I-pancreatic fibrosis (i-pancreatofibrosis) inqubo ye-pathological ebonakala ngokufakwa ngokuphelele kwe-paancyma enempilo ye-pancreatic enezendlalelo noma i-ebalulekile ye-connective (scar) izicubu.
Imvamisa itholakala esigabeni sokugcina sesi sifo esiyisisekelo se-gland futhi ayizivezi.
I-pancreatic fibrosis ingaba izinhlobo ezimbili:
- faka - kukhula uma izinguquko zithinta lonke izicubu ze-glandular;
- ukugxila - lapho kuphela izingxenye zezindawo zezicubu ezixhunyiwe ku-pancreas.
Ngakho-ke, kukhona ama-degree ama-fibrosis amathathu ekukhuleni:
- Kulula: i-gland isebenza ngokujwayelekile, kepha kukhona inani elincane lezinguquko ezithinta i-lobe eyodwa kuphela.
- Medium: Kuvela izimpawu zokushoda okuncane kwe-enzyme, kuthi izilonda ze-fibrous fuse futhi zisakazeke ku-lobules eseduze
- I-Severe (i-diffuse fibrosis): ukuntuleka kwe-enzymatic kuyaqhubeka, ngokulandelana, ngokwanda kwezimpawu zomtholampilo, izicubu zesikhumba zikhula ngokushesha.
Uma esikhundleni sokuncipha, ingxenye ye-parenchymal ye-gland ithathelwa indawo izicubu ze-adipose, khona-ke i-lipomatosis iyakhula.
I-pancreatic lipofibrosis, iyini?
Kukhona nokuhlukahluka okuhlanganisiwe kokuphulwa kwesakhiwo sesitho, lapho kuvela khona izicubu zombili ezihlangene kanye ne-adipose esikhundleni samaseli anempilo. Ibizwa ngokuthi i-lipofibrosis, noma ushintsho lwamafutha e-pancreatic kuma-pancreas.
I-pancreatic fibrosis ivame ukuvela ngokumelene nesizinda se-pancreatitis esibuhlungu noma esingamahlalakhona. Esikhundleni samaseli omisiwe, kuvela izicubu ezingasebenzi ngokuphelele njenge-gland enempilo, i.e. ukungakwazi ukukhiqiza ama-enzyme adingekayo wokugaya ukudla, nama-hormone abalulekile kithi sonke (i-insulin eyaziwayo).
Ngaphezu kwesizathu esikhulu, kunezindlela ezimbalwa zobungozi zalesi sifo:
- i-pathology yesibindi kanye ne-yellow bladder;
- ukukhuluphala;
- ukusetshenziswa kabi kotshwala;
- ukubhema
- ukweqiwa kwemizwa ngokweqile;
- ukuvuthwa nokuguga;
- izifo ezithathelwanayo;
- izifo ezihlelekile zezicubu ezixhunywayo;
- ukudla okungenampilo;
- ukuthatha imishanguzo ethile;
- i-cystic fibrosis - i-pathology enzima yazo zonke izitho zomzimba ezi-exocrine zomzimba, ngokuya ngezigaba zomhlaba wonke zezifo (i-ICD), i-pancreatic fibrosis isho ukubonakaliswa kwe-cystic fibrosis;
- ukunikezwa kwegazi okungalungile kumanyikwe ngenxa ye-atherossteosis.
Izimpawu ze-pancreatossteosis azicaciswanga futhi zibonakala kuphela uma kwenzeka kwanda i-pancreatitis engamahlalakhona. Kwesinye isikhathi isiguli singakwazi ngisho ukunamathisela ukubaluleka kubo, sikholelwa ukuthi lokhu kuyinkinga yokugaya ejwayelekile. Kepha kufanele unake uma kuvela lezo zimpawu, ikakhulukazi uma zingahambi isikhathi eside. Ukuboniswa okunjalo kufaka phakathi:
- Isicanucanu
- Ukwenyuka kokwenza igesi.
- Beka uhudo kuze kube kaningi ngosuku.
- Imizwa engathandeki esiswini esiphezulu.
- Ukwehla kwesisindo.
Izimpawu ezingenhla ziyimpawu yokuvuvukala okungapheli kwe-gland. Zonke ezinye ziyavela kuphela ngenkathi inqubo iqhubeka kakhulu:
- ukugabha, ikakhulukazi ngemuva kwamafutha noma othosiwe;
- Ubuhlungu ezingxenyeni eziphakathi zesisu se-herpes zoster;
- ukwephulwa kokugaya ukudla, ikakhulukazi amafutha (amaconsi amancane wamafutha abonakala esihlalweni).
Uma i-pancreas yenze izinguquko ezinkulu, umtholampilo wesifo sikashukela ungavela ngenxa yokwephula ukuvikelwa kwe-insulin:
- Ukwanda kokuphuma komchamo nsuku zonke;
- Umile njalo;
- Umuzwa womlomo owomile;
- Ukulunywa kwesikhumba;
Ngaphezu kwalokho, isifiso sokudla siyabonakala (kuyaqabukela).
Indlela ephumelela kunazo zonke yocwaningo yi-ultrasound. Kungakhombisa ukuncipha kosayizi be-gland, ukwephulwa kwendlela ejwayelekile yesitho.
Ukuba khona kwezimpawu zomzimba kungakhombisa i-fibroadenoma - isimila esilinganiselwe sama-pancreas kusuka ezicutshini ezihlangene nezishubile.
Ungase futhi ubone izinguquko ze-cystic.
Ngaphezu kwe-ultrasound, udinga ukwenza ukuhlaziya kwegazi nokuhlolwa kwe-biochemical, nquma inani lama-enzymes e-pancreatic.
Lokhu kufaka phakathi:
- i-alpha-amylase (amaprotheni wokugaya);
- i-lipase (ebandakanyeka ekuqhekekeni kwamafutha);
- i-lactase (iphula ushukela wobisi)
Kungenzeka, amazinga we-enzyme azokwehliswa kakhulu.
Kunconywe ukuthi kuhlolwe izindimbane zesiguli lapho kukhona ama-steatorrhea (amaconsi emafutheni). Akulimazi ukubheka izitsha zamanyikwe - ukwenza i-angiography.
Ngezinkomba ezithile, iziguli zithunyelwa i-CT (computed tomography) ne-MRI (i-magnetic resonance therapy), zivumela imininingwane ngesakhiwo se-stroma kanye ne-parenchyma yesitho ngaphansi kwesifundo, ukubona ukwanda noma, mhlawumbe,, ukuncishiswa kwemikhawulo ye-gland.
Ukwelashwa okukhethekile kwe-fibrosis akukakakhiwa. Kepha izimiso eziyisisekelo zihlala zingashintshiwe.
Iziguli kufanele zilandele ukudla okuqinile. Ukudla okunamafutha akuvunyelwe, njengoba kungekho ama-enzyme anele okukugaya. Ukudla okubilisiwe, usawoti, kuphekwe ngaphezulu, ukubhema, nokudla okunezipayisi kufanele kugwenywe. Ziyingozi ngoba zivusa secretion ebalulekile ye-pancreatic juice. Udinga ukudla njalo nangezingxenyana ezincane.
Ukwelashwa kwezidakamizwa kubekiwe kucatshangelwa ubulukhuni nobude besifo. Amalungiselelo we-enzyme asetshenzisiwe afana neMezim-Forte, iCreon, iPangrol, ethuthukisa ukugaya ukudla. Nge-nausea, izidakamizwa ezilwa ne-emetic (ngokwesibonelo, i-metoclopramide), i-antispasmodics (i-No-Shpa) isetshenziselwa izinhlungu ezinzima, nezidakamizwa ezingezona ze-steroidal anti-inflammatory - NSAIDs (Diclofenac, Ibuprofen) zisetshenziselwa ukuvikela izinhlungu ezinzima
Ukwenqaba imikhuba emibi kuyadingeka.
Umuthi wendabuko usiza futhi usize isimo seziguli. Izici zokupholisa amakhambi yi-celandine, i-wort yaseSt. I-wort yase-St John, i-rose hip netiye eliluhlaza kusebenza kahle. Basusa izinhlungu, banciphise imijikelezo, babulale izimila ze-pathogenic, basize ekwelapheni i-cholelithiasis, baqinise ukungatheleleki komzimba jikelele, futhi babe nomphumela wokudambisa (wokulisa). Amanye amakhambi akhuthaza ukukhiqizwa kwe-insulin.
Ukungenelela kokuhlinzwa kwenziwa lapho kukhona ama-neoplasms amabi we-pancreas.
Ngokuncike ekudleni nasekusebenzeni okufika ngesikhathi kwayo yonke imiyalo kadokotela, ukwelashwa kwalesi sifo kuyinto enhle kakhulu.
Ukuvimbela ukuthuthukiswa kokushintsha okungafani nohlobo lwe-fibrosis ne-pancreatic lipomatosis, kubalulekile ukuqala ngokwelashwa kwezifo ezingaphansi kwalo, okwakheka phezu kwalesi sifo. Lezi yizifo ezinjenge-pancreatitis, cystic fibrosis, cholelithiasis, atherosclerosis. Kufanele ubheke njalo ukudla okudlayo, ungadli omningi omnandi nangamafutha, yenza ezemidlalo ukugwema isisindo ngokweqile.
Ukudla okusindayo kunika umthwalo oqinile kumanyikwe, ngakho-ke kufanele uvumele ngokwakho ngezikhathi ezithile.
Imikhuba emibi inethonya elimazayo emzimbeni, futhi ama-pancreas awafani. I-Nikotine ibanga isimo sokudakwa okungamahlalakhona, futhi umthamo omncane wotshwala ungaholela ekunciphiseni i-necrosis ye-gland. Ukudakwa okuhlala isikhathi eside kuholela ekubuyiselweni kancane kancane kwezicubu ezijwayelekile zesikhumba, futhi le nqubo ingahlala iminyaka.
Ukuzivocavoca ngokomzimba nge-pancreatitis kuthuthukisa umsebenzi wepheshana lokuphasa, kwandisa ukuthunyelwa kwama-enzymes, kuqinisa ukuhamba kwesistimu yokugaya ukudla.
Lapho kukhona izifo ezikhona zamanyikwe kanye namapheshana emathunjini, ukuhlolwa kwe-ultrasound kufanele kwenziwe okungenani kanye ngonyaka.
Imininingwane ngezinkinga ze-pancreatitis nezindlela zokwelashwa kwazo inikezwe kuvidiyo ekulesi sihloko.
