I-Egipentin umuthi osetshenziswa ekwelapheni isithuthwane, sihambisana nokugwazwa okuqinile. Lesi sidakamizwa kufanele sithathwe ngokuqapha ngokweqile futhi kunconywe udokotela kuphela. Akunconyelwe ukusebenzisa umuthi emithanjeni engaphezu kwaleyo ekhonjisiwe emiyalweni yokusetshenziswa.
Igama Lezwe elingafanele
Imithi ye-INN - UGabapentin.
I-Egipentin (Igama lamazwe omhlaba elithi Gabapentin) umuthi osetshenziswa ekwelapheni isithuthwane, sihambisana nokugwazwa okuqinile.
I-ATX
Kuhlukano lwe-ATX lwamazwe omhlaba, umuthi unekhodi N03AX12.
Khipha amafomu nokwakheka
Umphumela we-pharmacological utholakala ngokufakwa kwe-gabapentin kulo muthi. Ngaphezu kwalokho, ukwakheka kwalesi sidakamizwa kufaka i-povidone, i-poloxamer, i-crospovidone, i-magnesium stearate, hydrolase.
Amakhandlela
Lo muthi uyatholakala ngesimo samaphilisi, ngamunye uhlanganisa okungenani i-300 mg yesithako esisebenzayo. Amakhandlela agcwele emabhulini angama-20 ama-pcs. Ama-3 noma ama-6 ama-blits angagcwala ebhokisini lekhadibhodi.
Uhlobo olungekho
Ukukhishwa kwe-Egipentin akuyona ngendlela yamathebulethi, amaphilisi nezixazululo zokulawulwa kwe-intravenous and intramuscular.
Isenzo se-Pharmacological
Isakhi esisebenzayo sinobudlelwano obuthile babameleleli be-inhibitory abakhona ohlelweni oluphambili lwezinzwa. Ngenxa yalokhu, lesi sakhi sinomsebenzi we-anticonvulsant.
Lo muthi uyatholakala ngesimo samaphilisi, ngamunye uhlanganisa okungenani ama-300 mg wengxenye esebenzayo ye-gabapentin.
Into esebenzayo yesidakamizwa ayikwazi ukubopha kwamanye ama-receptors ama-neurotransmitter, kanye nezingxenye ezisebenzayo zezinye izidakamizwa. Naphezu kweqiniso lokuthi ukusebenza komuthi sekufakazelwe, incazelo ephelele yesenzo se-pharmacological ayikanikwa.
I-Pharmacokinetics
Ingxenye esebenzayo ye-Egipentin ingena ngokushesha ezindongeni zendlela yokugaya. Lapho ilawulwa, inani eliphezulu lomuthi osegazini le-plasma litholakala emahoreni angama-2-3 nje kuphela. I-bioavailability yento esebenzayo yesidakamizwa imayelana nama-60%. Ukudla ukudla kanye nokuthatha lesi sidakamizwa akukuthinti ukumunwa kwawo.
I-Exciption ye-Egipentin yenziwa ngenxa yokuqhuma kwezinso. Kulokhu, into esebenzayo ayisebenzi ukuguqulwa kwe-metabolic. Ukuqedwa ngokuphelele kwesithako esisebenzayo kwenzeka ngaphakathi kwamahora amahlanu kuya kwayi-7. Kubantu asebekhulile, ukuqeda ngokuphelele umuthi uvame ukudinga isikhathi eside. IGabapentin ingasuswa ku-plasma yegazi ngesikhathi se-hemodialysis.
Izinkomba zokusetshenziswa
Ukusetshenziswa kwe-Egipentin kuboniswa ngokuthathwa kokuthile okuvela ngokumelene nesizinda somsebenzi okhuphuka kobuchopho. Phakathi kokunye, ukusetshenziswa kwalesi sidakamizwa kunesizathu ekwelashweni kwe-postherpetic neuralgia kubantu abadala. Ekuhlinzweni, ukusetshenziswa kwalo muthi kunesizathu lapho kunezingozi zokuthathwa ngesikhathi sokukhwabanisa.
Contraindication
Awungeke usebenzise lo muthi ekwelapheni iziguli ezinokuzwela okwengeziwe kwento esebenzayo yesidakamizwa.
Ngokunakekela
Ngokuqapha ngokweqile, lo muthi kufanele usetshenziswe ekwelashweni kweziguli okukhona ukwanda kokuwohloka komzimba okungumphumela wokulimala kobuchopho obuhlungu.
Ungayithatha kanjani i-egipentin?
Umuthi wenzelwe ukuphathwa ngomlomo. Uhlobo lomthamo lukhethiwe kucatshangelwa ubulukhuni bokubonakaliswa kwesifo. Ezimweni eziningi, umthamo owanele wama-300 kuye kwangama-600 mg ngosuku wanele ukudambisa izimpawu. Uma kunesidingo, ingakhushulelwa ku-900 mg ngosuku.
Ngoshukela
Ukwelashwa kweziguli ezinesifo sikashukela i-mellitus, ezimweni eziningi, kwenziwa ngemithamo encishisiwe. Imvamisa, isidakamizwa sisetshenziswa kumthamo we-300 mg ngosuku.
Imiphumela emibi yeGibhithe
Ukusetshenziswa kwe-Egipentin kudinga ukuqaphela okwedlulele, ngoba into esebenzayo yalesi sidakamizwa ingadala imiphumela emibi yezimpawu.
Kusuka ezicutshini zemisipha
Ukusebenzisa i-Egipentin kungadala ubuhlungu bokuhlangana. Ezimweni ezingavamile, ngenkathi uthatha umuthi, kubonakala ukuvela kwe-edema nokuqina kwamalunga, i-tendonitis ne-arthritis. Ngaphezu kwalokho, lesi sidakamizwa singadala izimfuno zokuvela kwe-bursitis, contractures yemisipha kanye ne-osteoporosis.
Amapheshana wesisu
I-microbiology yemitholampilo ye-Egipentin injalo ukuthi ngokusebenzisa umuthi njalo, ukusebenza okujwayelekile kohlelo lokugaya ukudla kuyaphazamiseka. Lo muthi ungadala i-stomatitis, i-gastroenteritis, i-glossitis, i-esophageal hernia, i-proctitis, njll. Umuthi ungavusa ukhuphuka kokopha komgudu wokugaya ukudla. Ngaphezu kwalokho, iziguli zivame ukuba nezikhalazo zobuhlungu besisu.
Izitho zeHematopoietic
Ngokusetshenziswa kwe-Egipentin, thrombocytopenia, izimpawu ze-anemia ne-purpura zingavela.
Isistimu yezinzwa ephakathi
Ukusetshenziswa kwe-Egipentin kungavusa ukwehla kwezikhalazo kanye nokwephulwa kokuzwela kwamaqembu emisipha ngayinye. Ngaphezu kwalokho, isakhi esisebenzayo somuthi singadala ukukhubazeka kobuso, ukuphuma kwangaphakathi kanye nokungasebenzi kahle kwensimbi. Ngokuphikisana nesizinda sokusetshenziswa kwe-Egipentin, umuzwa we-euphoria, ama-hallucinations kanye nokuhlaselwa kwengqondo kungenzeka. Ukulimazeka okungenzeka kokuhlushwa, ukulala kwesikhathi sasemini kanye nokuxhumana okulimazayo.
Kusuka ohlelweni lomchamo
Ukuthatha i-Egipentin kungadala i-cystitis kanye nokugcinwa komchamo obukhulu. Ngaphezu kwalokho, umuthi ungavusa ukuthuthukiswa kokwehluleka kwezinso okulimazayo futhi kulimaze nezitho zohlelo lokuzala.
Kusuka ohlelweni lokuphefumula
Ngokusetshenziswa kwe-Egipentin, ukubukeka kokhwehlela kuvame ukubonwa. Ngaphezu kwalokho, lo muthi udala izimo zokubonakala kwe-pharyngitis ne-rhinitis.
Kusuka ohlelweni lwezinhliziyo
Ukuthuthukiswa kwemiphumela emibi kusukela ekuthatheni i-Egipentin ohlelweni lwezinhliziyo kuyinto eqabukela kakhulu. Kulesi simo, kunobungozi be-arrhythmia, vasodilation kanye nokugxuma kumfutho wegazi.
Allergies
Ngasemuva kokuphuza lo muthi, kungavela ukungezwani komzimba, kuvezwe njengokuqhuma kwesikhumba kanye nokuhaywa, ukuvuvukala kwezicubu ezithambile. Ezimweni ezingavamile, ukusabela kwe-anaphylactic kuyabonakala.
Umthelela ekhonweni lokulawula izindlela
Lapho uthola ukwelashwa ne-Egipentin, kunconywa ukulahla ukuphathwa kwezinqubo eziyinkimbinkimbi.
Imiyalo ekhethekile
Lo muthi wenzelwe ukusetshenziswa okuhlelekile. Ukwenqaba okubukhali kokusebenzisa lesi sidakamizwa kungadonsa isibalo sokwanda kwenani lokuthathwa kokwehluleka.
Kuyinto engathandeki ukusebenzisa umuthi lapho kukhona ukubanjwa kokuqina okukhohlisayo, ngoba ukuphumelela kwomuthi kuleli cala kuzoba kuncane.
Sebenzisa ebudaleni
Ubudala obudala akuyona inkambiso yokusetshenziswa komuthi, kepha ukulungiswa kwamthamo kuyadingeka ngokusebenza kwezinso.
Isabelo sezingane
Umuthi ungasetshenziswa ekwelapheni isithuthwane ezinganeni ezingaphezu kweminyaka eyi-12. Kunconywa ukwelapha ama-syndromes ebuhlungu be-neuralgic nalesi sidakamizwa kwiziguli ezineminyaka engu-18 nangaphezulu.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukusebenza nokuphepha kokusebenzisa umuthi ngesikhathi sokukhulelwa nokukhishwa kwesisu akukaze kufakazelwe, ngakho-ke, lezi zimo zingukuphikisana kokusebenzisa i-Egipentin.
Isicelo sokusebenza kokulimala kwezinso
Uma kwenzeka umsebenzi wezinso ungasebenzi kahle, kuyadingeka ukulawula umthamo okhethekile; uma kunesidingo, ukuhlanza umzimba kudinga i-hemodialysis.
Ukweqisa kwe-Egyptina
Uma uthatha i-Egipentin eningi, isifo sohudo sivame ukuvela. I-overdose ingahle ihambisane nokukhishwa. Lapho uthatha umthamo ongaphezu kwama-50 g, ukozela okwandayo kanye nokushisa ngamandla kungenzeka.
Ukuxhumana nezinye izidakamizwa
Ukuphathwa kanyekanye kwe-Egipentin ngama-antacid kubangela ukwehla kokufakwa kwengxenye esebenzayo yesidakamizwa ku-mucosa yendlela yokugaya. Ngaphezu kwalokho, lo muthi ungakhulisa ukugcwala kwe-phenytoin ku-plasma yegazi ngenkathi uyisebenzisa.
Ukuhambisana notshwala
Lapho welapha ngalo muthi, utshwala akufanele buthathwe.
Ama-Analog
Imithi enomphumela ofanayo wokwelapha ifaka:
- Qhubeka.
- Tebantin.
- IGabagma
- Convalis.
- UGabapentin.
- Katena.
- Gapantek et al.
Imibandela yekhefu lekhemisi
Ukuze uthenge umuthi, kudingeka udokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ukuthengisa isidakamizwa ngaphandle kadokotela akukho emthethweni.
Intengo ye-Egipentin
Izindleko zomuthi emakhemisi zisukela kuma-ruble angama-270 kuya kwangama-480.
Izimo zokugcina zomuthi
Gcina umuthi endaweni yokushisa engeqi i-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Ungasigcina isidakamizwa isikhathi esingadluli izinyanga ezingama-36.
Umkhiqizi
Umuthi ukhiqizwa yi-Iberfar-Industry Pharmaceuticals.
Ukubuyekezwa mayelana ne-Egipentin
USvetlana, oneminyaka engama-32, Ukhozi
Bengihlushwa isithuthwane kusukela ngisemncane. Ukuquleka kwakuvame ukwenzeka kaningi, kepha odokotela bacosha leyo mithi base beyeka. Cishe iminyaka emi-3 edlule, wakhulelwa futhi walahlekelwa yingane. Ngokwalesi sizinda, ukuhlukunyezwa kuphinde kwaqala futhi. Udokotela unqume u-Egipentin. Wasebenzise umuthi izinyanga eziyisithupha. Ngigculisekile ngomphumela. Angizange ngibe nemiphumela emibi, kepha kancane kancane inani lokuthathwa lehlile. Ngaphandle kokuthi ukwamukelwa kwezimali kumile, kuze kube unyaka akukho okubambekayo.
UGrigory, oneminyaka engama-26, uVladivostok
Ngazama izidakamizwa eziningi ukuqeda ukuqaqanjelwa. Ukusetshenziswa kwe-Egipentin kunqunywe udokotela. Umuthi lo awungifanele. Kusukela ngosuku lokuqala lokuphatha, imiphumela emibi evela emgodini wesisu yavela. Ubuhlungu besisu, ukugabha, nohudo kungenze ukuthi ngiyeke ukuphuza umuthi.
