I-Amikacin-1000 isidakamizwa esilwa ne-antibacterial esingeqembu le-aminoglycoside. Sebenzisa umuthi kuphela njengoba uyalelwe udokotela wakho. Ukuzelapha kungalimaza, kubangele ukonakala enhlalakahleni. Ngaphezu kwalokho, i-analogue ingaba ngcono kumuntu.
Igama Lezwe elingafanele
Igama elingadingekile emhlabeni jikelele lomuthi yi-Amikacin.
I-Amikacin-1000 isidakamizwa esilwa ne-antibacterial esingeqembu le-aminoglycoside.
Ath
Ikhodi yezidakamizwa i-J01GB06.
Khipha amafomu nokwakheka
Umuthi wenziwa ngesimo sempuphu emhlophe, lapho udinga ukulungiselela isixazululo sokuphathwa kwe-intramuscular and intravenous.
Umuthi osebenzayo yi-amikacin sulfate, ongathi ngebhodlela elilodwa ungaba yi-1000 mg, 500 mg noma 250 mg. Izakhi ezisizayo nazo ziqukethwe: amanzi, i-disodium edetate, i-sodium hydrogen phosphate.
Isenzo se-Pharmacological
Umuthi umuthi obulala amagciwane awubanzi. Umuthi unomphumela we-antibacterial, ubhubhisa izinhlobo zamagciwane amelana nama-cephalosporins, ubhubhisa ulwelwesi lwazo lwe-cytoplasmic. Uma i-benzylpenicillin ichazwa kanyekanye ngemijovo, umphumela we-synergistic kwamanye amaqhugwane uyaphawulwa. Umuthi awuthinti ama-anaerobic amancane.
I-Pharmacokinetics
Ngemuva kwemijovo ye-intramuscular, umuthi udonswa 100%. Ingena kwezinye izicubu. Kufika kuma-10% abopha amaprotheni egazi. Izinguquko emzimbeni azivezwanga. Ichithwa yizinso ezingashintshiwe cishe amahora amathathu. Ukuhlushwa kwe-amikacin ku-plasma yegazi kuba ngaphezulu kwamahora 1.5 ngemuva komjovo. Ukucaciswa kabusha kwe-Renal - 79-100 ml / min.
Izinkomba zokusetshenziswa
Le ejenti elwa namagciwane isetshenziselwa ukutheleleka ngegciwane. Kusetshenziswa ezinhlotsheni ezahlukahlukene zokuvuvukala zomgudu wokuchama, izitho zesistimu yezinzwa ephakathi, amathambo, amalunga: i-cystitis, i-urethritis, i-meningitis, i-osteomyelitis, i-pyelonephritis. Isetshenziselwa i-bedores, burns, ukungena kwezifo zezilonda ukungena. Kunqunyelwe i-bronchitis, sepsis, i-pneumonia, i-endocarditis ethelelekile. Ingasetshenziswa ukwelapha i-thrush.
Contraindication
Kwenqatshelwe ukusebenzisa umuthi ukwelashwa ngesikhathi sokubeletha kwengane, ngokuzwela okwengeziwe kwezakhi, ukulimala kwezinso okunzima, kanye nenqubo yokuvuvukala emhlolweni wokuzwa. Ukwephula umthetho okuhlobene nokulingana kungukufaniswa.
Ungayithatha kanjani i-Amikacin-1000
Umuthi ufakwa emzimbeni ngosizo lomjovo. Kufanele uthintane nodokotela wakho ukuze ukhethe uhlobo lokulashwa olufanele noma ufunde imiyalo yomuthi.
Ngaphambi kokuqala kokusebenzisa, kufanele kwenziwe isivivinyo sobuzwela. Ukwenza lokhu, umuthi olwa namagciwane uphathwa ngaphansi kwesikhumba.
Ezinganeni ezineminyaka engaphezu kwenyanga neyabantu abadala, izinketho zemithamo emi-2 zingenzeka: 5 mg nge-1 kg yesisindo somuntu amahlandla ama-3 ngosuku noma ama-7.5 mg nge-1 kg yesisindo somuntu amahlandla ama-2 ngosuku. Inkambo yokwelashwa ihlala izinsuku eziyi-10. Umthamo omkhulu ngosuku ngu-15 mg.
Ezinganeni ezisanda kuzalwa, uhlobo lokwelashwa luyohluka. Okokuqala, banikezwa i-10 mg ngosuku, emva kwalokho umthamo wehliselwe ku-7.5 mg ngosuku. Phatha izinsana isikhathi esingaphansi kwezinsuku eziyi-10.
Umphumela wokwelashwa okubonakalayo nokwesekelayo uvela ngosuku lokuqala noma lwesibili.
Uma ngemuva kwezinsuku ezingama-3-5 umuthi ungasebenzi kahle, kufanele ubonane nodokotela ukuze ukhethe omunye umuthi.
Yini futhi kanjani ukuzalela
Ukuze ulungiselele ikhambi, engeza u-2-3 ml wamanzi kokuqukethwe kwe-vial, uhlanganise kahle, emva kwalokho inhlanganisela ephumayo yethulwe ngokushesha.
Ukuthatha umuthi wesifo sikashukela
Ku-mellitus yesifo sikashukela, akuvamile ukusetshenziswa; kwizifo ezimbi kakhulu, ukulungiswa komthamo ophakanyisiwe kungadingeka.
Imiphumela emibi ye-Amikacin-1000
Ezinye iziguli zibika ngokwenzeka kwezinkinga ezihlukene ngenxa yokwelashwa.
Amapheshana wesisu
Umuntu angahlaselwa isicanucanu, ukuhlanza, i-hyperbilirubinemia.
Izitho zeHematopoietic
I-pathology kungenzeka yezitho ezakha igazi, ukuvela kwe-anemia, i-leukopenia, i-granulocytopenia.
Isistimu yezinzwa ephakathi
Ubuhlungu bekhanda, ukuphazamiseka kokudluliswa kwe-neuromuscular, ukozela, kanye nokukhubazeka kwezindlebe kungenzeka.
Kusuka ohlelweni lwezitho zofuzo
Ukuphazamiseka kwezitho zohlelo lwe-excretory kungabonakala: ukwehluleka kwezinso, proteinuria, oliguria.
Allergies
Isikhumba ukuqubuka, ukulunywa, umkhuhlane, i-angioedema kungenzeka.
Umthelela ekhonweni lokulawula izindlela
Akunconyelwe ukushayela imoto uma imiphumela emibi iphawuliwe: ingaba yingozi kumshayeli nakwabanye.
Imiyalo ekhethekile
Abanye abantu kumele balandele imithetho ekhethekile yokuphuza umuthi.
Sebenzisa ebudaleni
Ukuqapha kufanele kuvikelwe lapho uthatha umuthi. Ukwamkelwa kokwelashwa okunjalo kunqunywa ngawodwana. Nge-myasthenia gravis ne-parkinsonism, umuntu kufanele aqaphele ikakhulukazi.
Ukunquma i-Amikacin-1000 ezinganeni
Umuthi ungabekelwa izingane uma inzuzo yokwelashwa idlula ukulimala okungenzeka. Kuze kube yiminyaka eyi-6, umuthi unqunywe kumthamo ohlukile.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ibekelwe abesifazane abakhulelwe kuphela kulezo zimo lapho impilo yowesifazane incike ekuphuzeni umuthi. Kwezinye izimo, kufanele kungafakwa ohlelweni lokwelapha ngenxa yemiphumela enobuthi ku-fetus. Kuyenqatshelwe futhi ngesikhathi sokukhawulwa.
Ukweqisa kwe-Amikacin-1000
Uma kwenzeka kuba ne-overdose, i-ataxia, iziguli ziyaboma, zomile. Ukuqhuma, ukuphazamiseka kokuchama, ukukhala ezindlebeni, ukwehluleka ukuphefumula kuyaphawulwa.
Kufanele ushayele i-ambulensi.
Ukuxhumana nezinye izidakamizwa
Ngokusetshenziswa kanye kanye neminye imithi, ukusabela okungekuhle kungenzeka. Kunconywa ukusebenzisa izimonyo, izixazululo zamalensi wokuxhumana ngokuqapha ngesikhathi sokwelashwa.
Inhlanganisela ehlanganisiwe
Kulesixazululo, awukwazi ukuhlanganisa isidakamizwa ne-potasium chloride, ama-penicillin, ama-ascorbic acid, amavithamini e-B, i-Chlorothiazide, iHeparin, i-Erythromycin.
Akuhlanganisiwe ukuhlanganisa
Akunconyelwe ukusebenzisa lapho usebenzisa i-ethyl ether, blockers yokuhambisa i-neuromuscular, ngoba ubungozi bezinkinga banda.
Lapho uxhumana ne-carbenicillin nezinye izidakamizwa ze-penicillin, i-synergism iyenzeka.
Inhlanganisela edinga ukuqashelwa
Nge-cyclosporine, i-methoxyflurane, i-cephalotin, i-vancomycin, ama-NSAID, sebenzisa ngokuqapha, ngoba amathuba okukhula nezinkinga ze-renal ayanda. Ngaphezu kwalokho, uthathe ngokucophelela nge-loop diuretics, cisplatin. Ubungozi bezinkinga banda ngenkathi uthatha ama-he hetatic ejenti.
Ukuhambisana notshwala
Kuyenqatshelwe ngokuphelele ukuphuza utshwala ngesikhathi sokwelashwa.
Ama-Analog
Analogs ayatholakala njengesixazululo. Izindlela ezisebenzayo yi-Ambiotik, uLorikacin, uFlexelit.
Imibandela yekhefu lekhemisi
Ngaphambi kokuthenga, kufanele uthintane nodokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Akunakwenzeka ukuthenga umuthi uma udokotela engayalethanga.
Intengo ye-Amikacin-1000
Izindleko zesidakamizwa cishe ngama-ruble angama-125-215. ukupakisha.
Izimo zokugcina zomuthi
Umuthi onikezwe umuthi kufanele ugcinwe ngaphandle kwezingane endaweni emnyama neyomile. Izinga lokushisa lingafika ku-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Umuthi ufanele iminyaka emithathu.
Umkhiqizi
Umuthi lo ukhiqizwa eRussia.
Ukubuyekezwa kwe-Amikacin 1000
UDiana, oneminyaka engama-35, uKharkov: "Udokotela uchaze umuthi ukuthi welashwe i-cystitis. Wathatha neminye imishanguzo namakhambi abantu ngasikhathi sinye. Kwasiza ngokushesha, wabona ukukhululeka kusukela ngosuku lokuqala. Umuthi uyasebenza futhi awubizi."
UDmitry, oneminyaka engama-37, uMurmansk: "Wayephatha i-Amikacin nge-pneumonia. Iyasiza ngokushesha izidakamizwa ezisebenzayo, yize kungathandeki ukujova kabili ngomjovo wosuku. Kujabulisile futhi kuyizindleko eziphansi."
