Amatafula noma imijovo i-Actovegin isidakamizwa esibalulekile ekwelapheni ama-pathologies ahlukahlukene wesistimu yengozi noma yesistimu yezinzwa ephakathi, enezinkinga ze-metabolic, ukuphazamiseka kwe-oksijini okhubazekile kwamaseli womzimba, njll.
Umuthi osebenzayo uyefana nalapha - i-actovegin, i.e. kunyiswe i-hemoderivative ethathwe egazini lethole. Umehluko ku-bioavailability yefomu elithile noma elinye.
Izici Actovegin
Umuthi lo ubusetjenziswa emikhakheni yezokwelapha kusukela maphakathi nawo-1970. Kuyinto hemoderivative okwehlisiwe. Ikhiqizwa kusetshenziswa ubuchwepheshe besimanje, i-ultrafiltration, futhi ihlanza ukuhlanza ngezigaba eziningi.
Ithebhulethi noma imijovo i-Actovegin isidakamizwa ekwelapheni ama-pathologies ahlukahlukene wesistimu yengozi noma yesistimu yezinzwa.
Ikhompiyutha ebangelwa yile iqukethe ama-amino acid, ama-enzyme, ama-oligopeptides, ama-macro- kanye nama-microelements ahlukahlukene (phosphorus, sodium, calcium, magnesium, ithusi, abicah) nezinye izinto ezisebenzayo ezithinta uhlelo lwezinzwa. Ngaphezu kwalokho, ama-macro- kanye nama-microelements ashiwo ku-Actovegin akhona ngesimo sikasawoti, esinomthelela ekufakweni kwawo okungcono.
Ithuluzi linconyelwa ama-pathologies afana nezilonda ezahlukahlukene zohlelo lwezinzwa, ukuphazamiseka kwemizwa kwengqondo nezifo ezihambisana nokungasebenzi kahle ezinqubweni ze-redox nezinqubo ze-metabolic.
Amathebulethi ayindlela evamile kakhulu yokukhishwa kwe-Actovegin.
I-Actovegin inomphumela oyinkimbinkimbi ezingeni lamaselula. Kwandisa ukusetshenziswa kwe-glucose futhi ngasikhathi sinye i-metabolism isebenze, kusebenze amandla we-metabolism, kuthuthukisa ukusetshenziswa kwe-oxygen. Yize ukusetshenziswa kwe-glucose kukhuphuka ngesikhathi sokusetshenziswa kwayo, lokhu akubangeli ukwanda koshukela wegazi, ngoba ukwakheka kwesithako esisebenzayo kufaka i-inositol phosphate oligosaccharides, enomphumela ofana ne-insulin.
Umuthi awuthinti ama-insulin receptors ngokwawo, futhi isifo sikashukela asikona ukweqa ukusetshenziswa kwaso.
Amaphilisi
Kunezindlela ezahlukahlukene zokukhishwa kwe-Actovegin. Lokhu akuyona amaphilisi noma ama-ampoules kuphela, kepha futhi namafutha, ijeli no-ayisikhilimu. Kodwa-ke, amaphilisi yiyona ndlela evame kakhulu. Aqukethe i-hemoderivative esele ikhishwe (i-200 mg kwithebhulethi eyi-1), i-magnesium stearate, i-cellulose nezinto ezakha igobolondo (lokhu yi-glycolic Mountain wax, i-acacia gum, i-sucrose, i-titanium dioxide, njll.).
Imijovo
I-Actovegin akuyona nje ama-ampoules anokuqukethwe kwendawo yonke. Ngokwehlukana, kukhishwa isixazululo somjovo, oqukethe ukugxila kwe-actovegin kumthamo we-20 mg ku-1 ml, ngokwahlukana - isisombululo sokufakwa kwe-10% (lokhu kwamuva kusetshenziswa lapho odokotela beyalela abelahla). Kulokhu, abamukeli ekwakhekeni komuthi kulezi zimo zombili bafaka okufanayo - amanzi ne-sodium chloride.
Isixazululo somjovo siqukethe ukugxila kwe-Actovegin kumthamo we-20 mg ku-1 ml.
Ukuqhathanisa Izidakamizwa
Kulokhu, sikhuluma ngomuthi ofanayo, omane ukhishwe ngezindlela ezihlukile, futhi wehlukile komthamo wento esebenzayo nezinye izinto ezengeziwe ezakha ukwakheka.
I-Actovegin futhi ine-analogues: Cortexin, Vero-Trimetazidine, Solcoseryl, Cerebrolysin nabanye. Kodwa-ke, azikho izifundo ezingafakazela ukuthi enye yale mishanguzo isebenza kakhulu kunenye.
Ukufana
Okujwayelekile kuzo zombili izidakamizwa yinto yazo esebenzayo - Actovegin. Inezakhiwo ezilandelayo:
- kuthuthukisa ukubamba ushukela kanye nomoya-mpilo ezicutshini zomzimba;
- ivuselela umsebenzi wama-enzyme abandakanyeka ezinqubweni ze-oxidative;
- ejwayelekile imetabolism.
Ithinta isistimu yezinzwa ngokuthuthukisa ukuthuthwa kwe-glucose ne-oxygen, okubalulekile ekusebenzeni kobuchopho okujwayelekile. Uma lezi zinto zinganele umzimba, khona-ke umsebenzi wesistimu yezinzwa uyancipha, ama-neurons angafa. Lokhu kuholela ekuthuthukisweni kwe-pathology enjenge-Alzheimer's sifo.
I-Diabetesic polyneuropathy iyinkomba yokusebenzisa zombili izinhlobo zemithamo ye-Actovegin.
Izinkomba zokusetshenziswa kulezi zidakamizwa cishe ziyefana. Lokhu:
- ukungasebenzi kahle kobuchopho, kokubili i-metabolic and vascular in nature (i-ischemic stroke, dementia, ukwehluleka kokujikeleza kwesimo esehlukile), kanye nokubangelwa ukulimala kwe-craniocerebral;
- isifo sikashukela se-polyneuropathy;
- ukuphazamiseka kwemithambo ye-peripheral kanye nezinkinga zazo, kufaka phakathi izilonda ze-trophic kanye ne-angiopathy.
Kulokhu, zombili izindlela zinqunywa njengengxenye yokwelapha okuyinkimbinkimbi, okungukuthi, kanye nezinye izidakamizwa. Ngokuvamile, i-Actovegin isetshenziswa ngokuhlanganiswa nezidakamizwa ze-nootropic eziklanyelwe ukuthuthukisa ukusebenza kobuchopho. Kodwa-ke, nge-polyneuropathy yesifo sikashukela - kanye nezidakamizwa zokunciphisa ushukela wegazi. Ngasikhathi sinye, awukwazi ukuthatha i-Actovegin futhi uphuze imikhiqizo equkethe utshwala.
Ukuxhumana ngezindlela ezahlukahlukene zesidakamizwa nakho kuzokwenzeka. Lokhu:
- hypersensitivity kuzakhi ngazinye ezakha umuthi;
- ukwehluleka kwenhliziyo;
- ukugcinwa kwamanzi emzimbeni;
- izinkinga zokuchama, njenge-anuria noma i-oliguria;
- i-pulmonary edema.
Kunezifo lapho i-Actovegin isetshenziswa ngokuqapha. Lokhu, isibonelo, i-hyperchloremia noma i-hypernatremia. Kepha lokhu kuyasebenza kwizisombululo ezingavinjelwa. Futhi zombili lezi zimo kufanele ziqinisekiswe ngokuhlaziywa. Ukuxilongwa kungabhekwa njengento ephula umthetho uma kunezinkinga zokususa uketshezi emzimbeni.
Ngesikhathi sokukhulelwa nokuqunjelwa, umuthi ubekiwe ngokuqapha. Yize ucwaningo lungazange luveze umphumela ongemuhle kuzingane, umuthi ubekelwa kuphela uma inzuzo engaba khona kumama idlula engcupheni yengane. Ngokuphathelene nokunikezwa umuthi ebuntwaneni, akukho ukuvumelana, isinqumo senziwa udokotela oholayo.
Uyini umehluko?
Kunokwehluka ngisho ekunqumeni izinkomba zokusetshenziswa. Isibonelo, imijovo ye-intravenous iphatha ukulimala kwemisebe esikhunjeni kanye nolwelwesi lwama-mucous ngesikhathi sokwelashwa ngemisebe. Isixazululo sisetshenziselwa ukwelapha amanxeba, ukushiswa, ama-bedores, izilonda zemisuka ehlukahlukene. Amafutha anesilinganiso esifanayo.
Kuzo zombili lezi zinhlobo zomuthi, ukungezwani komzimba kukhonjisiwe njengemiphumela emibi. Lapho usebenzisa izixazululo ezifakelwayo, lezi zivame kakhulu ukubonakaliswa kwesikhumba: ukulunywa, i-urticaria, ubomvu.
Umthamo wento esebenzayo nokutholakala kwehluka. Ngomjovo kanye nokwehla, i-Actovegin ingena emzimbeni ngokushesha okukhulu.
Lapho usebenzisa izixazululo zomjovo, ukubonakaliswa kwesikhumba okungafuneki kungenzeka: ukulunywa, i-urticaria, ubomvu.
Yikuphi okushibhile?
Endabeni yezindlela ezahlukile zokukhishwa kwezidakamizwa, akulungile ngokuphelele ukunquma inkinga yezindleko. Isixazululo somjovo sibiza ama-ruble ayi-1100-1500, kuya ngokuthi umenzi ungubani, inkampani yaseJapan noma inkampani yaseNorway. Imakethe futhi iletha imikhiqizo yezinkinga zase-Austrian.
Izindleko zamaphilisi okupakisha cishe ama-ruble ayi-1,500. Kodwa-ke, ngenxa yomthamo ohlukile, isikhathi senkambo yokwelashwa sizohluka, futhi ngokuya ngamanani angaba ngaphezulu noma aphansi, kuya ngokuthi mangaki imijovo noma amaphilisi ngosuku udokotela ammisele ngalo.
Yikuphi okungcono: amaphilisi noma imijovo i-Actovegin
Ucwaningo luye lwabonisa ukuthi zombili izindlela zokukhishwa kwezidakamizwa zisebenza ngokufanayo. Kepha i-Actovegin esefomini yethebhulethi ivame ukubekelwa iziguli esezikhulile ekwelapheni ukuwohloka komqondo. Ezimweni lapho kudingeka khona ukuthi umuthi usebenza ngokushesha, imijovo iyabekwa, ngoba into esebenzayo ingena egazini ngokushesha.
Kungenzeka yini ukubuyisela imijovo ye-Actovegin ngamathebulethi
Ukuphathwa kwe-Intramuscular kungadala izinhlungu, yize iziguli eziningi zibekezelela umuthi kahle. Kulokhu, kungabekwa ifomu lethebhulethi. Ukushintshwa kungenzeka ngemuva kokuphela kwenkambo yemijovo noma idonsi. Kepha udokotela uthatha isinqumo ngalokhu, ngoba umphumela womuthi ngeke ushintshe, kepha ungahle wehlise ijubane.
Ukubuyekezwa kweziguli
U-Ekaterina, oneminyaka engama-35 ubudala, uTambov: "Lapho bekuba khona ukuphazamiseka kwemizwa ngemuva komkhuhlane, banquma i-Actovegin - okokuqala ngohlobo lwama-droppers, khona-ke kwaba khona inkambo yemijovo. Isebenze kahle, akukho miphumela emibi."
U-Alexander, oneminyaka engama-42, uSaratov: "Babeka i-Actovegin ezifundweni. Ekuqaleni, lapho kunengozi yokuhlaselwa yisifo sohlangothi, babeyimijovo, wabe esephuza amaphilisi. Womabili la mazwe abekezelelekile."
Odokotela babuyekeza ngamaphilisi kanye nemijovo i-Actovegin
U-Elena, udokotela oyi-neurologist, eMoscow: "I-Actovegin izibonakalise eminyakeni eminingi yokuzilolonga. I-ischemia, ukulimala kobuchopho bokulimala, ngiyibeka ngendlela ye-droppers. Ngincoma amaphilisi eziguli esezikhulile ekwelapheni ukuphazamiseka kwemizwa."
UVladimir, udokotela oyi-neurologist, Tver: "I-Actovegin isidakamizwa esisetshenziswe amashumishumi eminyaka, yize ukusebenza kwayo ku-polyneuropathy yesifo sikashukela kufakazelwe muva nje. Zonke izinhlobo zayo zibekezelelwa kahle, ekusebenzeni akukaze kube namacala okukhishwa kwezidakamizwa."
