Lapho udokotela ethola isifo sikashukela esigulini, abanye abantu besaba, abanye babheka "ngethemba", ngoba isayensi ayimile, futhi ihlala ivela. Kunoma ikuphi, wonke umuntu onesifo sikashukela unesithakazelo kulokho okusha ekwelashweni kwesifo sikashukela.
Kumuntu ophile kahle, i-pancreas ikhiqiza inani elifanele le-insulin, elisiza ukulawula ushukela wegazi. Lapho ukusebenza kwesitho kuphazamiseka, isifo sikashukela siyakhula.
Ekhuluma ngesifo sikashukela sohlobo lwesibili, izimfanelo zaso zokuqala azikhiqizi kahle i-hormone emzimbeni, noma ukumelana ne-insulin, okuwukuthi, izicubu ezithambile zilahlekelwa umuzwa wazo ophelele nge-hormone, futhi glucose ayikwazi ukungenwa.
Kuyadingeka ukubheka izindlela zanamuhla zokwelapha isifo sikashukela. Futhi uthole ukuthi yini okusha ekwelashweni kwesifo sikashukela sohlobo 2? Futhi, thola ukuthi ungaselapha kanjani isifo sikashukela sohlobo 1 ngokuya ngamasu akamuva?
Izindlela zokwelapha ezintsha zesifo sikashukela sohlobo 1
I-pathology yohlobo lokuqala iba ngenxa yokuntuleka kokusebenza kwe-pancreatic, futhi i-insulin ye-hormone ayakhiqizwa emzimbeni wesifo sikashukela. Isimo somtholampilo sishubile, izimpawu zithuthuka kakhulu.
Enhlizweni yalesi sifo, njengoba kushiwo ngenhla, ukubhujiswa kwamaseli akhiqiza i-hormone emzimbeni womuntu. Imbangela eholela ekuphazamiseni okunjalo isandulela sofuzo esenzelwe lesi sifo.
Ezenzakalweni zokwelashwa, izindlela zokuqala zengqondo ezivusa amadlingozi zihlukaniswa futhi: ukugula kwesimo segciwane, ukucindezela, ukungezwani komzimba, ukusebenza kokuphazamiseka kwamasosha omzimba.
Ekwelashweni kwesifo sikashukela sohlobo 1, kuye kwavela izindlela ezintsha ezincike kumaseli wesibindi aguquliwe kanye nekhono lazo lokukhiqiza i-insulin ngaphansi kwethonya lezindlela ezithile zokwelapha.
Ekwelashweni kwesifo sikashukela sohlobo 1, izindlela ezilandelayo zingahlukaniswa:
- Ukufakelwa kwamafutha ansundu. Izifundo zemitholampilo zikhombisile ukuthi le nqubo iqinisekisa ukwenziwa kwe-glucose emzimbeni, kunciphisa isidingo semithamo ephezulu ye-hormone.
- Ososayensi baklame idivaysi yaba yisetshenziswa ngendlela ekhethekile yokufunda imininingwane, enquma ukugcwala koshukela egazini kusetshenziswa iphrinta le-laser.
- Kwakhiwa isidakamizwa ngendlela yomjovo osiza amasosha omzimba "afunde" ukuthi angahlaseli amaseli ahlinzeka ukukhiqizwa kwama-hormone emzimbeni. Ngaphansi kwethonya lomuthi, kuvimbela inqubo yezinqubo zokuvuvukala, okuhloswe ukuthi ku-pancreas.
- Ngo-2016-2017, kwakhiwa i-inhaler entsha eyayilimaza i-glucagon ngqo ekhaleni. Kukholelwa ukuthi le divayisi ilula ukuyisebenzisa, futhi intengo yayo ayiphezulu.
Phakathi kwemikhiqizo emisha, umuntu angakhipha inkampani yezidakamizwa iSanofi-Aventis, ebizwa ngeLantus Solontar. Ngokuya ngombono wodokotela, lesi isidakamizwa esinjalo, sibonga ongasinxephezela ngohlobo lokuqala lokugula ngokushesha okukhulu.
Umuthi i-Lg-GAD2 iyithuluzi elihlukile elisiza ukumisa ukuhlaselwa komzimba kumaseli we-pancreatic, ngenxa yalokho kungenzeka ukugcina inani elithile lamaseli asebenzayo.
Uhlobo 2 sikashukela: ukwelashwa ngamasu wakamuva
Lapho sikhuluma ngesifo sikashukela sohlobo 2, singasho ukuthi lesi sifo singumphumela wokusebenza okungasebenzi kahle kwama-receptors abopha i-insulin neglucose. I-Pathology isuselwa kwizizathu eziningi: ukucindezela, utshwala, ukubhema, ukukhuluphala ngokweqile, umfutho wegazi ophakeme, into eyindlalifa.
Izici ezahlukahlukene zangaphandle zinegalelo ekuqhubekeni kwesifo: ukungondleki (ukusetshenziswa kwenani lama-carbohydrate), indlela yokuphila engasebenzi, ukungazivocavoci, ukuvuvukala emzimbeni.
Isisekelo sokwelashwa kwendabuko kufaka phakathi ukudla okuthile kokuphila kahle, okubandakanya imikhiqizo equkethe inani elincane lama-carbohydrate nesitashi. Ngaphezu kwalokho, ukunxephezela isifo sikashukela, ukusebenza ngokomzimba kwesiguli kuyadingeka ukusiza ukuthuthukisa ukutholakala kweseli kwe-insulin.
Izindlela ezintsha ezilandelayo ziye zavela ekwelashweni kwesifo sikashukela sohlobo 2:
- Idivaysi ye-Magnitoturbotron inikezela ngokwanda kwe-oksijini negazi kwezicubu zomzimba, futhi ijwayele ukuhamba kwegazi ngokwejwayelekile. Ucwaningo luye lwabonisa ukuthi ngokusebenzisa izinsiza kusebenza, ushukela uzinza ezingeni elifanele.
- Ukwelashwa kwesifo sikashukela sohlobo 2 nge-laser therapy kanye ne-cryosauna. Lezi zindlela zisiza ukukhulisa ukuzwela kwamangqamuzana kuyi-hormone.
Naphezu kweqiniso lokuthi kuvela okuthile okusha ekwelashweni kwesifo sikashukela sohlobo 2, iphoyinti elisebenzayo lokuzivocavoca lingumzimba wokugcwalisa umzimba nge-oxygen, ukunciphisa umthwalo kumanyikwe.
Izidakamizwa ezilandelayo zesizukulwane esisha zisetshenziselwa ukwelapha isifo sikashukela sohlobo 2:
- Okususelwa ku-sulfonylureas.
- IBiguanides.
- I-Glitazones.
- Ama-Gliptins.
Iqembu lososayensi baseMelika lenze inqubo entsha esiza ukuvikela ukukhula kwamafutha asezinhlizweni zenhliziyo kanye nezicubu zomzimba, ngenxa yalokho amangqamuzana awalahli amandla awo e-hormone.
Ukuqhekeka ekwelashweni kwesifo sikashukela kulele ekutheni kungenzeka ukuthi alahle i-insulin yemvelaphi yezilwane, futhi kwenziwa ukuguqulwa kwe-hormone yofuzo.
Ukwelashwa Okusha Kwesifo Sikashukela
Ukugcwala ngokweqile, izingcindezi yizimbangela ezivelele zokuthuthuka kwe-pathology yohlobo lwesibili. Lapho umuntu enovalo, umzimba uqala ukukhiqiza kakhulu i-adrenaline ne-norepinephrine.
Lawa mahomoni asetshenziswa nge-oksijini, ngakho-ke kuyadingeka kakhulu, futhi umsebenzi wenyama ungakunikeza lokhu. Kodwa-ke, umhlaba wanamuhla awukuvumeli njalo ukuthi wabele ihora ngosuku ukuze ulisebenzise kwezemidlalo.
Kulesi simo, ososayensi bakhiqize idivaysi ekhethekile enikezela ngemisebe yamandla kazibuthe, ngenxa yalokho ukusebenza kwawo wonke amalungu angaphakathi nezinhlelo kusebenza.
Noma kunjalo, i-magnetotherapy ine-contraindication yayo:
- Ama-tumor masisi.
- Ukwanda kokushisa komzimba.
- Isifo sofuba
- I-hypterension ye-Arterial.
- Ukukhathala komzimba.
- Isikhathi sokukhulelwa.
I-Glitazones yimithi ethile ekhulisa ukwanda kwezicubu ze-hormone. Thatha amaphilisi ngesikhathi sokudla ngoketshezi oluncane.
Naphezu kokusebenza kahle kwemishanguzo, akunakwenzeka ukwelapha isifo sikashukela. Ngaphezu kwalokho, banezindlela ezithile ezimbi zokuphendula: ukuvuvukala, ukukhubazeka okwandayo kwamathambo, inzuzo yesisindo.
Contraindication ziyi-pathologies yesibindi nezinso, isikhathi sokukhulelwa nokuncelisa ibele.
I-Autohemotherapy
I-Autohemotherapy yindlela entsha yokwelashwa kwesifo sikashukela, eyasungulwa ngonyaka we-2017. Ngokusho kososayensi, lokhu kwelashwa kuzosiza ukunqoba lesi sifo ezinganeni nasezigulini zabantu abadala.
Umongo wenqubo unje: I-5 ml yegazi ithathwa enganeni noma kumuntu okhulile, ngemuva kokuthi ixubene no-55 ml wesisombululo esithile, khona-ke lapho ingxube yonke ididiyelwe yaba ngama-5 degrees.
Izinga lokushisa elijwayelekile lomzimba womuntu lingama-37 degrees, kuthi lapho selehlile libe ngama-degree ama-5, kuqhamuke ukushaqeka okushisayo, okuqinisekisa ukulungiswa kwezinqubo ze-metabolic kanye nokuhlukahluka kofuzo.
Izici zenqubo:
- Umxube wethulwa emzimbeni wesiguli, okuvumela ukuthi ulungise kancane kancane izinqubo eziphazamisekile.
- Isikhathi sokwelashwa siyizinsuku ezingama-60.
Lo mgomo kukholakala ukuthi mkhulu kunomuthi ojwayelekile. Njengoba sekushiwo ukuthi umuthi wokugoma uyasiza ekwelapheni isifo sikashukela, esiye sabonwa esigulini iminyaka eminingi. Ngaphezu kwalokho, ingamisa izinkinga zesifo sikashukela - ukungaboni kahle, ukuhluleka kwezinso, nabanye.
Ukukhuphela eceleni imiphumela emibi engenzeka kulokhu kwelashwa, isiguli kufanele silandele ngokuqinile konke ukunconywa kukadokotela. Kanye nemithi, kuphoqelekile ukuhambisana nokuzivocavoca ukwelashwa kwesifo sikashukela nokudla okunempilo.
Ngokusobala, ngeke kushiwo ukuthi lokhu kuyindlela yokwelapha i-100% yesifo sikashukela okwamanje, njengoba namanje kusenziwa izivivinyo.
Kodwa-ke, le ndlela inelungelo lokuphila, futhi imiphumela yokuqala iyathandeka.
Isifo Sikashukela Sikashukela
Enye indlela entsha yokwelapha isifo “esimnandi” ngokusebenzisa ukwelashwa kwamangqamuzana. Lokhu kwelashwa kususelwa endaweni yokubuyiselwa kwamaseli we-pancreatic owonakele namanye amaseli we-stem.
Umphumela walokhu kunyakaziswa ukuthi lapho amaseli eshintshwa esikhundleni, ama-pancreas ebuyiselwa, aqala ukusebenza ngokugcwele, i-insulin ikhiqizwa ngenani elifanele.
Kulesi simo, kuveza ukuqina kwamasosha omzimba womuntu, kuvela imithambo yegazi emisha nemithambo yemithambo yegazi, imithambo yegazi yakudala eyonakele ibuyiselwe, iba namandla futhi ibe namandla.
Ngokusebenzisa le ndlela ekwelapheni isifo sikashukela, umuntu angafinyelela amazinga ajwayelekile kashukela emzimbeni womuntu, futhi azinzise ngezinga elidingekayo.
Izici zokwelapha i-stem cell yesifo sikashukela:
- Kusetshenziswa inalithi encane, umongo wethambo likashukela uthathwa.
- Ngemuva kwalokho, amaseli we-stem ahlukaniswe nezinto ezibonakalayo.
- Ngokusebenzisa i-catheter, amaseli angeniswa esigulini.
Umphumela wenqubo ungazwakala ngemuva kwezinyanga ezimbalwa. Izifundo zaselabhorethi zibonisa ukuthi ngemuva kokufakwa kwamaseli, i-hormone synthesis emzimbeni wejwayelekile, futhi amanani kashukela ancipha.
Ngaphezu kwalokho, ukwelashwa kwezilonda ze-trophic nezinkinga zesikhumba kuyabonakala, ukuhamba kwegazi kuyathuthuka, ukugcwala kwe-hemoglobin namaseli ebomvu egazini kuyanda.
Sengiphetha, kungaphethwa ngokuthi ukwelashwa kwesifo sikashukela sohlobo 1 ngaphandle kwe-insulin kungenzeka futhi sekuvele izindlela ezintsha zokwelashwa kwesifo sikashukela. Kodwa-ke, ngeshwa, akusona isiqinisekiso se-100% sokwelashwa okuphelele. Ngakho-ke, kanye nabo, awudingi ukuyeka ukwelashwa kwendabuko.
Kuvidiyo ekulesi sihloko, udokotela uzoqhubeka nesihloko sokwelashwa okusha kwesifo sikashukela.
