I-Aspirin Cardio isetshenziselwa ukuvikela i-thrombosis, ukushaya kwenhliziyo, kanye nokubuyisa umzimba ngemuva kokuhlinzwa enhliziyweni noma emithanjeni yegazi. Amaphilisi asiza ukubuyisa ukujikeleza kwegazi ebuchosheni.
Ath
Ukuhlukaniswa kwe-Anatomical-Therapeutic-Chemical (ATX) - B01AC06.
NgesiLatini, igama lesi sidakamizwa lizwakala kanjena - u-Aspirin Cardio.
I-Aspirin Cardio isetshenziselwa ukuvikela i-thrombosis, ukushaya kwenhliziyo, kanye nokubuyisa umzimba ngemuva kokuhlinzwa enhliziyweni noma emithanjeni yegazi.
Khipha amafomu nokwakheka
I-Aspirin C yithebhulethi emhlophe eyindilinga efakwe i-enteric. Umuthi utholakala ngevolumu engu-100 noma engama-300 mg. I-carton iqukethe ama-2 noma 4 amanxeba, ngokuya ngenani lamathebulethi (10 noma 14).
Okuqukethwe kwithebhulethi kufaka phakathi into esebenzayo - i-acetylsalicylic acid. 1 pc akhawunti ama-300 noma ama-100 mg wengxenye. Abangenayo bafaka:
- i-cellulose powder - 10 noma 30 mg;
- isitashi sommbila - 10 noma 30 mg.
Ukwakheka kwegobolondo kufaka phakathi:
- i-Copolymer ye-methaconic acid ne-ethacrylate 1: 1 (Eudragit L30D) - 7.857 noma 27, 709 mg; polysorbate 80 - 0.186 noma 0.514 mg;
- i-sodium lauryl sulfate - 0,057 noma u-0.157 mg;
- i-talc - i-8.1 noma i-22.38 mg;
- triethyl citrate - 0,8 noma 2.24 mg.
Isenzo se-Pharmacological
Umuthi ubhekisela kuma-painkiller kanye nemithi elwa nokuvuvukala (okungeyona i-steroidal) nemithi ethinta izicubu zomzimba (i-antiplatelet agent).
Isenzo se-Pharmacological - anti-aggregation. Izici ze-Aspirin Cardio zihambisana nethonya lezinto ezisebenzayo emzimbeni. Njengomphumela wokuvimba i-prostaglandinsynthetase, i-enzyme ebandakanyeka ku-prostaglandin biosynthesis, ukukhiqizwa kwama-hormone okuvuvukala kuvinjelwe. Ngakho-ke, umuthi uyakwazi ukuba nemiphumela ye-analgesic, antipyretic ne-anti-inflammatory.
I-Aspirin Cardio isetshenziselwa ukuvikela i-thrombosis, ukushaya kwenhliziyo, kanye nokubuyisa umzimba ngemuva kokuhlinzwa enhliziyweni noma emithanjeni yegazi.
Ukuvela kwe-thrombosis kuncishisiwe ngenxa yokuthi ingxenye esebenzayo ibambezela ukunamathela kanye nezakhiwo ezinamathela zamaplatelet. I-Aspirin ithinta ikhono le-plasma yegazi ku-fibrinolysis futhi inciphisa inani lezinto ezihlanganayo. Ibuyisela umsebenzi weplatelet.
Lapho uthatha umuthi, ukwanda kwamaseli wezinzwa kuya ezintweni ezicasulayo kuyancipha.
Lokhu kungenxa yokwehla kwenani labalamuli abangavuvukalanga abathwali bokucasulwa. Uyakwazi ukukhiqiza umphumela we-antipyretic.
I-Pharmacokinetics
Ngemuva kokuthi i-acetylsalicylic acid ingene emzimbeni, umuthi udonswa emzimbeni wokugaya ukudla. Ngesikhathi sokufakwa, isitho esisebenzayo singena kwi-metabolite - i-salicylic acid. Umuthi ulolongwa esibindini ngama-enzyme anjenge-phenyl salicylate, glucuronide salicylate ne-salicyluric acid, atholakala izicubu eziningi nomchamo.
Ngenxa yomsebenzi ophansi wokwakheka kwama-enzyme ku-serum yegazi yabesifazane, inqubo ye-metabolic yehliswa kancane. I-ASA itholakala ku-plasma yegazi imizuzu eyi-10-20 ngemuva kokusetshenziswa, i-salicylic acid - ngemuva kwemizuzu engama-30-60.
Ama-ASA avikelwe igobolondo elimelana ne-acid, ngakho-ke into ayikhululwa esiswini, kodwa endaweni ye-alkali ye-duodenum. Ukufakwa kwe-Acid kwehlisa amahora angama-3-6, ngokungafani namathebulethi angenawo umjovo we-enteric.
Ama-acid aboshelwe kumaprotheni e-plasma futhi asakazeka ngokushesha emzimbeni wonke womuntu. I-salicylic acid iyakwazi ukungena ku-placenta futhi icishwe ubisi lwebele. Umuthi ukhishwa emzimbeni ngenkathi kusebenza izinso. Ngokusebenza okujwayelekile komzimba, lesi sidakamizwa sikhishwa kungakapheli izinsuku ezingama-1-2 kusetshenziswa umuthi owodwa.
Ngokusebenza okujwayelekile komzimba, lesi sidakamizwa sikhishwa kungakapheli izinsuku ezingama-1-2 kusetshenziswa umuthi owodwa.
Okusizayo
Umuthi unqunywe emacaleni alandelayo:
- Izindlela zokuthibela zokuqothuka kwe-myocardial infarction ebusweni bezimpawu zobungozi. Lokhu kufaka phakathi: isifo sikashukela, umfutho wegazi ophakeme, ukukhuluphala (ukukhuluphala), ukuguga, ukusetshenziswa njalo kwezinto ze-nicotinic.
- I-Angina pectoris, kufaka phakathi amafomu azinzile futhi angazinzi.
- I-Hypovolemia.
- I-vascular thrombosis.
- Umfutho wegazi ophezulu we-Arterial.
- Ukuvimbela Unhlangothi
- Ukuphazamiseka kweHematologic.
- Ukwephulwa kokujikeleza kwe-cerebral, ukulimala kwengqondo kwe-ischemic.
- Ingozi yokuqhekeka kwegazi okujulile ne-pulmonary embolism, kubandakanya namagatsha ayo.
- Ukuvimbela i-thromboembolism ngemuva kokuhlinzwa emikhunjini.
Umuthi futhi unqunyelwe izingozi ze-cerebrovascular, ukulimala kobuchopho be-ischemic.
Contraindication
Ukusetshenziswa kwesidakamizwa akunconywa ezimweni ezilandelayo:
- hypersensitivity kuzakhi zomuthi;
- isifuba somoya
- ukwephulwa komgudu wokugaya ukudla (izilonda, ukopha kwesisu);
- iminyaka yezingane;
- isikhathi sokuncelisa;
- ukukhulelwa
- I-hepatic, renal kanye nokwehluleka kwenhliziyo.
Ngokunakekela
Lapho uphuzwa kanye nezidakamizwa ezimbalwa, ngaphambi kokuhlinzwa (umuthi ungadala ukulahleka kwegazi), ku-3rd trimester yokukhulelwa.
Ukuqapha kuyadingeka ukuthi uthathe amaphilisi ngaphambi kokuhlinzwa (umuthi ungadala ukulahleka kwegazi).
Ungayithatha kanjani
Thatha umuthi njengoba unconywe udokotela noma ngokuya ngemiyalo. Kusetshenziswa ngaphakathi, kugezwe phansi ngenani elikhulu loketshezi. Uma kufiswa, ithebhulethi ingachotshozwa futhi ichithwe emanzini. Noma kunconywa ukuthi uthathe umuthi ngaphandle kokugaya, uphelele.
Isikhathi sini
Amaphilisi anconyelwa ngaphambi kokudla.
Isikhathi esingakanani singakwenza
Inkambo yokwelashwa inqunywe ngudokotela. Ngokusetshenziswa isikhathi eside, ukudakwa komzimba kungenzeka.
Ngoshukela
Kunconywa ukuphuza izidakamizwa nsuku zonke.
Imiphumela emibi
Umthamo obaliwe ngokungalungile wesidakamizwa ungaholela emiphumeleni emibi evela kuzo zonke izinhlelo zomzimba.
Umthamo obaliwe ngokungalungile wesidakamizwa ungaholela emiphumeleni emibi evela kuzo zonke izinhlelo zomzimba.
Amapheshana wesisu
Isicanucanu, ukushaya kwenhliziyo, ukugabha, ukusika ubuhlungu besisu. Akuvamile, ukwakheka kwezilonda esiswini.
Izitho zeHematopoietic
Ukwanda kwegazi esikhathini se-postoperative, ukwakhiwa kwamanxeba okulimaza, ukuncipha kwegazi ekhaleni, ipheshana lomchamo, izinsini ezopha igazi. Kunobufakazi bokukhubazeka kwe-cerebral hemorrhages, ukopha kwesisu.
Isistimu yezinzwa ephakathi
Isiyezi, ikhanda, i-tinnitus, ukulahleka kwesikhashana kwezindlebe.
Kusuka ohlelweni lomchamo
Umsebenzi wezinso ongasebenzi kahle, ukuhluleka kwe-renal akuvamile.
Allergies
Ukushintshwa kwesikhumba (ukuqubuka, ukulunywa, isifo se-Addison), ukuvuvukala kwe-mucosa yamakhala, i-rhinitis, ukungezwani komzimba kohlelo lokuphefumula (i-asthma, ukushaqeka kwe-anaphylactic).
Imiyalo ekhethekile
Umuthi kufanele usetshenziswe njengoba kuyalelwe udokotela. Imiphumela emibi nokwanda ngokweqile kuyingozi kakhulu kubantu asebekhulile.
Ukuhambisana notshwala
Iziphuzo ze-Acid nezotshwala azihambelani. Ukusetshenziswa ngasikhathi sinye kungadala imiphumela emibi (kwenyusa ingcindezi, kuthuthukisa izifo zenhliziyo), kunciphisa izakhiwo zokupholisa zomuthi.
Umthelela ekhonweni lokulawula izindlela
Akuthinti amandla okushayela izimoto.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Umuthi uthinta kabi inkambo yokukhulelwa nokukhula kwesibeletho.
Ukuthatha umuthi ngomuthi ongaphezu kwama-300 mg / ngosuku ku-1st trimester yokukhulelwa kuthuthukisa ukukhula kwe-pathologies ku-fetus. Kwi-trimester yesi-3, ukuthatha amaphilisi kungadala ukuvimbela kokubeletha, kunyuswe ukulahleka kwegazi kumama nakibelethayo. Ingane ingaba nokuzwa kokukhubazeka kokubeletha kanye nokufa ngokushesha uma umuthi udakiwe ngaphambi kokubeletha. Ngakho-ke, ukuthatha umuthi ngalesi sikhathi ku-contraindified.
Umuthi uthinta kabi inkambo yokukhulelwa nokukhula kwesibeletho.
Kwi-trimester yesi-2, isiguli singathatha i-Aspirin ngemuva kokuhlola ubungozi empilweni kamama no-fetus uchwepheshe. Umthamo akufanele wedlule i-150 mg / ngosuku.
Ngokuthatha isikhashana umuthi, umuthi wokuncelisa awukwazi ukumiswa, ngoba inani elilinganiselwe lezinto zokwelapha lingena ebisini, elingadali miphumela emibi enganeni. Ngokusebenzisa isikhathi eside kwamathebulethi ngesikhathi sokuqunjelwa, ukuncelisa kufanele kumiswe kuze kube yilapho izinto sezikhishwe ngokuphelele emzimbeni kamama.
Ukunquma i-Aspirin Cardio ezinganeni
Umuthi awunconyelwe ukuthi usetshenziswe yizingane ezingaphansi kweminyaka engu-15 ubudala nezifo zokuphefumula ezinamandla ezibangelwa ukutheleleka. Lokhu kuhlotshaniswa nengozi yeReye syndrome.
Uma kungekho sifo, udokotela ubeka umthamo osuselwa esilinganisweni somzimba sengane nokuxilongwa isifo sayo. Umuthi wokusebenzisa owodwa uvame ukusetshenziswa.
Ukuze uqinise uhlelo lwenhliziyo, kunconywa ukuphuza iTaurur.
Umuthi awunconyelwe ukuthi usetshenziswe yizingane ezingaphansi kweminyaka engu-15 ubudala nezifo zokuphefumula ezinamandla ezibangelwa ukutheleleka.
Sebenzisa ebudaleni
Ukwemukelwa kufanele kwenziwe ngokuhambisana nezincomo zikadokotela uma kungekho okuphikiswa. Ngokuvamile esetshenziswa eminyakeni yobudala ekuvimbeleni isifo senhliziyo.
Ukweqisa
Ngoshevu omnene noma olinganiselayo, kuvela izimpawu ezilandelayo:
- Isiyezi
- ukukhuphuka kokujuluka;
- isicanucanu, ukuhlanza
- ukudideka.
Uma kutholakala izimpawu, bonana nodokotela. Ngaphambi kokunikeza ukunakekelwa kwezokwelapha, ukusetshenziswa okuphindaphindiwe kwekhabhoni esebenzayo, kunconywa ukubuyiselwa kwemali esele.
Uma kutholakala izimpawu, bonana nodokotela. Ngaphambi kokunikeza ukunakekelwa kwezokwelapha, ukusetshenziswa okuphindaphindiwe kwekhabhoni esebenzayo, kunconywa ukubuyiselwa kwemali esele.
Ezimweni ezinzima ze-overdose eziphawuliwe:
- ukwanda kokushisa komzimba;
- ukwehluleka ukuphefumula;
- ukwephula kwenhliziyo, izinso, isibindi;
- i-tinnitus, isithulu;
- Ukopha kwe-GI.
Ukwelashwa kudinga ukulaliswa esibhedlela isiguli ngokushesha.
Ukuxhumana nezinye izidakamizwa
Ngokusebenzisa kanyekanye, izenzo zomuthi olandelayo ziyathuthukiswa:
- I-Methotrexate.
- IHeparin kanye ne-anticoagulants engaqondile.
- I-Digoxin.
- Ama-Hypoglycemic agents.
- I-Valproic acid.
- Ama-NSAIDs.
- I-Ethanol (kufaka phakathi uphuzo oludakayo).
Ngokusetshenziswa ngasikhathi sinye, umphumela weMethotrexate uyathuthukiswa.
Yehlisa umphumela wemithi yemithi elandelayo:
- Ama-diuretics.
- Ama-inhibitors e-ACE.
- Ngomphumela we-uricosuric.
Ama-Analog
Ukufana kwezidakamizwa kufaka phakathi: I-Cardiask, i-Upsarin UPSA, iTerrombo ACC, iCardiomagnyl. Uma kungenzeka, i-Aspirin kufanele isetshenziswe uma ichazwe udokotela.
Uyini umehluko phakathi kwe-Aspirin ne-Aspirin Cardio
- ukwakheka kwezidakamizwa;
- ukugoqa i-Aspirin Cardio nge-membrane ekhethekile ukuvikela ulwelwesi lwepheshana esiswini ekulimaleni;
- umthamo
- inani.
Imibandela yekhefu lekhemisi
Ngaphandle kwemithi kadokotela.
Intengo ye-Aspirin Cardio
E-Russia, izindleko zomuthi ziyehluka kusuka kuma-ruble angama-90 kuye kwangama-276.
Izimo zokugcina zomuthi i-Aspirin Cardio
Gcina endaweni yokushisa engeqi i-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emi-5
Ukubuyekezwa ku-Aspirin Cardio
UValera, oneminyaka engama-49 ubudala, uVolgograd: "Udokotela uzonikeza izithambisi zegazi lapho kunengozi yokuqhekeka kwegazi. Isimo sesingcono kepha kwesinye isikhathi sibanga ukushayeka kwenhliziyo."
USvetlana, 33, Mozhaysk: "Kanye nemiphumela emihle, imiphumela emibi nayo iyabonakala. Angikwazanga ukuthatha lesi sidakamizwa: izinhlungu zesisu, isiyezi esijwayelekile. Amaphilisi abhalwe phansi ayeshibhile, futhi aqeda ngokushesha imithambo ye-varicose."
U-Oleg, oneminyaka engama-44 ubudala, uNorilsk: "Amaphilisi abekiwe njengezinkinga zemithambo yemilenze. Ngasiqeda lesi sifo. Akunamiphumela emibi."
