Le yi-ejenti ye-hypoglycemic esetshenziselwa ukwelapha isifo sikashukela. Umuthi usiza ukuguqula ngokushesha amazinga kashukela egazi futhi uvimbele ukuthuthukiswa kwe-hyperglycemia.
Igama Lezwe elingafanele
INN: i-insulin esebenza ngabantu.
I-Farmasulin yi-ejenti ye-hypoglycemic esetshenziselwa ukwelapha isifo sikashukela.
I-ATX
A10A C01
Khipha amafomu nokwakheka
Kutholakala ngesimo sesisombululo nokumiswa komjovo.
Amaphilisi
Ayitholakali.
Amaconsi
Ayitholakali.
Powder
Ayitholakali.
Isixazululo
Into esebenzayo yesisombululo se-Pharmasulin N yi-biosynthetic insulin 100 IU. Izakhi ezingeziwe zethulwe: i-metacresol, i-glycerin, i-disodium hydrogen phosphate, i-protamine sulfate, phenol, zinc oxide, solution ye-sodium hydroxide namanzi ngomjovo.
I-Suspension H NP iqukethe i-100 IU ye-insulin yezinto eziphilayo kanye nezinto ezengeziwe. Ukumiswa H 30/70 kunokwakheka okufanayo.
Akunandaba nomthamo, kukhiqizwa emabhodleleni engilazi we-5 noma 10 ml, kwiphakethe lamakhadibhodi liqukethe 1 ibhodlela elinjalo. Kumabhilikidi ama-3 ml engilazi, izingcezu ezi-5 inye, ifakwe kwiphakethe ye-contour efakwe kwiphakethe lekhadibhodi.
Akunandaba nomthamo, umuthi uyatholakala emabhodleleni engilazi we-5 noma we-10 ml, kwiphakethe lamakhadibhodi liqukethe 1 ibhodlela elinjalo.
Amakhandlela
Ayitholakali.
Amafutha
Ayitholakali.
Isenzo se-Pharmacological
Ukwakheka kuqukethe i-insulin elawula ushukela. Ngaphezu kokulawula izinqubo ze-metabolic, into esebenzayo ibamba iqhaza kuzo zonke izinqubo ze-anabolic kanye ne-anti-catabolic ezenzeka emzimbeni.
Umphumela wokusetshenziswa kwalesi sidakamizwa wenzeka engxenyeni yehora ngemuva komjovo.
Ngaphansi kwethonya le-insulin yomuntu, ukukhiqizwa kwe-glycogen, glycerin, amanye amaprotheni nama-acid acid asatshalaliswa kwizicubu zemisipha kuyakhuthazeka. Lokhu kwandisa izinga lokuhlanganiswa kwe-amino acid. Kukhona ukwehla kwezinga le-ketogenesis ne-catabolism yezakhi zamaprotheni zemvelaphi yezilwane.
I-Farmasulin N isho insulin ezisebenza ngokushesha. Thola ngokuhlanganiswa kwe-DNA ephindayo.
I-Pharmacokinetics
Umphumela wokusetshenziswa kwalesi sidakamizwa wenzeka engxenyeni yehora ngemuva komjovo. Kuthatha cishe amahora angama-7. Ukuhlaziywa kwe-plasma okuphezulu kakhulu kuqashelwa amahora ama-3 ngemuva komjovo.
Izinkomba zokusetshenziswa
Isetshenziswa njenge-monotherapy yesifo sikashukela i-mellitus, lapho kudingeka i-insulin ukuze umuntu agcine ushukela wegazi. Kunconywe njengokwelashwa kokuqala kwesifo sikashukela esincike ku-insulin. Kuvunyelwe ukubekelwa abesifazane ngesikhathi sokukhulelwa.
Imijovo ye-Pharmasulin H NP ne-H 30/70 isetshenziswa ekwelapheni abantu abanesifo sikashukela sohlobo 1. Zisetshenziselwa futhi ukwelapha i-pathology ye-2, uma ukudla nezinye izisebenzeli zomlomo zinganele.
Contraindication
Ukuphulwa okuqondile ekusebenziseni umuthi yilezi:
- hypersensitivity kuya ku-insulin;
- i-hypoglycemia;
- isifo sikashukela se-neuropathy.
Ngokunakekela
Ngokuqapha, umuthi ubekelwe iziguli ezithola i-beta-blockers, ngoba kulokhu, izimpawu ze-hypoglycemia ziyashintsha noma zimnene. Ukubonisana nodokotela kuyadingeka nakubantu abalimele i-adrenal and thyroid function.
Odokotela bezingane, izingane zivunyelwe ukuzisebenzisa kusukela kuzalwa, uma kunezinkomba ezibalulekile zalokhu.
Ungayithatha kanjani i-Farmasulin?
Isetshenziselwa umjovo ongama-subcutaneous. Ukuphathwa kwe-intramuscular of the drug nako kuvunyelwe. Ukusetshenziswa kwe-intravenous akuvunyelwe ngokuphelele.
Imijovo esetshenziselwa ehlombe yenziwa ehlombe, isicubu sebandla noma isisu sesisu. Imvamisa kufiseleka ukuthi ushintshe indawo yomjovo ukuvikela ukuthuthukiswa kokungathandwa kwasendaweni. Ukunakekelwa kufanele kuthathwe ukuze kuqinisekiswe ukuthi inaliti ayingeni emgodini wegazi ngesikhathi sokufakwa.
Ukufakwa imijovo ehlombe.
Ukumiswa kumakhokhethi ama-3 ml lilinye. Zisetshenziswa kuphela nge-injector foam ekhethekile ebhalwe ukuthi i-CE. Ngokushesha ngaphambi kokuwusebenzisa, umuthi uvuselelwa ngokuhlikihla ikhathishigi ngezandla zezandla. Ngemuva kwalokho iguqulwa cishe izikhathi eziyi-10 kuze kuvele umbala omfushane noma umbala o-milky. Uma umbala owuthandayo ungabonakali, wonke manipulations ayenziwa futhi.
Ungagcini ibhodlela ukuvimba ukwakheka kwegwebu, okuzonqanda ukubalwa okulingene komthamo. Ama-Cartridges akufanele asetshenziswe kabusha. Awukwazi ukuxuba izinhlobo ezahlukahlukene ze-insulin esitokisini esifanayo.
Kwesinye isikhathi kwenziwa imijovo kusetshenziswa amasirinji akhethekile e-insulin. Ukufakwa kunikezwa kuphela ngethamo elibekwe ngokuqinile.
Ngoshukela
Lapho kutholwa i-pathology yesifo sikashukela okokuqala ngqa, kunqunywe isisindo esingu-0.5 U / kg ngosuku. Abantu abanesinxephezelo sikashukela esingagculisi - amayunithi angu-0.7-0.8.
Inkambo esetshenziswayo ye-pathology, abesifazane abakhulelwe nezingane - akukho ngaphezu kwe-2-4 IU ngomjovo owodwa.
Lapho kutholwa i-pathology yesifo sikashukela okokuqala ngqa, kunqunywe isisindo esingu-0.5 U / kg ngosuku.
Imiphumela emibi yeFarmasulin
Ukusabela okuvame kakhulu ukuthuthukiswa kwe-hypoglycemia, izinga elinamandla lakhona okungaboniswa ngokulahlekelwa ukwazi noma isifo sikashukela.
Ukusabela kokungezwani kwasendaweni kungenzeka ngendlela: ubomvu kwesikhumba, i-hyperemia kanye nokulunywa endaweni yomjovo. Kwesinye isikhathi lesi simo kungenzeka singahambisani ne-insulin, imbangela ingaba yizinto zangaphandle ezingaphandle.
Isistimu yomzimba ingenye yemiphumela emibi kakhulu. Iziveza njengesiqubulo sesikhumba, ukushesha komoya, ukuhamba kancane, ukuncipha kwengcindezi yegazi, ukukhuphuka kokujuluka. Lesi simo sisongela impilo. Kulokhu, kufanelekile ukuguqula uhlobo lwe-insulin.
Kwesinye isikhathi i-lipodystrophy ingenzeka endaweni yomjovo. Kuyaqabukela, ukumelana ne-insulin kuba khona.
Umthelela ekhonweni lokulawula izindlela
Ngesikhathi sokulashwa ngeFarmasulin ukunakekelwa okukhethekile kufanele kuthathwe ezimotweni zokushayela nezinye izindlela eziyinkimbinkimbi, njengoba I-hypoglycemia kungenzeka.
Imiyalo ekhethekile
Ngaphambi kokuqala ukwelashwa, udinga ukwenza konke ukuhlolwa komzimba okudingakalayo ukuthola ukuthi umzimba uzolubona kanjani lolu hlobo lwe-insulin. Ingozi ye-hypoglycemia inyuka ngesifo senhliziyo nesemithambo. Ukwehluleka ukulandela ukudla noma umthamo wemithi ophuthelwe kudala i-hypoglycemia enzima.
Sebenzisa ebudaleni
Sebenzisa umuthi ngokuqapha.
Ebudaleni, sebenzisa lesi sidakamizwa ngokuqapha.
Isabelo sezingane
Ukuqapha Kufanele isetshenziswe ngokuqinile ngokuya izinkomba, kusetshenziswa amasirinji angenamfashini. Umthamo kanye nesikhathi sokwelashwa kubalwa kubhekwe nobunzima besimo sengane, kepha hhayi ngaphezu kwama-0.7 amayunithi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuvunyelwe ukuphuza umuthi ngesikhathi sokukhulelwa, kepha ukulungiswa komthamo kuyadingeka ngesikhathi sonke sokukhulelwa.
Umuthi futhi uyasetshenziswa ngesikhathi sokuqunjelwa. Kepha ngalesi sikhathi, udinga futhi ukuqapha ushukela njalo.
Isicelo sokusebenza kokulimala kwezinso
Ukusetshenziswa kwesidakamizwa kuncike ekuthini imvume ye-creatinine.
Sebenzisa umsebenzi wesibindi okhubazekile
Umuthi awusetshenziselwa ukwehluleka kwesibindi okungapheli.
I-Pharmasulin overdose
Ukusetshenziswa kwemithamo ephezulu kubangela isimo se-hypoglycemic. I-overdose ingadalwa ukushintshwa kokudla okunempilo, ukuqina kokuzivocavoca, lapho isidingo se-insulin sincipha, kuleli cala, i-overdose izovusa ukusetshenziswa kwemithamo ejwayelekile. Ukusabela okuvame kakhulu yilokhu: ukukhuphuka kokujuluka, ukwethuka, ukuphefumula komoya.
Ukujuluka okwandayo kungenye yezimpawu zokusetshenziswa ngokweqile komuthi.
Itiye noma ushukela omnandi usetshenziselwa ukwelapha i-overdose. Ezimweni ezinzima, ikhambi le-glucose noma i-1 mg ye-glucagon lifakwa emthanjeni noma emisipha. Uma lezi zinyathelo zingasizi, nikeza ukungeniswa kwe-Mannitol noma i-glucocorticosteroids ukuvikela ukukhula kwe-cerebral edema.
Ukuxhumana nezinye izidakamizwa
Kunemithi ethile engathinta ngqo i-glucose metabolism.
Inhlanganisela ehlanganisiwe
Awukwazi ukuhlangana nezinye izinhlobo ze-insulin, ikakhulukazi imvelaphi yezilwane. Futhi kwenqatshelwe ukuxuba ama-insulin abakhiqizi abahlukile enkambweni eyodwa yokwelashwa.
Akuhlanganisiwe ukuhlanganisa
Ungancomi ukuthatha ngemithi eyehlisa umphumela we-hypoglycemic wokuthatha i-insulin. Lokhu kufaka phakathi: ama-hyperglycemic agents, amanye ama-OC, ama-beta-blockers, i-salbutamol, i-heparin, amalungiselelo we-lithium, ama-diuretics cishe nayo yonke imishanguzo ye-antiepileptic.
Inhlanganisela edinga ukuqashelwa
Ngokuqapha, udinga ukuthatha umuthi ngokuhambisana nama-ejenti we-hypoglycemic womlomo, ama-sulfonamides, ama-salicylates, ama-antidepressants, ama-inhibitors e-ACE kanye ne-MAO, i-enalapril, i-clofibrate, i-tetracyclines, i-anabolic steroid, i-Strofantin K, i-Cyclophosphamide ne-Phenylbutazone.
Umuthi futhi uyasetshenziswa ngesikhathi sokuqunjelwa.
Ukuhambisana notshwala
Musa ukuthatha lo muthi ngotshwala. Lokhu kungaholela ekuthuthukisweni kwe-hypoglycemia kanye nokwanda kwemiphumela emibi.
Ama-Analog
Kukhona izithiyo ezinokwakheka okufanayo noma okunomphumela ofanayo wokwelapha:
- I-Actrapid;
- I-Actrapid MS;
- I-Actrapid NM;
- I-Actrapid NM Penfill;
- Iletin;
- I-Insulrap SPP;
- I-Insuman Rapid;
- I-Intral SPP;
- InsMeral NM;
- I-Monosuinsulin;
- I-Homorap;
- I-Humalogue;
- Humulin Njalo.
Imibandela yekhefu lekhemisi
Umuthi uthengiswa emakhemisi unikezwa umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Kukhishwe.
Intengo yePulasulin
Izindleko kusuka ku-1431 rub. ukupakisha.
Izimo zokugcina zomuthi
Indawo ekahle yokugcina indawo esiqandayo (emazingeni okushisa we + 2-8 ° C), ayibekelwa yiqhwa.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emi-2 kusukela ngosuku lokukhishwa. Ngemuva kokuvula ama-cartridge kanye nezimbiza, ingagcinwa izinsuku ezingama-28 ku + 15 ... + 25 ° C, endaweni eyomile futhi emnyama. Ama-cartridge avulekile akufanele agcinwe esiqandisini.
Umkhiqizi
Inkampani yezokukhiqiza: I-PJSC Farmak, eKiev, e-Ukraine.
Ukusabela kokungezwani kwasendaweni kungenzeka ngendlela: ubomvu kwesikhumba, i-hyperemia kanye nokulunywa endaweni yomjovo.
Ukubuyekezwa mayelana neFarmasulin
U-Irina, oneminyaka engama-34 ubudala, eKiev: "Ngibeke esikhundleni seHumulin ngeFarmasulin. Ngigculisekile ngomphumela. Azikho izikhala ezisheshayo zoshukela, ukuhlaselwa kwe-hypoglycemia akusangikhathazi. Njengoba le insulin ihlanganiswe ngofuzo, ayidingi kucocwa eyengeziwe. Inikezwa kalula. Kunemiphumela emibi embalwa kakhulu" .
UPavel, oneminyaka engama-46 ubudala, uPavlograd: "Umuthi ufanelekile. Akukho ukusabela okungekuhle noma ukushuba kwe-hypoglycemia. Umjovo owodwa owanele ushukela ukuze uhlale uvamile kuze kube ngamahora ayi-12. Ngikholwa ukuthi ikhwalithi iyahambisana nentengo."
U-Yaroslav, oneminyaka engama-52, u-Kharkov: "Imijovo ka-Pharmasulin ifanelekile, kepha kwesinye isikhathi ngizwa ngigula kakhulu. Kuvela ushukela ongafinyeleleki phakathi nosuku. Ngenkathi ngicabanga ukuthi yisiphi isidakamizwa okufanele ngisikhethele enye."
