ISiofor 850 ijwayele ukusetshenziselwa ukukhipha isisindo ngokweqile bese wehlise isisindo, kanye nokwelashwa kwesifo sikashukela. Ukwakheka okuphephile nentengo efinyelelekayo emakhemisi kwayenza kwaba umuthi odumile kakhulu.
Igama Lezwe elingafanele
I-Metformin.
ISiofor 850 ijwayele ukusetshenziselwa ukukhipha isisindo ngokweqile bese wehlise isisindo, kanye nokwelashwa kwesifo sikashukela.
I-ATX
A10BA02.
Khipha amafomu nokwakheka
Indlela yokukhishwa kwesidakamizwa ngamathebulethi ayi-0,5 g wezinto ezisebenzayo (metformin hydrochloride). Njengoba izinto ezisizayo yilezi:
- i-magnesium stearate;
- i-povidone;
- i-hypromellose;
- i-macrogol.
Indlela yokukhishwa kwesidakamizwa ngamathebulethi ayi-0,5 g wezinto ezisebenzayo (metformin hydrochloride).
Isenzo se-Pharmacological
Ingxenye esebenzayo yesidakamizwa yi-biguanide, enomphumela we-antihyperglycemic. Umuthi unciphisa ukugxila kwe-glucose glucose, awusebenzi ukukhiqizwa kwe-insulin futhi ayivusi i-hypoglycemia.
Ithuluzi lithuthukisa ukukhiqizwa kwama-glycogen ngaphakathi kwezakhi zezicubu nokuhanjiswa kwamaprotheni eglucose.
Njengomphumela, umuthi uvamisa amazinga eglucose, ukuthuthukisa i-lipid metabolism, ukwehlisa i-cholesterol kanye nokugxila kwe-triglyceride.
Umuthi unciphisa ukugxila kwe-plasma kashukela (ushukela).
I-Pharmacokinetics
Umuthi udonswa umgudu wokugaya ukudla. Ukuhlushwa okuphezulu kufinyelela ngemuva kwamahora we-2-2,5.
Ukudla kuvimbela ukumuncwa kwalesi sidakamizwa.
Into esebenzayo inamandla okuqongelela ezinso, isibindi, izicubu zemisipha kanye namathe. Ingena kulwelwesi lwe-erythrocyte.
Umuthi ophuma emzimbeni ukhishwa yizinso zingashintshiwe. Ukuphila kwesigamu kusuka emahoreni ayisithupha kuya kwayi-7.
Izinkomba zokusetshenziswa
- thayipha i-2 isifo sikashukela ngokungabikho komphumela omuhle ovela ekusebenzeni ngokomzimba nokudla (ikakhulukazi ezigulini ezinokukhuluphala);
- umuthi ungahlanganiswa ngokuhlanganiswa nama-insulin kanye nama-ejenti we-hypoglycemic.
Inkomba yokusetshenziswa kohlobo 2 lwesifo sikashukela ngokungabikho kwemiphumela emihle evela ekusebenzeni komzimba nokudla.
Contraindication
Imiyalo esetshenzisiwe ikhombisa imikhawulo enjalo ekusebenziseni umuthi:
- ukungabekezelelani komuntu ngamunye (hypersensitivity);
- ukwehluleka kwezinso okukhulu nesibindi;
- izifo ezinzima;
- thayipha i-1 isifo sikashukela;
- isifo sikashukela kanye ne-ketoacidosis;
- ukucaphuka
- ukukhulelwa
- i-pathologies engavusa izicubu ze-izicubu (ukushaqeka, ukuphefumula kanye nokwehluleka kwenhliziyo);
- i-lactic acidosis;
- ukunamathela ekudleni okhethekile, lapho kungadliwa ngaphezu kwe-1000 kcal ngosuku.
Ngokunakekela
- okunqunyelwe izingane ezivela eminyakeni eyi-10 (ngokuya izinkomba);
- isetshenziswa ekwelapheni asebekhulile (ngaphezulu kweminyaka engama-60-65 ubudala).
Ungayithatha kanjani iSiofor 850?
Isikhathi sokuphatha kanye nerejimeni yemithamo kunqunywa ngudokotela.
Ukwehla kwesisindo
Umthamo ojwayelekile wansuku zonke ekuqaleni kwezokwelapha (ukunciphisa umzimba) yithebhulethi le-1 izikhathi 1-2 ngosuku ngemuva noma ekudleni. Ngemuva kwamaviki awu-1.5-2, umthamo ungakhushulwa ube ngamathebhulethi angama-3-4 / ngosuku.
Kulokhu, ukugcwala kwe-glucose ku-plasma kanye nesimo sendlela yokugaya ukudla kufanele kugadwe.
Umthamo omkhulu ngamathebhulethi ayi-6 / ngosuku.
Umthamo ojwayelekile wansuku zonke ekuqaleni kwezokwelapha (ukunciphisa umzimba) yithebhulethi le-1 izikhathi 1-2 ngosuku ngemuva noma ekudleni.
Ukwelashwa kwesifo sikashukela
Into esebenzayo ingahlanganiswa ne-insulin ukukhulisa ukulawulwa kwe-glycemic.
Isilinganiso sokusebenzisa isilinganiso sokuqala ngu-0,5 g wesidakamizwa (i-1 ithebhulethi) izikhathi ezi-1-2 ngosuku.
Umthamo omkhulu yi-3 g yesidakamizwa.
Into esebenzayo ingahlanganiswa ne-insulin ukukhulisa ukulawulwa kwe-glycemic.
Imiphumela emibi
Amapheshana wesisu
- ukuqunjelwa;
- isifo sohudo
- ukulahleka kwesifiso sokudla;
- ukungakhululeki emgodini wesisu.
Lezi zimo zivame ukuvela ekuqaleni kokwelashwa bese zidlula zodwa.
Izitho zeHematopoietic
Uma usebenzisa umuthi, i-megaloblastic anemia can grow, kepha lokhu kuyaqabukela kakhulu.
Uma usebenzisa umuthi, i-megaloblastic anemia can grow, kepha lokhu kuyaqabukela kakhulu.
Isistimu yezinzwa ephakathi
- ikhanda (kanqabile);
- ukwephula ukunambitheka.
Engxenyeni yesibindi ne-biliary
- ukungasebenzi kahle kwesibindi okuhambisana nokwanda komsebenzi we-transaminase;
- ihepatitis.
Allergies
- I-edema kaQuincke;
- ukuluma nokuqhuma esikhunjeni.
Imiyalo ekhethekile
Uma usebenzisa umuthi, kunconywa ukulandela ukudla okhethekile.
Uma usebenzisa umuthi, kunconywa ukulandela ukudla okhethekile.
Ukuhambisana notshwala
Ukusetshenziswa kanyekanye kwezidakamizwa notshwala kungaholela emiphumeleni engalindeleki, ngakho-ke kungcono ukungazihlanganisi.
Umthelela ekhonweni lokulawula izindlela
Umuthi awuthinti imisebenzi ye-psychomotor.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Umuthi awunqunyelwe lapho uncelisa ingane ibele futhi izala ingane.
Ukuqokwa kukaSiofor ezinganeni ezingama-850
Ithuluzi livunyelwe ukusetshenziswa kusuka eminyakeni engu-10 ubudala.
Ithuluzi livunyelwe ukusetshenziswa kusuka eminyakeni engu-10 ubudala.
Sebenzisa ebudaleni
Kusetshenziswa ngokucophelela okukhulu ukwelapha abantu abaneminyaka engaphezu kwengu-65 ubudala, kuphela njengoba kuyalelwe ngudokotela nangokuqapha amazinga esibindi, izinso negazi lactate.
Umuthi akufanele ubekelwe abantu asebekhulile kanye neziguli uma benza umsebenzi onzima womzimba (ingozi enkulu yokuba ne-lactic acidosis).
Isicelo sokusebenza kokulimala kwezinso
Ukuphuza umuthi kuyinto engathandeki ezigulini ezihlushwa ama-pathologies ezinso ezinzima.
Sebenzisa umsebenzi wesibindi okhubazekile
Ayisetshenziselwa ukwehluleka kwesibindi okukhulu.
ISiofor 850 ayisetshenziselwa ukwehluleka kwesibindi okunamandla.
Ukweqisa
Ochwepheshe abenze izivivinyo zokwelashwa ngomuthi abaze baveze ukusabela okungekuhle ngenkathi kusetshenziswa imithamo efinyelela ku-85 g.
Kwezinye izimo, i-overdose ingahambisana nokukhula kwe-lactic acidosis.
Izimpawu eziphambili ze-pathology:
- ukuphazamiseka kokuphefumula;
- umuzwa wobuthakathaka;
- ukungakhululeki esiswini;
- isifo sohudo kanye nesicanucanu;
- ukuncipha kwengcindezi yegazi;
- uhlobo lwe-Reflex bradyarrhythmia.
Ngaphezu kwalokho, izisulu eziphuza imithamo ephezulu yezidakamizwa zingabuzwa ubuhlungu bemisipha nokuqaqanjelwa esikhaleni.
Ukwelapha kuyimpawu. Ohlukunyezwa ezimweni ezinjalo kufanele alaliswe esibhedlela ngokuphuthumayo. IHemodialysis ithathwa njengeyona ndlela ephumelelayo yokususa i-metformin ne-lactate emzimbeni.
Kwezinye izimo, i-overdose ingahambisana nokukhula kwe-lactic acidosis.
Ukuxhumana nezinye izidakamizwa
Inhlanganisela ehlanganisiwe
Ukulawulwa kwe-Intravascular izidakamizwa ezihlukile ne-iodine ezigulini zikashukela kungaholela ekwehlulekeni kanzima kwezinso.
Umenzeli we-hypoglycemic kumele akhanseliwe ezinsukwini ezi-2 ngaphambi kokwelashwa ngemithi enjalo.
Lokhu kudinga ukubhekwa ngokucophelela kokuhlakazwa kwento noshukela osegazini.
Akuhlanganisiwe ukuhlanganisa
Ingozi ye-lactic acidosis ikhuphuka kakhulu ngokudakwa okukhulu kakhulu nge-alcohol, ikakhulukazi ngokumelene nesizinda sokungondleki noma lapho kukhona ukwehluleka kwesibindi.
Ngakho-ke, ngalesi sikhathi, utshwala kufanele bushiywe, ngaphandle kwalokho ungahlangabezana nokuphulwa okunamandla kwesibindi nezinso.
Ingozi ye-lactic acidosis yanda kakhulu ekudakwiseni okuthe xaxa ngotshwala.
Inhlanganisela edinga ukuqashelwa
Ukusetshenziswa okuhlanganiswe kwalesi sidakamizwa noDanazole kungavusa umphumela we-hyperglycemic, ngakho-ke imithamo kufanele ikhethwe ngokuhlanganiswa okunjalo ngokunakekela okukhulu.
INifedipine neMorphine bakhulisa ukumuncwa kwe-metformin ku-plasma yegazi futhi yandisa isikhathi sokuphuma kwayo ngemuva kokuphathwa ngomlomo.
Izidakamizwa zeCationic zandisa ukugcwala kwe-plasma ye-metformin.
I-Cimetidine ivimbela ukuqedwa kwezidakamizwa, okwandisa ubungozi be-lactic acidosis.
I-Cimetidine ivimbela ukuqedwa kwezidakamizwa, okwandisa ubungozi be-lactic acidosis.
Ama-Analog
- Metfogamm;
- Metformin-Teva;
- I-Glucophage ende;
- Metformin Zentiva.
I-Analogue Glucofage ende.
Izimo zeholide Siofora 850 kusuka kumakhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela?
Ukuthenga amaphilisi udinga umuthi.
Intengo
Ukusuka kuma-ruble angama-255 wamathebulethi angama-60, enziwe ngegobolondo elimhlophe.
Izimo zokugcina zomuthi
Lapho ugcina umuthi, izinga lokushisa akufanele lidlule + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Umkhiqizi uSiofora 850
Berlin-Chemie (Germany).
Umkhiqizi uSiofora 850 "Berlin-Chemie" (Germany).
Ukubuyekezwa kwe-Siofor 850
Odokotela
Peter Klemazov (Therapist), oneminyaka engama-40, uVoronezh.
Le hypoglycemic ikhombisa imiphumela emihle ekwelashweni kwesifo sikashukela. Ngaphezu kwalokho, kuvame ukusetshenziselwa ukunciphisa umzimba. Ukungatholakali kokungaphenduki okubi kulo muthi kuyajabulisa, futhi intengo ebizayo yenza ihehe kakhulu.
Iziguli
UTatyana Vornova, oneminyaka engama-40, uTashkent.
Sekuphele iminyaka ngithatha lo muthi iminyaka eminingana, amaphilisi amabili ngosuku. Ushukela uhlala usezingeni elijwayelekile. Muva nje nginqume ukuqala ukuthatha ama-Strepsils futhi, njengoba umphimbo wami wawubuhlungu, kwadingeka ngiye kudokotela ukuze ngithole ngokuhambisana kwabo. Manje umphimbo awubuhlungu, futhi ushukela usejwayelekile! Kepha akukwenzeki ukuba ubone indlela yokuphila enempilo ngokuphelele.
Ukulahlekelwa isisindo
UVictoria Shaposhnikova, oneminyaka engama-36, uTver.
Kwangimangaza ukuthi umuthi uwashisa kanjani ngempumelelo amanye amakhilogremu. Ekuqaleni, akazange akholelwe ukuthandwa kwakhe, kodwa emavikini ama-2-3 ngemuva kokuqala kokwelashwa, wabona ukuthi isisindo siqala ukumuka kancane kancane. Kungakapheli izinyanga ezintathu, kungenzeka ukuthi ulahlekelwe ama-10 kg, futhi isisindo siyaqhubeka sincipha kancane, ngenkathi impilo nemizwelo kungahlupeki nakancane.
