Umuthi i-Amoxiclav 125: iziyalezo zokusetshenziswa

I-Amoxiclav iyi-antibiotic yeqembu lama-penicillin wemvelaphi ye-semisynthetic, ehlanganiswe ne-beta-lactamitase inhibitors. Inemiphumela ehlukahlukene. Ikhiqizwa yinkampani yezemithi yaseSlovenia.

I-ATX

J01CR02.

I-Amoxiclav iyi-antibiotic yeqembu lama-penicillin wemvelaphi ye-semisynthetic, ehlanganiswe ne-beta-lactamitase inhibitors.

Khipha amafomu nokwakheka

I-Amoxiclav inezinhlobo ezi-2 zokukhishwa: amaphilisi okubanjiswa ngamafilimu kanye ne-powder. Amathebulethi angaqukatha izinto ezisebenzayo i-amoxicillin trihydrate nosawoti we-potassium we-clavulanic acid ngamanani alandelayo:

• 250 no-125 mg;
• 500 no-125 mg;
• 875 no-125 mg;

Powder

I-Amoxiclav 125 isesimweni sempuphu esetshenziselwa ukulungisa ukumiswa, okufanele ithathwe ngomlomo. Lapho buhlanjululwe, kutholakala amalungiselelo aqukethe ama-5 ml:

• i-amoxicillin trihydrate - 125 mg;
• usawoti we-potassium we-clavulanic acid - 31.25 mg.

Kumakhemisi, umuthi ungena ngamabhodlela engilazi amnyama anomthamo we-100 ml, ngalinye liqukethe u-25 g we-powder. Amabhotela afakwe isipuni sokulinganisa noma i-pipette futhi abekwe emabhokisini amakhadibhodi.

Amathebulethi e-Amoxiclav aqukethe i-amoxicillin trihydrate nosawoti we-potassium we-clavulanic acid.

I-Amoxiclav 125 isesimweni se-powder yokumiswa, okufanele ithathwe ngomlomo.

Emakhemisi, umuthi ungena ngamabhodlela engilazi amnyama anomthamo we-100 ml.

Ngaphezu kwalokho, umenzi unikeza izimpuphu ezinikeza ukugxila okulandelayo kwezinto ezisebenzayo ku-5 ml wokumiswa kokuqeda:

• 250 no-62,5 mg;
• 400 no-57 mg;
• 500 no-100 mg;
• I-1000 ne-200 mg.

Isenzo se-Pharmacological

Isenzo salo muthi sihlose ukuvimbela ukwenziwa kabusha kwamagciwane kanye nokubhujiswa kwamakoloni awo. Lo mphumela wokwelapha ubangelwa ukufakwa kokubumbana kwe-semisynthetic penicillin emithini, kanye ne-clavulonic acid, okuthi ngaphezu komsebenzi wayo oyinhloko - ukuvikela i-amoxicillin emiphumeleni ye-beta-lactamis ekhiqizwa ngama-pathogens - inomsebenzi wayo wokulwa nokwelapha.

Lo muthi uyasebenza ngokuqhathanisa:

• i-aerobic gram-positive bacteria ama-streptococci, staphylococci, enterococci, njll., ngaphandle kwama -organic amancane akhombisa ukumelana ne-methylcyllin;
• ama-aerobic gram-negative strains, njenge-salmonella, iHelicobacter pylori, namanye ama-pathogens amaningi;
• amakoloni we-anaerobic gram-positive kanye ne-gram-negative microorganisms.

I-Amoxiclav iyasebenza ngokulwa neHelicobacter pylori.

I-Pharmacokinetics

Zombili izakhi ezisebenzayo zomuthi zisatshalaliswa ngokushesha ezicutshini, zitholakala kulamanzi e-pleural and synovial fluid, emaphashini, njll, kepha zingangeni emgomeni wobuchopho begazi lapho kungekho ukuvuvukala kokulimala kwemithambo.

Ukuqedwa kwesiqongo kufinyelelwa ihora elilodwa ngemuva kokuphathwa ngomlomo, impilo yesigamu ngamahora ayi-1-1,5. Zombili izinto ezisebenzayo zidlulwa ikakhulukazi yizinso.

Izinkomba zokusetshenziswa

I-Amoxiclav iboniswa:

• ukutheleleka kwezitho ze-ENT, ipheshana lokuphefumula elingaphezulu nelingezansi (i-pharyngeal abscesses, i-tonsillitis, ukuvuvukala kwendlebe ephakathi, i-pneumonia, njll.);
• ukuvuvukala kwephepha lomchamo (cystitis);
• izifo ezithathelwanayo ze-gynecological (isb., i-candida vaginitis);
• ukuvuvukala kwesikhumba nezicubu ezithambile ezidonswa amagciwane ahlukahlukene, kufaka phakathi lezo ezilethwa ukulunywa;
• izilonda ezithathelwanayo zezicubu ezithinta amathambo nezitho;
• izifo ze-odontogenic.

Contraindication

Ukuthatha lo muthi kuphambaniswe ku:

• hypersensitivity to vitu, zombili izakhi ezisebenzayo zomuthi, futhi ezingamalungu eqembu lama-beta-lactam ama-antibiotic;
• ukuba khona emlandweni wokuhlukumezeka emsebenzini wesibindi, ukucasulwa wukudla kwezakhi;
• i-mononucleosis;
• i-lymphocytic leukemia.
  

  I-Amoxiclav iboniswa ama-abscesses we-pharyngeal.

  

  Umuthi usetshenziselwa ukwelapha inyumoniya.

  

  I-Amoxiclav isetshenziselwa ukuvuvukala kwendlebe ephakathi.

  

  I-cystitis iyisibonakaliso sokusetshenziswa kwe-Amoxiclav.

  

  I-Amoxiclav iphatha kahle ukuvuvukala kwesikhumba nezicubu ezithambile.

  

  Umuthi usetshenziselwa ukwelapha i-vaginitis yangempela.

  

  I-Amoxiclav iqeda izimpawu ze-angina.

Ngezifo zesibindi noma izinso, kanye ne-pseudomembrane colitis, umuthi usetshenziswa ngokuqapha.

Ungayithatha kanjani i-Amoxiclav 125?

Ukuzalela kanjani?

Ebhodleleni eliqukethe i-powder, engeza u-40 ml wamanzi. Ngemuva kwalokho kufanele kunyakaziswe ngamandla, kufinyelele ekuphelisweni okuphelele kwe-powder. Ngemuva kwalokho udinga ukufaka cishe i-45 ml bese unikine ngokuphelele futhi. Uketshezi kufanele lufinyelele emaka ngaphandle kwebhodlela.

Umthamo wezingane

Inani elinconyiwe lokumiswa linqunywa yiminyaka yengane kanye nobunzima besifo, ngakho-ke udokotela kuphela ongakunquma kahle umthamo odingekayo. Umenzi kwimiyalo esetshenziswayo ukhombisa amabanga alandelayo:

• ngaphansi kwezinyanga ezintathu - I-15 mg ye-amoxicillin nge-1 kg yesisindo sengane njalo emahoreni ayi-12;
• Izinyanga ezi-3 - Iminyaka eyi-12 - ukusuka ku-7 kuye ku-13 mg / kg njalo emahoreni ayi-8.

Izingane ezingaphezulu kweminyaka engu-12 ubudala azinqunyelwe ukumiswa okwesikhashana. Baboniswa bephuza amaphilisi noma imijovo.

Kwabadala

Abantu abadala ababekelwe ukumiswa kwe-Amoxiclav 125. Kunconywa ukuthatha lo muthi ngesimo samaphilisi noma imijovo. Umthamo omncane ithebhulethi eyi-1 equkethe ama-250 mg we-amooticillin njalo emahoreni ayi-8.

Nge-pseudomembrane colitis, isidakamizwa asinqunyelwe.

I-Amoxiclav ayisetshenziselwa i-mononucleosis.

Izingane ezivela ezinyangeni ezintathu. Kuze kube yiminyaka eyi-12, ukumiswa kunqunywa kumthamo we-7 kuya ku-13 mg / kg njalo emahoreni ayi-8.

Iziguli ezinesifo sikashukela zinconywa inkambo ende yokwelapha ne-Amoxiclav.

Ukuthatha umuthi wesifo sikashukela

Izinto ezisebenzayo ze-Amoxiclav aziguquli amazinga kashukela egazini futhi zingaphelelwa amandla maqondana nokuphazamiseka kwe-metabolic. Kodwa-ke, iziguli ezinesifo sikashukela zinconywa inkambo ende yokwelapha. Isikhathi saso sinqunywa ngudokotela.

Zingaki izinsuku okufanele uthathe?

Isikhathi sokwelashwa nalesi sidakamizwa esichazwe umenzi yizinsuku ezingama-5-16. Uma kunesidingo, ungaqhubeka nokuthatha isikhathi esingaphezu kwamaviki ama-2, kepha awukwazi ukukwenza lokhu ngaphandle kokubonisana nochwepheshe onguchwepheshe.

Imiphumela emibi

Konke ukusabela okungekuhle komzimba okuqashelwayo lapho kuthathwa le antibiotic kumnene futhi kunomlingisi ohamba kancane.

Amapheshana wesisu

Uma uthatha i-Amoxiclav, ungahle uhlangane:

• ukwehla kwesifiso sokudla;
• isicanucanu nokuhlanza
• ukuphazamiseka kwesitulo;
• ukuphazamiseka kwesibindi, umsebenzi owengeziwe we-enzyme;
• Ubuhlungu esifundeni se-epigastric.

Izitho zeHematopoietic

Izitho zeHematopoietic zingaphendula ngokuthi:

• i-leukopenia yemvelo eguqukayo;
• i-thrombocytopenia;
• i-anemia
• i-eosinophilia.

Ukuthatha i-Amoxiclav kungadala i-thrombocytopenia.

Lapho uthatha i-Amoxiclav, ubuhlungu esifundeni se-epigastric bungabonakala.

Lapho usebenzisa umuthi, ungahlangabezana nokubonakaliswa okungalungile okunjengokwehla kwesifiso sokudla.

Ngokuphikisana nesizinda sokuphuza umuthi, ukuhlaselwa inhlokomo kanye nokuhlanza kungenzeka.

Ukuthatha i-Amkosiklav kungadala ukuphazamiseka kwesisu.

Ukusetshenziswa kwomuthi kudala ukungasebenzi kahle esibindini.

Isistimu yezinzwa ephakathi

Ukuthatha lo muthi olwa namagciwane kungabangela ukukhula kwe:

• ukuphazamiseka kokulala;
• isimo sokukhathazeka;
• ukubanjwa
• isiyezi nekhanda.

Kusuka ohlelweni lomchamo

Imiphumela emibi ingafaka i-phenomena efana ne-crystalluria ne-interstitial nephritis.

Allergies

Ukungezwani komzimba nomuthi kuvela ngendlela ethi:

• i-urticaria;
• i-erythema noma i-erythematous rash;
• i-vasculitis.

Ngaphezu kwalokho, ukuthuthukiswa kwe-angioedema kanye ne-anaphylactic shock kungenzeka.

Imiyalo ekhethekile

Ukuhambisana notshwala

Ukusetshenziswa okuhlanganisiwe kwe-Amoxiclav notshwala kuyaphikiswa, ngoba lokhu kunciphisa ukusebenza kwezidakamizwa futhi kukhuphula umthwalo esibindini, okungadala ukudakwa kakhulu.

Ngesikhathi sokulashwa nomuthi, kwenzeka ukuqwasha.

Ukungezwani komzimba nomuthi kuvela ngendlela ye-urticaria.

Ukuphuza umuthi kungadala ukwethuka kwe-anaphylactic.

Ngemuva kokuphuza umuthi, ikhanda nekhanda nesiyezi kuvame ukuvela.

Ngemuva kokuthatha umuthi, ezinye iziguli ziba nesimo sokukhathazeka.

Ukuthatha umuthi kungahambisana nokuquleka.

Ukusetshenziswa okuhlangene kwe-Amoxiclav notshwala kuyabanjwa, ngoba lokhu kunciphisa ukusebenza kahle kwezidakamizwa.

Umthelela ekhonweni lokulawula izindlela

Akukho bufakazi bomphumela omubi wemithamo yokwelapha ye-Amoxiclav ekhonweni lokulawula izindlela. Okuhlukile ukukhula komphumela onjengokuthi isiyezi. Uma sekwenzeka, ukushayela nokusebenza ngamasu ayinkimbinkimbi kufanele kulahlwe.

Ngesikhathi sokukhulelwa nokuqunjelwa

Izakhi zomuthi azibambezeki ngumgoqo we-placental. Ngaphezu kwalokho, zidonswa ngobisi. Yize ucwaningo lungakhombisanga ukuthi lunomphumela we-teratogenic, lapho lungena ku-fetus noma kwi-orgasm yezinsana, kungavela izimo ezingezinhle eziningana. Ngakho-ke, ukuqokwa kwaleli gciwane ngesikhathi sokukhulelwa noma sokubeletha kuvunyelwe, kodwa kuphela uma kunesidingo.

Ngokungasebenzi kahle kwesibindi

Ukuphathwa komuthi ezigulini ezingasebenzi kahle isibindi kufanele kwenziwe ngokuqapha.

Uma kwenzeka ukungasebenzi kahle kwezinso

Ngokuthola kwehlulekile kwe-renal, ukwehliswa komthamo noma ukwanda kwezikhathi zesikhathi phakathi kwemithamo yomuthi kuyadingeka.

Ukuqokwa kwe-Amoxiclav ngesikhathi sokukhulelwa noma i-lactation kuyamukeleka, inqobo nje uma kudingeka ngokuphuthumayo.

Uma imiphumela emibi iba khona ngemuva kokudla umuthi, kufanele wenqabe ukushayela imoto.

Ekwehlulekeni kwezinso, ukunciphisa imithamo kwe-Amoxiclav kuyadingeka.

Uma kwenzeka okweqa ngokweqile kwe-Amoxiclav, ukuqhuma kwesisu kufanele kwenziwe.

I-Rifampicin yenza buthaka imiphumela ye-antibacterial ye-Amoxiclav.

Uma isetshenziswa ndawonye, ​​i-Amoxiclav inyusa ubuthi be-methotrexate.

I-Amoxiclav akufanele isetshenziswe kanyekanye nge-disulfiram.

Ukweqisa

Isibonakaliso esiyinhloko se-overdose ukufutheka okucashile. Ngaphezu kwalokho, ukuthuthukiswa kokuvuka, ukukhathazeka, nokuqwasha kungenzeka. Lesi simo asisiyongo empilweni. Ukwelashwa okubonakalayo kukhonjisiwe. Mhlawumbe i-gastric lavage noma i-hemodialysis.

Ukuxhumana nezinye izidakamizwa

Lapho unquma ngokwelashwa kwe-Amoxiclav, lezi zinto ezilandelayo zokuxhumana kufanele zibhekwe:

• imithi evimba ukukhululeka kwe-tubular, kanye ne-Probenecid, inegalelo ekuqongeleleni kwe-amoxicillin;
• I-Rifampicin, i-sulfonamides kanye nama-bacteriostatic antibiotic enza buthaka umphumela wokulwa nomuthi;
• akwamukeleki ukusebenzisa ngasikhathi sinye nge-disulfiram.

Ngaphezu kwalokho, i-Amoxiclav inyusa ubuthi be-methotrexate.

Lapho kuhlanganiswa nama-anticoagulants, kufanele kuqashelwe ngoba kungenzeka ukwanda kwesikhathi se-prothrombin.

Analogs of Amoxiclav 125

Izindatshana zesidakamizwa yimithi equkethe izinto ezifanayo ezisebenzayo. Lokhu kufaka phakathi izidakamizwa ezifana:

• I-Clamosar;
• I-Ecoclave;
• Augmentin;
• I-Modoclav
• Arlet
• I-Rapiclav.

Izimo zeholide Amoxiclav 125 kusuka ekhemisi

Ngingakwazi ukuthenga ngaphandle kadokotela?

Umuthi kufanele uthengiswe kuphela ngemuva kokwethulwa komyalelo.

Intengo

Intengo ejwayelekile yebhodlela le-Amoxiclav powder yokumiswa ama-ruble ayi-110.

Izimo zokugcina zomuthi

I-vial ye-powder kufanele igcinwe endaweni eyomile endaweni yokushisa yegumbi.

Ukumiswa okulungiselelwe kufanele kube emazingeni okushisa angaphansi kuka-8 ° C.

Isikhathi sokuphelelwa yisikhathi

I-Powder ilungele iminyaka engu-2 kusukela ngosuku lokwenziwa, ukumiswa - izinsuku eziyi-7 kusukela ngosuku lokulungiswa.

Ukubuyekezwa kwe-Amoxiclav 125

Odokotela

USvetlana, udokotela wezingane, oneminyaka engama-30, uMurmansk: "Ngicabanga ukuthi i-Amoxiclav ingumuthi onokwethenjelwa. Uma kunesidingo sokwelashwa ngamayeza okubulala intsholongwane, ngincoma kuqala. Inzuzo enkulu yalesi sidakamizwa ukuthi ivunyelwe ezinganeni kusuka ezinyangeni ezi-3 futhi isetshenziswe ngomama asebekhulile."

U-Oleg, udokotela wezingane, oneminyaka engama-42, uKazan: "Umuthi ubekezelelwa kahle futhi ukhonjiswe ngenani elikhulu lokutheleleka. Uyisibonelo sokuhlanganiswa okuhle kwekhwalithi yaseYurophu nentengo engabizi."

Uma kunesidingo, i-Amoxiclav ingabekwa esikhundleni nge-Arlet.

I-Ecoclave ibhekiselwa kwizifaniso zesimo somuthi, esifana nento esetshenziswayo.

Ungabuyisela umuthi umuthi onjengeClamosar.

U-Augmentin unomphumela ofanayo emzimbeni.

Esikhundleni somuthi kungaba yiRapiclav.

Iziguli

U-Olga, oneminyaka engama-25, uPenza: "Udokotela ubeke lo muthi ngemuva kokwelashwa okungaphumelelanga ngesifo seSumed. I-Amoxiclav isize indodana yami enezinyanga eziyisithupha. Akuzange kube nemiphumela emibi. Kuza ne-dispenser elula nebhodlela lomuthi."

U-Irina, oneminyaka engama-27, uRyazan: "Ngenkathi ingane yami iba nesinitis, udokotela wancoma ukwelashwa nge-Amoxiclav 125. Ngikwazi ukubona ukusebenza kahle nokubekezelela okuhle kwesidakamizwa. Ukuvikela i-microflora, bathatha i-probiotic engaphezulu, ngakho-ke azange kube nezinkinga zokugaya ukudla."