Iziguli ezitholakala ngohlobo 2 sikashukela i-mellitus zivame ukubuza ukuthi zithatha kanjani i-glucophage ukufeza umphumela omkhulu wokwelapha? Enye yezidakamizwa ezidumile equkethe i-metformin hydrochloride, i-Glucofage ayisetshenziselwa "isifo esimnandi kuphela". Ukubuyekezwa kweziguli eziningi kukhombisa ukuthi umuthi uyasiza ukunciphisa umzimba.
Isigqi sesimanje sokuphila sikude kakhulu nalokho okunconywe odokotela. Abantu bayekile ukuhamba, bakhetha i-TV noma ikhompyutha esikhundleni semisebenzi yangaphandle, futhi babuyisela ukudla okusheshayo ngokudla okungenamsoco. Le ndlela yokuphila iholela ekubonakaleni kwamakhilogremu angeziwe, bese kuba ukukhuluphala, okuthi noma kunjalo kube yi-harbinger yesifo sikashukela.
Uma ezigabeni zokuqala isiguli singabuyisela izinga le-glucose ngokusebenzisa ukudla okuphansi kwe-carb nokuzivocavoca, lapho ngokuhamba kwesikhathi kuba nzima ngokwengeziwe ukusilawula. Kulokhu, i-glucophage kushukela ikusiza ukunciphisa okuqukethwe ushukela futhi ikugcine ibanga elijwayelekile.
Imininingwane ejwayelekile mayelana nomuthi
Ingxenye yama-Biguanides, i-glucophage isidakamizwa i-hypoglycemic. Ngaphezu kwengxenye eyinhloko, umkhiqizo uqukethe inani elincane le-povidone ne-magnesium stearate.
Umenzi ukhiqiza lo muthi ngendlela eyodwa - kumathebulethi anemithamo ehlukene: 500 mg, 850 mg no-1000 mg. Ngaphezu kwalokho kuneGlucophage Long, okuyi-hypoglycemic esebenza isikhathi eside. Kukhiqizwa ngemithamo efana ne-500 mg ne-750 mg.
Imiyalo ithi umuthi ungasetshenziswa nezinye izidakamizwa ze-hypoglycemic futhi uhlanganiswe nemijovo ye-insulin. Ngaphezu kwalokho, i-Glucofage ivunyelwe izingane ezingaphezulu kweminyaka engu-10. Kulokhu, isetshenziswa ngokwehlukana nangezinye izindlela.
Inzuzo enkulu yesidakamizwa ukuthi iqeda i-hyperglycemia futhi ayiholeli ekuthuthukisweni kwe-hypoglycemia. Lapho i-Glucophage ingena emgudwini wesisu, izinto eziqukethwe kuyo ziyangenwa egazini. Imiphumela eyinhloko yokwelashwa ukusetshenziswa komuthi yilena:
- ukwanda kwe-insulin receptor;
- ukusetshenziswa kweglucose ngamaseli;
- ukubambezeleka kokufaka ushukela esiswini;
- ukukhuthaza kokuhlanganiswa kwe-glycogen;
- ukwehla kwe-cholesterol yegazi, kanye ne-TG ne-LDL;
- kunciphise ukukhiqizwa kweshukela;
- ukuzinza noma ukuncipha kwesiguli.
Akunconywa ukuphuza umuthi ngesikhathi sokudla. Ukudla ngasikhathi sinye kwe-metformin nokudla kuholela ekwehleni kokusebenza kwento. I-Glucophage empeleni ayibophele izingxube zamaprotheni e-plasma. Kumele kuqashelwe ukuthi izingxenye zomuthi empeleni azinakuchaphazeleka ekugayweni komzimba, zithunyelwa emzimbeni yizinso ngezinhlobo ezicishe zingashintshi.
Ukuvimbela imiphumela emibi ehlukahlukene, abantu abadala kufanele bagcine umuthi uphephile kude nezingane ezincane. Ukushisa akufanele kube ngaphezu kwama-25 degrees.
Lapho uthenga umkhiqizo othengiswa kuphela ngomuthi, udinga ukunaka usuku lokukhiqizwa kwawo.
Imiyalo yokusebenzisa umuthi
Ngakho-ke, usebenzise kanjani i-glucophage? Ngaphambi kokuthatha umuthi, kungcono ukubonana nochwepheshe ongakwazi ukuthola imithamo efanelekile. Kulokhu, izinga loshukela, isimo esivamile sesiguli nokuba khona kwama-concomitant pathologies kuyabhekwa.
Ekuqaleni, iziguli zivunyelwe ukuthatha i-500 mg ngosuku noma i-Glucofage 850 mg izikhathi ezingama-2-3. Emavikini amabili kamuva, umthamo wezidakamizwa ungakhuphuka ngemuva kokuvunyelwa udokotela. Kumele kwaziwe ukuthi ekuqaleni ukusetshenziswa kwe-metformin, umuntu onesifo sikashukela angakhononda ngezinkinga zokugaya ukudla. Ukusabela okunjalo okunjalo kwenzeka ngenxa yokuvumelana nomzimba nesenzo sento esebenzayo. Ngemuva kwezinsuku eziyi-10-14, inqubo yokugaya ibuyela kokujwayelekile. Ngakho-ke, ukunciphisa imiphumela emibi, kunconywa ukuhlukanisa umthamo wansuku zonke wezidakamizwa emithanjeni eminingana.
Umthamo wesondlo ngu-1500-2000 mg. Emini, isiguli singathatha kufika ku-3000 mg. Kusetshenziswa imithamo emikhulu, kungakuhle ukuthi abanesifo sikashukela bashintshele ku-Glucofage 1000 mg. Esimweni lapho anqume khona ukusuka kwelinye i-hypoglycemic ejenti aye eGlucofage, okokuqala kufanele ayeke ukuthatha omunye umuthi, bese eqala ukwelashwa ngalo muthi. Kunezici ezithile zokusebenzisa i-Glucofage.
Ezinganeni nasentsheni. Uma ingane indala kuneminyaka eyi-10, ingasiphuza isidakamizwa ngokwahlukana noma ngokuhlangana nemijovo ye-insulin. Umthamo wokuqala ungama-500-850 mg, kanti isilinganiso esiphezulu sifinyelela kuma-2000 mg, okumele ahlukaniswe ngemithamo engu-2-3.
Kwisifo sikashukela esikhulile. Imithamo ikhethwa ngudokotela ngawodwana, ngoba umuthi ungathinta kabi ukusebenza kwezinso kuleli banga. Lapho kuqedwa ukwelashwa ngezidakamizwa, isiguli kufanele sazise udokotela.
Ngokuhambisana nokwelashwa kwe-insulin. Ngokuphathelene ne-Glucofage, imithamo yokuqala ihlala injalo - isuka ku-500 iye ku-850 mg kabili noma kathathu ngosuku, kepha umthamo we-insulin unqunywa ngokusekwe ekuhlolweni kwe-glucose.
I-Glucophage Long: Izici zohlelo lokusebenza
Sesifundile malini ukusebenzisa i-Glucofage yezidakamizwa. Manje kufanele ubhekane nomuthi i-Glucophage Long - amaphilisi wesenzo eside.
IGlucophage Long 500 mg. Ngokuvamile, amaphilisi adakwa ngokudla. I-endocrinologist inquma umthamo odingekayo, kucatshangelwa ushukela wesiguli. Ekuqaleni kokwelashwa, thatha i-500 mg ngosuku (okungcono kakhulu kusihlwa). Ngokuya izinkomba zeglucose yegazi, imithamo yomuthi ingakhuphuka kancane kancane njalo emavikini amabili, kepha kuphela ngaphansi kokuqashwa ngudokotela okuqinile. Umthamo omkhulu wansuku zonke ngu-2000 mg.
Lapho uhlanganisa umuthi ne-insulin, umthamo we-hormone unqunywa ngokuya ngezinga loshukela. Uma isiguli sikhohliwe ukuphuza iphilisi, ukuphindwe kabili komthamo kwenqatshelwe.
I-Glucophage 750 mg. Umthamo wokuqala wesidakamizwa ngu-750 mg. Ukulungiswa komthamo kungenzeka kuphela ngemuva kwamasonto amabili wokuthatha umuthi. Umthamo wokulondolozwa kwansuku zonke uthathwa njenge-1500 mg, kanti esiphezulu - ufike kuma-2250 mg. Lapho isiguli singakwazi ukufinyelela okujwayelekile koshukela ngosizo salo muthi, singashintsha singene ekwelapheni nge-Glucophage ukukhishwa okujwayelekile.
Udinga ukwazi ukuthi abanesifo sikashukela abaphakanyisiwe ukushintshela ekwelashweni nge-Glucofage Long uma besebenzisa i-Glucofage ejwayelekile ngethamo lansuku zonke elingaphezu kuka-2000 mg.
Lapho ushintsha usuka komunye umuthi uye komunye, kuyadingeka ukuthola imithamo efanayo.
Contraindication kanye nemiphumela emibi
Abesifazane abahlela ukukhulelwa, noma asebavele bezala ingane, babekwa umthetho wokuthi basebenzise leli khambi. Ucwaningo oluningi lukhombisa ukuthi umuthi ungathinta ukukhula kwesibeletho. Kodwa-ke, imiphumela yolunye ucwaningo ithi ukuthatha i-metformin akuzange kwandise amathuba okuba nezinkinga enganeni.
Njengoba umuthi ukhishwa ubisi lwebele, akufanele uphuzwe lapho ukhulelwe. Kuze kube manje, abakhiqizi be-glucophage abanalo ulwazi olwanele mayelana nomphumela we-metformin osanda kuzalwa.
Ngaphezu kwalokhu kuphambana, imiyalo enamathiselwe inikezela ngohlu lwezimo kanye nama-pathologies lapho kwenqatshelwe ukuthatha i-Glucophage:
- Ukwehluleka kwangempela nezimo lapho amathuba okusebenza kokuphazamiseka okuvamile kwezinso enyuka khona. Lokhu kufaka izifo ezahlukahlukene, ukushaqeka, ukomisa umzimba ngenxa yokuhanjiswa yisisu noma ukugabha.
- Ukwemukelwa kwemikhiqizo equkethe i-iodine yokuhlolwa kwe-X-ray noma i-radioisotope. Esikhathini esingaphambi nangemva kwamahora angama-48 okusebenzisa kwabo, kwenqatshelwe ukuphuza i-Glucofage.
- Ukwehluleka kwe-hepatic noma ukungasebenzi kwesibindi.
- Ukuthuthukiswa kwe-ketoacidosis yesifo sikashukela, ukoma kanye ne-precoma.
- Hypersensitivity kuzakhi zomuthi.
- Ukuhambisana nokudla okuphansi kwekhalori (okungaphansi kwenkulungwane kcal);
- Ubuthi obunobuthi noma uphuzo oludakayo.
- I-Lactic acidosis.
Njengoba kushiwo ngaphambili, ukuthatha i-Glucophage ekuqaleni kokwelashwa kubangela imiphumela emibi ehambisana nesistimu yokugaya ukudla ecashile. Isiguli singakhononda isicanucanu, ubuhlungu besisu, ushintsho ekunambithekeni, isifo sohudo, kanye nokuntuleka kokudla. Kodwa-ke, kunokunye ukusabela okubucayi okuvela kakhulu esikhathini esingejwayelekile, okungukuthi:
- i-hepatitis kanye nokuqina kwesibindi;
- ukuthuthukiswa kwe-erythema;
- ukuntuleka kwe-Vitamin B12;
- ukuthuthukiswa kwe-lactic acidosis kuhlobo 2 sikashukela;
- ukuqhuma kwesikhumba, ukulunywa.
IGlucophage iyodwa ayiholeli ekunciphiseni ushukela, ngakho-ke, ayithinti ukunakwa kokunakwa kanye nekhono lokushayela izimoto nezinqubo ezahlukahlukene.
Kepha ngokusetshenziswa okuyinkimbinkimbi nge-insulin noma amanye ama-hypoglycemic agents, iziguli kufanele zicabangele amathuba we-hypoglycemia.
Ukuxhumana kwe-Glucophage nezinye izindlela
Lapho usebenzisa lesi sidakamizwa, kubaluleke kakhulu ukwazisa udokotela ngazo zonke izifo ezihlangene. Umcimbi onjalo ungavikela ekuqhamukeni kwemiphumela emibi njengokuthatha izidakamizwa ezimbili ezingahambisani.
Imiyalo enamathiselwe inohlu oluthile lwezidakamizwa ezingavunyelwe noma ezinganconywa uma usebenzisa i-Glucofage. Lokhu kufaka phakathi ama-iodine aqukethe i-iodine umehluko, onqatshelwe ngokuphelele ukuthatha ngesikhathi sokwelashwa kwe-metformin.
Phakathi kwezinhlanganisela ezinganconyiwe kukhona iziphuzo ezidakayo namalungiselelo aqukethe i-ethanol. Ukuphathwa kanyekanye kwabo neGlucophage kungaholela ku-lactic acidosis.
Kukhona nezidakamizwa eziningi ezithinta umphumela we-hypoglycemic we-Glucofage ngezindlela ezihlukile. Ngakho-ke, abanye babo bavusa ukwehla okukhulu kakhulu kwamazinga kashukela, kanti abanye, okuphambene nalokho, babangela i-hyperglycemia.
Izindlela ezithuthukisa umphumela we-hypoglycemic:
- Ama-inhibitors e-ACE.
- Ama-salicylates.
- Insulin
- I-Acarbose.
- Okususelwa ku-sulfonylureas.
Izinto ezenza buthaka izakhiwo ze-hypoglycemic - danazol, chlorpromazine, agaists beta2-adrenergic, corticosteroids.
Izindleko, umbono wabathengi kanye nama-analogues
Lapho uthenga umuthi othize, isiguli asicabangeli nje kuphela umphumela waso wokwelapha, kodwa futhi nezindleko. IGlucophage ingathengwa ekhemisi elijwayelekile noma ibeke i-oda kuwebhusayithi yomkhiqizi. Amanani entengo yomuthi ahlukahluka ngokuya ngohlobo lokukhululwa:
- I-Glucophage 500 mg (amaphilisi angama-30) - kusuka kuma-ruble ayi-102 kuye kwangama-122;
- I-Glucophage 850 mg (amaphilisi angama-30) - kusuka kuma-ruble ayi-109 kuya kwangama-190;
- I-Glucophage 1000 mg (amaphilisi angama-30) - kusuka kuma-ruble ayi-178 kuya kwangama-393;
- I-Glucophage Long 500 mg (amaphilisi angama-30) - kusuka kuma-ruble angama-238 kuya kwangama-300;
- I-Glucophage Long 750 mg (amaphilisi angama-30) - ukusuka kuma-ruble angama-315 kuya kwangama-356.
Ngokusekelwe imininingwane engenhla, kungaphikiswa ukuthi inani lentengo laleli thuluzi aliphezulu kakhulu. Ukubuyekezwa kweziguli eziningi kuqinisekisa lokhu: IGlucophage ingakhokhela wonke umuntu onesifo sikashukela ngemali ephansi naphakathi. Ezinye zezinto ezinhle ukusetshenziswa komuthi yilezi:
- Ukwehliswa okusebenzayo kokuhlushwa ushukela.
- Ukuqiniswa kwe-glycemia.
- Ukuqedwa kwezimpawu zesifo sikashukela.
- Ukwehla kwesisindo.
- Ukusetshenziswa kalula.
Nakhu okunye ukubuyekeza okuhle okuvela kwiziguli. UPolina (oneminyaka engama-51 ubudala): "Udokotela ungibekele lesi sidakamizwa eminyakeni engu-2 eyedlule lapho isifo sikashukela siqala ukuthuthuka. Ngaleso sikhathi anginaso isikhathi sokwenza ezemidlalo, yize nganginamaphawundi awengeziwe. Ngabona i-Glucofage isikhathi eside futhi ngaqala ukubona ukuthi isisindo sami "Ngingasho into eyodwa - lo muthi ungenye yezindlela ezinhle kakhulu zokunciphisa ushukela nokunciphisa umzimba."
I-Metformin itholakala kwezidakamizwa eziningi ze-hypoglycemic, ngakho-ke i-Glucofage inenombolo enkulu yama-analogues. Phakathi kwazo, izidakamizwa ezinjengeMetfogamma, Metformin, Glformin, Siofor, Formmetin, Metformin Canon nezinye zihlukile.
Isiguli esithandekayo, yithi cha kushukela! Uma uthatha isikhathi eside ukuya kudokotela, lesi sifo siyaqhubeka ngokushesha. Uma uphuza i-Glucophage, bambelela kumthamo ofanele. Ngaphezu kwalokho, ungakhohlwa ngokudla okunokulinganisela, ukusebenza komzimba nokulawulwa kwe-glycemic. Le yindlela yokuthola ushukela wegazi ejwayelekile.
I-video ekulesi sihloko izonikeza imininingwane ephelele nge-Glucofage kanye nezinye izidakamizwa ezinciphisa ushukela.
