I-Amikacin sulfate isetshenziselwa ukwelapha izifo ezithathelwanayo. Umuthi unomphumela we-antibacterial, kepha ungadala imiphumela emibi eminingi, ngakho-ke ungasinaki iseluleko sochwepheshe ngaphambi kokuqala ukwelashwa.
Igama Lezwe elingafanele
Imvamisa udokotela ubhala umuthi wesidakamizwa ngesiLatin. I-Amikacin - igama lezinto ezisebenzayo ze-antibiotic.
I-Amikacin sulfate isetshenziselwa ukwelapha izifo ezithathelwanayo.
I-ATX
I-J01GB06 - ikhodi yokuhlukaniswa kwamakhemikhali okwelapha nokwelapha.
Khipha amafomu nokwakheka
Umuthi lowo usesimweni se-powder emhlophe ukulungiselela isixazululo sokuphathwa kwe-intravenous noma intramuscular.
Umuthi uyatholakala emabhodleleni ayi-10 ml, ngalinye liqukethe 250 mg no-500 mg we-amikacin sulfate.
Isenzo se-Pharmacological
I-antibiotic ingeyeqembu lama-aminoglycosides. Umuthi unemisebenzi ekhethiwe yokulwa nama-microorganisms wegrama-ne-gram-negative aerobic. Ithuluzi aliholeli ekuguqukeni okuhle kwezimpawu zomtholampilo uma abenzeli beso sifo bengama-anaerobes angenagama neprotozoa.
Ingxenye esebenzayo yesidakamizwa ivimba ukwakheka kwamaprotheni kuseli elincane, okuvimbela ukukhula kwenani lamagciwane.
I-Pharmacokinetics
Kungakapheli ihora, ukuqoqwa okuphezulu kwengxenye esebenzayo yomenzeli ekujikelezweni kwe-systemic kuyabonakala.
Kungakapheli ihora, ukuqoqwa okuphezulu kwengxenye esebenzayo yomenzeli ekujikelezweni kwe-systemic kuyabonakala.
Ama-Metabolites akhishwa ndawonye emchameni.
Izinkomba zokusetshenziswa
Umuthi olwa namagciwane unqunywe emacaleni amaningi emitholampilo:
- ukuvuvukala kwe-intraperitoneal (peritonitis);
- sepsis
- ukuvuvukala kokuya esikhathini (meningitis);
- inyumoniya (inyumoniya);
- ukwakheka kwe-purulent exudate emgodleni we-pleural (pleural empyema);
- ukusha okuthelelekile;
- ukutheleleka ngegciwane kwipheshana lomchamo (i-cystitis, urethritis), kufaka nefomu elingapheli lenkqubo yokuvuvukala;
- ukuvuvukala okuhlanzekile kwezicubu (ithumba);
- inqubo ye-purulent-necrotic emgodini wethambo nowamathambo, kanye nezicubu ezithambile eziseduze (osteomyelitis).
Contraindication
Awukwazi ukusebenzisa lesi sidakamizwa emacaleni amaningi anjalo:
- ukungabekezelelani kwe-organic e-amikacin;
- ukukhuphuka okukhulu egazini lemikhiqizo ye-nitrogenous metabolic (i-nitrogen eseleyo) eyachithwa yizinso (azotemia);
- i-pathologically fatigability esheshayo yemisipha ethambile (i-myasthenia gravis).
Ungayithatha kanjani i-amikacin sulfate
Kubantu abadala, umuthi uphathwa ngaphakathi noma ngaphakathi. Umthamo wesithako esisebenzayo ubalwa kanjena: 15 mg we-amikacin ngosuku wehla nge-1 kg yesisindo somzimba wesineke. Umthamo omkhulu wansuku zonke akufanele udlule i-1.5 g.
Inkambo yokwelashwa nge-Amikacin okungenani izinsuku eziyi-7. Uma umphumela wokwelapha ungabonwa ngemuva kwenkathi yesikhathi esithile, khona-ke ukusetshenziswa kwama-antibiotic lelinye iqembu le-pharmacological kufanele kuqale.
Yini futhi kanjani ukuzalela
Ezimweni eziningi, i-sodium chloride enesisindo esingu-2-3 ml noma amanzi ancitshisiwe enzelwe ukujova asetshenziselwa ukulungisa isixazululo.
Isixazululo kufanele sikhishwe ngokushesha ngemuva kokuhlolwa kokuqala kokuzizwa kokuzizwa komuthi.
Ukuthatha umuthi wesifo sikashukela
Ukusetshenziswa kwe-antibiotic yesifo sikashukela akuphikisiwe, kepha kudingeka izeluleko ezikhethekile zokugwema ubunzima.
Cishe zonke iziguli ezithatha ama-antibacterial agents abanzi zibhekene nenkinga yokungalingani kwamagciwane emathunjini.
Imiphumela Emibi ye-Amikacin Sulfate
Kunemikhuba eminingi emibi yomzimba okumele icatshangwe ngaphambi kokuqala ukwelashwa kwezifo.
Amapheshana wesisu
Kwesinye isikhathi kuba nomsebenzi owandayo wama-enzyme wesibindi. Kunezimo ezivame kakhulu zokucasuka kwesitulo nokuhlanza. Kepha ngenkinga yokuphazamiseka kwebhalansi elisesibelethweni, cishe zonke iziguli ezithatha imishanguzo ebanzi ye-antibacterial zibhekana nayo.
Izitho zeHematopoietic
Akuvamile ukuthi kuqhathwe i-anemia ne-leukopenia (ukubalwa kwamaseli amhlophe aphansi).
Isistimu yezinzwa ephakathi
Iziguli zingaphazanyiswa yikhanda nesiyezi phakathi kokuphazamiseka kokusebenza kwe-vestibular. Kukhona ukwephulwa kokucabanga kwamathoni aphezulu (ukungasebenzi kahle kwamazwi), futhi ukulahleka okuphelele kokuzwa nakho kungenzeka.
Akuvamile ukuthi, iziguli zibike ukwephulwa kwe-neuromuscular conduction.
Ngemuva kokuphuza umuthi, iziguli zingaphazamiseka ikhanda.
Kusuka ohlelweni lwezitho zofuzo
Ekuhlulekeni kwe-renal okungapheli, ukwanda kwe-nitrogen eyinsalela kanye nokwehla kokuqalwa kwe-creatinine kuyabhekwa. I-Nephrotooticity iholela ekunciphiseni kwethamo lomchamo (i-oliguria) kanye nokwakheka kwamaprotheni ku-lumen wephephabhuku lomchamo (i-cylindruria). Kepha lezi zinqubo ze-pathological ziyaguqulwa.
Allergies
I-edema kaQuincke ayivelakancane, kodwa ukuqubuka esikhunjeni kuvame ukubonwa, okuhambisana nokulunywa kanzima.
Umthelela ekhonweni lokulawula izindlela
Kuyinto engathandeki ukusebenzisa umuthi wabantu abamisebenzi yabo ihambisana nokuphathwa kwezindlela eziyinkimbinkimbi.
Imiyalo ekhethekile
Kubalulekile ukufunda ngokucophelela imiyalo yokusebenzisa i-antibiotic ukuze ugweme imiphumela emibi.
Ngokuqapha, umuthi wokubulala amagciwane ubekelwe abantu abaneminyaka engaphezu kwengama-65 ubudala.
Sebenzisa ebudaleni
Ngokuqapha, umuthi wokubulala amagciwane ubekelwe abantu abaneminyaka engaphezu kwengama-65 ubudala.
Ukunquma i-Amikacin Sulfate ezinganeni
Umthamo wokuqala ungama-10 mg kg, bese udokotela ebeka u-7.5 mg nge-1 kg yesisindo somntwana njalo emahoreni ayi-12.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Akuvunyelwe ukusebenzisa i-antibiotic kwabesifazane abakhulelwe nangesikhathi uncelisa ibele.
Ukweqisa kwe-Amikacin Sulfate
Uma iziguli zedlula umthamo we-amikacin obekwe udokotela, khona-ke ezimweni eziningi izimpawu ezilandelayo zokudakwa komzimba ziyabonakala: ukuphazamiseka kokuchama, ukugabha, ukulahleka kwezindlebe.
Imvamisa, inqubo ye-hemodialysis iyadingeka ukuqeda lezi zimpawu ezibonakalayo.
Ukuxhumana nezinye izidakamizwa
Kunemithi engaphuzwa kanyekanye ne-Amikacin.
Inhlanganisela ehlanganisiwe
Lapho kuhlanganiswa nama-penicillin, umphumela we-bactericidal we-Amikacin uyancipha.
Musa ukuhlanganisa umuthi ngama-ascorbic acid namavithamini we-B.
Musa ukuhlanganisa umuthi ne-ascorbic acid.
Akuhlanganisiwe ukuhlanganisa
Lapho isetshenziswa ndawonye nama-blocker transmitrate e-neuromuscular kanye ne-ethyl ether, ubungozi bokuphefumula benyuka.
Inhlanganisela edinga ukuqashelwa
Umsebenzi wezinso ongasebenzi kahle ubonakala ngokusetshenziswa kanyekanye kweVancomycin, iCyclosporine neMethoxifluran.
Ukuhambisana notshwala
Kuyenqatshelwe ngokuqinile ukuphuza utshwala ngesikhathi sokulashwa kwe-antibiotic.
Ama-Analog
I-Loricacin ne-Flexelit inomphumela ofanayo wokwelapha.
I-Loricacin inomphumela ofanayo wokwelapha.
Imibandela yekhefu lekhemisi
Umuthi onikezwa imithi uyabiwa.
Amikacin Sulfate Intengo
E-Russia, umuthi ungathengwa ngama-ruble ayi-130-200.
Izimo zokugcina zomuthi
Kubalulekile ukukhawulela ukufinyelela kwezingane ku-antibiotic.
Isikhathi sokuphelelwa yisikhathi
Umuthi ugcina izindawo zawo zokuphulukisa iminyaka emi-2.
Umkhiqizi
Umuthi ukhiqizwa yinkampani yaseRussia Synthesis.
Ukubuyekezwa ku-Amikacin Sulfate
UMaria, oneminyaka engama-24, eMoscow
Kwabulawa umuthi olwa nesifo sokuhlasela kwamaphaphu. Udokotela uxwayise ukuthi ukungasebenzi kahle kwemizwa kungenzeka. Kepha emiphumeleni eminingana eye yabhalwa nguye, wahlangabezana nohudo kuphela. Ngakho-ke, kwakudingeka ukubuyisa ibhalansi yamagciwane kokubili emathunjini nasesitho sangasese sowesifazane. Kepha umphumela wokwelashwa kwezinduna waneliswa.
U-Igor, oneminyaka engama-40 ubudala, eSt
Ngisebenza njengodokotela we-urologist. Nginikeza umuthi olwa nezifo ezithwala izifo zesilisa zohlelo lwezitho zofuzo. Ngithanda iqiniso lokuthi ukululama kwenzeka kungapheli isonto, uma sikhuluma ngenqubo yokuvuvukala ebabazekayo. Kwabesilisa, isifo sohudo sivame ukuvela ngomjovo we-intravenous, kepha ukusetshenziswa kwemikhiqizo yobisi ebilisiwe kuguqula imiphumela enobuthi ye-Amikacin.
UMarta, oneminyaka engama-32, Perm
Umuthi ubekelwe indodana eneminyaka engu-5 ubudala ene-pneumonia etholakele. Ingane yaba nokuhlanza okukhulu. ngakho-ke, imali kwakumele imiswe ngokushesha. Ngikholwa ukuthi izingane zidinga ukunquma izidakamizwa ezingasasebenzi.
