I-Diabeteson MV yikhambi lesifo sikashukela sohlobo 2. Into esebenzayo yi-gliclazide. Ivuselela amaseli we-pancreatic beta ukukhiqiza i-insulin ethe xaxa, ehlisa ushukela wegazi. Kubhekiswa kokutholakala kwe-sulfonylurea. I-MB ngamathebulethi wokukhishwa modified. IGliclazide ayikhishwa masinyane kubo, kepha ngokulingana esikhathini esingamahora angama-24. Lokhu kunikeza usizo ekwelapheni isifo sikashukela. Kodwa-ke, isifo sikashukela asithathwa njengesinqumo sokuqala sohlobo 2 sikashukela. Kunconywa ukuba kunqunywe kuphela ngemuva kwe-metformin. Funda izinkomba ezinemininingwane yokusetshenziswa, ama-contraindication, imithamo, izinzuzo kanye nokubi kwe-Diabeteson MV esihlokweni. Thola ukuthi lo muthi ungafakwa ini esikhundleni ukuze kungalimali emiphumeleni yayo emibi.
Imephu yezidakamizwa
| Umkhiqizi | I-Les Laboratoires Serviceier Industrie (France) / Serdix LLC (Russia) |
| Ikhodi ye-PBX | A10BB09 |
| Iqembu lezemithi | I-Oral hypoglycemic drug, i-sulfonylurea derivatives yesizukulwane sesibili |
| Into esebenzayo | I-Gliclazide |
| Khipha ifomu | Amacwecwe Okukhishwa Okuguquliwe, 60 mg. |
| Ukupakisha | Kubhebhezelwa amaphilisi ayi-15 ebhulashini, amabhliki ama-2 anemiyalo yokusetshenziswa kwezokwelapha efakwe ekhadini lekhadibhodi. |
| Isenzo se-Pharmacological | Izibhebhe zokunciphisa ushukela wegazi eqenjini le-sulfonylurea. Ukugqugquzela ukukhiqizwa kwe-insulin ngamaseli e-beta weziqithi ze-pancreatic zeLangerhans. Umuthi awugcini nje ngokuthuthukisa isigaba sesibili se-insulin secretion, kodwa futhi ubuyisela izinga lokuphakama kwawo kokuqala lapho kuphendula ukudonswa kweglucose. Futhi kunciphisa ubungozi be-thrombosis encane yegazi. Ama-molecule we-Diabeteson MV abonisa izakhiwo ze-antioxidant. |
| I-Pharmacokinetics | Ukuthatha umuthi kanye ngosuku kuqinisekisa ukugcinwa kwe-gliclazide ephumelelayo kwe-plasma yegazi amahora angaphezu kwama-24. Ichithwa ikakhulukazi yizinso ngendlela yama-metabolites, ngaphansi kwe-1% - nomchamo ungashintshiwe. Kudala, azikho izinguquko ezibalulekile kumapharamitha we-pharmacokinetic. Ukudla akuphazamisi isilinganiso noma isilinganiso sokufakwa kwe-gliclazide. |
| Izinkomba zokusetshenziswa | Thayipha isifo sikashukela sesi-2, uma ukudla nokuvivinya umzimba kungasizi ngokwanele. Ukuvimbela izinkinga zesifo sikashukela i-mellitus: ukunciphisa ubungozi be-microvascular (nephropathy, retinopathy) nezinkinga ezi-macrovascular (infarction myocardial, stroke) ngokuqapha ushukela wegazi kakhulu. |
| Umthamo | Umthamo wokuqala wabantu abadala, kufaka phakathi asebekhulile, ngu-30 mg ngosuku (1/2 ithebhulethi). Iyakhula ingabi kanye kanye emavikini angama-2, uma ushukela ungehliswa ngokwanele. Imithamo efanelekile ikhethwe ngokuqondile, ngokwezinkomba zeglue egazini kanye ne-glycated hemoglobin HbA1C. Umthamo omkhulu yi-120 mg ngosuku. Ungahlanganiswa neminye imithi yesifo sikashukela. Ithebhulethi elilodwa lesidakamizwa i-Diabeteson 80 mg ingashintshwa yithebhulethi eyi-1/2 ngokukhishwa okuguqulwayo kweDiabeteson MB 60 mg. Lapho udlulisela iziguli kusuka kumuthi i-Diabeteson 80 mg ku-Diabeteson MB, kunconywa ukukala ushukela nge-glucometer kaningana ngosuku, uyiqaphe ngokucophelela. Bheka futhi, "Amanani Ushukela Wegazi Wabantu Abanempilo Nesifo Sikashukela." |
| Imiphumela emibi | Umphumela oyingozi oyingozi ushukela wegazi ophansi, i-hypoglycemia. Izimpawu zalo: ikhanda, ukukhathala, ukungabekezeleleki, amaphupho amabi, ukuzindla. Ezimweni ezinzima, isiguli singalahlekelwa ukwazi. Funda isihloko esithi "Hypoglycemia - Izimpawu, Ukwelashwa Nokuvimbela" ngemininingwane engaphezulu. I-Diabeteson MV ibangela i-hypoglycemia enzima kaningi kunezinye izidakamizwa - ezitholakala sulfonylurea. Eminye imiphumela emibi Ubuhlungu besisu, isicanucanu, ukugabha, ukuhudula, ukuqunjelwa, ukugabha, ukulunywa, umsebenzi owengeziwe wama-enzyme wesibindi (AST, ALT, alkaline phosphatase). Ekuqaleni kokuthatha i-Diabeteson, kungahle kube nokulimazeka okubonakalayo kwesikhashana - ngenxa yokuthi ushukela wegazi usheshe wehle. I-Hepatitis ne-jaundice nazo kungenzeka, kodwa akuvamile. Izinguquko ezingezinhle ekwakhekeni kwegazi azivamile. |
| Contraindication | I-Diabeteson MV nezinye izinto eziphuma ku-sulfonylurea zinohlu olubanzi lwe-contraindication:
Nikeza ngokuqapha:
|
| Ukukhulelwa nokuncelisa ibele | I-Diabeteson MV namanye amaphilisi kashukela akufanele aphuzwe ngesikhathi sokukhulelwa. Uma udinga ukwehlisa ushukela wegazi - kwenze lokhu ngokudla nemijovo ye-insulin. Nakani kakhulu ukulawula isifo sikashukela ngesikhathi sokukhulelwa ukuze kungabikho ukuzalwa okunzima nokungalungiseki kwengane. Akwaziwa ukuthi umuthi udlulela obisini lwebele. Ngakho-ke, ngesikhathi sokuqunjelwa ayinqunyelwe. |
| Ukusebenzelana kwezidakamizwa | Izidakamizwa eziningi zikhulisa ubungozi be-hypoglycemia uma zithathwe noDiabetes. Lokhu kufanele kubhekwe ngudokotela lapho ebeka ukwelashwa okuhlanganisiwe kwesifo sikashukela nge-acarbose, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, ama-agonists we-GLP-1, kanye ne-insulin. Umphumela we-Diabeteson MV ukhuliswa yizidakamizwa zehypertension - i-beta-blockers kanye ne-ACE inhibitors, kanye ne-fluconazole, i-histamine H2-receptor blockers, i-MAO inhibitors, i-sulfonamides, i-clarithromycin. Ezinye izidakamizwa zingahle zibe buthaka umphumela we-gliclazide. Funda imiyalo esemthethweni ukuze uyisebenzise ngemininingwane eminingi. Tshela udokotela wakho ngayo yonke imishanguzo, izithasiselo zokudla, namakhambi owaphuzayo ngaphambi kokuthatha amaphilisi akho kashukela. Qondisisa ukuthi ungazilawula kanjani ushukela wegazi ngokuzimela. Yazi okufanele ukwenze uma kukhuphuka noma okuphambene nalokho kuphansi kakhulu. |
| Ukweqisa | Ngokweqile kwe-sulfonylurea derivatives, i-hypoglycemia ingaqala ukukhula. Ushukela wegazi uzokwehla ngokujwayelekile, futhi lokhu kuyingozi. I-hypoglycemia emnene ingamiswa yodwa, futhi ezimweni ezinzima, ukunakekelwa kwezokwelapha okuphuthumayo kuyadingeka. |
| Khipha ifomu | Amacwecwe wokukhishwa aguquliwe amhlophe, i-oval, i-biconvex, ene-notch futhi aqoshwe "DIA" "60" kuzinhlangothi zombili. |
| Imigomo nemibandela yesitoreji | Gcina ungafinyeleleki ezinganeni, imibandela ekhethekile ayidingeki. Impilo yeshelf iyiminyaka emi-2. Ungasebenzisi ngemuva kosuku lokuphelelwa isikhathi okukhonjiswe kwiphakheji. |
| Ukwakheka | Into esebenzayo yi-gliclazide, 60 mg kwithebhulethi eyodwa. I-Excipients - i-lactose monohydrate, i-maltodextrin, i-hypromellose, i-magnesium stearate, i-anhydrous colloidal silicon dioxide. |
Ukusetshenziswa kwesidakamizwa Diabeteson
Umuthi obizwa ngokuthi yi-Diabeteson amaphilisi ajwayelekile kanye nokukhishwa okuguquliwe (i-MV) unqunyelwe iziguli ezinesifo sikashukela sohlobo 2, okuthi ekudleni nasekuzivivinyeni kusilawule kahle lesi sifo. Into esebenzayo yesidakamizwa yi-gliclazide. Kungokweqembu elithathwe ku-sulfonylurea. IGliclazide ivuselela amaseli we-pancreatic beta ukuze akhiqize futhi akhulule i-insulin eyengeziwe egazini, i-hormone eyehlisa ushukela.
Kunconywa okokuqala ukunquma iziguli ezinesifo sikashukela ezi-2 hhayi i-Diabeteson, kepha umuthi weMetformin - uSiofor, iGlucofage noma amalungiselelo eGliformin. Imithamo ye-metformin ikhula kancane kancane isuka ku-500-850 iye ku-2000-3000 mg ngosuku. Futhi kuphela uma lokhu kulungisa kwehlisa ushukela ngokungafanele, okutholwa sulfonylurea kuyengezelelwa kukho.
I-Gliclazide kumathebhulethi wokukhishwa okuqhubekayo isebenza ngokungafani amahora angama-24. Kuze kube manje, izindinganiso zokwelashwa kwesifo sikashukela zincoma ukuthi odokotela banikeze i-Diabeteson MV ezigulini zabo ezinesifo sikashukela sohlobo 2, esikhundleni se-sulfonylureas yesizukulwane esedlule. Isibonelo, bheka isihloko esithi "Imiphumela yocwaningo lwe-DYNASTY (" I-Diabeteson MV: uhlelo lokuhlola phakathi kweziguli ezinesifo sikashukela sohlobo lwe-2 ngaphansi kwezimo ezijwayelekile zokuziphatha ")" kumagazini "Izinkinga ze-Endocrinology" No. 5/2012, umbhali uM. V. Shestakova, O K. Vikulova nabanye.
I-Diabeteson MV yehlisa ushukela wegazi kakhulu. Iziguli ezinjengale ukuthi kulula ukuyithatha kanye ngosuku. Isebenza ngokuphephile kunezidakamizwa ezindala - izinto ezisuselwa ku-sulfonylurea. Noma kunjalo, inomphumela olimazayo, ngenxa yalokho okungcono ukuthi abanesifo sikashukela bangayidli. Funda ngezansi ukuthi yikuphi ukulimala kweDiabetes, okuhlanganisa zonke izinzuzo zako. Iwebhusayithi yeDiabetes-Med.Com ikhuthaza ukwelashwa okusebenzayo kwesifo sikashukela sohlobo 2 ngaphandle kwamaphilisi ayingozi.
- Ukwelashwa kwesifo sikashukela sohlobo 2: inqubo yesinyathelo-ngesinyathelo - ngaphandle kokubulawa yindlala, izidakamizwa eziyingozi nemijovo ye-insulin
- Amatafula weSiofor ne-Glucofage - metformin
- Ungakufunda kanjani ukujabulela imfundo yomzimba
Izinzuzo kanye nokubi
Ukwelashwa kwesifo sikashukela sohlobo 2 ngosizo lomuthi i-Diabeteson MV kunikeza imiphumela emihle esikhathini esifushane:
- ezigulini, ushukela wegazi wehla kakhulu;
- ubungozi be-hypoglycemia abudlulwa ngaphezu kwe-7%, okuyinto ephansi kakhulu kunakwezinye izinto ezisuselwa ku-sulfonylurea;
- kungcono ukuthatha umuthi kanye ngosuku, ukuze iziguli zingayeki ukwelashwa;
- ngenkathi uthatha i-gliclazide kumathebulethi wokukhishwa okuqhubekayo, isisindo somzimba sesiguli sanda kancane.
I-Diabeteson MB isiphenduke uhlobo oludumile lomuthi 2 wesifo sikashukela ngoba inenzuzo kodokotela futhi ilungele iziguli. Kulula kaningi ukuthi ama-endocrinologists anikeze amaphilisi kunokukhuthaza abanesifo sikashukela ukuba balandele ukudla nokuzivocavoca. Umuthi usheshe wehlise ushukela futhi ubekezeleleke kahle. Azikho ngaphezu kwe-1% leziguli ezikhononda ngemiphumela emibi, futhi bonke abanye banelisekile.
Ububi besidakamizwa Diabeteson MV:
- Kusheshisa ukufa kwamangqamuzana e-pancreatic beta, ngenxa yokuthi lesi sifo sidlulela kuhlobo olubi lwesifo sikashukela. Lokhu kuvame ukwenzeka phakathi kweminyaka emibili nengu-8.
- Kubantu abanciphile futhi abanciphile, isifo sikashukela esinzima esincike ku-insulin sibangela ngokushesha okukhulu - kungakapheli iminyaka eyi-2-3.
- Akususi imbangela yesifo sikashukela sohlobo 2 - umuzwa onciphile wamaseli ukuya ku-insulin. Lokhu kuphazamiseka kwe-metabolic kubizwa ngokuthi yi-insulin ukumelana. Ukuthatha isifo sikashukela kungakuqinisa.
- Yehlisa ushukela wegazi, kepha ayinciphisi ukufa kwabantu. Lokhu kuqinisekiswe yimiphumela yocwaningo olukhulu lwamanye amazwe nge-ADVANCE.
- Umuthi lo ungadala i-hypoglycemia. Kuliqiniso, amathuba ayo angaphansi kokuthi uma kuthathwe ezinye izinto ze-sulfonylurea. Kodwa-ke, isifo sikashukela sohlobo 2 singalawulwa kalula ngaphandle kwengozi ye-hypoglycemia.
Ochwepheshe kusukela ngabo-1970 bazi ukuthi ukuphuma kwe-sulfonylurea kubangela ukuguquka kwesifo sikashukela sohlobo 2 kusifo sohlobo olu-1 sikashukela esinamandla kakhulu. Kodwa-ke, le mithi isaqhubeka ichazwe. Isizathu ukuthi basusa umthwalo kodokotela. Uma kungekho amaphilisi anciphisa ushukela, khona-ke odokotela bekuzodingeka babhale phansi uhlobo lokudla, ukuzivocavoca, kanye ne-insulin regimen kulowo nalowo onesifo sikashukela. Lokhu kungumsebenzi onzima futhi ongabongi. Iziguli ziziphatha njengeqhawe likaPushkin: "Akunzima ukungikhohlisa, ngiyajabula ukuzikhohlisa." Bazimisele ukuphuza umuthi, kepha abathandi ukulandela indlela odla ngayo, ukuzivocavoca umzimba, kanye nokunye kakhulu ukujova i-insulin.
Umphumela owonakalisayo we-Diabeteson kumaseli we-beta we-pancreas ngokoqobo awukhathaleli ama-endocrinologists neziguli zawo. Akukho ukushicilelwa kumaphephabhuku ezokwelapha mayelana nale nkinga. Isizathu ukuthi iningi leziguli ezinesifo sikashukela sohlobo 2 azinaso isikhathi sokuphila ngaphambi kokuba zikhiqize isifo sikashukela esincike ku-insulin. Isistimu yenhliziyo yabo isixhumanisi esibuthakathaka ukwedlula i-pancreas. Ngakho-ke, babulawa ukuhlaselwa yinhliziyo noma unhlangothi. Ukwelashwa kwesifo sikashukela sohlobo 2 esisuselwa ekudleni okune-carbohydrate ngasikhathi sinye kusenza ushukela, umfutho wegazi, imiphumela yokuhlolwa kwegazi kwe-cholesterol nezinye izici zobungozi bezinhliziyo.
Imiphumela yolingo yomtholampilo
Isivivinyo esikhulu semitholampilo somuthi i-Diabeteson MV kwaba isifundo i-ADVANCE: Isifo sikashukela nesifo se-VAscular -
i-preterax ne-Diamicron MR Ukulawulwa kokuLawulwa. Yasungulwa ngo-2001, kwathi imiphumela yashicilelwa ngonyaka we-2007-2008. I-Diamicron MR - IGliclazide kumathebhulethi wokukhishwa modified athengiswa ngaphansi kwaleli gama emazweni akhuluma isiNgisi. Lokhu kuyefana nomuthi i-Diabeteson MV. I-Preterax umuthi wokuhlanganisa wehypertension, izithako ezisebenzayo zazo ezinge-indapamide ne-perindopril. Emazweni akhuluma isiRussia, ithengiswa ngaphansi kwegama elithi Noliprel. Ucwaningo lolu lubandakanye iziguli eziyi-11,140 ezinesifo sikashukela sohlobo 2 kanye nomfutho wegazi ophakeme. Babukwe odokotela ezikhungweni zezokwelapha ezingama-215 emazweni angama-20.
I-Diabeteson MV yehlisa ushukela wegazi, kepha ayinciphisi ukushona kweziguli ezinesifo sikashukela sohlobo 2.
Ngokwemiphumela yocwaningo, kuvela ukuthi amaphilisi okucindezela ezigulini ezinesifo sikashukela sohlobo 2 anciphisa imvamisa yezinkinga zenhliziyo ngama-14%, izinkinga zezinso - ngo-21%, ukufa kwabantu - ngo-14%. Ngasikhathi sinye, iDiabeteson MV yehlisa ushukela wegazi, yehlisa imvamisa ye-nephropathy yesifo sikashukela ngo-21%, kepha ayithinti ukufa kwabantu. Umthombo wolimi lwaseRussia - isihloko esithi "Ukwelashwa okuqondiswa kweziguli ezinesifo sikashukela sohlobo lwe-2: imiphumela yocwaningo lwe-ADVANCE" ephephabhukwini "I-Systemic hypertension" No. 3/2008, umlobi u-Yu. Karpov. Umthombo woqobo - “I-ADVANCE Collaborative Group. Ukulawulwa kweglucose enzulu nemiphumela yemithambo ezigulini ezinesifo sikashukela sohlobo 2 ”kuyi-New England Journal of Medicine, 2008, No. 358, 2560-2572.
Iziguli ezinesifo sikashukela sohlobo 2 zinikezwa amaphilisi anciphisa ushukela kanye nemijovo ye-insulin uma ukudla nokuzivocavoca kunganikeli imiphumela emihle. Eqinisweni, iziguli zimane nje azifuni ukulandela ukudla okune-calorie ephansi nokuzivocavoca. Bancamela ukuthatha umuthi. Ngokomthetho kukholelwa ukuthi ezinye izindlela zokwelapha ezisebenzayo, ngaphandle kwezidakamizwa kanye nokufakwa imijovo emikhulu ye-insulin, azikho. Ngakho-ke, odokotela bayaqhubeka nokusebenzisa amaphilisi anciphisa ushukela angehli ukufa kwabantu. KuDiabetes-Med.Com ungathola ukuthi kulula kanjani ukulawula isifo sikashukela esingu-2 ngaphandle kokudla “okulambile” kanye nokujova kwe-insulin. Asikho isidingo sokuphuza umuthi olimazayo, ngoba ezinye izindlela zokwelapha zisiza kahle.
- Ukwelashwa kwe-hypertension kuziguli ezinesifo sikashukela sohlobo 1 nohlobo 2
- Amacimbi we-Pressure Noliprel - I-Perindopril + Indapamide
Amathebulethi wokukhishwa alungisiwe
I-Diabeteson MV - amaphilisi wokukhishwa modified.Umuthi osebenzayo - i-gliclazide - ukhishwa kubo kancane kancane, hhayi ngokushesha. Ngenxa yalokhu, ukuhlanganiswa okufana kwe-gliclazide egazini kugcinwa amahora angama-24. Thatha lo muthi kanye ngosuku. Njengomthetho, kunqunywa ekuseni. I-Common Diabeteson (ngaphandle kwe-CF) umuthi osekhulile. Ithebhulethi yakhe ichithwa ngokuphelele emgodini wesisu ngemuva kwamahora angama-2-3. Yonke i-gliclazide equkethe ingena ngokushesha egazini. I-Diabeteson MV yehlisa ushukela kahle, kanye namathebulethi ajwayelekile ngokunamandla, futhi umphumela wabo uphela ngokushesha.
Amathebulethi wokukhishwa an modified anezinzuzo ezinkulu ezidakamizweni ezindala. Into esemqoka ukuthi baphephe. I-Diabeteson MV ibangela i-hypoglycemia (ishukela elehlisiwe) izikhathi ezimbalwa ngaphansi kwe-Diabeteson ejwayelekile kanye nezinye izinto ezisuselwa kushukela. Ngokusho kocwaningo, ubungozi be-hypoglycemia abudluli kuma-7%, futhi imvamisa udlula ngaphandle kwezimpawu. Ngokuphikisana nesizinda sokuthatha isizukulwane esisha somuthi, i-hypoglycemia enobunzima obungazi kahle emzimbeni ayiveli. Lo muthi ubekezelelwa kahle. Imiphumela emibi iphawulwa hhayi ngaphezulu kwe-1% yeziguli.
| Amathebulethi wokukhishwa alungisiwe | Amathebhulethi enza ngokushesha | |
|---|---|---|
| Zingaki ngosuku okufanele uzithathe | Kanye ngosuku | Izikhathi ezi-1-2 ngosuku |
| Isilinganiso se-Hypoglycemia | Kuphansi kakhulu | Phezulu |
| Ukuncipha kweseli kwe-pancreatic beta | Kancane | Ngokushesha |
| Isisindo sokuthola isisindo | Akubalulekile | Phezulu |
Ezindabeni kumaphephabhuku ezokwelapha, baphawula ukuthi i-molecule ye-Diabeteson MV iyi-antioxidant ngenxa yesakhiwo sayo esiyingqayizivele. Kepha lokhu akunanzuzo esebenzayo, akukuthinti ukusebenza kahle kokulashwa kwesifo sikashukela. Kuyaziwa ukuthi iDiabeteson MV inciphisa ukwakheka kwezigaba zegazi egazini. Lokhu kunganciphisa ubungozi bokushaywa unhlangothi. Kepha akukho lapho kufakazelwe ukuthi umuthi unikeza umphumela onjalo. Ukushiyeka kwekhambi lesifo sikashukela - okuphuma ku-sulfonylurea - bekubalwe ngenhla. Ku-Diabeteson MV, lokhu kusilela kukhulunywa kancane kunasemithini endala. Inomphumela omnene kakhudlwana kumaseli we-beta wamanyikwe. Thayipha i-insulin yesifo sikashukela ayiqali ngokushesha.
Ungawuthatha kanjani lo muthi
Amacwecwe i-Diabeteson MV kufanele athathwe ngaphezu kokudla nokuzivocavoca, hhayi esikhundleni salokho. Yize abanenkinga yesifo sikashukela abaningi bengazinaki izincomo zokwelashwa zokushintsha kwendlela enempilo. Udokotela ubeka umthamo womuthi nsuku zonke, kuye ngokuthi ushukela wegazi ophakeme uphezulu kangakanani. Umthamo obekiwe awunakudlulwa noma wehliswe ngokunqunyelwe. Uma uthatha isifo sikashukela ngaphezu kokunqunyelwe, khona-ke i-hypoglycemia ingenzeka - ushukela ophansi kakhulu. Izimpawu zayo ukungabekezeleleki, ukuvevezela izandla, ukujuluka, indlala. Ezimweni ezimbi kakhulu, ukulahleka kwengqondo nokufa kungenzeka. Bheka futhi "I-Hypoglycemia - izimpawu, ukwelashwa, ukuvimbela."
I-Diabeteson MV ithathwa kanye ngosuku, imvamisa ngesidlo sasekuseni. Ithebhulethi engabhalwanga engu-60 mg ingahlukaniswa izingxenye ezimbili ukuthola umthamo wama-30 mg. Kodwa-ke, ayinakwekwa noma ichotshozwe. Lapho uthatha umuthi, uwaphuze ngamanzi. Iwebhusayithi yeDiabetes-Med.Com ikhuthaza ukwelashwa okusebenzayo kwesifo sikashukela sohlobo 2. Bayakuvumela ukuthi ulahle iDiabeteson, ukuze ungazivezi emiphumeleni yayo emibi. Kodwa-ke, uma uphuza amaphilisi, uwasebenzise nsuku zonke ngaphandle kwezikhala. Ngaphandle kwalokho ushukela uzokhuphuka kakhulu.
Kanye nokuthatha isifo sikashukela, ukubekezelela utshwala kungaqala ukwanda. Izimpawu ezingenzeka wukukhanda ikhanda, ukuphefumula, ukuqaqamba kwamalunga, ubuhlungu besisu, isicanucanu nokuhlanza.
Ama-Derivatives we-sulfonylureas, kufaka phakathi iDiabeteson MV, akuzona izidakamizwa zokukhetha zokuqala ezinesifo sikashukela sohlobo 2. Ngokusemthethweni, kunconywa ukuthi iziguli zinqunywe kuqala kuwo wonke amaphilisi we-metformin (Siofor, Glucofage). Kancane kancane, umthamo wabo ukhuphuka ufike ku-2000-3000 mg ngosuku. Futhi kuphela uma lokhu kungenele, engeza i-Diabeteson MV eningi. Odokotela abanquma isifo sikashukela esikhundleni se-metformin benza okungalungile. Zombili lezi zidakamizwa zingahlanganiswa, futhi lokhu kunikeza imiphumela emihle. Okungcono futhi, shintshela ohlelweni lokwelapha isifo sikashukela sohlobo 2 ngokwenqaba amaphilisi ayingozi.
I-Diabeteson MV ingahlanganiswa namanye amaphilisi kashukela, ngaphezu kwe-sulfonylureas ne-ironides (meglitinides). Bheka futhi "Umuthi 2 wesifo sikashukela: i-athikili enemininingwane." Uma uDiabeteson enganciphisi ushukela wegazi, khona-ke udinga ukudlulisela isiguli kumijovo ye-insulin. Kulesi simo, awekho amanye amaphilisi azosiza. Qala ngokujova i-insulin, ungachithi isikhathi, ngaphandle kwalokho kuzovela izinkinga ezinzima zesifo sikashukela.
Ama-dravatives e-sulfonylureas enza isikhumba sizwakale kakhulu emisebeni ye-ultraviolet. Ingozi eyandayo yokushiswa yilanga. Kunconywa ukusebenzisa ama-sunscreens, futhi kungcono ukuthi ungashisi ilanga. Cabanga ngengozi ye-hypoglycemia engabangelwa yi-Diabeteson. Lapho ushayela noma wenza umsebenzi oyingozi, vivinya ushukela wakho nge-glucometer njalo ngemizuzu engama-30-60.
Ubani ongamlingani
Isifo sikashukela i-MV akufanele sithathwe kunoma ngubani, ngoba ezinye izindlela zokwelapha isifo sikashukela sohlobo 2 zisiza kahle futhi azibangeli imiphumela emibi. Imibiko esemthethweni ibhalwe ngezansi. Futhi thola ukuthi yiziphi izigaba zeziguli okufanele zinikezwe lo muthi ngokuqapha.
Ngesikhathi sokukhulelwa nokuncelisa, noma iliphi iphilisi lokunciphisa ushukela liyaphulwa. I-Diabeteson MV ayibekelwe izingane nentsha, ngoba ukusebenza kwayo nokuphepha kwalo mkhakha weziguli akukasungulwa. Ungawuphuthi lo muthi uma ngaphambili ungawukelani nawo noma kwamanye ama-sulfonylurea. Lo muthi akufanele uthathwe yiziguli ezinesifo sikashukela sohlobo 1, futhi uma unesifo esingazinzile sohlobo 2 sikashukela, iziqephu ezivame kakhulu ze-hypoglycemia.
Okususwa sulfonylureas ngeke kuthathwe ngabantu abanezifo ezinzima zesibindi nezinso. Uma unesifo sikashukela se-nephropathy, khuluma nodokotela wakho. Ngokunokwenzeka, uzokweluleka ukubuyisela amanye amaphilisi ngemijovo ye-insulin. Kubantu asebekhulile, iDiabeteson MV ilungele ngokusemthethweni uma isibindi sabo nezinso zisebenza kahle. Ngokungemthetho, kuvusa ukuguqulwa kwesifo sikashukela sohlobo 2 kube uhlobo olukhulu lokuncika lwe-insulin. Ngakho-ke, abanesifo sikashukela abafuna ukuhlala isikhathi eside ngaphandle kwezinkinga, kungcono ukungayithathi.
Kukuziphi izimo lapho Diabeteson MV enqunywe ngokuqapha:
- I-hypothyroidism - umsebenzi ongenamandla we-gland yegland kanye nokushoda kwama-hormone ayo egazini;
- ukuntuleka kwama-hormone akhiqizwa indlala ye-adrenal kanye ne-pituitary gland;
- ukungondleki okungajwayelekile;
- utshwala.
Isifo sikashukela
Umuthi wokuqala i-Diabeteson MV ukhiqizwa yinkampani yezemithi i-Laboratory Serviceier (France). Kusukela ngo-Okthoba 2005, wayeka ukuletha umuthi wesizukulwane esedlule e-Russia - amaphilisi uDiabeteson 80 mg obambe ngokushesha. Manje ungathenga kuphela i-Diabeteson MV yasekuqaleni - amaphilisi wokukhishwa aguquliwe. Leli fomu lemithamo linezinzuzo ezinkulu, futhi umenzi wanquma ukugxila kukho. Kodwa-ke, i-gliclazide kumathebulethi wokukhishwa okusheshayo asathengiswa. Lezi yizifanekiselo zeDiabetes, ezikhiqizwa abanye abenzi.
| Igama lezidakamizwa | Inkampani yezokukhiqiza | Izwe |
|---|---|---|
| UGlidiab MV | I-Akrikhin | IRussia |
| Diabetesalong | Synthesis OJSC | IRussia |
| IGliclazide MV | I-LLC Ozone | IRussia |
| I-Diabefarm MV | Ukukhiqizwa kwePhemisi | IRussia |
| Igama lezidakamizwa | Inkampani yezokukhiqiza | Izwe |
|---|---|---|
| UGlidiab | I-Akrikhin | IRussia |
| I-Glyclazide-AKOS | Synthesis OJSC | IRussia |
| UDiabinax | Impilo kaShreya | India |
| I-Diabefarm | Ukukhiqizwa kwePhemisi | IRussia |
Ukulungiselela okunesithako esisebenzayo se-gliclazide kumathebulethi wokukhishwa okusheshayo manje sekuphele. Kungcono ukusebenzisa i-Diabeteson MV noma ama-analogues ayo esikhundleni salokho. Okungcono kakhulu ukwelashwa kwesifo sikashukela sohlobo 2 olususelwa ekudleni okune-carbohydrate ephansi kakhulu. Uzokwazi ukugcina ushukela wegazi ojwayelekile, futhi ngeke udinge ukuthatha izidakamizwa eziyingozi.
I-Diabeteson noma iManinil - okungcono
Umthombo walesi sigaba kwaba yisihloko esithi "Izingozi zokufa okujwayelekile nokwenhliziyo, kanye nokulimazeka kwengqondo nokushayisana kwengqondo kweziguli ezinesifo sikashukela sohlobo lwe-2 kuye ngohlobo lokuqala ukwelashwa kwe-hypoglycemic" ephephabhukwini "Isifo sikashukela" No. 4/2009. Ababhali - I.V. IMisnikova, A.V. Dreval, Yu.A. Kovaleva.
Izindlela ezahlukahlukene zokwelapha isifo sikashukela sohlobo lwe-2 zinemiphumela ehlukile engcupheni yokuhlaselwa yisifo senhliziyo, ukushaywa unhlangothi kanye nokushona kweziguli ngokuphelele. Ababhali balesi sihloko bahlaziya imininingwane equkethwe kwirejista ye-mellitus yesifo sikashukela saseMoscow, okuyingxenye yeRegional State of Diabetes Mellitus weRussian Federation. Bahlola idatha yabantu abatholakala benesifo sikashukela sohlobo 2 ngo-2004. Baqhathanisa umphumela we-sulfonylureas ne-metformin uma belashwa iminyaka engu-5.
Kwavela ukuthi izidakamizwa - izinto ezithathwe yi-sulfonylurea - ziyingozi kunokuba zisize. Indlela abenze ngayo ngokuqhathanisa ne-metformin:
- ubungozi bokushona okujwayelekile nokwenhliziyo - kabili;
- ingozi yokuhlaselwa yisifo senhliziyo - ikhuphuke ngezikhathi ezingama-4.6;
- ubungozi bokushaywa unhlangothi bukhuphuke kathathu.
Ngasikhathi sinye, i-glibenclamide (Maninil) yayilimaza kakhulu kune-gliclazide (Diabeteson). Kuliqiniso, i-athikili leyo ayizange iveze ukuthi yiziphi izinhlobo zeManilil neDiabeteson ezisetshenzisiwe - amaphilisi okubambezeleka noma okwejwayelekile. Kungakujabulisa ukuqhathanisa imininingwane neziguli ezinesifo sikashukela sohlobo 2 ezinqunywe ngokushesha ukwelashwa kwe-insulin esikhundleni samaphilisi. Kodwa-ke, lokhu akwenziwe, ngoba iziguli ezinjalo bezinganele. Iningi leziguli zenqaba ngokwezifiso ukufaka umjovo i-insulin, ngakho-ke sanikezwa amaphilisi.
Imibuzo Ebuzwa Njalo nezimpendulo
I-Diabeteson ilawule kahle uhlobo lwami lwesifo sikashukela iminyaka emi-6, futhi manje isyekile ukusiza. Wandisa umthamo wakhe waba ngu-120 mg ngosuku, kepha ushukela wegazi ususezingeni eliphakeme, i-10-12 mmol / l. Kungani umuthi ulahlekelwe ukusebenza kwawo? Ngabe selashwa kanjani manje?
I-Diabetesone itholakala sulfonylurea. Lawa maphilisi anciphisa ushukela wegazi, kodwa futhi abe nomphumela olimazayo. Kancane kancane babhubhisa amaseli we-pancreatic beta. Ngemuva kweminyaka engu-2-9 yokuzithatha ezigulini, umzimba uqala ukungabi nalutho ngokuphelele lwe-insulin. Umuthi ulahlekelwe ukusebenza kwawo ngoba amaseli akho e-beta “asephelile.” Lokhu kungenzeka. Ngabe selashwa kanjani manje? Isidingo sokujova i-insulin, akukho okukhethwa kukho. Ngoba unesifo sikashukela sohlobo 2 saphenduka uhlobo olukhulu lwesifo sikashukela. Khansela i-Diabeteson, shintshela ekudleni okuphansi kwe-carbohydrate bese ufaka i-insulin engaphezulu ukugcina ushukela ojwayelekile.
Umuntu osekhulile ubephethwe isifo sikashukela sohlobo 2 iminyaka engu-8. Ushukela wegazi 15-17 mmol / l, izinkinga zithuthukisiwe. Wathatha i-manin, manje esedluliselwe kuDiabeteson - kwaba nhlanga zimuka nomoya. Kufanele ngiqale ukuthatha i-amaryl?
Isimo esifanayo nesombhali wombuzo owedlule. Ngenxa yeminyaka eminingi yokwelashwa okungalungile, uhlobo 2 lwesifo sikashukela seluphenduke uhlobo olunzima lwesifo sikashukela. Awekho amaphilisi azonikeza noma yimuphi umphumela. Landela uhlelo lokwelapha isifo sikashukela sohlobo loku-1, qala ukujova i-insulin. Ekusebenziseni, ngokuvamile akunakwenzeka ukuthola ukwelashwa okufanele kwabashukela asebekhulile. Uma isiguli sibonisa ukukhohlwa nokuqina - shiya konke njengoba sinjalo bese ulinda ngomoya ophansi.
Ngokwesifo sikashukela sohlobo 2, udokotela ungimisele i-850 mg ngosuku kuSiofor kimi. Ngemuva kwezinyanga eziyi-1.5, wathuthela eDiabeteson, ngoba ushukela awuzange wehle nhlobo. Kepha umuthi omusha nawo awusetshenziswa kangako. Ngabe kufanelekile ukuya eGlibomet?
Uma uDiabeteson engehli ushukela, khona-ke i-Glibomet ngeke ibe yiluphi usizo. Ufuna ukwehlisa ushukela - qala ngokujova i-insulin. Ngokwesimo sikashukela osezingeni eliphezulu, alikho elinye ikhambi elisebenzayo elisunguliwe. Okokuqala, shintshela ekudleni okuphansi kwe-carbohydrate bese uyeka ukuthatha izidakamizwa eziyingozi. Kodwa-ke, uma usunomlando omude wesifo sikashukela sohlobo 2 futhi uphathwe ngendlela engafanele eminyakeni edlule, kuzodingeka futhi futhi ufake umjovo we-insulin. Ngoba ama-pancreas ancishisiwe futhi awakwazi ukubhekana ngaphandle kokuxhaswa. Ukudla okune-carb ephansi kuzokwehlisa ushukela wakho, kepha hhayi ngokwesilinganiso. Ngakho-ke, ukuthi izinkinga azikhuli, ushukela kufanele ungabi ngaphezu kwama-5.5-6.0 mmol / l amahora angama-1-2 ngemuva kokudla nokusa ekuseni ngesisu esingenalutho. Faka insulin kancane ukuze ufeze le nhloso. I-Glibomet isidakamizwa esihlanganisiwe. Kubandakanya i-glibenclamide, enomphumela ofanayo oyingozi njengoDiabetes. Ungawusebenzisi lo muthi. Ungathatha i- "pure" metformin - uSiofor noma uGlyukofazh. Kodwa awekho amaphilisi angafaka imijovo ye-insulin.
Kungenzeka yini ukuthi isifo sikashukela sohlobo 2 sithathe i-Diabeteson ne-tsoxin yokunciphisa umzimba ngasikhathi sinye?
Isifo sikashukela ne-saxin sisebenzelana kanjani - akukho datha. Kodwa-ke, i-Diabeteson ivusa ukukhiqizwa kwe-insulin ngamanyikwe. I-insulin iguqula i-glucose ibe ngamafutha futhi ivimbele ukwehla kwezicubu ze-adipose. Lapho uthola i-insulin egazini ngokwengeziwe, kuba nzima ngokwengeziwe ukwehlisa umzimba. Ngakho-ke, isifo sikashukela ne-tsoxin sinomphumela ophambene. I-Reduxin ibanga imiphumela emibi futhi umlutha usheshe ube kuyo. Funda isihloko esithi “Unganciphisa kanjani isisindo sikashukela sohlobo 2.” Yekani ukuthatha isifo sikashukela nesosxin. Shintshela ekudleni okuphansi kwe-carbohydrate. Ibuyisela ushukela, umfutho wegazi, i-cholesterol egazini, futhi amakhilogremu angeziwe nawo ayahamba.
Sekuphele iminyaka emi-2 ngithatha i-Diabeteson MV, ushukela osheshayo ugcina cishe i-5.5-6.0 mmol / l. Kodwa-ke, umuzwa ovuthayo ezinyaweni usanda kuqala futhi umbono uyawa. Kungani izinkinga zikashukela zanda yize ushukela ujwayelekile?
Kuyadingeka ukulawula ushukela amahora angama-1-2 ngemuva kokudla futhi ekuseni ngesisu esingenalutho. Amazinga kashukela ngaphambi kwasemini nakusihlwa awabalulekile. Ezigulini eziningi ezinesifo sikashukela sohlobo 2, ushukela wokuzila uyinto evamile. Kodwa-ke, iba nezinkinga lapho kukhuphuka ushukela wegazi amahora amaningi isikhathi ngasinye ngemuva kokudla. Ukulinganisa ushukela esiswini esingenalutho futhi ungayihloleli amahora ama-1-2 ngemuva kokudla ukuzikhohlisa. Kufanele uyikhokhele ngokwakhiwa kwezinkinga zesifo sikashukela. Bheka futhi - amazinga kashukela egazi kubantu abaphilile neziguli ezinesifo sikashukela.
Udokotela unqume uDiabeteson ushukela omningi, kanye nokudla okune-kilojoule kanye nokungadli okumnandi. Kepha akazange asho ukuthi kungakanani ukukhawulela umthamo wekhalori. Uma ngidla amakhalori angama-2 000 ngosuku, ingabe lokho kuvamile? Noma ingabe udinga okuncane?
Ukudla okulambile kusiza ngokweqiniso ukulawula ushukela wegazi, kodwa ekusebenzeni, cha. Ngoba zonke iziguli ziyahlukana naye. Akunasidingo sokuhlala uphila ngendlala! Funda futhi ulandele uhlelo lokwelapha isifo sikashukela sohlobo 2. Shintshela ekudleni okuphansi kwe-carbohydrate - kuyinhliziyo, kuyamnandi futhi kunciphisa ushukela kahle. Yekani ukuthatha amaphilisi ayingozi. Uma kunesidingo, faka i-insulin engaphezulu. Uma isifo sikashukela sakho singasebenzi, ungagcina ushukela ojwayelekile ngaphandle kokujova i-insulin.
Ngithatha iDiabeteson neMetformin ukukhokhela iT2DM yami. Ushukela wegazi ubamba 8-11 mmol / L. Isazi se-endocrinologist sithi lokhu kungumphumela omuhle, futhi izinkinga zami zempilo zihlobene nobudala. Kepha ngibona sengathi izinkinga zesifo sikashukela ziyaqala. Yikuphi ukwelashwa okusebenzayo kakhulu ongakuncomela?
Ushukela wegazi ojwayelekile - njengabantu abanempilo, hhayi ngaphezulu kuka-5.5 mmol / l ngemuva kwamahora 1 no-2 ngemuva kokudla. Kunoma yiliphi inani eliphakeme, izinkinga zikashukela ziyavela. Ukwehlisa ushukela wakho kube okwejwayelekile futhi kugcinwe uzinzile, cwaninga bese ulandela uhlelo lokuelapha isifo sikashukela sohlobo 2. Isixhumanisi saso sinikezwe empendulweni yombuzo owedlule.
Udokotela wayala ukuthatha i-Diabeteson MV ebusuku, ukuze kube noshukela ojwayelekile ekuseni esiswini esingenalutho. Kepha imiyalo ithi udinga ukuthatha la mapilisi ukuze uthole ibhulakufesi. Ngubani okufanele ngithembe - imiyalo noma umbono kadokotela?
Udinga ukwenza okuthile ebusuku ukuze ushukela ujwayelekile ngakusasa ekuseni. Udokotela wakho uqinisile ngalokhu :). Kepha ukuthatha i-Diabeteson kungumbono omubi, ngoba lawa amaphilisi ayingozi. Yini ongayifaka esikhundleni sayo kuchazwe kabanzi ngenhla. Bheka futhi "Indlela yokujwayeza ushukela ekuseni." Uma udinga ukufaka i-insulin ende isikhathi eside ebusuku - kwenze, ungabi lazy.
Isiguli esinesifo sikashukela sohlobo 2 nesipiliyoni seminyaka engu-9, iminyaka engama-73. Ushukela ukhuphukela ku-15-17 mmol / l, futhi i-manin ayilihlisi. Waqala ukwehlisa umzimba ngokweqile. Ngabe kufanele ngishintshele ku-Diabeteson?
Uma i-mannin ingehli ushukela, khona-ke ngeke kube nomqondo ovela ku-Diabeteson. Ngiqale ukwehla ngokweqile - okusho ukuthi awekho amaphilisi azosiza. Qiniseka ukuthi ujova i-insulin. I-Type Type 2 sikashukela isiphenduke uhlobo lwesifo sikashukela esibi, ngakho-ke udinga ukuthi ufunde futhi usebenzise uhlelo lokwelapha isifo sikashukela sohlobo 1. Uma kungenakwenzeka ukuthola imijovo ye-insulin yesifo sikashukela esidala, shiya konke njengoba kunjalo bese ulinda ukuthula kube nokuzithoba. Isiguli sizophila isikhathi eside uma sikhanselwa wonke amaphilisi kashukela.
Ukubuyekezwa kweziguli
Lapho abantu beqala ukuthatha i-Diabeteson, ushukela wegazi labo wehla ngokushesha. Iziguli zikuphawula lokhu kuzibuyekezo zazo. Amathebhulethi akhipha modified akavamile ukudala i-hypoglycemia futhi kuvame ukubekezelelwa. Mayelana nesidakamizwa Diabeteson MV akukho ukubukeza okukodwa lapho isifo sikashukela sikhononda nge-hypoglycemia. Imiphumela emibi ehambisana nokuphelelwa ngamandla kwe-pancreatic ayikhuli ngokushesha, kepha ngemuva kweminyaka engu-2-8. Ngakho-ke, iziguli eziqale ukuthatha umuthi muva nje azizishongo.
U-Oleg Chernyavsky
Eminyakeni engu-4 bengilokhu ngithatha ithebhulethi ye-Diabeteson MV 1/2 ekuseni ngesikhathi sasekuseni. Ngenxa yalokhu, ushukela ucishe waba yinto ejwayelekile - ukusuka ku-5.6 kuya ku-6.5 mmol / L. Phambilini ibifinyelela ku-10 mmol / l, ize iqale ukwelashwa ngalo muthi. Ngizama ukukhawulela amaswidi futhi ngidle ngokulinganisela, njengoba udokotela elulekile, kodwa kwesinye isikhathi ngiyayehlise umoya.
Izinkinga zesifo sikashukela ziba khona lapho ushukela ugcinwa uphakanyisiwe amahora amaningi ngemuva kokudla ngakunye. Kodwa-ke, amazinga okushukela we-plasma asheshayo angahlala ejwayelekile. Ukulawula ushukela wokuzila futhi ungawulinganisi amahora ama-1-2 ngemuva kokudla ukuzikhohlisa. Uzoyikhokhela ngokubukeka kokuqala kwezinkinga ezingamahlalakhona. Uyacelwa uqaphele ukuthi amazinga ashukela asemthethweni ashukela kwabanesifo sikashukela ngokweqile. Ebantwini abaphilile, ushukela ngemuva kokudla awukhuphuki ngenhla ka-5.5 mmol / L. Udinga futhi ukulwela izinkomba ezinjalo, futhi ungalaleli izinganekwane ezinoshukela ngemuva kokudla i-8-11 mmol / l. Ukuthola ukulawula okuhle kwesifo sikashukela kungatholakala ngokushintshela ekudleni okuphansi kwe-carbohydrate neminye imisebenzi echazwe kuwebhusayithi yeDiabetes-Med.Com.
Svetlana Voitenko
Udokotela we-endocrinologist wangiyalela ukuba ngibe nesifo sikashukela, kodwa la maphilisi awenza kubi kakhulu. Sekuyiminyaka emibili ngiyithatha, ngalesi sikhathi ngaphenduka isalukazi. Ngilahlekelwe ngama-21 kg. Umbono uyawa, isikhumba siphambi kwamehlo, kwavela izinkinga ngemilenze. Ushukela uyesabeka ngisho ukukala nge-glucometer. Ngiyesaba ukuthi isifo sikashukela sohlobo 2 sesiphenduke uhlobo lwesifo sikashukela esibi.
Ezigulini ezikhuluphele ezinesifo sikashukela sohlobo 2, ezikhipha i-sulfonylurea ziqeda ama-pancreas, ngokuvamile emva kweminyaka eyi-5-8. Ngeshwa, abantu abanciphile nabancanyana bakwenza ngokushesha okukhulu lokhu. Funda i-athikili ngesifo sikashukela se-LADA bese uthatha izivivinyo ezibhalwe kuso. Noma ngabe kukhona ukwehla kwesisindo okungenakuchazeka, khona-ke ngaphandle kokuhlaziywa konke kuyacaca ... Funda uhlelo lokwelapha isifo sikashukela sohlobo 1 bese ulandela izincomo. Khansela i-Diabeteson ngokushesha. Imijovo ye-insulin iyadingeka, awukwazi ukuyenza ngaphandle kwazo.
U-Andrey Yushin
Muva nje, udokotela obengezela engeza ipilisi engu-1/2 ye-metformin kimi, ebengivele ngiyiphathe ngaphambili. Umuthi omusha wabangela umphumela we-atypical side - izinkinga zokugaya. Ngemuva kokudla, ngizwa usizi esiswini sami, ukuqhakaza, ngesinye isikhathi ukushisa kwenhliziyo. Kuliqiniso, isifiso sokudla sehla. Kwesinye isikhathi awuzizwa ulambile nakancane, ngoba isisu sesivele sigcwele.
Izimpawu ezichaziwe aziyona imiphumela emibi yesidakamizwa, kepha inhlanganisela yesifo sikashukela esibizwa ngokuthi yi-gastroparesis, ukukhubazeka okuyingxenye kwesisu. Kwenzeka ngenxa yokungasebenzi kahle kwezinzwa ezingena ohlelweni lwezinzwa oluzimele nokulawula ukugaya. Lesi ngesinye sezimpawu zesifo sikashukela ezinesifo sikashukela. Izinyathelo ezikhethekile kumele zithathwe kule nkinga. Funda isihloko esithi "Diabetesic gastroparesis" ngemininingwane engaphezulu. Kuyaphenduka - ungakususa ngokuphelele. Kepha ukwelashwa kuyinkinga enkulu. Ukudla okunama-carbohydrate aphansi, ukuzivocavoca kanye nemijovo ye-insulin kuzosiza ukujwayeza ushukela kuphela ngemuva kokuthi isisu sakho sisebenze. Isifo sikashukela sidinga ukukhanselwa, njengabo bonke abanye abanesifo sikashukela, ngoba siwumuthi olimazayo.
Iziphetho
Ngemuva kokufunda i-athikili, ufunde konke okudingayo ngomuthi i-Diabeteson MV. Lawa maphilisi asheshe anciphise ushukela wegazi. Manje uyazi ukuthi bakwenza kanjani. Kuchazwe ngokuningiliziwe ngenhla ukuthi Diabeteson MV ihluke kanjani kokuphuma kwe-sulfonylurea kwesizukulwane esedlule. Inezinzuzo, kepha iziphazamiso zisabadlula. Kungcono ukuthi ushintshele ohlelweni lokwelapha isifo sikashukela sohlobo 2 ngokwenqaba ukuthatha amaphilisi ayingozi. Zama ukudla okune-carbohydrate ephansi - kanti ngemuva kwezinsuku ezingama-2-3 uzobona ukuthi ungagcina kalula ushukela ojwayelekile. Asikho isidingo sokuthatha izinto eziphuma ku-sulfonylurea futhi uhlushwa yimiphumela yazo emibi.
