Ngemuva kokuhlinzwa i-pancreatitis, udokotela angakunquma ukusetshenziswa kwe-Getasorb. Lo muthi uyisixazululo esicacile noma esincane esiphuzi sokufakwa.
Into esebenzayo yesidakamizwa yi-hydroxyethyl starch Na + ne-Cl-, chloride yesodium namanzi kuyizinto ezisizayo.
Umuthi unomphumela wokufaka esikhundleni se-plasma uma isiguli sine-hypovolemia nokushaqeka ngenxa yokuhlinzwa, ukulimala, ukusha, ukukhula kwesifo esithathelanayo, nokuphazamisa ukuhamba kwegazi emithanjeni.
Ngabe umuthi usebenza kanjani?
Umuthi osusa esikhundleni se-plasma uqukethe isitashi se-hydroxyethylated. Le nto iyisizinda esiphakeme samangqamuzana aqukethe izinsalela ze-glucose ushukela. Lezi zinto zitholakala kuma-polysaccharides emvelo; amazambane avuthiwe kanye nesitashi sombila asetshenziswa njengomthombo.
Ngemuva kokuthi ikhambi lifakwe emithanjeni, i-amylopectin isheshe ifakelwe amanzi, le nto isisegazini imizuzu engama-20. Ukwengeza ukuqina futhi ukwandise isikhathi somuthi, kusetshenziswa i-hydroxyethylation.
Isitashi sePentac sisiza ukuthuthukisa isimo segazi segazi ngokunciphisa i-hematocrit, ukunciphisa ukubukeka kwe-plasma, ukwehlisa ukuhlanganiswa kwamangqamuzana abomvu egazi, kanye nokubuyisa i-microcirculation ephazamisekile.
Lapho isitashi se-pentac siphathwa ngaphakathi, isithako esisebenzayo siyabhidlika ngaphansi kwethonya le-metabolism eqinile ukwakha izingcezwana eziphansi zesisindo. Umkhiqizo we-metabolic udonswa ngokushesha ezinso.
Iningi lomuthi lishiya umzimba ngomchamo nangaphakathi kwamathumbu ngosuku lokuqala, nezinto ezisele phakathi nesonto.
Izinkomba kanye ne-contraindication
Ngokuhlaselwa kwe-pancreatitis eyingozi, isikhala ngemuva kwe-peritoneum sigcwele uketshezi, okungaholela ku-hypovolemia. Umuthi uyasetshenziswa uma i-hemorrhage ebukhali ibonwa kanye nekhambi le-crystalloid alanele.
Ukwelashwa kwe-GetaSorb kwe-10% no-6% kuyaphikiswa uma kwenzeka kuba ne-hypersensitivity kuma-starches, umfutho we-intracranial, umfutho we-arterial hypertension, ukuphuma kwegazi kwe-intracranial, ukuhluleka okukhulu kwenhliziyo, ukungasebenzi kahle kwezinso, ukuqina kwesibindi, i-cardiogenic pulmonary edema.
Futhi, ukusetshenziswa komuthi akuvunyelwe i-hyperhydrate, i-hypervolemia, ukuphuma komzimba, ukuphazamiseka komzimba okunzima, i-hyperchloremia, i-hypernatremia, i-hypokalemia, i-hemodialysis, izingane ezingaphansi kweminyaka engu-18 ubudala.
- Ukwelashwa ngezidakamizwa kuyenqatshelwa uma kwenziwa inhliziyo evulekile futhi umuntu esesimweni esibucayi.
- Ukuqapha kufanele kusetshenziswe lapho kukhona ukungatholakali okungapheli kokugula, izifo zesibindi ezingapheli, isifo se-Willebrand isifo, i-hemorrhagic diathesis, i-hypofibrinogenemia.
- Ngesikhathi sokukhulelwa, ungasebenzisa umuthi kuphela njengezindlela zokugcina, uma ezinye izindlela zokwelapha zingasizi, kuyilapho izinzuzo zikamama ziphakeme kakhulu kunobungozi obungaba khona kosana olukhulayo. Ngesikhathi sokukhulelwa, ukuncelisa ibele kufanele kushiywe ukuze kungalimazi ingane.
Imiyalo yokusebenzisa umuthi
Ngaphambi kokuqala ukwelashwa, kubalulekile ukuthi uzijwayeze nebhukwana lokufundisa. Umuthi usebenza kuphela lapho kuqala isinxephezelo sevolumu yegazi, ngakho-ke sihanjiswa ngaphakathi nge-dropper ngosuku lokuqala ngemuva kokulahleka kwegazi.
Ukwelashwa kwenziwa ngaphansi kokuqashwa okuqinile kwezokwelapha. Ngokushesha ngemuva kokuthola izinkomba ezinhle, ukumnika kuyamisa.
Imithamo yansuku zonke ebekiwe kanye nezinga lokuphathwa kwekhambi kufanele kuqashelwe ngokuqinile. Okokuqala, i-Geta-Sorb ilawulwa kancane ukuze izinguquko kanye nesimo sesiguli siqashwe. Uma kungenzeka ukusabela kwe-anaphylactoid kwenzeka, ukwelashwa kuyeka ngokushesha.
Udokotela ubeka umgomo ngamunye, agxile esimweni sesiguli, inani legazi elilahlekile, izinga le-hematocrit ne-hemoglobin.
- Lapho usebenzisa ikhambi le-6%, isilinganiso sokufakwa kwesidakamizwa akufanele singeqi ku-20 ml ngehora ngokusekelwe ku-kilogram yesisindo sesiguli.
- Uma kusetshenziswa umuthi ongu-10%, isilinganiso sokungena kakhulu singaba ngu-20 ml ngehora.
- Kubantu asebekhulile, umthamo kufanele ukhethwe ngokucophelela, ngaphandle kwalokho isiguli singaba nokuhluleka kwenhliziyo.
Imiphumela emibi
Ukusabela okuvela eceleni okungalungile kungenzeka uma izingxenye ezingeziwe zegazi zingangezwa. I-dilution engalungile ingathinta kabi ukubangwa kwegazi.
Ezimweni ezingavamile, ukubonakaliswa kwe-hypersensitivity kungenzeka, okungaxhomekeki kumthamo olungiselelwe. I-hematocrit ivame ukuncishiswa bese kuba ne-dilution hypoproteinemia.
Ukweqisa umthamo ophathisiwe kuholela ekuphulweni kokuqina kwegazi, ukwanda kwesikhathi sokuphuma kwegazi. Imisebe iyaqabukela ivele esikhunjeni, kanti ubuso nentamo kubomvu, ukushaqeka, inhliziyo nokuhluleka kokuphefumula kukhula.
- Umsebenzi we-plasma α-amylase wegazi ngezinye izikhathi uyanda, kepha lokhu akusona isibonakaliso sokungasebenzi kahle kwamanyikwe. Imvamisa, ngokuphathwa okuphindaphindiwe kwekhambi usuku lonke, isikhumba esikhanyayo siyakhula.
- Uma umuthi uphathwa ngevolumu enkulu futhi ushesha kakhulu, ukwehluleka okuqinile kwesobunxele be-ventricular kanye ne-edema ye-pulmonary, futhi ukuqina kwegazi kuphazamisekile.
- Lapho kuba nzima ukuthi isiguli siphefumule, sizwa ukuqaqamba esifundeni se-lumbar, ukubanda, i-cyanosis, ngenkathi ukujikeleza kwegazi nenqubo yokuphefumula kuphazamiseka, ukwelashwa kuyeka ngokushesha.
Into esebenzayo yesidakamizwa yandisa i-nephrotoxicity ye-aminoglycoside antibiotics. Ngokuphathwa kanyekanye kwama-anticoagulants, isikhathi sokuphuma kwegazi siyenyuka. Ukuxuba umuthi nezinye izidakamizwa akuvunyelwe.
Faka ikhambi njengoba kushiwo udokotela wakho. Impilo yeshalofu yesisombululo se-6% yiminyaka emi-4, 10% - iminyaka emi-5. I-vial engavuleki igcinwa emazingeni okushisa kuze kube ngama-25 degrees kude nezingane. Ukuqandiswa kotshwala akumele kuvunyelwe.
Intengo yesidakamizwa iphansi futhi ingama-ruble ayi-130 kuphela ngebhodlela le-500 ml. Ungathenga isisombululo sokufakwa ngokumukelwa ekhemisi. Ama-analogues abiza kakhulu afaka i-Voluven, Refortan, HyperKHPP, Infuzol HES, Stabizol, Gemokhes, neVolekam.
Imininingwane yokwelashwa kwe-pancreatitis inikezwe kuvidiyo kule ndatshana.
