelwanayo ezithinta umzimba (umkhuhlane);
- ukuba khona kwe-lactic acidosis;
- ukungabekezelelani komuntu ngamunye kwizakhi ezithile.
Ukuqokwa kweziguli ezinomlando wezifo ezingamahlalakhona ezibangelwa ukwanda ngezikhathi ezithile kukhishwe ngaphandle. Ayibekelwe futhi abantu okuthi, ngenxa yezizathu zokwelashwa, abalandele ukudla ngenani elilinganiselwe lama-carbohydrate.
Ngokunakekela
Akunconyelwe abantu abenze ukungenelela okuyinkimbinkimbi kokuhlinzwa, balimele kakhulu. Okunye ukwephulwa okuhlobene nokuba khona kokwehluleka okulinganiselayo kwezinso okulinganiselayo, uphuzo oludakayo. I-ejog ye-hypoglycemic ayiboniswa kwiziguli ezinomsebenzi wobungcweti ohambisana nokuzivocavoca umzimba okwenziwa njalo.
Ungayithatha kanjani i-Diaformin?
Umthamo wesidakamizwa kanye nesikhathi sokwelashwa sinqunywe ngudokotela. Umthamo onconyiwe kubantu abadala ekuqaleni kokwelashwa ngu-500-1000 mg ngosuku. I-umthamo wokwelapha wokulungiswa ngu-1500-2000 mg ngosuku. Inani elikhulu ngosuku alikho ngaphezulu kuka-3000 mg. Umthamo wansuku zonke obekiwe uhlukaniswe ngemithamo eminingana (ukusuka 2 kuya ku-3). Amathebulethi athathwa ephelele ngokudla noma ngokushesha ngemuva kwalokho.
Amathebulethi e-Diaformin athathwa ephelele ngokudla noma ngokushesha nje.
Ngoshukela
Ukwelashwa kwesifo sikashukela sohlobo 2 sohlobo oluzimele se-insulin kwenziwa ngomthamo we-Diaformin kusuka ngo-1500 kuya ku-2000 mg. Ezimweni ezimbi kakhulu, kuvunyelwe ukudla okwenziwa nsuku zonke okungama-3000 mg.
Imiphumela emibi
Izimpawu ezivame ukuhlangana nazo ezigulini zifaka isicanucanu nokuhlanza, ubuhlungu besisu, ukulahlekelwa yinhliziyo, nohudo. Le Symbomatology idlula ngokuzimela. Uma kwenzeka, udinga ukunciphisa umthamo womuthi noma ushintshe isikhathi sokuphathwa kwawo.
Okunye ukusabela okungekuhle:
- Uhlelo lokugaya ukudla: ukuthuthukiswa kokuqina kwezinso, i-hepatitis.
- Isikhumba: i-erythema, ukuqubuka, ukulunywa. Akuvamile - urticaria.
- Isistimu yezinzwa ephakathi: ukuhlanekezela kombono wokunambitha.
- I-Metabolism: ukuthuthukiswa kwe-hypovitaminosis B12. Ukuntuleka kwevithamini leSerum kubonwa ikakhulu kubantu abane-anemia.
Ngemuva kokuthatha i-Diaformin, kubuhlungu esiswini kungenzeka.
Umthelela ekhonweni lokulawula izindlela
Akunemikhawulo ekushayeleni, njengoba umuthi awusithinti kabi isistimu yezinzwa ephakathi.
Imiyalo ekhethekile
Izifo zezinso noma isibindi ngenkambo ebucayi ngenkathi kusetshenziswa i-Diaformin kungadala ukukhula kwe-lactic acidosis. Umuthi kufanele uthathwe ngokuqapha ngokweqile ezigulini, ngenxa yokuxineka kwezinso, zelashwa nge-diuretics, izidakamizwa ezingezona neze-steroidal ezilwa nokuvuvukala.
Uma lesi simo siba sibi ngokwanda kwezimpawu ezinjengokuthi uhudo isikhathi eside, ukomisa, ukugabha njalo, nokuthatha umuthi we-hypoglycemic, kubalulekile ukuwuyeka okwesikhashana.
Izici zobungozi zokuvela kwe-lactic acidosis yi-ketosis, ukungagodli isikhathi eside ekudleni, ukusetshenziswa njalo kotshwala, i-hypoxia.
Umuthi kufanele ukhanseliwe ezinsukwini ezi-2 ngaphambi kokungenelela kokuhlinzwa okuhleliwe. Ukuqalwa kabusha kwemithi kungenzeka ezinsukwini ezi-2 ngemuva kokuhlinzwa.
Umuthi kufanele ukhanseliwe ezinsukwini ezi-2 ngaphambi kokungenelela kokuhlinzwa okuhleliwe.
Ngesikhathi sokwelashwa, kuyadingeka ukunamathela ekudleni okunokusabalalisa okufanayo kwama-carbohydrate ekudleni. Iziguli ezikhuluphele kufanele zilandele ukudla. Ezimweni ezinzima, ukunciphisa umzimba kuyadingeka.
Kwenqatshelwe ukuthatha lesi sidakamizwa ezigulini ezinokwehluleka okukhulu kwenhliziyo. Ngomusa omncane kuya kwesilinganiso esiphakeme, ukwelashwa kwe-Diaformin kufanele kwenziwe kuphela ngaphansi kwesimo sokuqapha njalo isimo somsipha wenhliziyo.
Esehlulekeni kwe-renal, lapho izinga le-creatinine likububanzi obungu-45 kuye ku-60 ml ngomzuzu, ukuthatha i-hyperglycemic ejenti kumele kukhanseliwe ezinsukwini ezi-2 ngaphambi kokuhlolwa nge-X-ray kusetshenziswa umenzeli ophikisayo. Ukwelapha kuqala emuva kwezinsuku ezi-2.
Sebenzisa ebudaleni
Kubantu abangaphezu kweminyaka engama-65, ikhambi lingaholela ekungasebenzi kahle kwezinso. Umthamo ukhethiwe ngokuya ngemiphumela yezifundo zesimo kanye nokusebenza kwezinso.
Kubantu abangaphezu kweminyaka engama-65, ikhambi lingaholela ekungasebenzi kahle kwezinso.
Isabelo sezingane
Inqunyelwe izingane ezinesifo sikashukela kusuka eminyakeni eyi-10. Isilinganiso esiphakanyisiwe umthamo ngu-500-850 mg. Udinga ukuphuza amaphilisi ama-1 isikhathi ngosuku ngemuva kokudla noma ngaphambi kokudla main.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kukhishwe.
Ukweqisa
Ukusetshenziswa okukodwa kumthamo ongaphezu kwama-85 mg kuholela ekubonakaleni kwe-hypoglycemia, i-lactic acidosis enesithombe esibonisa uphawu - umkhuhlane, izinhlungu nokuqaqamba kwemisipha nokuhlangana, ubuhlungu besisu nesisu, ukuphefumula komoya, isiyezi, ukungazi kahle kahle.
Usizo nge-overdose - ukunqamuka ngokushesha kwemithi nokwelashwa esibhedlela yisiguli.
Ukususa umuthi omningi emzimbeni, ukwelashwa okubonakalayo kwenziwa. Ukwenza isimo sibe ngokwejwayelekile, kunqunywa i-hemodialysis.
Ukulungisa isimo sesiguli ngokwejwayelekile nge-overdose ye-Diaformin, kunikezwa i-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Ukuhlanganiswa neDanazol kungavusa i-hyperglycemia.
Ingozi ye-lactic acidosis inyuka ngokusetshenziswa okuhlanganisiwe kwezidakamizwa ezine-ethanol ekwakhiweni, i-diuretics.
I-Chlorpromazine inciphisa ukugcinwa kwe-insulin futhi ikhuphule ukugxila kwe-glucose.
Ukuhambisana notshwala
Ayihambelani.
Ama-Analog
Izidakamizwa ze-Hypoglycemic ezinesibonisi esifanayo nenqubo yokusebenza: I-Glucofage, i-Diaformin OD ne-SR, Metformin, Metamine.
Izimo zeholide Diaformina ekhemisi
Ngokusebenzisa umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Akunakwenzeka.
Intengo ye-Diaformin
Izindleko - kusuka kuma-ruble ayi-150. (IRussia) noma i-25 UAH. (E-Ukraine).
Izimo zokugcina zomuthi
Iphakethe lethebhulethi kufanele ligcinwe ekushiseni kuka + 18 ° kuya ku- + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
IDiaformin inegama lomhlaba wonke elingahambisani neMetformin. Umuthi ulungele ukusetshenziswa iminyaka emi-3.
Umkhiqizi Diaformina
E-OZON, eRussia
Ukubuyekezwa mayelana ne-Diaformin
UKsenia, oneminyaka engama-42, u-Orel: "Ngemuva kwesonto ephuze amaphilisi, kwavela isicanucanu, kwakukhona nokuhlanza, kanti nokudla kwakulahlekile. Ekuqaleni ngacabanga ukuthi imiphumela emibi ihlobene nokuhlinzwa ngemuva kwe-gynecological. Bengicabanga ukuthi kufanele ngiyeke ukuphuza umuthi, kepha kwavela ukuthi imiphumela emibi ibangelwa ukuthi ngawaphuza ngokungafanele amaphilisi. Ngathi nje ngiqala ukuwaphuza masisha ngemuva kokudla, konke kwahamba. "
U-Alevtina, oneminyaka engu-51, uSakhalin: "Sekuphele iminyaka engu-3 ngithatha amaphilisi eDiaformin. Kuze kube manje, lesi isidakamizwa esihle kakhulu, futhi ngazama eziningi sazo. Akubangeli ukusabela okungekuhle, uma kuthathwe ngokufanele. Umehluko kwezinye izidakamizwa ukuthi kungenzeka ukuthi i-hypoglycemia incane, kepha into esemqoka ukuthi Ukudla okunama-carbohydrate olinganiselayo. "
U-Andrei, oneminyaka engama-61, eMoscow: "Ngayiqala le nkinga ngiphumelelile. Ngokobufakazi, bekufanele ngiphuze umthamo ka-3000 mg, kodwa ngemuva kwezinsuku ezimbalwa ikhanda lami laba buhlungu kakhulu, isicanucanu nokuhlanza kwavela, isisu sami sasihlala sibuhlungu. udokotela ulungise umthamo, awuhlisela ku-2000 mg, isimo sabuyela esimweni esijwayelekile. Ngemuva kwenyanga, umthamo wenyuselwa ku-2500 mg. Konke kwakuhamba kahle. Uma ubala kahle inani lezidakamizwa, liyabekezelelwa kahle. Kimina, le ngenye yezindlela eziphumelela kakhulu ekwelashweni kwesifo sikashukela. "
