Ungayisebenzisa kanjani isidakamizwa iRotomox 400?

I-Rotomox 400 yiqembu lama-antimicrobials. Leli ikhambi elenza into eyodwa. Izibhebhezelwa zenzelwe ukunciphisa ukukhululwa kwento esebenzayo. Umuthi uyasebenza ekulweni nama-microorganisms ayingozi, abonakala ngokumelana namanye ama-antibalaser, ngokwesibonelo, ama-macrolides. Ngokubizwa kwesidakamizwa, umthamo wento esebenzayo (400 mg) ubethelwe.

Igama Lezwe elingafanele

I-Moxifloxacin (Moxyfloxacin)

I-Rotomox 400 yiqembu lama-antimicrobials.

I-ATX

J01MA14 Moxifloxacin

Khipha amafomu nokwakheka

Umuthi ukhiqizwa ngesimo esiqinile. Amathebulethi aqukethe i-400 mg yento esebenzayo. Kulesi sikhundla, moxifloxacin isebenza. Umuthi uqukethe nezinye izinto, noma kunjalo, azikhombisi ukusebenza kwe-antibacterial, kepha zisetshenziselwa ukudala umuthi wokuvumelana okufiswayo. Lokhu kufaka phakathi:

• isitashi sommbila;
• i-microcrystalline cellulose;
• sodium methyl parahydroxybenzoate;
• i-talc;
• i-magnesium stearate;
• i-silicon dioxide colloidal;
• isitashi se-sodium carboxymethyl.

Umuthi unikezwa emaphaketheni aqukethe ama-5 ama-pcs. amaphilisi.

Ungafunda futhi: Imiyalo yokusebenzisa umuthi i-Heinemoks.

Ungayisebenzisa kanjani i-moxifloxacin yesifo sikashukela?

I-Avelox 400 - //saydiabetu.net/lechenie/tradicionnaya-medicina/drygie-lekarstva/aveloks-400/

Isenzo se-Pharmacological

I-Rotomox yi-ejenti elwa namagciwane. Ngokusho kwesigaba, kungokwesigaba se-fluoroquinolones. Isakhi esisebenzayo somuthi (moxifloxacin) siyinto yesizukulwane sesine. Indawo yesenzo saso se-bactericidal ibanzi impela: ama-gram-positive ne-gram-negative microorganisms, ama-bacterium atypical, anaerobic kanye ne-acid. Lesi sidakamizwa sinomphumela omuhle ezimeni ze-pathological, izimpawu zazo ezingeke zisuswe kusetshenziswa ama-macrolides nama-antimicrobial agents wohlobo lwe-beta-lactam.

I-Rotomox yi-ejenti elwa namagciwane.

I-Gram-positive ifaka izinhlobo zama-Staphylococcus aureus (kanye nalezo zinhlayiya ze-pathological ezingamelana ne-methicillin), i-Streptococcus pneumoniae (amagciwane abhekene nokungahambisani nama-penicillin nezidakamizwa zeqembu le-macrolide), i-Streptococcus pyogene (ama-microorganisms kuphela ahlukaniswe yiqembu A). Amagciwane angenayo i-Gram-negative angazinzile ku-moxifloxacin afaka:

• I-Haemophilus influenzae;
• Haemophilus parainfluenzae;
• Klebsiella pneumoniae;
• Moraxella catarrhalis;
• I-Escherichia coli;
• I-Enterobacter cloacae;

Ama-microorganisms e-Atypical: Chlamydia pneumoniae, Mycoplasma pneumoniae. Ngokusebenza, kuyaqinisekiswa ukuthi izinhlayiya ze-pathogenic ezifakwe kuhlu namanye ama-bacterium amaningi azingazinzile kwiRotomox. Kodwa-ke, ukuphepha kokwelashwa nalesi sidakamizwa akuzange kusungulwe.

Umgomo wokusebenza kwesidakamizwa usekelwe ekuvinjelweni kwama-enzyme athile (II no-IV). Ama-Topoisomerases athinta le nqubo. Lawa ma-enzyme abandakanyeka ekwakhiweni kwe-bacterial DNA. Zibuye futhi zisekele inqubo yokulungiswa nokubhalwa. Lapho umsebenzi we-topoisomerases uvinjiwe, kwehla ukujula kokukhiqizwa kwezinhlayiya ze-pathogenic, ngenxa yalokho, izimpawu zesifo ziba ngaphansi.

Umgomo wokusebenza kwesidakamizwa usekelwe ekuvinjelweni kwama-enzyme athile (II no-IV) abathintekayo ekwakheni i-bacterial DNA.

Inzuzo yento esebenzayo ukungabi namandla kokuphambana nezinye izindlela zezinye izinhlobo: ama-macrolides, ama-cephalosporins, ama-aminoglycosides, i-penicillin ne-tetracycline. Uma usebenzisa izidakamizwa zeqembu ezibandakanya i-moxifloxacin (i-fluoroquinolones), okuphambene nalokho, kuba namandla okuphikisana.

Amathuba okulwa namagciwane kwinto esebenzayo yesidakamizwa aphansi. Kulokhu, kuvela izinguquko eziningi kuma-microorganisms. Lokhu kusho ukuthi ukusebenza komuthi ngokusetshenziswa isikhathi eside kungahle kwehle kungekudala. Ezinye izinhlayiya ze-pathogenic ezilwa nezinye izidakamizwa zeqembu le-fluoroquinolone zitholakala ekwelashweni kweRotomox.

I-Pharmacokinetics

Umuthi osebenzayo ekwakhiweni kwalo muthi udonswa ngokushesha. Ngaphezu kwalokho, le ngxenye igxila ngokuphelele. Izinga lokuqina lale nqubo alinciphi ngenkathi kudliwa. Izinzuzo zomuthi zihlanganisa i-bioavailability ephezulu (ifinyelela ku-90%). Into esebenzayo ibopha amaprotheni ku-plasma. Inani le-moxifloxacin elingeqi i-40% yokuqoqwa okuphelele okuhilelekile kule nqubo.

Inani eliphakeme lomsebenzi litholakala emahoreni ambalwa ngemuva komthamo owodwa wephilisi. Umphumela wokwelapha ophakeme kakhulu ubonwa ezinsukwini ezi-3 ngemuva kokuqala kokwelashwa. Into esebenzayo isatshalaliswa kuwo wonke umzimba, kepha ngezinga elikhulu iqongelela emaphashini, i-bronchi, sinuses. Ehlelweni lokusebenzisa umzimba, kukhululwa amakhompiyutha angasebenzi. I-Moxifloxacin ayiguquki futhi ama-metabolites adalulwa ngokusebenzisa izinso ngesikhathi sokuchama nokuwohloka. Umuthi usebenza ngempumelelo ngokulinganayo ekwelashweni kwabesifazane nabesilisa.

Izinga lokuqina lale nqubo alinciphi ngenkathi kudliwa.

Izinkomba zokusetshenziswa

Ngokunikezwa ukuthi into esebenzayo iqoqeka ngezinga elikhulu emaphashini, i-bronchi kanye ne-sinuses, iRotomax inikeza umphumela omuhle kakhulu ekwelapheni izitho zokuphefumula. Kodwa-ke, umuthi ungathola umphumela omuhle ekwelapheni ezinye izimo ze-pathological. Izinkomba ezisetshenziswayo:

• isifo se-bronchitis esingamahlalakhona;
• i-pneumonia (umuthi ubekiwe ngesikhathi sokwelashwa ngesisekelo sokuphuma noma ekhaya);
• izifo zezifo zezitho zomzimba ezivuswa yizinambuzane eziyingozi (umuthi ubekiwe uma kungekho zinkinga);
• ukutheleleka kwesikhumba nezicubu ezithambile;
• sinusitis oyingozi;
• ukutheleleka okuyinkimbinkimbi kwe-intra-isisu.

Contraindication

Umuthi unemikhawulo eminingi yokusetshenziswa, okwehlisa ubukhulu bawo. Lokhu kufaka phakathi:

• ukungabekezelelani komuntu ngamunye engxenyeni eyinhloko yeRotomax (moxifloxacin), noma yimuphi wababekhona;
• ukuqinisekiswa kwesithuthwane;
• isifo sohudo esikhulu;
• ama-pathologies abandakanya ama-tendon nge-quinolone yangaphambilini
• Ukwanda kokuphumula kwesikhathi se-Q-T;
• ukuphazamiseka okuhlukahlukene kohlelo lwezinhliziyo: i-bradycardia, ukuhluleka kwenhliziyo, i-ventricular arrhythmias, kuboniswe ngokungemuva kokwelashwa kwakamuva nge-quinolones;
• I-hypokalemia, ayisebenzi ukuqondiswa.

Ukuxhunyaniswa ngomuthi kufaka ukungabekezelelani komuntu ngamunye engxenyeni eyinhloko yeRotomax.

Ukuxhunyaniswa ngomuthi kufaka phakathi ukuphazamiseka okuhlukahlukene kohlelo lwethambo nenhliziyo.

Ukuthintana nomuthi kufaka phakathi uhudo olunamandla.

Ngokunakekela

Izimo eziningana zokugula, ukwelashwa okudinga ukubhekwa kukadokotela:

• umlando wokuhlaselwa;
• izifo zesistimu yezinzwa ephakathi;
• ingozi ye-cerebrovascular;
• izinguquko ze-atherosulinotic emithanjeni yegazi;
• isifo se-coronary artery;
• ukuphazamiseka kwengqondo;
• isifo sikashukela mellitus;
• i-ventricular arrhythmia;
• I-hypokalemia, i-hypomagnesemia kanye nezinye izimo ezihamba emzimbeni ezihambisana nokungalingani kwe-electrolyte.

Ungayithatha kanjani iRotomox 400?

Kwizifo eziningi, kusetshenziswa irejimeni ejwayelekile yokwelapha: 400 mg kanye ngosuku. Isikhathi sokwelashwa sincike ohlotsheni lwe-pathology:

• i-sinusitis esigabeni esibuhlungu, ukutheleleka okungelula kwelenombolo yangaphandle - isonto eli-1;
• isikhathi esibuhlungu sokukhula kwe-bronchitis esingapheli - izinsuku ezingama-5;
• induna: izinsuku eziyi-7-14;
• ukutheleleka okuyinkimbinkimbi kwe-intra-esiswini: izinsuku ezingama-5-14;
• ukutheleleka kwesikhumba nezicubu ezi-subcutaneous: kusuka ezinsukwini ezi-5 kuye kwezingu-21;
• izifo ezithathelwanayo ngomonakalo wezitho zomzimba we-pelvic - amasonto ama-2.

Nge-sinusitis esigabeni esibuhlungu, umuthi uthathwa isonto eli-1.

Kwi-bronchitis engapheli, isidakamizwa sithathwa izinsuku ezingama-5.

Nge-pneumonia, umuthi uthathwa izinsuku ezingama-7-14.

Ngoshukela

Umuthi uvunyelwe ukusetshenziswa. Qala ukwelashwa nge-regimen ejwayelekile. Uma kungekho ukusabela okungekuhle, ukwelashwa kungaqhubeka ngaphandle kokulandisa inani le-moxifloxacin.

Imiphumela emibi

Ububi bomuthi buningi imiphumela emibi. Imvamisa yabo, kanye nobukhulu, kunqunywa yisimo somzimba, ukuba khona kwamanye ama-pathologies. Kunokwehla kwe-acuity ebonakalayo, ukulahleka kokuzwela kokunambitha.

Kusuka ezicutshini zemisipha

Kunobuhlungu be-etiologies ehlukahlukene okwenziwe ekhaya ngemuva nasemilenzeni. Ukuqhuma kwe-Tendon kungenzeka. Ukubonakala kwe-pathologies efana ne-myalgia, tendonitis, arthralgia, isifo samathambo kuyaphawulwa. Ukwanda kwezibonakaliso zomtholampilo weGravis myasthenia kuyanda.

Amapheshana wesisu

Ubuhlungu besisu, isicanucanu nokuhlanza ngalemuva, ukwanda kwerhasi, izihlalo ezikhululekile noma ezinzima ngokweqile. Ukungasebenzi kwesibindi kungaqhamuka, okuhambisana nokubonakaliswa okuningi: i-jaundice, i-hepatitis egcwele, i-gastroenteritis, umbala wolimi uyashintsha.

Ukuthatha iRotomox 400 kungadala ubuhlungu besisu.

Izitho zeHematopoietic

I-leukocytosis, i-thrombocytopenia, i-leukopenia, i-anemia, i-neutropenia, i-thrombocytosis, i-hyperglycemia, i-hyperlipidemia, ushintsho ekugxambeni kwezinto eziningi, ngokwesibonelo, i-prothrombin, i-thromboplastin, njll.

Isistimu yezinzwa ephakathi

Ukuphazamiseka kwengqondo, ikhanda kanye nesiyezi, ukwehla kwekhwalithi yokulala, ukukhishwa kwemizwa, ukuthamba kwezicubu ezithambile, ukukhubazeka kwenkumbulo, ukudideka, ukuthuthumela emilenzeni, ukukhuluma nokukhubazeka.

Kusuka ohlelweni lwezitho zofuzo

Ubuhlungu esiswini esingezansi, ukuqina kwezinso nokuqina kwesibindi, ukuvuvukala, ukuvuvukala kwezifo zangasese: i-vaginitis, i-candidiasis sangasese.

Kusuka ohlelweni lwezinhliziyo

Shintsha izinga lokushaya kwenhliziyo kanye nemibandela ehambisana nalokhu: tachycardia, arrhythmia. Kukhona ukwanda noma ukwehla komfutho wegazi, ukuboshwa kwenhliziyo, izinhlungu esifubeni, i-tachycardia ye-ventricular kanye ne-tachyarrhythmia.

Ukuthatha iRotomox 400 kungadala i-vaginitis.

Allergies

Izimpawu ze-urticaria: ukuqubuka, ukulunywa. Ukuphendula kwe-Anaphylactic, i-edema kaQuincke, i-necrosis yezicubu kungenzeka.

Umthelela ekhonweni lokulawula izindlela

Umuthi unomphumela omubi ezinhlotsheni eziningi zomzimba, okuvusa ukutholakala kwemiphumela emibi nezinkinga, ngakho-ke akufanele ushayele imoto futhi uhlanganyele kweminye imisebenzi edinga ukunakwa okwengeziwe ngesikhathi sokwelashwa ngeRotomox.

Imiyalo ekhethekile

Ngokuselapha, kunengozi yokulimala kwe-tendon, ngakho-ke uma kwenzeka izinhlungu, udinga ukubukeza irejimeni yokwelashwa bese ushukumisa imilenze ngokushesha.

Abesifazane bathambekele kakhulu emiphumeleni yeRotomox, ngoba imvelo inesikhathi esijana se-Q-T. Lokhu kusho ukuthi izimpawu ezingezinhle ezihambisana nalesi simo zibonakaliswa ngokushesha.

Ngokuhudula okukhulu, i-pseudomembranous colitis ingaqala ukukhula.

Inzuzo yeRotomax ukungabi bikho kokwenza izithombe ngesikhathi sokwelashwa, yize lokhu kusanconyelwa ukugwema ukuvezwa isikhathi eside emisebeni ye-ultraviolet.

Abesifazane bathambekele kakhulu emiphumeleni yeRotomox, ngoba imvelo inesikhathi esijana se-Q-T.

Sebenzisa ebudaleni

Umuthi usetshenziswa ngokuqapha. Kulokhu, leli dosi akufanele liphinde lithathwe uma kubhekwa iminyaka yobudala.

Umuthi kaRotomox wezingane ezingama-400

Ayikho imininingwane ngokusebenza nokuphepha komuthi ekwelashweni kweziguli ezingaphansi kweminyaka engu-18. Ngalesi sizathu, iRotomox ayinqunyelwe kuleli cala.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Kwenqatshelwe ukusebenzisa lesi sidakamizwa ngenhloso yokwelapha abesifazane ngalezo zimo zomzimba.

Isicelo sokusebenza kokulimala kwezinso

Uma kutholakala ukwehluleka kwezinso, iRotomox inqunywa ngokuqapha.

Sebenzisa umsebenzi wesibindi okhubazekile

Kwenqatshelwe ukusebenzisa umuthi uma kutholakala ama-pathologies aqine alesi sitho. Ngokungasebenzi kahle kwesibindi, kanye ne-cirrhosis, inkambo yokwelashwa kufanele yenziwe ngaphansi kokuqondisa uchwepheshe.

Kwenqatshelwe ukusebenzisa umuthi uma kutholakala ukuthi kunesifo esinamandla sesibindi.

Ukweqisa

Imininingwane mayelana nokuvela kokungaphenduki okungekuhle ngokwanda kwenani elinconyiwe lomuthi alanele. Kodwa-ke, uma izinkinga zanda ngenxa yoshintsho lomthamo phezulu ngesikhathi sokwelashwa, ukwelashwa okubonakalayo kwenziwa.

Ukuxhumana nezinye izidakamizwa

Uma iRotomox isetshenziswa kanye nama-NSAIDs, ubungozi bokubanjwa ngamandla bukhuphuka. Ukuphendula okufanayo kungenzeka ngokusetshenziswa kanyekanye kwalesi sidakamizwa nezinye izidakamizwa zeqembu le-quinolone.

Ukufakwa kwe-moxifloxacin kukhubazeka uma kungeniswa imithamo emikhulu yekhabhoni efakiwe emzimbeni, kusetshenziswa imali equkethe amaminerali nama-multivitamini.

Ukusetshenziswa kweWarfarin neRotomax akuholeli ekwakhiweni kwezinkinga, kepha kudinga ukulawulwa kwe-INR.

Esigabeni sokuqala sokwelashwa nge-Digoxin neRotomax, ukusebenza kwabo akukuguquki. Ngokuphathwa okuphindaphindiwe, ukwanda kokuhlushwa komthamo wezinto ezisebenzayo i-Digoxin kuyaphawulwa.

Ukuhambisana notshwala

Akufanele uthathe iziphuzo eziqukethe utshwala nesidakamizwa okukhulunywa ngaso ngasikhathi sinye, ngoba kulokhu, ukubonakaliswa kwemiphumela emibi kuyandiswa.

Enye ye-analogues yeRotomox 400 yi-Abactal.

Enye yezimpawu zesidakamizwa iRotomox 400 yi-Avelox.

Enye yezifanekiselo zeRotomox 400 yiMohlaxia.

Enye yezimpawu zesidakamizwa iRotomox 400 yiMoxifloxacin.

Enye ye-analogues yeRotomox 400 yiZanocin.

Ama-Analog

Izidakamizwa ezingaphansi:

• Moxifloxacin;
• Moflaxia
• I-Avelox;
• Abactal;
• I-Vero-Ofloxacin;
• I-Zoflox;
• I-Zanocin, njll.

Imibandela yokuphumula ye-Rotomox 400 evela ekhemisi

Umuthi yiqembu lemithi kadokotela.

Ngingakwazi ukuthenga ngaphandle kadokotela?

Cha.

Intengo yeRotomox 400

Izindleko ezijwayelekile zomuthi azidluli ama-ruble ayi-520.

I-Rotomox 400 ayinakuthengwa ngaphandle kwemithi.

Izimo zokugcina zomuthi

Ukushisa komoya okwamukelekayo - kufinyelela ku- + 25 ° С.

Isikhathi sokuphelelwa yisikhathi

Ngemuva kweminyaka engu-2 kusuka ngosuku lokukhiqizwa, umuthi awukwazi ukusetshenziswa.

Umenzi weRotomox 400

Belko Pharma, India. E-Russia, ezinye izifaniso zaleli thuluzi ziyenziwa.

Ukubuyekezwa kweziguli mayelana neRotomox 400

U-Eugene, oneminyaka engama-43, u-Perm.

Ngesikhathi sokulashwa ngeRotomox, kwavela isifo sohudo. Ngazama ukushintsha ukudla, ngangenisa imikhiqizo yobisi - konke kwaba yize. Ngeke ngisaqhubeka nokuthatha lo muthi olwa namagciwane.

UValeria, oneminyaka engama-38, uKrasnodar.

Ukwelashwa okukhulu. Wayibona ngezifo zohlelo lwe-genitourinary (indawo ebuthakathaka emzimbeni, imvamisa ihlushwa izifo ezithathelwanayo). Izimpawu azizange zisuke ngokushesha, kodwa kuphela ekugcineni kwenkambo yokwelashwa, kepha ngemuva kokwelashwa angikhumbulanga izinkinga zami zempilo isikhathi eside.

Ukubuyekezwa kodokotela

UPeter I., oneminyaka engama-48 ubudala, otolaryngologist, eMoscow.

Ezimweni eziningi, umuthi ubekezelelwa kahle, imiphumela emibi yenzeka kuphela lapho i-regimen yokwelashwa yephulwa, umthamo wedluliswa, noma ezimweni lapho izifo ezingahambelani nazo zingazange zibhekwe. Ngalezi zizathu, iRotomox isesimweni esihle nochwepheshe.

USerafima A., oneminyaka engama-52 ubudala, udokotela wezokwelapha, i-Izhevsk.

Kuvame ukubekelwa izifo eziningi zohlelo lwezitho zofuzo, isikhumba, ipheshana lokuphefumula.