Umuthi okwehlisa ushukela wokulawulwa ngomlomo unqunyelwe iziguli ezindala nentsha ekwelapheni isifo sikashukela mellitus. Ithuluzi linciphisa ubungozi bezinkinga.
Igama Lezwe elingafanele
INN: metformin; ngesiLatini - Metforminum.
Umuthi okwehlisa ushukela wokulawulwa ngomlomo unqunyelwe iziguli ezindala nentsha ekwelapheni isifo sikashukela mellitus.
I-ATX
A10BA02.
Khipha amafomu nokwakheka
Uhlobo olukhona lokukhululwa ngamathebulethi. Ithebhulethi ngayinye ifakwe kumafilimu. Ukwakheka kuqukethe i-500 mg, 850 mg noma i-1000 mg ye-metformin hydrochloride.
Isenzo se-Pharmacological
Umkhiqizo unomphumela we-hypoglycemic.
I-Pharmacokinetics
Ukuqunjelwa kwenzeka emgungwini wesisu. Ukuqoqwa kwento esebenzayo egazini ifinyelela phezulu ngemuva kwamahora ama-2, nangemva kokudla - ngemuva kwamahora ayi-2,5. Kwesinye isikhathi i-metformin iqongelela izicubu. Kuthululwa emzimbeni wezinso ngosuku lokuqala emva kokuphatha. Ukukhishwa kwezindlu kabusha -> 400 ml / min. Uma kwenzeka ukungasebenzi kahle kwezinso, kudonswa isikhathi eside.
Okunqunyelwe
Umuthi ubekelwe ukungasebenzi kokudla ukunciphisa ukwehla kwe-glucose egazini. Umuthi ukhonjiswa ezigulini ezinesifo sikashukela sohlobo 1 nohlobo 2, kubandakanya nokukhuluphala. Ezinye izidakamizwa zingasetshenziswa ndawonye ukwehlisa ushukela wegazi noma i-insulin.
Umuthi ubekelwe ukungasebenzi kokudla ukunciphisa ukwehla kwe-glucose egazini.
Contraindication
Ngaphambi kokusebenzisa, kubalulekile ukutadisha ama-contraindication. Umuthi awubekelwe iziguli ezinezifo ezithile nemibandela:
- I-hypoxia ngokumelene nesizinda se-anemia, senhliziyo kanye nesehluleki sokuphefumula, ukushaya kwenhliziyo okukhanyayo, ukonakala kokujikeleza kwe-cerebral;
- ukomisa komzimba;
- ukusabela kokungezwani komzimba nesithako esisebenzayo;
- ukusebenza kabi kwesibindi nezinso (okubandakanya amazinga aphakeme we-creatinine);
- ukuba khona kwezifo ezithathelwanayo;
- ukusetshenziswa kabi kotshwala
- ukukhuphuka kokuqina kwemizimba ye-ketone ku-plasma yegazi;
- isifo sikashukela sikashukela;
- i-lactacidemia;
- ukusetshenziswa kokudla okunekhalori ephansi (ekudleni okungaphansi kwe-1000 kcal ngosuku);
- isidingo sokusebenzisa ama-isotopes e-iodine e-radioactive ngesikhathi sokufunda:
- ukukhulelwa
Into esebenzayo idlulela kubisi lwebele, ngakho-ke kufanele uyeke ukondla ngaphambi kokuqala ukwelashwa.
Ngokunakekela
Ngokuqapha, umuthi ubekelwe izingane nasezigulini esezikhulile, kanye nezinkinga nezinso (imvume ye-creatinine - 45-59 ml / min). Uma umsebenzi uhlotshaniswa nokusebenza kanzima ngokomzimba, umthamo kumele uvunyelwe kudokotela.
Ungayithatha kanjani iMetformin Richter
Thatha ithebhulethi yonke ngaphakathi bese uyigeza ngamanzi ahlanziwe.
Ngaphambi noma ngemuva kokudla
Amacwecwe kufanele athathwe ngaphambi kokudla noma ngokudla.
Ukwehla kwesisindo
Ukuze ulahlekelwe isisindo ngemuva kwesifo sikashukela i-mellitus, umthamo kufanele usethwe ngudokotela.
Ngoshukela
Kubekelwe uhlobo 2 lwesifo sikashukela se-500 mg, 850 mg noma i-1000 mg ngosuku. Uma kunesidingo, engeza umthamo ngemuva kwamaviki ama-2. Umthamo omkhulu wansuku zonke yi-3 g noma i-2,5 g ngosuku (ngethamo lama-850 mg). Iziguli asebekhulile azidingi ukuthatha ngaphezu kwe-1 ithebhulethi ngosuku ngomthamo we-1000 mg.
Uma kwenzeka kunenkinga yesifo sikashukela esincike ku-insulin, umuthi unqunywa ngokuya ngohlelo olufanayo, kepha kungafunwa ukuncipha komthamo we-insulin.
Amacwecwe kufanele athathwe ngaphambi kokudla noma ngokudla.
Imiphumela emibi
Umuthi ubekezelelwa kahle yiziguli, kepha imiphumela emibi ingahle ivele.
Amapheshana wesisu
Kukhona isicanucanu, ukuqhaqha kobuhlungu, izihlalo ezikhululekile nokuhlanza. Isiguli singakwazi ukunambitha insimbi emlonyeni wakhe.
Ngasohlangothini lwe-metabolism
Kukhona ukwephulwa kokwakhiwa kwegazi ngenxa yokuntuleka kwevithamini B12 egazini.
Engxenyeni yesikhumba
Isikhumba ukuqhuma.
Uhlelo lwe-Endocrine
Ukwamkelwa kungaholela kusiyezi, ukuncipha kwengcindezi, izinhlungu zemisipha nokukhathala. Imvamisa, lapho umthamo wedluliwe, kuvela i-hypoglycemia.
Allergies
Ukuvuvukala kwesikhumba, ubomvu nokulunywa.
Ukwemukelwa kungadala isiyezi.
Umthelela ekhonweni lokulawula izindlela
Ukuthatha umuthi kwezinye izimo kuholela ekwehleni kwamazinga kashukela. Ukomela, isiyezi, ukunakwa okuphazamisekile kungavela. Ngesikhathi sokwelashwa, kungcono ukwenqaba ukushayela izimoto nokwenza umsebenzi odinga ukunakwa kakhulu.
Imiyalo ekhethekile
Ngokusebenzisa kanyekanye i-insulin ne-sulfonylureas, kuyadingeka ukuqapha izinga likashukela egazini. Ukwelashwa kudinga ukubhekwa njalo kwezokwelapha, kufaka phakathi isimo sezinso, isilinganiso sokuhlushwa kwe-lactate ne-Vitamin B12 ku-plasma yegazi (ikakhulukazi ebuntwaneni nasegugile).
Ungayisebenzisa kanjani iMetformin 1000?
Yini engcono ukuthatha i-Flemoxin Solutab noma i-Amoxiclav?
I-Diaformin isetshenziselwa ukwehlisa i-glucose egazini. Funda kabanzi ngalesi sidakamizwa lapha.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Abesifazane abakhulelwe futhi ababolekayo abayiniki umuthi.
Ukunquma iMetformin Richter ezinganeni
Ingasetshenziswa uma iminyaka isuka eminyakeni eyi-10.
Sebenzisa ebudaleni
Kuyadingeka ukuqapha isimo sezinso futhi ukhethe ngokucophelela umthamo.
Isicelo sokusebenza kokulimala kwezinso
Ukwemukelwa ngaphandle. Ukuqapha kufanele kusetshenziswe lapho imvume ye-creatinine ingama-45-59 ml / min.
Uma izifo ezinzima zesibindi zikhona, umuthi awunqunyelwe.
Sebenzisa umsebenzi wesibindi okhubazekile
Uma izifo ezinzima zesibindi zikhona, umuthi awunqunyelwe.
Ukweqisa
Ukuphuza ngokweqile kwamathebhulethi kuholela ekuphuzweni ngokweqile. Isiyezi, ikhanda, isicanucanu, ukugabha, izinhlungu zemisipha, ukwazi okwenziwe ngeso lengqondo, kuqubuka isisu. Ungamisa izimpawu ze-lactic acidosis usebenzisa i-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Kukhona ukwehla komphumela wokuthatha amaphilisi lapho kuhlangene ne-GCS, ama-hormone e-steroid, ama-estrogens, ama-adrenaline, ama-antipsychotic, ama-hormone egilo.
Ukwehla okukhulu kokuhlushwa kwenzeka ngenkathi uthatha ama-salicylates, i-ACE inhibitors, i-oxytetracycline, i-sulfonylureas, i-acarbose ne-clofibrate derivatives.
Umuthi unokungahambisani kahle ne-coumarin derivatives kanye ne-cimetidine. Lapho uxhumana ne-Nifedipine, i-ejenti ye-hypoglycemic idonswa ngokushesha, kepha ivezwa isikhathi eside emzimbeni.
Ukulungiselela kweCationic kukhulisa ukuhanjiswa kwento esebenzayo ngamaphesenti angama-60.
Lapho uxhumana ne-Nifedipine, i-ejenti ye-hypoglycemic idonswa ngokushesha, kepha ivezwa isikhathi eside emzimbeni.
Ukuhambisana notshwala
Umuthi uvunyelwe ukuhlanganisa ne-ethanol. Ukuphuza utshwala kuholela ku-acidosis yobisi.
Ama-Analog
Faka leli thuluzi ngalezi zidakamizwa:
- Trulicity;
- I-Amaryl;
- Isifo sikashukela;
- UGlidiab;
- Maninil.
Kunezikhalo zento esebenzayo:
- Siofor;
- IGlucophage;
- Glyformin;
- I-Metfogamma.
Ekhemisi ungathola umuthi ngombhalo owengeziwe kwiphakheji:
- I-Zentiva
- Isikhathi eside
- Teva
- Sandoz
- Izinkanyezi.
Ngaphambi kokuthenga, udinga ukwenza isiqiniseko sokuthi azikho izinto zokwaliwa kanye neminye imiphumela engathandeki. Kungcono ukubonana nodokotela ngaphambi kokubuyisela esikhundleni.
Yikuphi okungcono - Metformin noma Metformin Richter
Zombili lezi zidakamizwa zenzelwe ukuthuthukisa isimo seziguli ezine-hyperglycemia. Kulezi zidakamizwa, izingxenye ezisizayo kwimiyalo nabakhiqizi zihlukile, kepha ziyafana ngokusebenza.
Izimo zeholide Metformina Richter ovela ekhemisi
Ikhishwe ngumbhalo.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ikhemisi eliku-inthanethi linga-odwawa ngaphandle kokuthola umuthi.
Zombili lezi zidakamizwa zenzelwe ukuthuthukisa isimo seziguli ezine-hyperglycemia.
Intengo yeMetformin Richter
Intengo yeMetformin Richter eRussia ingama-ruble angama-250.
Izimo zokugcina zomuthi
Ukupakishwa kubekwe endaweni emnyama ngombuso wokushisa ongafinyelela ku + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelf iyiminyaka emithathu.
Umkhiqizi Metformin Richter
UGideon Richter-RUS ZAO (Russia)
Ukubuyekezwa ku-Metformin Richter
Ukubuyekezwa okuhle kukhombisa ukusebenza komuthi, imiphumela esheshayo nokuphepha. Iziguli zehlulekile ukwehlisa isisindo ngesikhathi esifushane zaphendula kabi. Kwezinye izimo, ukubonakala kwemiphumela emibi kuyaphawulwa.
Odokotela
UMaria Tkachenko, udokotela wobuchopho
Lapho uphuza amaphilisi, izinzwa zokuthola i-insulin zanda, futhi ngenxa yalokho, umzimba uqala ukucubungula ama-carbohydrate ngokukhiqiza ngokwengeziwe. Ekwelapheni lesi sifo, udinga ukudla nokuvivinya umzimba njalo. Ukwelashwa okuphelele kuzosiza ukugwema i-hyperglycemia futhi kunciphise nengozi yokuba nezinkinga zenhliziyo.
Anatoly Isaev, umondli
Umuthi usiza ukunciphisa imvamisa ye-gluconeogenesis - ukwakheka kwe-glucose kusuka ezingxenyeni ze-non-carbohydrate (ama-molecule e-organic). Ucwaningo luqinisekisa ukuthi umuthi ubhekana ne-hyperglycemia. Umuthi uyasiza ukunciphisa umzimba, kodwa ekwelashweni okuyinkimbinkimbi. Ngokumelene nemuva lokudakwa okungamahlalakhona, kwenqatshelwe ukuphuza amaphilisi, kufaka phakathi ukwelashwa ngamaconsi.
Iziguli
UKristina, oneminyaka engama-37
Umuthi ungisindise ku-hyperglycemia. Izinga likashukela lalilungiswa ngokujwayelekile ngokuthatha la maphilisi nangendlela yokuphila esebenzayo. Ngithathe i-1 tablet, kwathi ngemuva kwezinsuku eziyi-10 udokotela wandisa umthamo waba ama-2 pcs. ngosuku. Ekuqaleni wazizwa engakhululekile esiswini, ukuqhakaza, isicanucanu. Ngemuva kosuku, izimpawu zanyamalala.
Ukulahlekelwa isisindo
UMarina, oneminyaka engama-29 ubudala
Umuthi ungene esikhundleni sikaSiofor kumkhiqizi "Berlin-Chemie" (Germany). Isenzo sifana, kulula ukuthwala. Ngibona umphumela we-laxative ngemuva kokuthatha nokuthopha. IMetformin yasiza ukubhekana nokugcwala. Ngehle ngamakhilogremu ayi-9 kwezinyanga ezi-4 nengxenye. Isifiso sami sokudla sehlile, futhi ngidla ama-carbohydrate amancane ngenxa yokudla engikudlayo. Ngincoma umuthi.
U-Ilona, oneminyaka engama-46
Ngemuva kokufaka isicelo, ulahlekelwe ngama-8 kg ezinyangeni eziyisithupha. Ingcindezi ibuyele kwesejwayelekile, izibalo zegazi zathuthuka. Inani le-cholesterol embi ne-glucose lehle. Imiphumela emibi, ngaphandle kwesiyezi, ayizange ibone. Ngizoqhubeka nokwelashwa ngomuthi, ngoba kunomthelela, futhi intengo yamukelekile.
