Umuthi uMikardis wehlisela umfutho wegazi, ngakho-ke umthwalo osenhliziyweni uyancipha. Umphumela walesi senzo ukunciphisa ingozi yokuhlaselwa yisifo senhliziyo kanye namathuba okufa. Kodwa-ke, ngaphambi kokuqala ukwelashwa, isiguli kufanele sizijwayeze nomuthi, ngoba unezici.
Igama
Imithi ye-INN - iTelmisartan.
Umuthi uMikardis wehlisela umfutho wegazi, ngakho-ke umthwalo osenhliziyweni uyancipha.
Igama ngesiLatini nguMicardis.
I-ATX
Ikhodi ye-ATX yi-C09CA07.
Khipha amafomu nokwakheka
Uhlobo lwethebhulethi lomuthi luqukethe 40 mg noma 80 mg we-telmisartan, esetshenziswa njengento esebenzayo. Ababizi yilezi:
- i-sorbitol;
- i-caustic soda;
- i-magnesium stearate;
- i-povidone;
- i-meglumine.
Umuthi uyatholakala ngesimo sethebhulethi.
Isenzo se-Pharmacological
Izibhebhe zeMikardis izidakamizwa ze-antihypertensive. Amaphilisi womuthi anemiphumela elandelayo:
- block angiotensin 2 receptors;
- ukunciphisa inani le-aldosterone egazini;
- ingcindezi ye-diastolic ne-systolic ephansi.
Umuthi ubonakala ngokungabi bikho kwesifo sokuhoxiswa futhi akusithinti kabi isilinganiso senhliziyo.
Amatafula kaMikardis aphansi we-diastolic ne-systolic blood pressure.
I-Pharmacokinetics
Izici ze-Pharmacokinetic zomuthi:
- ukubopha kumaprotheni egazi - 99%;
- ukumuncwa ngokushesha;
- ukuhlushwa kwegazi (esiphezulu) - ngemuva kwamahora ama-3;
- ukumbiwa okuvela emzimbeni - kwenziwa kusetshenziswa izinso.
Izinkomba zokusetshenziswa
Umuthi usetshenziselwa umfutho wegazi ophakeme. Ngaphezu kwalokho, leli thuluzi lihloselwe ukwehlisa amathuba okuba nezifo zesistimu yezinhliziyo nokunciphisa ukufa kwabantu.
Umuthi usetshenziselwa umfutho wegazi ophakeme.
Contraindication
Contraindication yilezi:
- ukuzwela okuphezulu kwe-fructose;
- izinhlobo ezinzima ze-pathologies zesibindi;
- hypersensitivity kwezidakamizwa;
- ukunganele kwe-isomaltase ne-sucrase;
- izifo zepheshana elihlanganisayo, zenzeka ngendlela evimbela ukuhlangana;
- ukwephulwa kokufakwa kwe-galactose ne-glucose.
Izimo ezilandelayo zidinga ukusetshenziswa ngokucophelela komuthi:
- isikhathi sokusebenza ngemuva kokudluliselwa kwezinso;
- ukuncipha kokujikeleza umthamo wegazi ngemuva kokusebenzisa i-diuretics;
- i-hyperkalemia ne-hyponatremia;
- ukungasebenzi kahle kwesibindi nezinso;
- I-stenosis: imithambo yezinso, imvelo ye-subaortic hypertrophic, ama-mitral kanye nama-valve we-aortic.
Ngokuqapha, umuthi kufanele uthathwe uma kwenzeka wehluleka izinso.
Ungayithatha kanjani
Umuthi uphuza ngomlomo. Ukusetshenziswa kwesidakamizwa kuzimele kokudla.
Kwabadala
Iziguli zabantu abadala zinqunyelwe ukuthatha umuthi isikhathi esisodwa ngosuku ngenani lama-40 mg. Uma kunesidingo, shintsha umthamo, inani lomuthi lenyuka laya ku-80 mg.
Okwezingane
Umuthi awusetshenziswanga ezinganeni, ngoba uthelelezelwa ezigulini ezingaphansi kweminyaka engu-18.
Umuthi awusetshenziswanga ezinganeni, ngoba uthelelezelwa ezigulini ezingaphansi kweminyaka engu-18.
Kungenzeka yini ukuba wabelane
Ukwahlukanisa i-capsule ezingxenyeni eziningana akunconywa.
Kungenzeka yini ukuthi uphuze umuthi onesifo sikashukela
Ngesikhathi seshukela, umuthi uthathwa ngemvume kadokotela.
Imiphumela emibi
Uma uthathwa, ukuthuthukiswa kokungaphenduki okuhle kungenzeka.
Amapheshana wesisu
Ukusuka ohlelweni lokugaya ukudla, kunezimpawu zemiphumela emibi:
- umlomo owomile
- ukungakhululeki esiswini nokungajabuli;
- umsebenzi owengeziwe wama-enzyme wesibindi;
- ukuthopha;
- isifo sohudo
Ukusuka kwipheshana lesisu, umlomo owomile ungavela njengomphumela oseceleni.
Kusuka ohlelweni lwezinhliziyo
Iziguli zakha ukubonakaliswa okulandelayo:
- ukukhuphuka kwenhliziyo;
- umfutho wegazi ophansi;
- i-bradycardia;
- uhlobo lwe-orthostatic hypotension.
Isistimu yezinzwa ephakathi
Isimo sesiguli sibonisa ukubonakaliswa okufakwe kuhlu:
- Ukudana
- ukwehluleka njalo;
- ukukhathazeka
- ukuphazamiseka kokulala;
- isiyezi.
Umphumela wecala lesistimu yezinzwa ephakathi ungaba ukukhathazeka.
Kusuka ohlelweni lomchamo
Isiguli singaba nokuhluleka kwezinso, ukusebenza kahle kwesitho, kubandakanya i-oliguria.
Kusuka ohlelweni lwe-musculoskeletal
Ukuphendula okungahambi kahle kuholela kwizimpawu ezifanayo:
- izinhlungu emisipha, amalunga nemisipha;
- ukugoba ngenxa yokuqina kwemisipha.
Uma usebenzisa umuthi, kubuhlungu izinhlungu emisipha - lokhu kungumphumela ongemahle.
Kusuka ohlelweni lokuphefumula
Imiphumela emibi ibhekwa njengokuphefumula komoya.
Allergies
Ukuthatha umuthi kungaholela kulezi zimpawu ezilandelayo:
- ukulunywa
- imichilo yesimo esinobuthi;
- i-angioedema ngengozi eyengeziwe yokufa;
- umkhuhlane we-nettle;
- erythema.
Lapho uphuza umuthi, ukuqhuma kohlobo lobuthi kungavela.
Imiyalo ekhethekile
Kuyadingeka ukulawula ukuqoqwa kwe-potassium lapho uthatha i-ejenti enezithako eziqukethe i-potassium kanye ne-potassium-sparing diuretics.
Uma umsebenzi wezinso nethoni ye-vascular kuncike ohlelweni lwe-renin-angiotensin-aldosterone, khona-ke ukusetshenziswa kweMikardis kungaholela kokuqukethwe okwengeziwe kwe-nitrogen esegazini (hyperazotemia), ukwehla kwengcindezi, noma uhlobo olubi lokunganele.
Ukuhambisana notshwala
Umuthi awuhlanganisiwe notshwala. Uma ngesikhathi sokwelashwa isiguli sizophuza utshwala, kuzoba nomphumela onobuthi, ozoholela ekuphenduleni okubi.
Umuthi awuhlanganisiwe notshwala.
Umthelela ekhonweni lokulawula izindlela
Ukuthatha uMikardis kungaholela ezenzweni ezingezinhle ezithinta ukusebenza kohlelo lwezinzwa oluphakathi. Lokhu kunomthelela ekuwohlokeni kokuhlushwa, okuthinta kabi ukuphathwa kwezokuthutha.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ama-blocker ama-receptor ama-Angiotensin kuwo wonke ama-trimesters aqinisekiswe ukusetshenziswa, ngoba leyo mithi ibonakala nge-fetotoxicity. Ngesikhathi sokuncelisa, umuthi awunqunyelwe.
Ngesikhathi sokukhulelwa nokuqunjelwa, umuthi awukwazi ukusetshenziselwa ukwelashwa.
Ukweqisa
Uma umthamo ovumelekile udluliwe, i-bradycardia, i-tachycardia kwenzeka futhi ingcindezi iyancipha.
Ukuxhumana nezinye izidakamizwa
Ukusetshenziswa kweMikardis nezinye izidakamizwa kuholela emiphumeleni elandelayo:
- Ama-NSAIDs - imiphumela yomuthi iyancishiswa, umsebenzi wezinso uvinjelwe, ubungozi bokuthola ukuhluleka kwe-renal bukhuphukile;
- imithi equkethe i-lithium - umphumela onobuthi;
- ukuphathwa kanyekanye kwe-telmisartan ne-Digoxin, Paracetamol, Ibuprofen, Hydrochlorothiazide, Glibenclamide - akukho zenzo eziyingozi;
- izidakamizwa zokunciphisa umfutho wegazi - kwandisa ukusebenza kwezokwelapha.
Lapho usebenzisa iMikardis ngezidakamizwa ukwehlisa ingcindezi, ukusebenza ngempumelelo kwezokwelapha kuyenyuka.
Ama-Analog
Izidakamizwa ezilandelayo ziyafana ukusebenza:
- IMikardis Plus umuthi we-hypotensive equkethe i-hydrochlorothiazide ne-telmisartan.
- INortian yi-angiotensin 2 receptor blocker ebonakala impahla ye-vasoconstrictor.
- I-Candesar yisidakamizwa esisetshenziselwa ukwehluleka kwenhliziyo kanye nomfutho wegazi ophakeme.
- I-Presartan ingumuthi onempahla ye-antihypertensive. Ifomu lomthamo limelelwa ngamathebulethi.
- I-Teveten ngumenzeli we-hypotensive. Ngaphezu kwalokho inomphumela we-vasodilating ne-diuretic.
- I-Atacand isidakamizwa esivamile esiqukethe i-candersartan njengesithako esisebenzayo.
- I-Candersartan ingumuthi waseRussia okhethe i-angiotensin receptor blocker.
Imibandela yekhefu lekhemisi
Kudingeka iresiphi.
Malini uMikardis
Intengo - ama-ruble angama-500-800.
Izimo zokugcina zomuthi
Umuthi kufanele ube sendaweni eyomile. Umuthi kumele uvikeleke ekuchayeni elangeni.
Isikhathi sokuphelelwa yisikhathi
Ngokuya ngemiyalo esetshenziswayo, umuthi unokuphila eshalofini kweminyaka emi-4.
Ngokuya ngemiyalo esetshenziswayo, umuthi unokuphila eshalofini kweminyaka emi-4.
Ukubuyekezwa mayelana neMikardis
Ukubuyekezwa kuqukethe imibono eyehlukene yabodokotela neziguli mayelana naleli thuluzi.
Izazi zezenhliziyo
Elena Nikolaevna
Ngenxa yezifundo, kwatholakala ukuthi ukuthatha uMikardis ngempumelelo kunciphisa ingcindezi. Ngaphezu kwalokho, lo muthi unomphumela omuhle isigqi senhliziyo yeziguli zeminyaka ehlukile. Amathuba okuphendula okuphansi aphansi, okwenza ukusetshenziswa kwomuthi kuphephe.
U-Albert Sergeevich
Ukwemukelwa kweMikardis kuboniswa kwiziguli ezine-hypertension ye-arterial. Ngokuya ngezincomo kanye nomthamo ofanele, umkhiqizo awubangeli ukusabela okubi. Isenzo sihlala kusuka emahoreni ayi-12 kuye ezinsukwini ezi-2.
Iziguli
U-Antonina, oneminyaka engama-48, eNovosibirsk
Udokotela unikeze ukusetshenziswa kweMikardis ngenxa yomfutho wegazi ophakeme. Umuthi awuzange uholele ekuwohlokeni inhlala-kahle. Umphumela omuhle waphakama ngemuva kwemizuzu engama-20-30 futhi wahlala kuze kube ngakusasa ekuseni.
U-Oleg, oneminyaka engama-46, uTomsk
Umuthi wabekwa ngemuva kokuhlaselwa yisifo senhliziyo. Ngosizo lukaMikardis, wakhipha wonke umfutho wegazi ophakeme nesiyezi. Kwadlula unyaka, kepha ikhambi alizange lehlule ngalesi sikhathi. Umzuzu kuphela, ngenxa yokuthi ebengingafuni ukuthenga umuthi, umelwa yizindleko ezinkulu.
U-Alena, oneminyaka engama-52, u-Ulyanovsk
Ngihlupheka isikhathi eside ngenxa yezinhlungu ekhanda kanye nomfutho wegazi ophakeme. Udokotela wanquma ukwelashwa ngosizo lukaMikardis. Umuthi kufanele uphuzwe kwithebhulethi ngosuku, futhi ephaketheni kukhona ama-pcs ayi-14. Ngikuthandile ukuthi izinsuku zesonto lapho ungadabula khona ngenkathi uthatha umuthi zikhonjisiwe egqumeni. Ngenxa yalokhu, ingcindezi ijwayelekile, kepha kwesinye isikhathi kuba nemizwa engajwayelekile esiswini.
