IClindamycin iyinto esebenzayo eyingxenye yemithi ethile eqenjini lama-anti-synthetic antibiotic ochungechunge lwe-linkosamine. Izidakamizwa ezinegama elifanayo zitholakala ngezindlela ezihlukile. Ngokuvamile kubizwa ngephutha ngokuthi yi-gel, i-clindamycin lapho kusebenza njengento esebenzayo.
Ngaphambi kokusebenzisa umuthi oqukethe ingxenye ye-clindamycin, ukubonisana nodokotela nokujwayelana okuningiliziwe nemiyalo yokusebenzisa kuyadingeka.
Amafomu akhona akhishwe kanye nokwakheka
IClindamycin iyatholakala ngalezi zinhlobo ezilandelayo:
- I-Vaginal cream: ihlinzekwa ezikhungweni zezokwelapha nge-tube enabafakizicelo. Ukuqanjwa kufaka isakhi esivele sishiwo esisebenzayo ngaphambili ngendlela ye-phosphate kanye nababizi: i-castor oil, i-propylene glycol, i-sodium benzoate, i-polyethylene oxide-1500, i-emulsifier engu-1. Amafutha anephunga elithile futhi anombala omhlophe noma okhilimu-omhlophe.
- Amakhandlela weGelatin: Athengiswa ama-16 ama-PC. kwiphakethe futhi ube necala elinsomi eline-lid elibomvu. Ukwakheka kwalo muthi kufaka i-hydrochloride yento esebenzayo nezinye izithako ezengeziwe: i-magnesium stearate, i-lactose monohydrate, i-talc, isitashi sommbila.
- Ama-ampoules weglasi anekhambi elicacile noma eliphuzi lokufaka umjovo (v / m no / v): afakwa emaphaketheni epulasitiki abese efaka amakhadibhodi amaphakethe (ama-10 ama-PC ngalinye). Ukwakheka komuthi kuqukethe into esebenzayo.
- Ama-suppositories we-Vaginal: atholakala kumaphakethe weseli (amakhandlela ama-3), afakwe ebhokisini lekhadibhodi. Umuthi lo unesimo se-cylindrical futhi simhlophe noma simhlophe ngombala ophuzi ophuzi.
Ijeli equkethe i-element clindamycin inamagama ahlukile futhi ihlinzekwa ezikhungweni zezokwelapha ezinamashubhu e-aluminium ka-15 noma ama-30. Ukuqina okuphezulu kwengxenye ekhulunywa ngokusetshenziswa kwangaphandle kufinyelela ku-1%.
Imaphi amagugu afaka
IClindamycin iyingxenye yama-gear alandelayo:
- Adapalene;
- I-Dalacin;
- ICopper Wedge;
- Clincitop;
- Clindoxyl;
- IClindacite B Ukwanda;
- Clindacin;
- Clindacin T;
- I-Klindovit;
- Klenzit-S.
IClindamycin iyingxenye yejeli elifana neDalacin.
Isenzo se-Pharmacological
Lapho ivezwa emzimbeni, i-clindamycin isebenza njenge-bacteriostatic. Ingxenye ivimbela ukwakheka kwamaprotheni futhi ixhumane nama-microorganisms athelelanayo futhi anomdlandla: i-anaerobic ne-microaerophilic gram-positive cocci (Clostridium tetani, Mycoplasma spp.), Staphylococcus, bacilli kanye nobunzima obuningi beClostridium perfringens.
Ngokusho kwesibonakaliso se-antimicrobial, le nto ifana ne-lincomycin, kepha kwezinye izimo isebenza ngempumelelo kaningi (izikhathi ezi-2 ukuya kwezi-10).
I-Pharmacokinetics
Ukufakwa kwesithako okunamagama kwenzeka esikhathini esifushane, ngemuva kwalokho kube ne- clindamycin ingena kwezicubu nakulwelo lomzimba.
Ukugcwaliswa okuphezulu kwengxenye egazini nokusetshenziswa komlomo kuyabonakala ngaphakathi kwehora 1, ngomjovo we-intramuscular - ngemuva kwehora eli-1 kumuntu omdala nangemva kwamahora ama-3 enganeni.
Ijeli isetshenziswa ngaphandle, ngakho-ke uma ingena emlonyeni noma emehlweni, ukugeza ngokuphelele ngenani elikhulu lamanzi kuyadingeka.
Esimweni sokuphathwa kwe-intravenous, ukuhlushwa okuphezulu kakhulu kuyaphawulwa ekugcineni kokufakwa. Umuthi ubambezeleka ku-plasma yegazi amahora angama-8 kuya kwayi-12, nempilo yengxenye yamahora angama-2-2,5. Izakhi zemishanguzo zifakwa emzimbeni wesibindi, futhi kungakapheli izinsuku ezi-4 zikhishwe emzimbeni ngokusebenzisa amathumbu nezinso.
Ijeli isetshenziswa ngaphandle, ngakho-ke uma ingena emlonyeni noma emehlweni, ukugeza ngokuphelele ngenani elikhulu lamanzi kuyadingeka.
Ungayisebenzisa kanjani isidakamizwa seChitosan Tiens?
Yiziphi izinkinga zesifo sikashukela sohlobo 1?
Yimaphi amaconsi e-Ciprolet asetshenziselwa - funda kabanzi ngalokhu ku-athikili.
Izinkomba zokusetshenziswa kwe-clindamycin
Imithi equkethe le nto okukhulunywa ngayo ichazwe ngale mibandela elandelayo:
- ukutheleleka kwezitho ze-ENT - imidiya ye-otitis, i-pharyngitis, i-tonsillitis;
- ukulimala kwamathambo kanye nokuhlangana - i-osteomyelitis, isifo samathambo;
- ukutheleleka ohlelweni lokuphefumula - ukuvuvukala kwamashidi we-pleural, inqubo e-purulent -onakalisa enomkhawulo emaphashini, i-bronchitis, inyumoniya;
- amanxeba okuhlanza kanye nokutheleleka kwezicubu ezithambile kanye ne-epidermis - ukuqubuka kwamakhambi, ukuvuvukala okunamandla kwesikhala se-cell, i-furunculosis, i-lesion ye-purulent yeminwe kanye / noma izinyawo, i-erysipelas;
- ukulimala kwezitho zesisu - i-peritonitis, ama-abscesses;
- Izifo ze-gynecological - i-colpitis, i-salpingitis, i-chlamydia, i-adnexitis, i-endometritis, i-neoplasms enobungozi.
Contraindication
Contraindication ukusetshenziswa kwezidakamizwa ze-bacteriostatic zifaka:
- ukungabekezelelani ngakunye kusakhi esisodwa noma ngaphezulu;
- ukungasebenzi kwesibindi noma kwezinso;
- isifuba somoya;
- isilonda, ulcerative colitis;
- isifo se-autoimmune esithinta ama-synapses we-neuromuscular;
- iminyaka efinyelela kwenyanga eyi-1;
- ubudala
- isikhathi sokukhulelwa nokubeletha (ngaphandle kokuthi kusetshenziselwe ngaphandle).
Ungayisebenzisa kanjani i-clindamycin
Ijeli equkethe isithako segama elifanayo isetshenziswa ungqimba oluncane ezindaweni zezinduna nezinduna, ngemuva kokuhlanzwa kwesikhumba.
Umthamo wamaphilisi abantu abadala nezingane ezingaphezu kweminyaka engu-15 unqunywe uchwepheshe wezokwelapha. Ukwelashwa okunconyiwe: 1 pc. Izikhathi ezi-4 ngosuku noma amaphilisi ama-2-3 kumithamo eminingana (lapho kukhona izifo ezinamandla).
V / m no / kwesingeniso:
- abantu abadala: 300 mg izikhathi ezi-2 ngosuku noma i-1.2-2.7 g ngosuku (kuya ngesimo sesiguli);
- izingane ezingaphezu kweminyaka emi-3: 15-25 mg (noma 25-40 mg) ngekhilogremu. Umthamo ophelele usetshenziswa kumakhambi ama-3-4.
Ukuphathwa kwe-intravaginal kwama-suppositories kufanele kwenziwe isikhathi esingu-1 ngosuku ngaphambi kokulala.
Ngoshukela
Ama-antibiotic wesifo sikashukela anqunywa ngemuva kokuhlolwa okudingekayo kwezokwelapha. Imithamo incike esimweni esejwayelekile isiguli kanye nezimpawu zomzimba wakhe.
Imiphumela emibi ye-clindamycin
Akukhiqizwanga ukuthuthukiswa kokusabela okungalungile okuvela emzimbeni.
Kusuka ezicutshini zemisipha
Ukuvela kobuhlungu bezinhlungu obuhlelekile.
Ubuhlungu emuva bungenzeka ngokuthatha umuthi.
Amapheshana wesisu
Ukusuka ohlelweni lokugaya kwezinye iziguli, imiphumela elandelayo emibi iyaphawulwa:
- isicanucanu nokuhlanza
- isifo sohudo kanye nokulimazeka kwesisu;
- izihlakala;
- ukunambitheka kwensimbi (ngemuva kokuphathwa kwemithamo ephezulu yemithi);
- ukuvuvukala kolwelwesi lwe-mucous lwesophagus (lapho usebenzisa amaphilisi);
- i-hyperbilirubinemia;
- ukwanda komsebenzi wama-enzyme wesibindi ne-bilirubin ku-plasma yegazi;
- ukuphazamiseka ekusebenzeni kwesibindi ne-jaundice (akuvamile).
Ukusuka ohlelweni lokugaya ukudla, ezinye iziguli zithola isicanucanu nokuhlanza.
Izitho zeHematopoietic
Ezimweni ezingavamile, kukhona ukwehla kwenani lama-leukocytes, ama-granulocytes e-neutrophilic namaplatelethi egazini.
Kusuka ohlelweni lwezinhliziyo
Ngokuphathwa kwe-intravenous okusheshayo komuthi, umfutho wegazi ungancipha, kubonakale ubuthakathaka nesiyezi.
Allergies
Imiphumela yokungezwani komzimba engenayo ihlanganisa:
- i-urticaria;
- ukwethuka kwe-anaphylactic;
- umkhuhlane
- I-edema kaQuincke;
- ukuvuvukala kwesikhumba nolwelwesi lwama-mucous (ezimweni ezikhethekile);
- erythema multiforme;
- ukwethuka kwe-anaphylactic (akuvamile).
Imiphumela yokungezwani komzimba ebandakanya i-urticaria.
Lapho usebenzisa ijeli, kungahle kuthinte i-dermatitis nemiphumela emibi ehlelekile. Esimweni sokuphathwa kwe-intravaginal, ukusabela okuphambene nezitho ezithinta imizwa kutholakala: isiyezi, i-vertigo.
Umthelela ekhonweni lokulawula izindlela
Ngokubonakaliswa okujwayelekile kwemiphumela emibi ngendlela yokuhlanza, ukungezwani komzimba, isiyezi noma ukuncipha kwengcindezi yegazi, kunconyelwa ukuyeka ukushayela ngesikhathi sokwelashwa.
Imiyalo ekhethekile
Ijeli equkethe isithako esisebenzayo ayinconywa ukuthi ifakwe esikhunjeni ngemuva kokusebenzisa imihuzuko, ngoba lokhu kuzoholela ekucasukeni kakhulu kwesikhumba.
Iziguli ezinezifo zomgudu wesisu kufanele ziqaphele lapho zisebenzisa amaphilisi. Uma kwenzeka isifo sohudo noma izimpawu ze-colitis ngesikhathi sokwelashwa okuqhubekayo, kufanele uthintane nodokotela wakho.
Iziguli ezinezifo zomgudu wesisu kufanele ziqaphele lapho zisebenzisa amaphilisi.
Ebudaleni
Sebenzisa ukuqaphela uma kukhonjisiwe.
Okwezingane
IClindamycin ngesimo sesisombululo ikhonjiswa ekwelashweni kwezingane kusuka eminyakeni eyi-3 ubudala, ngendlela yamakhompiyutha - kusuka eminyakeni eyi-8.
Ngesikhathi sokukhulelwa nokuqunjelwa
Ukusetshenziswa kwe-clindamycin ngesikhathi sokukhulelwa (ukukhulelwa kokuqala) kanye nokuncelisa akukanconywa.
I-Gel yokuqeda izinduna kufanele isetshenziswe ngokuqapha.
Ukweqisa
Uma kwenzeka kusetshenziswa ngokweqile isithako esisebenzayo, imiphumela emibi ingathuthukiswa, ukuqeda lapho kunqunywa khona ukwelashwa okubonakalayo.
Ukuxhumana nezinye izidakamizwa
Umuthi uthuthukisa umphumela wemithi esetshenziselwa ukuphumula izicubu zamathambo. I-Synergism ibonwa ngenkathi kuthathwa isithako esisebenzayo nge-metronidazole, ceftazidime ne-ciprofloxacin.
I-Synergism ibonwa ngenkathi kuthathwa isithako esisebenzayo nge-metronidazole.
Ukusetshenziswa okuhlanganayo ngama-opioid kungaholela ekuvinjelweni komsebenzi wokuphefumula, nangama-sympathomimetics, ama-macrolides ne-chloramphenicol, kube nomphumela ohambisanayo.
Isithako esisebenzayo sinciphisa ukusebenza kwama-aminoglycosides.
Ukuhambisana notshwala
Ukuhlanganiswa kwama-anti-virus notshwala akwamukeleki.
Ama-Analog
Kwi-gynecology, amanye ama-vaginal agents angabekwa esikhundleni se-clindamycin. Phakathi kwazo kukhona:
- I-Dalacin;
- Clindatop;
- Clines;
- I-Klindovit;
- Clindacin.
Kwi-gynecology, i-clindovit ingabekwa esikhundleni se-clindamycin.
Lokhu okulandelayo kuphawulwa njengamaphilisi afanayo ekusebenzeni:
- Klimitsin;
- Dalacin C;
- I-Klindafer;
- I-Pulksipron;
- I-Clindagexal.
Imithi efanayo yemijovo ifaka:
- Dalacin C. Phosphate;
- I-Zerkalin;
- Klimitsin.
Emithini efanayo yemijovo ifaka iZerkalin.
I-generic ephumelela kakhulu yi-Linkomycin.
Imibandela yekhefu lekhemisi
Ukulungiselela okuqukethe isithako esisebenzayo embuzweni kungukubhaliwe.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kunamacala okuthengiswa kwemithi ngaphandle kwemiyalelo kadokotela. Kodwa-ke, ukuzilapha kungaholela emiphumeleni emibi.
Intengo
Izindleko zejeli, ezifaka isakhi esisebenzayo, ziyahlukahluka kusuka kuma-ruble angama-300 kuye kwangama-800. kuya ngomkhiqizi nendawo ethengiswayo.
Izindleko zomuthi emaphaketheni zivela kuma-ruble angama-135, ngesimo samafutha okugcwala kowesifazane - kusuka kuma-ruble angama-350, kuma-ampoules ngesixazululo somjovo - kusuka kuma-ruble ayi-170, ngendlela yama-suppositories - kusuka kuma-ruble angama-500.
Izimo zokugcina zomuthi
Imithi kufanele igcinwe kude namalungu emindeni emincane. Ukushisa komoya okunconyelwe ngu- + 15 ... + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Umjovo kanye nokugcoba kowesifazane sangasese kungasetshenziswa kungakapheli iminyaka emi-2 kusukela ngosuku lokwenziwa komenzi. Amaphilisi, ama-suppositories kanye ne-gel ngesithako esisebenzayo - iminyaka emi-3.
Umkhiqizi
IHemofarm (Serbia) neVERTEX (Russia).
Ukubuyekezwa kodokotela neziguli
UValery, oneminyaka engama-42 ubudala, udokotela oyi-urologist, eMoscow
Nginikeza umuthi wokwelashwa kwe-bacterial vaginosis kwabesifazane kanye ne-anaerobic balanitis emadodeni. Umuthi uyasebenza nge-erythrasma.
UMarina, oneminyaka engama-38, uRyazan
Wathatha i-clindamycin ukuvikela ukuvuvukala ngesikhathi sokwelashwa kwamazinyo. Umphumela uba muhle. Akukho miphumela emibi eye yabonwa. Ukudonswa kwejeli okuwukuphela kwentengo yayo ephezulu.
