Ku-mellitus yesifo sikashukela, kusetshenziswa izindlela ezahlukahlukene ukusiza ukubuyisela amazinga kashukela egazini. Lokhu kufaka phakathi iMetamine, enemiphumela emibi kanye ne-contraindication, ngakho-ke kudingeka ufunde imiyalo ngaphambi kokuyisebenzisa.
Igama Lezwe elingafanele
Igama lomhlaba jikelele elingewona ophathelene nalo muthi yi-Metamin.
Ku-mellitus yesifo sikashukela, kusetshenziswa izindlela ezahlukahlukene ukusiza ukubuyisela amazinga kashukela egazini. Lokhu kufaka phakathi iMetamine.
I-ATX
Umuthi unekhodi elandelayo ye-ATX: A10BA02.
Khipha amafomu nokwakheka
Isakhi esisebenzayo somuthi yi-metformin. Ngaphezu kwalokho, kusetshenziswa i-hydroxypropyl methylcellulose, i-povidone, i-silicon dioxide, i-colloidal anhydrous ne-magnesium stearate. Ukukhishwa komuthi kwenziwa ngendlela yamaphilisi ayi-500, 850 ne-1000 mg. Iithebhulethi ezingama-500 no-850 mg zibekwe emqubeni wama-10 ama-pcs. Isixha sekhadibhodi siqukethe 3 ama-blisters. Izibhebhe ze-1000 mg zifakwe kwiphakethe elinezinhlungu ezingama-15 ama-pcs. Kubekwa emaphepheni ama-2 noma ama-6.
Isenzo se-Pharmacological
Ithuluzi liyisidakamizwa se-hypoglycemic, esibonakala ngomphumela we-antihyperglycemic. Ingahlanganyeli ekwakhiweni kwe-insulin futhi ayinakubangela i-hypoglycemia. Into esebenzayo inciphisa ukukhiqizwa kwe-glucose, yandisa ukuzwela kwezicubu zomzimba kuma-insulin futhi inciphisa ukufakwa kweglucose ohlelweni lokugaya ukudla. Ngenxa yokwehliswa kwe-cholesterol ephelele nokuzibandakanya kwe-lipid metabolism, ukusetshenziswa isikhathi eside kwamathebulethi kusiza ukunciphisa isisindo noma ukuligcina lilingana.
Isakhi esisebenzayo somuthi yi-metformin.
I-Pharmacokinetics
Ukufakwa kwesidakamizwa ngokudla kuyancishiswa. Uma ingena emgodini we-gastrointestinal, izinto ziyafakwa, izinga eliphakeme lazo libonwa egazini ngemuva kwamahora angama-2,5. Iningi lazo liphuma nomchamo, inani elincane likhishwa ngemichilo.
Izinkomba zokusetshenziswa
Umuthi ubekelwa lapho kukhona uhlobo 1 nesifo sikashukela sohlobo 2. Isetshenziswa njenge-monotherapy futhi ngaphezu kokwelashwa nge-insulin noma ezinye izidakamizwa. I-Methamine iyasetshenziswa uma kukhona ukukhuluphala okufana noma uma kunesidingo sokulawula ushukela wegazi, kepha lokhu akunakutholwa ngokudla noma ukuzivocavoca. Thatha ngokucophelela umuthi lapho isiguli sihlushwa i-ovary polycystic.
Contraindication
Bayenqaba ukwelashwa lapho:
- ukungabekezelelani ngakunye kwezakhi;
- isifo sikashukela;
- isifo sikashukela sikashukela;
- ukwehluleka okulinganayo kwezinso;
- izinso ezingasebenzi kahle;
- izifo ezithathelwanayo ezinzima;
- ukomisa komzimba;
- ukwehluleka kwenhliziyo okubolile;
- infarction myocardial;
- ukwehluleka ukuphefumula;
- utshwala;
- ukwehluleka kwezinso;
- ubuthi be-ethanol acute.
Ungayithatha kanjani iMetamine
Amacwecwe enzelwe ukuphathwa ngomlomo. Zidliwa ngemuva kokudla ngen umthamo owanele wetshezi. Ezigabeni zokuqala zokwelapha, kusetshenziswa umuthi ongu-1000 mg ngosuku. Ukuze ungabangeli imiphumela emibi, umthamo uhlukaniswe izikhathi ezingama-2-3. Ngemuva kwamaviki ama-2, umthamo ungandiswa. Umthamo omkhulu wansuku zonke akufanele ube ngaphezu kwe-3000 mg.
Ngoshukela
Lapho kunesifo sikashukela, umuthi uphuza ngokungathi sína ngohlelo olusungulwa udokotela ngemuva kokuhlolwa isiguli ngokugcwele.
Imiphumela emibi yeMetamine
Kwezinye izimo, ukusabela okungekuhle kungavela engxenyeni yesikhumba nezicubu ezingaphansi, kanye nezinye izitho ngesimo se:
- i-lactic acidosis;
- ukunambitha ukuphazamiseka;
- isicanucanu
- ukuhlanza
- isifo sohudo
- ukuntuleka kokudla;
- Ubuhlungu esiswini;
- i-hepatitis;
- ushintsho izinkomba zomsebenzi wesibindi;
- komzimba
- ukulunywa
- i-erythema;
- urticaria.
Lapho kwenzeka imiphumela emibi, isidakamizwa siyamiswa.
Umthelela ekhonweni lokulawula izindlela
Nge-monotherapy, imoto ivunyelwe ukushayela izimoto nezinqubo eziyinkimbinkimbi. Ngokuqapha, benza izinto ezidinga ukunakwa okwandayo nokusabela okusheshayo kwe-psychomotor lapho iMetamine ihlanganiswa nezinye izidakamizwa ze-hypoglycemic ngenxa yengozi ye-hypoglycemia.
Imiyalo ekhethekile
Uma isiguli sihlinzile, khona-ke ukuphuza amaphilisi kuyamiswa ezinsukwini ezi-2 ngaphambi kwezinqubo zokuhlinzwa. Ngokungalawulwa kahle kwesifo sikashukela i-mellitus, i-lactic acidosis ingaqala ukusetshenziswa kweMetamine.
Sebenzisa ebudaleni
Ngesikhathi sokwelashwa, iziguli esezikhulile zidinga ukuqapha i-creatinine yegazi, kungadingeka ukulungiswa komthamo.
Isabelo sezingane
Kwenqatshelwe ukusebenzisa umuthi ekwelapheni izingane ngenxa yokushoda kolwazi ngokuphepha kwalo kwalesi sigaba seziguli.
Ucwaningo selukhombisile ukuthi imiphumela emibi yesidakamizwa uma izala ingane ayitholakalanga.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ucwaningo luye lwabonisa ukuthi imiphumela emibi yesidakamizwa ngesikhathi sokubeletha nokuncelisa ibele ayitholakalanga. Ngesifo sikashukela nokukhulelwa, udinga ukulahla ukwelashwa kweMetamine bese ushintshela ku-insulin, esekela izinga loshukela wegazi.
Isicelo sokusebenza kokulimala kwezinso
Ngokuqapha, thatha i-ejenti yomlomo ye-hypoglycemic uma kukhona umsebenzi wezinso ongasebenzi kahle.
Sebenzisa umsebenzi wesibindi okhubazekile
Iziguli ezinenkinga yokusebenza kwesibindi zidinga ukuthatha umuthi ngokucophelela, ngoba i-lactic acidosis ingahle ikhule.
I-Metamine overdose
Uma usebenzisa kabi isilinganiso esinconyiwe somuthi, kungavela i-overdose, okuholela ku-lactic acidosis. Kulokhu, isiguli sidinga ukulaliswa esibhedlela kanye ne-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Lapho uhlanganisa iMetamine nezinye izidakamizwa, ukulungiswa komthamo nokuqinisekiswa kweglucose yegazi kuyadingeka.
Iziguli ezinenkinga yokusebenza kwesibindi kufanele zithathwe ngokuqapha.
Inhlanganisela ehlanganisiwe
Kuyaxutshwa ukuhlanganisa umuthi ne-ethanol.
Akuhlanganisiwe ukuhlanganisa
Ezigulini ezinesifo sikashukela i-mellitus kanye nokwehluleka ukusebenza kwezinso, ubungozi bokuqhamuka ne-lactic acidosis, ebonakala ngokuncipha kwemisipha kanye nokushoda komoya, ngenkathi uthatha izidakamizwa eziqukethe iodine i-radiopaque.
Inhlanganisela edinga ukuqashelwa
Hlanganisa ngokucophelela ukulungiswa kweqembu le-Biguanide nezidakamizwa ze-diuretics kanye ne-hyperglycemic, ezibandakanya i-chlorpromazine, glucocorticosteroids yesistimu noma isenzo sendawo kanye ne-sympathomimetics, ukuze babangele i-ketosis. Ama-inhibitors e-ACE angadala ukuncipha kweglucose yegazi.
Ukuhambisana notshwala
Ngesikhathi sokulashwa, kufanele ugweme ukusetshenziswa kophuzo oludakayo nezidakamizwa eziqukethe notshwala.
Ama-Analog
Uma kunesidingo, buyisela umuthi ngendlela efanayo:
- IFommetin;
- Ifomu;
- I-Bagomet;
- I-Novoformin.
Uchwepheshe ukhetha i-analogue ebheka izici zomzimba nobunzima balesi sifo.
Uchwepheshe ukhetha i-analogue ebheka izici zomzimba nobunzima balesi sifo.
Imibandela yekhefu lekhemisi
Amathebulethi angathengwa kunoma iyiphi ikhemisi uma kunikezwa incwadi kadokotela ochwepheshe.
Ngingakwazi ukuthenga ngaphandle kadokotela
Umkhiqizo awunakuthengwa ngaphandle kokuthola umuthi.
Intengo yeMetamine
Izindleko zeMetamine Sr zincike kwinqubomgomo yamanani ekhemisi nezilinganiso 23-274 UAH e-Ukraine.
Izimo zokugcina zomuthi
Amacwecwe abekwe endaweni emnyama, eyomile futhi engenakufinyeleleka ezinganeni ezinombuso wokushisa ongadluli + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Umuthi ugcina izakhiwo zawo iminyaka emi-3 kusukela ngelanga lokwenziwa kwawo. Lapho usuku lokuphela, isidakamizwa sichithwa.
Umkhiqizi
Umuthi ukhiqizwa yiKusum Farm LLC, e-Ukraine.
Ukubuyekezwa kweMetamine
UValeria, oneminyaka engama-38, uMurmansk: "Ngisebenzise i-methamine ezinyangeni ezimbalwa ezedlule. Angizange ngibe nemiphumela emibi. Ngaphuza isigamu sethebhulethi kathathu ngosuku cishe inyanga. Ngihlelile izindleko, yize ngengeke ngathenga umuthi. Ngi-oda futhi ngalinda cishe isonto. Manje ngizwa kahle "
UPolina, oneminyaka engama-45, uSaratov: "Nginenkinga yesifo sikashukela sohlobo lwe-2. Ngemuva kokuhlolwa ngokugcwele, umuthi wachazwa. Ngosuku lokuqala kusihlwa, kwavela isicanucanu futhi konke kwaphela ngesisu esidabukisayo. Kwakufanele ngenze ezinye izindlela zokwelapha lezi zimpawu ezingezinhle. Angikukhuthazi ukusebenzisa umuthi."
