I-Neurontin 300 iyisidakamizwa esiyingxenye yamakhambi eziyinkimbinkimbi zokwelapha izifo ezihambisana ne-convulsive syndrome. Ine-contraindication nemiphumela emibi, ngakho-ke kufanele isetshenziswe ngaphansi kokuhlolwa udokotela.
Igama Lezwe elingafanele
UGabapentin
I-Neurontin 300 iyisidakamizwa esiyingxenye yamakhambi eziyinkimbinkimbi zokwelapha izifo ezihambisana ne-convulsive syndrome.
I-ATX
N03AX12
Khipha amafomu nokwakheka
Umuthi unesimo sezibhebhe ezihlanganiswa ngefilimu emhlophe ye-enteric., Ezinobunjwa obungama-oval, biconvex. Ngakolunye uhlangothi kukhona ingozi yokuhlukaniswa. Ithebhulethi ngayinye iqukethe:
- i-gabapentin (300 mg);
- i-monohydrate kashukela;
- isitashi samazambane;
- titanium dioxide;
- i-talc;
- i-magnesium stearate;
- cellulose powder.
Iithebhulethi zinikezwa kumaseli e-contour zezingcezu eziyi-10, ezibekwe emabhokisini amakhadibhodi. Ibhokisi lingafaka phakathi ama-2, 5 noma ama-10 ama-blisters nemiyalo.
Iithebhulethi zinikezwa kumaseli e-contour zezingcezu eziyi-10, ezibekwe emabhokisini amakhadibhodi.
Isenzo se-Pharmacological
IGabapentin inezakhiwo ezilandelayo:
- unesakhiwo esifana ne-gamma-aminobutyric acid, kepha indlela esisebenza ngayo ihlukile kunaleyo eminye izidakamizwa ye-antiepileptic esebenza kuma-GABA receptors;
- ibopha izingxenye zeziteshi ezithembela ku-voltage, icindezela ukusebenza kwama-ion e-calcium, enomthelela ekuqubukeni kwezinhlungu ze-neuropathic;
- kunciphisa isilinganiso sokubhujiswa okuncike ku-glutamate kwama-neurons, kwandise ukukhiqizwa kwe-gamma-aminobutyric acid, kuvimbela ukuhlanganiswa kwe-monoamine neurotransmitters;
- ayihlangani nama-receptors amanye ama-anticonvulsants noma ama-neurotransmitters;
- yenza buthaka isenzo se-glutamate receptor agonist;
- kunciphisa ukwenziwa kwe-monoamine neurotransmitters;
- kusheshise imetabolism ye-gamma-aminobutyric acid ezicutshini zobuchopho;
- kuvimbela ukuthuthukiswa kokuxhuga okubangelwa i-electroshock, amakhemikhali nezifo zofuzo.
I-Pharmacokinetics
Ngokuphathwa ngomlomo, kugxilwa kakhulu nge-plasma ye-gabapentin ngemuva kwamahora ama-3. Ukudla akuphazamisi ukumuncwa kwento esebenzayo.
Emzimbeni womuntu, umuthi awuthelwanga umzimba. Ingxenye yedosi ethathiwe ihoxiswa kancane kancane kungakapheli amahora ayi-6. Iningi lomthamo othathwe lishiya umzimba nomchamo ungashintshiwe.
Izinkomba zokusetshenziswa
Umuthi usetshenziselwa:
- ama-neuropathies ezigulini zabantu abadala;
- i-monotherapy yokuthathwa kokunye okuyingxenye kweziguli ezingaphezulu kweminyaka eyi-12;
- ukwelashwa okuhlangene kokuthathwa kokunye okujwayelekile kwabadala nezingane ezingaphezulu kweminyaka emi-3.
Contraindication
I-Neurontin ayisetshenziselwa ukungezwani komzimba ne-gabapentin nezithako ezisizayo zomuthi.
Ngokunakekela
Ukuhlukumeza okuhlobene nokusetshenziswa kwe-anticonvulsant yizifo zesistimu ye-excretory ezingabambezela ukuphuma kwe-renal ye-gabapentin.
Ungayithatha kanjani i-Neurontin 300
Umthamo wesidakamizwa uncike ohlotsheni lwesifo:
- I-Neuropathy. Ukwelapha kuqala ngokungeniswa kwe-900 mg ngosuku. Umthamo wansuku zonke uhlukaniswe ngezinhlelo ezi-3. Ngokuya ngokusebenza komuthi, umthamo ungakhuphukela ku-3 g ngosuku.
- Ukukhishwa okuyingxenye kweziguli ezingaphansi kweminyaka engu-18. Umthamo wansuku zonke onconywayo ngu-600 mg. Uma kungekho mphumela, inyuka yaba ngu-1.8 g.
- Ukuquleka okuyingxenye kubantu abadala. Ama-900-3600 mg we-gabapentin athathwa ngosuku. Ngokubekezelela okujwayelekile kokwelashwa kanye nokuvela kaningi kokuqanjwa kokukhonkotha, umthamo wansuku zonke uyanda ube ngu-4,8 g. Isikhathi esiphakathi kwamatafula lapho uhlukanisa umthamo wansuku zonke izingxenye ezintathu kufanele ungeqi amahora ayi-12.
- Isifo se-Convulsive syndrome ezinganeni ezineminyaka engu-3 kuya kwengu-12 ubudala. Ukwelashwa kuqala ngokufakwa kwe-10-15 mg / kg ngosuku. Umthamo wansuku zonke uhlukaniswe izingxenye ezintathu ezilinganayo. Amaphilisi anikezwa ingane njalo emahoreni ayi-8. Ezinsukwini ezintathu, umthamo wanda kancane kancane waba ngu-25-30 mg / kg. Ngokusetshenziswa isikhathi eside, ukusebenza komuthi kungancipha, okufuna ukwenyuka komthamo ukuya ku-50-100 mg / kg.
Ngoshukela
Ngokuthuthukiswa kokuxhamla kweziguli ezinesifo sikashukela, ukulungiswa kwamthamo akudingekile, noma kunjalo, ukwelashwa kufanele kuqhubeke ngaphansi kokuqondisa udokotela.
Ngokuthuthukiswa kokuxhamla kweziguli ezinesifo sikashukela, ukulungiswa kwamthamo akudingekile, noma kunjalo, ukwelashwa kufanele kuqhubeke ngaphansi kokuqondisa udokotela.
Imiphumela emibi yeNeurotonin 300
Umuthi ungadala imiphumela emibi ehambisana nokulimazeka kwezitho nezinqubo ezahlukahlukene.
Amapheshana wesisu
Ukwehlula kohlelo lokugaya ukudla kuyabonakala:
- ukwanda kwegesi;
- ukwehla kwesifiso sokudla;
- isifo sezinsini;
- ukubhujiswa koqweqwe lwawo;
- ukwanda kwesifiso sokudla;
- ulwelwesi olomile lwethambo lomlomo;
- ubuhlungu esifundeni se-epigastric;
- izikhathi zokuhlanza.
Izitho zeHematopoietic
Umuthi uvimbela ukusebenza kohlelo lwe-hematopoietic, okuholela ekunciphiseni kwenombolo ye-leukocytes kanye nokuthuthukiswa kwezinkinga ze-hemorrhagic.
Isistimu yezinzwa ephakathi
Lapho umuthi uthinta uhlelo lwezinzwa, kukhona:
- ikhanda
- Isiyezi
- ukukhuphuka kwezimoto ngemoto;
- ukunyamalala kwezikhwepha;
- sedation kanye nobuthongo;
- ukwephulwa kwemisebenzi yezinzwa (ukwehla kwezimpawu zezindlebe nokuzwa, ushintsho ekunambithekeni)
- ukunyakaza ngokuzithandela kwe-eyeballs;
- amazwe acindezelayo;
- ukukhubazeka kwenkumbulo;
- ukungazi kahle;
- ukungazinzi ngokomzwelo;
- ukucabanga okungahambi kahle;
- imilenze ethuthumela;
- ukucindezelwa kokuphefumula.
Kusuka ohlelweni lomchamo
Umuthi ukhulisa ubungozi be-cystitis ne-pyelonephritis.
Kusuka ohlelweni lwe-musculoskeletal
Ngokwemuva kokuthatha i-Neurinu, ungahle uthole:
- imisipha nobuhlungu obuhlangene;
- i-pathological fractures;
- Ubuhlungu emgogodleni.
Engxenyeni yesikhumba
Lapho uthatha i-anticonvulsant, kuqubuka imichilo yesikhumba ekhishwa, i-urticaria, ukuqubuka kwezidakamizwa, ukuqubuka kwemvelo.
Allergies
Ukusetshenziswa kweNeurontin kungavusa ukubukeka kokukhwehlela komzimba nekhala eligudlayo, i-edema kaQuincke, i-eosinophilia, ukushaqeka kwe-anaphylactic.
Umthelela ekhonweni lokulawula izindlela
Umuthi ungathinta ukusebenza kohlelo lwezinzwa oluphakathi, unciphise ukugxila kokunakwa kanye nesivinini sokuphendula, ngakho-ke ngesikhathi sokunqaba bayenqaba ukusebenza ngamasu wokulwa anzima.
Imiyalo ekhethekile
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngesikhathi sokukhulelwa, i-Neurontin imiselwe kuphela uma ama-anticonvulsants aphephile engasebenzi. UGabapentin ungena ebisini, ngakho-ke, ngesikhathi sokwelashwa, ingane idluliselwa ekunikezeni ukudla okungelona iqiniso.
Ukunquma i-neurontin ezinganeni ezingama-300
Amacwecwe akufanele anikezwe iziguli ezingaphansi kweminyaka engu-3.
Sebenzisa ebudaleni
Lapho unquma umuthi kubantu asebekhulile nabanenhliziyo, kungenzeka ukuba khona kwama-pathologies adinga ukuguqulwa komthamo kuthathwa.
I-overdose ye-Neurotonin 300
Ubuthi benzeka ngokusetshenziswa kuka-5 g we-gabapentin. Ihambisana nesiyezi, idiplopia, i-lethargy kanye nezitulo ezikhululekile. Ukwenza isimo somuntu sibe sesijwayelekile, kusetshenziswa ukwelashwa okubonakalayo. Ngokulimazeka okukhulu kwezinso, umuthi ukhishwa emzimbeni nge-hemodialysis.
Ukuxhumana nezinye izidakamizwa
IMorphine inciphisa ukumuncwa kwe-gabapentin, inciphisa umsebenzi wayo we-anticonvulsant. Umuthi awuhlangani ne-phenytoin, phenobarbital, valproic acid. Ngokusetshenziswa kanyekanye nezindlela zokuvimbela inzalo zomlomo ezihlanganisiwe, ukusebenza kokugcina kungancipha. Ama-antacid anciphisa ukumuncwa kweNeurinu. I-probenecid ayiguquli imingcele ye-pharmacokinetic ye-gabapentin.
Ukuhambisana notshwala
Ukuphuza utshwala ngesikhathi sokwelashwa kukhulisa amathuba emiphumela emibi evela ohlelweni lwezinzwa.
Ama-Analog
Ukufakwa esikhundleni kwe-Neurontin yile:
- Convalis;
- Katena
- IGabagma
- Tebantin.
Imibandela yekhefu lekhemisi
Akunakwenzeka ukuthenga umuthi olwa nama-anticonvulsant ngaphandle kadokotela.
Intengo yeNeurontin 300
Izindleko ezijwayelekile zamathebulethi ayi-100 ama-ruble ayi-1,500.
Izimo zokugcina zomuthi
Amacwecwe agcinwa emaphaketheni awo okuqala, avikela ekuvezelweni ukukhanya nokukhanya.
Isikhathi sokuphelelwa yisikhathi
I-Neurontin ilungele ukusetshenziswa kungakapheli izinyanga ezingama-24 kusukela ngosuku lokukhishwa.
I-Neurontin ilungele ukusetshenziswa kungakapheli izinyanga ezingama-24 kusukela ngosuku lokukhishwa.
Umkhiqizi
Lesi sidakamizwa senziwa yinkampani yezokwelapha iPfizer, e-USA.
Ukubuyekezwa kweNeurinu 300
UMaria, oneminyaka engama-58, uRyazan: "Isazi sezinzwa sinqume umama nge-neuropathy ehambisana nobuhlungu ezingalweni nasemilenzeni. Esikhathini eside bebengakwazi ukuqonda imbangela yobuhlungu, kuphela ukuhlolwa okuphelele okusiza ukuthola ukuvuvukala kwezinzwa zempilo." Umama wathatha amaphilisi ekuseni, ntambama nakusihlwa. Ubuhlungu buyehla kakhulu. Umama waqala ukuhamba kakhulu, enza imisebenzi yasendlini. Ngemuva kwesifundo sezinyanga ezintathu, izinhlungu zaphela ngokuphelele. "
USvetlana, oneminyaka engu-38 ubudala, eSt. kulo muthi, indodakazi iphila impilo ejwayelekile. "
