Ukubonakala kwe-thrombosis yomthambo wegazi kungenye yezinqubo eziyingozi ezifaka isandla ekuthuthukisweni kwezifo ezinjengokwe-myocardial infarction kanye nesifo sohlangothi.
Izigidi zabantu ziyafa minyaka yonke ngenxa yezimo ezinjalo emhlabeni. Ezimweni eziningi, izidakamizwa ezivimbela ukwenzeka kwezigaba zegazi zingazonga.
I-ATX
I-Cardiomagnyl ifakiwe eqenjini lama-non-narcotic anti-inflammatory and antiplatelet agents. Igama elingelona elingafanele emhlabeni lo muthi yi: acetylsalicylic acid + magnesium hydroxide; ngesiLatini - Cardiomagnyl.
I-Cardiomagnyl ifakiwe eqenjini lama-non-narcotic anti-inflammatory and antiplatelet agents.
Ikhodi ye-ATX: B01AC30 (ama-antiplatelet agents).
Khipha amafomu nokwakheka
Wenziwe ngesimo samathebulethi ngesimo senhliziyo noma amaphilisi we-oblong enobungozi phakathi, ombozwe ngopende omhlophe obomvu.
Iphilisi ngalinye liqukethe:
- i-acetylsalicylic acid - 0,075 / 0,15 g;
- i-magnesium hydroxide - 0,0152 g / 0.03039 g.
Izici ezingeziwe zomuthi:
- isitashi sommbila - 0,0019 g;
- cellulose - 0,025 g;
- i-magnesium stearate - 305 mcg;
- polysaccharides - 0,004 g.
Kwenziwa ngesimo samathebulethi enziwe ngenhliziyo noma ngamaphilisi e-oblong anengozi phakathi.
Umuthi ufakelwe ku-vials ingilazi ansundu:
- Amaphilisi angama-30;
- Amaphilisi ayi-100.
Ibhodlela ngalinye ligcwele ebhokisini lekhadibhodi ngokulawulwa kokuvulwa kokuqala.
Indlela yokusebenza
Umphumela wemithi yalesi sidakamizwa ukuvimbela ukuvutshelwa kwe-cyclooxygenesis. Lokhu kudala ukuvimba ukukhiqizwa kabusha kwe-thromboxane kanye nokuvinjwa kokunamathela kweplatelet. Ngaphezu kwekhono lokuvimbela ukuhlangana, lo muthi ukwazi ukuba ne-analgesic emnene, i-anti-inflammatory kanye ne-antipyretic.
Umuthi uyakwazi ukuba ne-analgesic emnene, i-anti-inflammatory kanye ne-antipyretic.
Usawoti we-Magnesium okhona ekwakhekeni kwamathebulethi uvikela ulwelwesi lwe-mucous lwepheshana esiswini emiphumeleni emibi yama-salicylates.
I-Pharmacokinetics
Isakhi esisebenzayo somuthi simunzwa ngokuphelele yi-system gastrointestinal. Ukuqedwa kwesigamu sempilo yama-salicylates kuhlala imizuzu eyi-15. Ama-metabolites abo adalulwa kungakapheli amahora ama-3.
Yini edingekayo
Kunconywa ukuvikela ukuthuthukiswa kwe-thrombosis, imivimbo, ukufakwa kwe-myocardial eyinhloko noma ephindaphindekile nokwenzeka kwezimo ze-pathological ezifana:
- ukwehluleka kwenhliziyo;
- i-thromboembolism;
- ukuphazamiseka kokujikeleza ebuchosheni;
- i-angina pectoris engazinzi.
Ngaphezu kwalokho, lo makhambi unqunywe ngemuva kokuhlinzwa emikhunjini nasemithanjeni yemithambo yegazi.
Kunconywa ukuvikela ukuthuthukiswa kwe-thrombosis, imivimbo, infarction eyinhloko noma ephindaphindwe ye-myocardial.
Contraindication
Umuthi awunqunyelwe uma kukhona okuphula umthetho okufana:
- ukungabekezelelani komuntu ngamunye kuma-acetylsalicylic acid noma izingxenye ezisizayo zalo muthi;
- ukungabekezeleli amanye ama-NSAID;
- ukungasebenzi kahle kohlelo lokuhlangana kwegazi (ezimweni zokushoda kwe-Vitamin K, i-thrombocytopenia);
- izilonda zokulimala kwesisu ne-duodenum;
- ukwehluleka kwezinso noma kwesibindi;
- ukukhulelwa (1 no-3 trimesters).
Ayibekelwe izingane ezingaphansi kweminyaka engu-18. Ngaphezu kwalokho, azinqunyelwe kuma-regimens ayinkimbinkimbi yemiphumela yokwelapha ene-methotrexate.
Ungayithatha kanjani
Lo muthi kufanele ugwinywe wonke ngamanzi. Uma kunesidingo, singaphuka sibe izicucu noma sichotshozwe. Imithamo enconyiwe inqunywa yisimo sesiguli nokuba khona kwama-pathologies akhona.
I-Cardiomagnyl kufanele igwinywe lonke ngamanzi.
Njengendlela yokuvimbela ukubonakala kwezifo zemithambo, ukusetshenziswa kwalo muthi kwenziwa ngokwesikimu: umthamo wokuqala ukusetshenziswa okukodwa kwe-150 mg, bese kuthi-ke ngesikhathi se-75 mg. Uhlobo lonyango olufanayo lusetshenziselwa ukuvikela i-thrombosis ngemuva kokuhlinzwa okuhlaselayo.
Ekuseni noma kusihlwa
Kunconywa ukuba kuthathwe kusihlwa.
Ngaphambi noma ngemuva kokudla
Ukunciphisa umphumela omubi wama-salicylates kulwelwesi lwe-mucous lwepheshana emathunjini, lo muthi unconywa ukuba uphuzwe kuphela ngemuva kokudla.
Isikhathi esingakanani ukuthatha
Isikhathi sokuphatha sincike esimweni sesiguli kanye nokuba khona kwezifo ezikhona.
Kunganconywa kuphela ngudokotela lapho kunezimpawu ezibonisa ubungozi be-pelo pathologies, noma ngezifo ze-vascular.
Ukuthatha umuthi wesifo sikashukela
Abantu abanesifo sikashukela banamaplathile anamathela. Ngakho-ke, odokotela bangancoma ukuthatha le mishanguzo ukunciphisa igazi futhi inciphise ukubonakala kwayo. Imiphumela yokwelapha enjalo inciphisa ingozi yokwakheka kwezifo zemithambo yegazi nesistimu yenhliziyo.
Imiphumela emibi
Lo muthi unohlu oluncane lwemiphumela engathandeki, ngoba inokwakheka okulula. Ngaphandle kwalokhu, ama-salicylates angadala ukulimala okukhulu emzimbeni.
Ngenkathi uthatha lesi sidakamizwa, ukubonakaliswa ngesimo sokuqhuma kwesikhumba, ukulunywa, i-bronchospasm kanye ne-edema kaQuincke kungenzeka.
Ngakho-ke, lapho kuvela izimpawu ezinjalo, kufanele uyeke ukusebenzisa umuthi futhi ufune izeluleko zikadokotela wakho.
Amapheshana wesisu
Ukusabela esiswini:
- isicanucanu
- ukuhlanza
- i-anorexia;
- izinhlungu zesisu;
- isifo sohudo
Kwesinye isikhathi kuyenzeka ukuthi kube nokwakheka kokuqina okulimazayo nokulimala ezindongeni zesisu kube nezimpawu zokuphuma kwegazi.
Izitho zeHematopoietic
Ukuthatha lesi sidakamizwa kungadala ukwehla kwamazinga e-platelet (i-thrombocytopenia) ne-hemoglobin egazini (anemia).
Ukuthatha i-Cardiomagnyl kungavusa ukwehla kwamazinga e-platelet and hemoglobin egazini.
Kwesinye isikhathi ukusetshenziswa kwama-salicylates kunganciphisa okuqukethwe kwama-neutrophils egazini (neutropenia), izinga leukocytes (agranulocytosis) noma kwandise inani lama-eosinophils (eosinophilia).
Allergies
Ngenkathi uthatha lesi sidakamizwa, ukubonakaliswa ngesimo sokuqhuma kwesikhumba, ukulunywa, i-bronchospasm kanye ne-edema kaQuincke kungenzeka.
Isistimu yezinzwa ephakathi
Ukuthatha i-salicylates kungaholela kusiyezi, ikhanda, ukubuyela emuva kwe-optic nerve, i-tinnitus ne-aseptic meningitis.
Imiyalo ekhethekile
Ukudlula imithamo edukisiwe yalesi sidakamizwa kungadala ukopha kwangaphakathi.
Uma isiguli sine-hypotension ye-arterial, ukusetshenziswa komuthi kungaholela ekukhuleni kwe-hemorrhagic stroke.
Lo muthi kufanele ulahlwe ezinsukwini ezingama-5-7 ngaphambi kokuhlinzwa.
Ngaphezu kwalokho, ama-salicylates asiza ukunciphisa i-uric acid excretion, ngakho-ke ukuthatha la maphilisi kungadala ukuhlaselwa yi-gout.
Ukuhambisana notshwala
Lo muthi awunconywa ukuhlanganiswa notshwala. Uma kwenziwa ndawonye, kuthuthukisa isenzo somunye nomunye.
Umthelela ekhonweni lokulawula izindlela
Akunalo ulwazi ngomphumela walesi sidakamizwa ekuqalisweni kwemisebenzi edinga ukunakwa okwengeziwe kokunakwa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukuthatha lo muthi kuphambaniswe ku-trimesters ye-1 ne-3 yokukhulelwa. Ezigabeni zokuqala, le nto ingavusa ukungasebenzi kahle kwengane, futhi kuthi lapho sekwedlule isikhathi ibangele ukuphazamiseka emsebenzini. Kwi-trimester yesi-2, unikezwa ngokuqapha (kuphela ngokuhlolwa okuqinile kwesilinganiso sobungozi bomama kanye ne-fetus).
Ama-metabolites alesi sidakamizwa adlulela kalula kubisi lwebele. Ngakho-ke, isikhathi sokwelashwa kusuka ekunceliseni ibele kufanele kushiywe.
Ukuqokwa kwe-Cardiomagnyl ezinganeni
Ngokwemiyalelo yokusetshenziswa, lo muthi awubekelwe abantu abangaphansi kweminyaka engu-18 ubudala. Uma udokotela eyichaza ingane ebusheni, isibopho sokukhetha umthamo nendlela yokusebenzisa umuthi ilele nodokotela.
Sebenzisa ebudaleni
Kubantu asebekhulile, lo muthi unconywa njenge-prophylactic ngokumelene nokubonakala kwe:
- i-infarction ye-myocardial eyingozi kakhulu;
- i-arterial hypertension;
- isifo sohlangothi;
- ingozi ye-cerebrovascular;
- embolism wamaphaphu wesistimu yokujikeleza kwegazi.
Isicelo sokusebenza kokulimala kwezinso
Umuthi awuvunyelwe ukusetshenziswa ekwehlulekeni kwezinso. Sebenzisa ngokuqapha ezigulini ezinesifo sezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Umuthi uphambaniswe nokuhluleka kwesibindi. Kunqunyelwe ngokuqapha ezigulini ezinezifo zesibindi.
Kunqunyelwe ngokuqapha ezigulini ezinezifo zesibindi.
Ukweqisa
Ukubonakaliswa komtholampilo ubuthi ngenxa yokusetshenziswa okungalawulwa kwalesi sidakamizwa kumithamo ephezulu kungenzeka ngesimo se:
- isicanucanu
- ukuhlanza
- tinnitus;
- ukubanjwa
- izimo zokushisa;
- ukwehlisa umfutho wegazi;
- ukwazi ukungasebenzi kahle (kuze kufike ekuqaleni komqondo);
- inhliziyo noma ukwehluleka ukuphefumula.
Ukwelashwa kwalezi zimpawu kuya ngesimo sesiguli.
Ubuthi obunzima, ukulaliswa esibhedlela esiphuthumayo kuyadingeka.
Kungakhathalekile ukuthi bunjani ubulukhuni, ukuhanjiswa kwesisu kanye nokusetshenziswa kwamalungiselelo we-sorbent (ngokwesibonelo, namalahle ocushiwe) kuyadingeka.
Ukuxhumana nezinye izidakamizwa
Ukuhlangana kwezidakamizwa kwalesi sidakamizwa nge-methotrexate akukuthinti kabi ukukhiqizwa kwegazi.
Ukuphathwa kanyekanye kwalo muthi kungakhuthaza imiphumela yezindlela zemithamo efana:
- IHeparin;
- I-Ticlopidine;
- Ibuprofen;
- I-Digoxin;
- I-Valproic acid;
- I-Benzbromarone.
Ngaphezu kwalokho, ukuhambisana nezidakamizwa ezithile kuthuthukisa umphumela wazo. lokhu:
- okususwayo kwe-salicylic acid, ama-NSAID;
- ama-hypoglycemic agents (ama-sulfonylurea kanye ne-insulin).
- ama-thrombolytic, anticoagulant kanye ne-antiplatelet agents.
Ama-Analog
Azikho i-analogues eziqondile, kepha umuthi ungashintshwa namanxusa nge-salicylic acid derivatives. Kodwa noma imiphi leyo mithi izokwehluka uma kungekho i-magnesium hydroxide - isakhi esivikela izindonga zesisu emiphumeleni eyingozi yama-salicylates.
Phakathi kokufakwa esikhundleni kwama-antiplatelet agents kufaka:
- Aspirin Cardio;
- Acecardol;
- Aspicore
- I-Thrombotic ACC;
- Phasostable;
- I-Trombital Forte;
- I-Thrombital nabanye.
Phakathi kokufakwa esikhundleni kwama-antiplatelet agents kufaka nomuthi i-Thrombo AS
Izimo Zamaholide Wekhemisi Mildronata
Ikhishwa ngemithi kadokotela.
Malini
Ungasithenga lesi sidakamizwa kunoma iyiphi ikhemisi. Izindleko zincike kwinani lamathebulethi kuphakeji nomthamo wento esebenzayo. Intengo emaphakathi iyahluka ngaphakathi:
- 75 mg, iphakethe No. 30 - 110-160 ruble;
- 75 mg, iphakheji No. 100 - 170-280 ruble;
- I-150 mg, iphakheji engu-30 - ama-ruble ayi-100-180;
- I-150 mg, iphakheji engu-100 - ama-ruble angama-180-300.
Izimo zokugcina zomuthi i-Mildronate
Kufanele igcinwe endaweni emnyama neyomile; lokushisa - hhayi ngaphezulu kuka + 25 ° С. Gwema kude nezingane.
Impilo yeshelf umuthi
Iminyaka emi-4 kusukela ngosuku lokukhiqizwa.
Ukubuyekezwa okumaphakathi
Odokotela baphawula imiphumela ehlukahlukene yemithi nemiphumela engathandeki ngemuva kokuyiphuza.
Ukubuyekezwa kodokotela
Manin Yu.K., udokotela wezokwelapha, uKursk
Ukulungiselela okusebenzayo futhi okungabizi kakhulu kwe-acetylsalicylic acid. Isilinganiselo se-Optimum kanye nokulula kokudosa. Bengilokhu ngiyincoma ezigulini zami iminyaka eminingi. Ukuvimbela isifo senhliziyo, amaphilisi kufanele athathwe 1 nge-0,075 g kusihlwa ngemuva kokudla. Lapho isetshenziswa esiswini esingenalutho, iba nomphumela omubi kulwelwesi lwe-mucous lwesisu ne-duodenum; kuholela ekhipha ukopha emgodini wokugaya ukudla.
I-Timoshenko A.V., isazi sezinhliziyo, i-Oryol
Imithamo mincane futhi isebenza ngempumelelo ekuvimbeleni isifo senhliziyo. Kepha awukwazi ukuthi lo muthi unazo lezo zakhiwo ezinganazo.
Zakhamizi zakithi! Lo muthi awuphathi i-arrhythmia, umfutho wegazi ophakeme, noma yisiphi esinye isimo se-pathological. Inhloso yaleli thuluzi ukunciphisa amathuba okuthuthukisa i-atherothrombosis. Ngakho-ke, ungalindeli noma yikuphi ukuthuthuka kwezempilo ngemuva kokuthatha i-Aspirin noma izidakamizwa eziqukethe i-acetylsalicylic acid.
I-Kartashkova E.A., isazi sezinhliziyo, uKrasnodar
Umuthi osebenzayo ekutholeni i-enteric. Ngincoma kubantu abangaphezu kweminyaka engama-50. Iziguli zibekezelela kahle. Kumkhuba wami, akukho miphumela emibi eye yabonwa. Ukuqokwa kungokwezinkomba nangaphansi kokuhlolwa ngudokotela.
