Izidakamizwa ze-antibiotic zithandwa kakhulu ngabodokotela neziguli. Kepha lolu chungechunge lwezidakamizwa lufuna ukunakwa okukhethekile lapho kunqunywa. Ngaphezu kwalokho, imithi elwa namagciwane ayinakunqunywa ngokwayo, ngoba indlela abahlangabezana ngayo kwesinye isikhathi ihlukile. Kukhona izidakamizwa ezinesithako esifanayo esisebenzayo, kepha ngezindawo ezingezekile. Izimali ezinjalo zifaka, ngokwesibonelo, i-Flemoxin ne-Amoxicillin.
Isici sikaFlemoxin
UFlemoxin, othengiswa emakhemisi ngaphansi kwegama lokuhweba uFlemoxin Solutab, umuthi olwa namagciwane atholakala kwifomu lethebhulethi ku-125, 250, 500 no-1000 mg, aqukethe emgodleni wayo ingxenye yengxenye yochungechunge lwe-penicillin uchungechunge i-amohydillin kanye nezinye izithako ezingeziwe:
- cellulose ehlakazekile ne-MCC;
- i-crospovidone;
- i-magnesium stearate;
- i-vanillin ne-saccharin;
- izihlungi zezithelo.
UFlemoxin Solutab umuthi olwa namagciwane atholakala kwifomu lethebhulethi ku-125, 250, 500 kanye no-1000 mg.
UFlemoxin usebenza kahle ngokubhujiswa kwamagciwane angenalo i-gram-positive ne-gram-negative, kepha unomphumela omubi ku-staphylococcus ne-protein. I-antibiotic ayisebenzi nge-meningitis, ngoba inqubo yokungena emzimbeni we-cerebrospinal fluid yinde kakhulu.
Uma ususengogus, umuthi udonswa ngokushesha bese ungena egazini. Ukwenza i-metabolites kube ngama-metabolites asebenzayo, i-antibiotic ibhubhisa igobolondo lamagciwane alimazayo futhi ichithe izifo. Okuqukethwe kwayo okuphezulu kubonwa ngemuva kwehora, ukuphuma komuthi kuhlinzekelwa izinso.
Indlela yesifundo ngokuya ngohlelo lwakudala iboniswa izikhathi ezingama-2-3 ngosuku, imizuzu engama-20 kuya kwengama-30 ngaphambi kokudla (noma inani elifanayo emva kwalokho), izinsuku eziyi-5 (kwesinye isikhathi eside, kepha khumbula ukuthi ukusetshenziswa kwesikhathi eside kwama-antibhidakamizwa ayimilutha futhi kuthinta ukusebenza ngempumelelo ukwelashwa).
UFlemoxin uvunyelwe:
- izingane (imithamo emincane);
- ngesikhathi sokukhulelwa;
- ngokukhuphuka (ngokuqapha).
Isici se-Amoxicillin
Ithuluzi elingelokulwa nama-semisynthetic kweqembu le-penicillin, elibhekwa njengeliphephe kunazo zonke izidakamizwa ezikhona ze-antibacterial. Umuthi uthandwa kakhulu phakathi kochwepheshe, kubandakanya nezingane.
I-Amoxicillin ingeyama-penicillin ama-semi-synthetic, athathwe njengephephe kunazo zonke.
Izinhlobo zomuthi:
- amaphilisi we-250, 500 ne-1000 mg;
- granules zokumiswa - 250 mg / 5 ml;
- ama-ampoules ane-15% r-r asetshenziswa kwezokwelapha.
Ukwakheka kwezindlela eziqinile zama-antibiotic kufaka phakathi izithako ezingeziwe:
- i-polysorbate (phakathi kuka-80);
- i-magnesium stearate;
- isitashi;
- i-talcum powder.
Ukutholwa kwesidakamizwa kwenzeka ngokushesha, kepha ukungena mucosa esiswini futhi kungathinti i-acidity nganoma iyiphi indlela. Uma ukudla okungavuthwanga kuhlala esiswini, khona-ke lokhu akukuthinti ukugaya ukudla. Umthamo omkhulu wesidakamizwa ekujuleni kwegazi ugxiliswa ngemuva kwamahora ama-2, kuthi ama-20% asatshalaliswe ndawonye ngamaprotheni e-plasma, okunye ukwakheka ngokulinganayo kungena kuzo zonke izicubu. I-Amoxicillin iboniswa ezimweni eziningi zokuvuvukala ezibangelwa yi-pathogenic ezincane.
Nikeza amaphilisi (ngosuku):
- abantu abadala nezingane kusuka eminyakeni engu-9 ubudala - 500 mg izikhathi ezi-3;
- kwezifo eziseduze - kuze kufike ku-1000 mg izikhathi ezi-3;
- iziguli ezingaphansi kweminyaka engu-8 ubudala - 250 mg izikhathi ezi-3.
Isikhathi sokwelashwa nge-Amoxicillin silingana nezinsuku ezingama-5-7.
Isikhathi sokwelashwa okujwayelekile sezinsuku ezingama-5-7. Kepha ukuqokwa kwemithi elwa namagciwane kungenzeka kuphela kwi-Amoxicillin kungokwama-semisynthetic antibiotic eqenjini le-penicillin, athathwa njengaphephe kakhulu. Izincomo zikadokotela, ngoba kunemiyalo ehlukile yezifo ezahlukahlukene:
- i-otitis ezinganeni - umthamo omncane uboniswa izikhathi ezi-2, izinsuku ezi-5;
- i-leptospirosis (yabantu abadala) - 0.5 g 4-fold, kuze kufike ezinsukwini eziyi-12;
- nge-salmonellosis - 1 g izikhathi ezi-3, izinsuku eziyi-15-30;
- iziguli ezinesifo sezinso - umthamo ophelele we-2 g;
- ukuvimbela i-endocarditis ngesikhathi sokuhlinzwa - 4 g ihora ngaphambi kwenqubo.
Ukuqhathaniswa kweFlemoxin ne-Amoxicillin
I-Amoxicillin ingukuqala kwemithi eminingi yesimanje yokulwa namagciwane. Umuthi lo ubusemakethe isikhathi esingaphezu kweminyaka engama-50, ngalesi sikhathi izinkampani eziningi zemithi zethule umkhiqizo wazo:
- Bayer - Germany;
- I-World Pharmaceutical - e-USA;
- Umkhiqizo waseNatur - ENetherlands;
- USerena Pharma - eNdiya;
- IHemofarm - IYugoslavia;
- Umkhiqizo webhayoloji, i-Biochemist, i-Bryntsalov-A, i-Vertex, i-Pharmasynthesis nabanye - iRussia.
Yena uqobo unamaphutha amaningi, lawo alungiswa ngokuqalwa kweFericxin Solutab ejwayelekile, ebilokhu ikhiqizwa yi-Astellas Pharma Corporation (Netherlands) kusukela ngo-2005.
Ukufana
Isenzo sale mithi elwa namagciwane sisuselwa kumandla engxenye yabo esebenzayo esebenzayo - amoxicillin trihydrate. Yomibili le mishanguzo isuselwa ezingomeni zeqembu le-penicillin, ezithinta izimbali zezimbali ngendlela efanayo - zibhubhisa amagciwane ngokungena kolwelwesi. Izinkomba ezisetshenziselwa ukumbozwa kwezifo zohlobo lwegciwane:
- i-leptospirosis;
- i-endocarditis;
- i-sinusitis
- i-bronchitis;
- pharyngitis;
- i-tonsillitis;
- abezindaba ze-otitis;
- inyumoniya
- ukutheleleka kwezinso nethamo lomchamo;
- ukuvuvukala ku-gynecology;
- ukutheleleka kwesikhumba (i-dermatosis, erysipelas);
- isilonda sesisu.
Contraindication:
- ukubekezelela i-penicillin;
- i-lymphocytic leukemia;
- isifuba somoya
- izihlakala;
- isifo sezinso esinzima.
Imiphumela emibi eyenzeka nge-hypersensitivity ne-overdose:
- i-anemia
- i-candidiasis;
- i-thrombocytopenia;
- i-jade;
- i-stomatitis
- ukungalali kahle kanye nesifiso sokudla;
- ukudideka kokwazi;
- i-leukopenia;
- ukubonakaliswa komzimba (kufaka phakathi i-edema kaQuincke);
- ukukhungatheka kwamathumbu;
- iminyakazo.
Uyini umehluko
Umehluko omkhulu phakathi kwale mithi ngukuthi i-Flemoxin ikhiqizwa ngohlobo lokuncibilikisa kakhulu futhi ngasikhathi sinye amafomu amelana ne-acid. Ingxenye esebenzayo, engena esiswini, ayiphuli ngaphansi kwesenzo se-hydrochloric acid, kepha idlulela emathunjini, lapho imunwa khona ngaphezu kwe-90% yegazi. Lokhu kuvumela umuthi wokulwa namagciwane ukuthi ungene ngokukhululekile ekugxiliseni okujulile kwezifo kwimithamo efanele.
I-Amoxicillin inesakhiwo sokuhluke ngokuphelele, ngakho-ke iqala ukubhidliza ngisho nasesiswini, yingakho ingangenwa ngokuphelele. Kepha isidakamizwa esidala nesihlolwa isikhathi singcono ngokuvuvukala kwe-microflora esiswini. Ukuphathwa ngokubambisana kwezidakamizwa akwenziwa (ngemuva kwakho konke, yinto efanayo), ingxenye ephindwe kabili izodlula okujwayelekile, okuyingozi ngokuphendula okuhlukile. Futhi kuvunyelwe ukufaka imali esikhundleni sokwelashwa.
Ukubuyiselwa okungenakuqhathaniswa nakho kungabikwa ukuthi i-Amoxicillin ibabile.
UFlemoxin uvelele maqondana ne-analogue yakhe ngendlela ekhethekile yokwakheka kwengqangi. Izinzuzo zako:
- imunca ngokushesha emgodini wokugaya ukudla;
- ine-bioavailability enkulu;
- sibonga ulwelwesi olukhethekile, lungene egazini, sidlula emgodini wesisu;
- kunalokho ifinyelela ekuhlushweni okuphezulu kakhulu.
Ukubuyiselwa okungenakuqhathaniswa nakho kungabikwa ukuthi i-Amoxicillin ibabile. UFlemoxin unikezwe iphunga elimnandi nokunambitheka okumnandi.
Okuphephile
UFlemoxin umuthi osethuthuke ngokwengeziwe. Njengesithako esisizayo, iqukethe i-cellulose, enikeza ukungcola okungcono, kanye nenani elincane loketshezi. I-Flemoxin imvunyelwa ukuthi isetshenziswe ngesikhathi sokukhulelwa. Isipiliyoni sesikhathi eside ekunqumeni lesi sidakamizwa sinikeza ilungelo lokucubungula umuthi njenge-antibiotic ephephile evunyelwe ezinganeni ezincane nakwabesifazane abakhulelwe. Kodwa-ke, ukwakheka okusizayo kukaFlemoxin kuqukethe i-saccharin, okusho ukuthi kungcono ukuthi iziguli ezinesifo sikashukela zinikeze ukwakheka okudala.
Yikuphi okushibhile
Intengo emaphakathi ye-Amoxicillin:
- Amaphilisi we-250 mg No. 20 - 26.10 ruble.; 500 mg No. 20 - 56.50 ruble.; I-1000 mg engu-12 - ama-ruble ayi-140;
- granules d / ukumiswa. I-100 ml (250 mg / 5 ml) - ama-ruble angama-76.50.
I-Flemoxin imvunyelwa ukuthi isetshenziswe ngesikhathi sokukhulelwa.
Izindleko zamathebulethi uFlemoxin Solutab No. 20:
- 125 mg - 194.50 rub .;
- 250 mg - ama-ruble angama-238.50;
- 500 mg - ama-ruble angama-312;
- 1000 mg - 415.50 rub.
Uma uqhathanisa amanani, kuyacaca ukuthi kunenzuzo enkulu ukuthenga i-Amoxicillin.
Yikuphi okungcono - Flemoxin noma Amoticillin
Ochwepheshe bakholelwa ukuthi intuthuko yakamuva yezokwelapha okuhloswe ngayo ukwenza ngcono izakhiwo, ukuphepha, ukuthuthukisa ezinye izindlela, yenza i-Flemoxin ibe yisinqumo esingcono kakhulu. Abathuthukisi, besusa ukushiyeka kwe-Amoxicillin, bashiye izimfanelo ezinhle kakhulu. Ukwehluka kwe-bioavailability kwezidakamizwa zohlobo oluthile kukhiqize, futhi imiphumela emibi inciphile. Kodwa ukuthola ukuthi iyiphi indlela esebenza ngempumelelo, udokotela kufanele, ngokususelwe kuzinkomba ezilandelayo:
- isifo samanje;
- ubukhulu besimo;
- iminyaka yesineke;
- izinkomba zokubekezelelwa kwengxenye.
Enganeni
Yize zombili lezi zidakamizwa zingasetshenziswa ezinganeni, uFlemoxin unqunywa kaningi, kusukela:
- amafomu alo ethebhulethi anomthamo ophansi kune-amoxicillin;
- Izibhebhe zezingane ze-125 mg zilungele kakhudlwana ukuncibilika emanzini;
- zingasetshenziswa ngisho nakubantu abasanda kuzalwa;
- zingancibilika ebisini lwebele.
Ukwenza umntwana azimisele ngokuphuza umuthi, kubalulekile ukucubungula ukunambitheka kwawo. Lapha uFlemoxin uwina futhi, ngoba ayinakho ukufutheka okukhona kumathebhulethi amaningi. Osokhemisi be-Astellas Pharma bathatha indawo yokunambitheka okumunyu kwe-Amoxicillin ngama-saccharin nama-flavour agents.
Ukubuyekezwa kodokotela
S.K. I-Sotnikova, udokotela wobuciko, eMoscow
Udinga ukuthenga kuphela umthamo ofanele. Ukwabelana ngaleli gciwane akunconywa. Ungaqaphela ukuthi amaphilisi amaningi asengozini. Lokhu akusho ukuthi umthamo wabantu abadala ungahlukaniswa waba yizingane. Ukuhlukaniswa akwenzelwa ukwenza ivolumu yomuthi izikhathi ezi-2 ibe yincane - igobolondo elingaphandle livikela ithebhulethi ezintweni ezonakalisayo.
G.N. Sazo, udokotela wezingane, iNovgorod
Ngemidiya ye-otitis, noma iyiphi yalezi zimali ingabelwa izingane ngokuphepha. Imiphumela emibi mincane. Ngincoma ukuyithatha kuze kuphele izimpawu eziyinhloko nezinsuku ezimbalwa.
T.M. I-Tsarev, udokotela wamazinyo, Ufa
I-Amoxicillin iyi-antibiotic edume kakhulu emhlabeni, eyakhiwa ngabathengisi bemithi ngeminyaka yama-60s yekhulu lokugcina eBrithani. Futhi uFlemoxin ungudokotela wakhe ophumelele. Kodwa i-allergy ngesimo se-urticaria yahlangatshezwa (nge-overdose).
Ukubuyekezwa Kwesiguli kwe-Flemoxin ne-Amoxicillin
UMaria, oneminyaka engama-33, uTula
Umuthi omuhle kakhulu wokubulala amagciwane yi-Amoxicillin. Bengingazi ukuthi kukhona i-analogue ye-tastier. Amanani aphakeme, kepha enganeni ngizoyikhetha.
UTatyana, oneminyaka engama-45, uKimry
Umthamo kanye nama-regimen ama-antibiotic angawodwana, kuya ngokuthi yikuphi ukwelapha. Uma kungenzeka iziguli ezinesilonda esiswini, khona-ke nezinkinga ngama-gallder bladder antibiotics azinakwenzeka (njengoba kusho udokotela). Ungazindli.
UKatya, oneminyaka engama-53, u-Ukhta
UFlemoxin wanqunyelwa ukuthi elashwe ukukhwehlela okungapheli. Kuhle ukuthi kunuka njengolintshi, kepha njengoba izindlela zicishe zifane, ngincamela i-Amoxicillin engabizi kakhulu futhi efakazelwe kakhulu.
