I-insulin ebambela amafushane yenzelwe ukusetshenziswa ezigulini ezinesifo sikashukela i-mellitus. Ngemuva komjovo, inqubo yokuthathwa koshukela yizicubu iyathuthuka. Umuthi uvimbela ukwakheka koshukela esibindini.
Igama Lezwe elingafanele
Insulin.
I-Insuvit N yenzelwe ukusetshenziswa ezigulini ezinesifo sikashukela mellitus.
I-ATX
A10AB01.
Khipha amafomu nokwakheka
Umuthi uyatholakala njengomjovo. Ukwakheka kuqukethe i-100 MO ye-insulin yabantu kanye nabatholi:
- glycerin;
- metacresol;
- i-zinc oxide;
- amanzi wokujova;
- i-hydrochloric acid noma i-sodium hydroxide solution.
Kukhona isengezo sokudla - i-Insuvit emaphaketheni. Umkhiqizo, owenzelwe ukuthuthukisa amandla we-metabolism, uqukethe okukhishwe kwamagxolo esihlahla sesinamoni nezithelo ze-momordiki. Ukuqanjwa futhi kuqukethe i-7 mg ye-Vitamin PP, 2 mg ye-zinc, i-0.5 mg ye-benfotiamine, i-15 μg ye-biotin, i-6 μg ye-chromium, i-5 μg ye-selenium (ngendlela ye-sodium selenite), i-1,2 μg ye-Vitamin B12.
Isenzo se-Pharmacological
Ithuluzi libamba iqhaza ezinqubweni ze-metabolic. I-insulin inamandla okubopha kumaseli omzimba nemisipha. Ukukhiqizwa kwe-glucose esibindini kuyabambezeleka futhi ukumuncwa kwaleli thoni ngama-tishu kwenziwa ngcono. Umenzeli uqala ukusebenza ngesiqingatha sehora. Umphumela uhlala amahora angama-7 kuye kwayi-8. Umphumela omkhulu we-insulin uvela ngemuva kwamahora angama-2-3.
I-Insuvit capsule yenzelwe ukuthuthukisa amandla we-metabolism, iqukethe okukhishwe kwekhonkrithi lekhonkwane nezithelo ze-momordiki.
Isengezo sokudla i-Insuvit sijwayelekile amazinga e-glucose. I-Chromium ibandakanyeka kumthetho wokuqalwa kwamafutha kanye ne-carbohydrate metabolism. Ingasetshenziswa ekwelashweni okuyinkimbinkimbi kwesifo sikashukela i-mellitus, hypercholesterolemia.
I-Pharmacokinetics
Imininingwane ye-Pharmacokinetic ingahluka ezigulini ezihlukene ngokuya ngomthamo, indawo yomjovo, uhlobo lwesifo sikashukela. Amahora angama-2-3 ngemuva kokuphathwa kobuhlakani, ukuhlushwa kwe-plasma kufinyelela phezulu. Izinto zomuthi azihlanganisi namaprotheni e-plasma futhi awenziwa umzimba. Kusulwe ngamaprotheni e-insulin noma ama-enzyme. Uhafu ukhishwe kumahora amabili kuya kwayi-5.
Izinkomba zokusetshenziswa
Umuthi ubekelwe ukwelashwa kwesifo sikashukela ezinganeni nakubantu abadala.
Contraindication
Kwenqatshelwe ukuqala ukwelashwa ngezinga eliphansi le-glucose egazini (ngaphansi kuka-3.5 mmol / l) nokuzwela okuzwakalayo ezingxenyeni zalo muthi.
Ungayithatha kanjani i-Insuvit N
Ithuluzi lingasetshenziswa ngokubambisana ne-insulin esebenza isikhathi eside.
Isidingo se-insulin esigulini ngasinye sihlukile futhi singasukela ku-0.3 kuya ku-1.0 IU / kg ngosuku. Ukungezelela umthamo kungadingeka ukukhuluphala, ukudla okhethekile noma ngesikhathi sokuthomba. Ukwehliswa komthamo kungadingeka uma kukhiqizwa ngokweqile i-insulin emzimbeni.
Umthamo kufanele uguqulwe ngomkhuhlane, izifo, izifo zezinso, isibindi, indlala ye-adrenal, indlala yegilo, indlala ye-adrenal.
Ngesikhathi sokujova, imithetho elandelayo kumele ibonwe:
- Moisten uvolo wekotini ngotshwala futhi ukhubaza ulwelwesi lwerabha.
- Kuyi-syringe pen, dweba umoya omncane bese uyifaka ebhodleleni elinomuthi.
- Nyakazisa ibhodlela bese uthola isilinganiso esifanele somuthi. Ngaphambi kokwethula ngaphansi kwesikhumba, qiniseka ukuthi awukho umoya kwisirinji.
- Ngeminwe emibili, udinga ukwenza isibaya esikhunjeni bese ufaka isirinji engcolisiwe.
- Kubalulekile ukulinda imizuzwana eyi-6 bese ususa isirinji.
- Lapho kukhona igazi, kufakwa uboya bekotini.
I-Alcohol ibhubhisa i-insulin, ngakho-ke awudingi ukuyisebenzisa ukwelapha isiza somjovo. Indawo yomjovo akufanele ihlikiwe ngemuva kwenqubo.
Umuthi uphathwa ngokungaziphathi noma ngemithambo yegazi. Ungangena ngokunqenqema ethangeni, amabhuzu, isisu, izicubu zomsipha wehlombe.
Ngokufakwa kwesidakamizwa esiswini, umphumela utholakala ngokushesha. Kungcono ukwenza imijovo ezindaweni ezahlukahlukene ukuvikela ukubonakala kokuwohloka kwamafutha. Udokotela kuphela ongenza imijovo ye-intravenous.
Ngaphambi noma ngemuva kokudla
Umjovo wenziwa isigamu sehora ngaphambi kokudla.
Ukuthatha umuthi wesifo sikashukela
Umuthi wenzelwa ukwelashwa kweziguli ezinesifo sikashukela i-mellitus. Thatha njengokuyalelwa udokotela.
Imiphumela emibi ye-Insuvit N
I-Insuvit ingadala imiphumela emibi elandelayo:
- ukwehla kokuxineka kwegazi glucose;
- ukungalingani okubonakalayo okuhlukahlukene;
- ukwanda kwesikhashana kwe-retinopathy yesifo sikashukela;
- anaphylaxis;
- izilonda ezibuhlungu zezicubu zemizwa nezicubu zomzimba;
- ukonakala kwamafutha.
Izimpawu endaweni yokujova, ezinjengezinhlungu, i-urticaria kanye nokuvuvukala, ngokushesha zinyamalale.
Umthelela ekhonweni lokulawula izindlela
Ngenxa yemiphumela emibi ehambisana nombono ongasebenzi kanye nokunaka ukunakwa, akunconywa ukushayela izimoto noma izindlela ezinama-hypoglycemia.
Imiyalo ekhethekile
Uma ukwelashwa kuqedwa kungazelelwe noma kunikezwe umthamo onganele, i-hyperglycemia kungenzeka. Ngokubonakala kokuhlanza, isicanucanu, indlala, ukoma nokuchama kaningi, kuyadingeka ukulungisa umthamo. Uma ufaka umthamo ophakeme, amazinga kashukela angakwazi ukwehla kakhulu emazingeni abucayi.
Umuthi awulungele ukuphathwa okuhlala isikhathi eside, okunesilinganiselo, nokulawulwa.
Ungasebenzisi isixazululo esivele senziwe iqhwa noma sinokungaguquguquki kwamafu.
Sebenzisa ebudaleni
Kusetshenziswa ukuguga. Umthamo wansuku zonke unikezwa isiguli ngasinye ngamunye, kucatshangelwa iminyaka yobudala, izifo ezihambisanayo, isigaba sesifo sikashukela.
Isabelo sezingane
Lesi sidakamizwa singachazwa emikhakheni eyahlukene yezingane. Ezinganeni, inani eliphezulu le-insulin egazini lingahluka. Umthamo wesidakamizwa kufanele ukhethwe udokotela ngokwahlukana, kucatshangelwa isigaba sesifo, isisindo somzimba kanye nobudala bengane.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
I-insulin ayiwelanga ku-placenta, lesi sidakamizwa singasetshenziswa ngesikhathi sokukhulelwa. Ngesikhathi sokuncelisa, ukulungiswa komthamo wansuku zonke kungadingeka.
Isicelo sokusebenza kokulimala kwezinso
Ngezifo zezinso ezihambisanayo, umthamo we-insulin ulungiswa udokotela.
Sebenzisa umsebenzi wesibindi okhubazekile
Ngezifo zesibindi ezihambisanayo, umthamo wansuku zonke we-insulin ulungiswa udokotela.
Ukweqisa kwe-Insuvit N
Uma umthamo wedluliwe, ukugcwala kwe-glucose kungahle kwehle kumanani abucayi. Nge-hypoglycemia emnene, kuyadingeka ukudla umkhiqizo oqukethe ushukela. Ezimweni ezinzima kakhulu, uma ukulahleka kwengqondo kwenzeke, i-glucagon iyabhalwa.
Uma ngemuva kwemizuzu engu-10-15 isiguli singabuyanga ukwazi, kuyadingeka ukwethula ushukela egazini. Ukuqinisa isimo, isiguli sinikezwa noma iyiphi i-carbohydrate.
Ukuxhumana nezinye izidakamizwa
Kuphikisiwe ukuxutshwa nama-thiols nama-sulfite, okungenzeka ukuthi kubekhona ekuhlanganisweni kwezixazululo. Sebenzisa kuphela izidakamizwa ezihambisanayo ze-insulin.
Kukhona izidakamizwa ezinciphisa noma ezikhulisa isidingo somzimba se-insulin:
- Ukuvimbela inzalo ngomlomo, i-octreotide, i-lanreotide, i-thiazides, i-glucocorticoids, ama-hormone e-thyroid, ama-sympathomimetics, ama-hormone okukhula kanye ne-danazole akhulisa isidingo se-insulin.
- Ama-ejenti we-Oral hypoglycemic, ama-monoamine oxidase inhibitors, i-octreotide, i-lanreotide, ama-b-blockers angakhethi, ama-angiotensin aguqula ama-enhibme inhibitors, ama-salicylates, ama-anabolic steroid nama-sulfonamides anciphisa ukufunwa kwe-insulin.
Ama-blocker e-Adrenergic angafihla izimpawu ze-hypoglycemia futhi avimbele ukululama ngemuva kwawo. Lapho kuhlangene ne-thiazolidinediones, ukwehluleka kwenhliziyo kungenzeka.
Ama-Analog
Izidakamizwa ezifanayo:
- I-Actrapid HM;
- I-Vosulin-R;
- IGensulin P;
- I-Insugen-R;
- Ifa le-Insulin;
- I-Insuman Rapid;
- I-Rinsulin-R;
- I-Farmasulin H;
- I-Humodar R;
- Humulin Njalo.
Ngaphambi kokusebenzisa, udokotela kufanele ahlole isiguli ukunquma umthamo ofanele.
Ukuhambisana notshwala
Kunconywa ukuyeka utshwala ngesikhathi sokwelashwa. Ukuphuza iziphuzo eziqukethe i-ethyl kungadala ukukhula kwe-hypoglycemia. Ezimweni ezingafani, ukwamukelwa kuholele enkingeni.
Imibandela yekhefu lekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela
Emakhemisi, isidakamizwa sikhishwa emgqonyeni kadokotela.
Intengo ye-Insuvit N
Izindleko zomuthi zivela kuma-ruble angama-560.
Izimo zokugcina zomuthi
Gcina umuthi endaweni yokushisa +2 kuya ku- + 8 ° C esiqandisini. Kuyenqatshelwa ukuthi iqhwa.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelf iyiminyaka emi-2.
Ibhodlela elivulekile ligcinwa izinsuku ezingama-42. Ukushisa akufanele kudlule + 25 ° C. Ibhodlela elivulekile akufanele ligqoke ilanga.
Umkhiqizi
I-PJSC Farmak, Biocon limited, India.
Ukubuyekezwa mayelana ne-Insuvit N
UValeria, oneminyaka engama-36
Umuthi wawumiselwe uhlobo 1 sikashukela. Umthamo wakhethwa ngokucophelela ukuvikela ukuguquguquka okungazelelwe kushukela wegazi. Ngesikhathi sokulashwa, waphawula ukukhathala kancane nesiyezi, kodwa izimpawu zasheshe zaphela. Ngijabule ngomphumela.
Anatoly, iminyaka engama-43
Ngisebenzisa umuthi ngokuhlanganiswa ne-insulin esebenza isikhathi eside. Umphumela omuhle, intengo enengqondo. Imijovo yenziwa ethangeni, kwathi indawo yomjovo yavutha kancane. Kwakunezinhlungu nemizwa yokuhwaya. Isimo sibuyele kwesijwayelekile ngemuva kwesonto. Ngihlela ukuqhubeka nokwelashwa.
U-Evgeny Alexandrovich, udokotela wezokwelapha
I-Insuvit N ibekezelelwa kahle yiziguli ezinhlobonhlobo yesifo sikashukela. Ngaphambi kokunquma umthamo, kufundwa izinto eziningi, kufaka phakathi isimo sesiguli, isigaba sokuxinana, kanye nobudala. I-Insuvit esinye isidakamizwa esisetshenziswa ekwelapheni lesi sifo. Umuthi wokudla uqukethe amaminerali, amavithamini kanye nezithako ezomile zesitshalo. Kuthuthukisa umsebenzi wezindlala ze-endocrine, ibuyise i-carbohydrate namandla we-metabolism.
