Ukusetshenziswa kwe-Berlition yezidakamizwa sikashukela kuvimbela ukukhula kwe-polyneuropathy.
I-Diabetesic polyneuropathy yisifo esenzeka ezigulini ekuqaleni kokukhula kwe-pathology noma isikhathi eside ngaphambi kokuboniswa kwayo kokuqala. Kuboniswa ukwehla kwendawo ekuhlinzekweni kwegazi (ischemia), kanye nokuphazamiseka kwe-metabolic ku-nerve. Ngaphezu kokuvimbela i-polyneuropathy, isidakamizwa sithuthukisa ukusebenza kwesibindi, i-metabolism ye-lipids nama-carbohydrate.
Wonke umuntu wesibili onesifo sikashukela kungekudala uzizwa evela kudokotela ngokukhula kwe-polyneuropathy syndrome. Abantu abaningi bafunda ukungasebenzi kahle kwesibindi, kufaka phakathi i-pathologies ebucayi (i-cirrhosis, i-hepatitis). Ngakho-ke, kunesidingo sokuvinjwa kwezifo ezikhula ngemuva kwesifo sikashukela.
Muva nje, izidakamizwa ezimbili sezithole ukuthandwa - i-Berlition ne-Thioctacid, ezinomphumela ofanayo wokuvimbela isifo sikashukela se-polyneuropathy. Le ndatshana izokusiza uthole ukuthi yikuphi okungcono - i-Berlition noma i-Thioctacid?
Izici ze-Pharmacological zezidakamizwa
Njengoba izidakamizwa ziyafana, ziqukethe isakhi esiyinhloko - i-alpha lipoic acid (amanye amagama - i-Vitamin N noma i-thioctic acid). Inezakhiwo ze-antioxidant.
Kumele kuqashelwe ukuthi i-alpha-lipoic acid iyafana emthonjeni we-biochemical kumavithamini eqembu B. Wenza imisebenzi ebalulekile:
- I-alpha-lipoic acid ivikela ukwakheka kweseli ekulimaleni kwe-peroxide, inciphisa amathuba okuthuthuka kwe-pathologies enkulu ngokubopha ama-radicals wamahhala, futhi ngokuvamile kuvimbela ukuguga komzimba ngaphambi kwesikhathi.
- I-Alpha lipoic acid ibhekwa njenge-cofactor ebamba iqhaza kwinqubo ye-mitochondrial metabolism.
- Isenzo se-thioctic acid sihlose ukunciphisa ushukela wegazi, ukukhulisa i-glycogen esibindini kanye nokunqoba ukumelana ne-insulin.
- I-Alpha lipoic acid ilawula ukusebenza kwe-carbohydrate, lipids kanye ne-cholesterol.
- Ingxenye esebenzayo ithinta kahle izinzwa zepherishi, ithuthukisa isimo sayo sokusebenza.
- I-Thioctic acid ithuthukisa ukusebenza kwesibindi, ivikela umzimba emiphumeleni yezici zangaphakathi nezangaphandle, ikakhulukazi utshwala.
Ngaphezu kwe-thioctic acid, i-Berlition ifaka izinto eziningi ezingeziwe: i-lactose, i-magnesium stearate, i-croscarmellose sodium, i-microcrystalline cellulose, i-povidone ne-hydrated silicon dioxide.
I-Thioctacid yezidakamizwa, ngaphezu kwengxenye esebenzayo, iqukethe inani elincane le-hydroxypropyl cellulose elifakwe endaweni ephansi, i-hydroxypropyl cellulose, i-hypromellose, i-magnesium stearate, i-macrogol 6000, i-titanium dioxide, i-quinoline aphuzi, i-indigo carmine ne-talc.
Umthamo wezidakamizwa
Okokuqala, kufanele kuphawulwe ukuthi ukusetshenziswa okuzimele kwezidakamizwa kwenqatshelwe ngokuphelele. Ungathenga kuphela umuthi ngokuya ngencazelo ebekwe ngudokotela ngemuva kokubonisana.
Izwe okwenziwa kulo umuthi iBerlition yiJalimane. Lesi sidakamizwa senziwa ngendlela yama-ampoules angama-24 ml noma amaphilisi angama-300 ayi-600 mg.
Amathebulethi athathwa ngomlomo, awadingi ukuhlafunwa. Umthamo wokuqala ungama-600 mg kanye ngosuku, okungcono ngaphambi kokudla esiswini esingenalutho. Uma isiguli esinesifo sikashukela sinezinkinga zokungasebenzi kahle kwesibindi, sinqunywa sisuka ku-600 siye ku-1200 mg wesidakamizwa. Lapho umuthi uphathwa ngokuhlinzwa ngendlela yesisombululo, kuqala uhlanjululwe nge-0.9% sodium chloride. Ukufakwa kwemiyalo kungatholakala ngemininingwane eminingi nemithetho yokusebenzisa umuthi njengabazali. Kufanele kukhunjulwe ukuthi inkambo yokwelashwa ayinakwelulwa isikhathi esingaphezu kwamasonto amane.
I-Thioctacid yezidakamizwa ikhiqizwa yinkampani yezokwelapha yaseSweden iMeda Pharmaceuticals. Ikhiqiza umuthi ngezindlela ezimbili - amaphilisi angu-600 mg nekhambi lomjovo lama-24 ml kuma-ampoules.
Imiyalo ikhombisa ukuthi umthamo ofanele unganqunywa kuphela uchwepheshe ohambela. Umthamo wokumaphakathi wokuqala yi-600 mg noma i-1 ampoule yesisombululo esikhishwa ngaphakathi. Ezimweni ezinzima kakhulu, kungabekwa ama-1200 mg noma ama-ampoules ama-2. Kulokhu, inkambo yokwelashwa iqala kumaviki amabili ukuya amane.
Uma kunesidingo, ngemuva kwenkambo yokwelashwa, ikhefu lanyanga zonke lenziwa, bese isiguli sishintshela ekwelashweni ngomlomo, lapho umthamo wansuku zonke ungama-600 mg.
Contraindication kanye nemiphumela emibi
I-Thioctacid ne-Berlition isetshenziswa ekwelapheni i-polyneuropathy yotshwala nesifo sikashukela, ukudakwa ngosawoti wezinsimbi ezisindayo, ukungasebenzi kahle kwesibindi (i-cirrhosis, i-hepatitis), ukuvikela i-coronary atherosulinosis ne-hyperlipidemia.
Kwesinye isikhathi ukusetshenziswa kwezimali kuba yinto engenzeki ngenxa yokuba khona kwe-contraindication ethile noma ukusabela okungalungile. Ngakho-ke, abantu abanokuqonda ngakunye kwezakhi zezidakamizwa, abesifazane abakhulelwe nabomama asebekhulile banqatshelwe ngokuphelele ukusebenzisa i-Thioctacid noma i-Berlition. Ngokuqondene nobuntwana, izifundo mayelana nemiphumela yezidakamizwa emzimbeni osemusha azenziwanga, ngakho-ke ukuthatha izidakamizwa kuvunyelwe kusuka kwabaneminyaka eyi-15 kuphela.
Kwesinye isikhathi ngokusetshenziswa kabi kwezidakamizwa noma ngesizathu esithile, imiphumela emibi iba khona. Njengoba izidakamizwa i-Thioctacid ne-Berlition ziyefana emiphumeleni yazo yokwelapha, zingadala imiphumela emibi ecishe ifane:
- ehlobene nohlelo oluphambili lwezinzwa: idiplopu (umbono okhubazekile, "isithombe esiphindwe kabili"), ukungasebenzi kahle kokunambitha, ukwehluleka;
- kuhlotshaniswa namasosha omzimba: ukungezwani komzimba, okubonakaliswa ukuqhuma kwesikhumba, ukulunywa, i-urticaria, kanye nokushaqeka kwe-anaphylactic (okungavamile kakhulu);
- kuhlotshaniswa nohlelo lwe-hematopoietic: i-hemorrhagic rash, thrombocytopathy noma i-thrombophlebitis;
- kuhlobene ne-metabolism: Ukwehla okuncane kwe-glucose yegazi, kwesinye isikhathi ukuthuthukiswa kwe-hypoglycemia, kuboniswa ukukhuphuka kokujuluka, ikhanda kanye nesiyezi, umbono ongashayi emhlolweni;
- ezihambisana nokuphendula kwasendaweni: umuzwa ovuthayo endaweni yokuphathwa kwezidakamizwa;
- ezinye izinkomba: ukukhuphuka kwengcindezi ye-intracranial kanye nokuphefumula.
Njengoba ukwazi ukubona, ukusetshenziswa kwezidakamizwa kuhlala kunobungozi obuthile bokuthi kube nezinkinga ezinkulu. Uma isiguli siqaphele okungenani eyodwa yalezi zibonakaliso ezingenhla, kuyodingeka sifune usizo lodokotela ngokuphuthumayo.
Kulokhu, udokotela ubukeza uhlobo lonyango lwesiguli futhi enze izinguquko ezithile.
Izici zokuqhathanisa zezidakamizwa
Ngaphandle kokuthi izidakamizwa zine-alpha lipoic acid futhi zinomphumela ofanayo wokulapha, zinezici ezithile ezihlukanisayo. Kungathinta ukukhethwa kukabili udokotela nesiguli sakhe.
Ngezansi ungathola mayelana nezici ezisemqoka ezithinta ukukhetha kwemithi:
- Ukuba khona kwezinto ezengeziwe. Njengoba amalungiselelo aqukethe izinto ezihlukile, angabekezelelwa yiziguli ngezindlela ezihlukile nazo. Ukunquma ukuthi imuphi umuthi ongenazo ezinye izinto ezimbi, kuyadingeka ukuzama zombili lezi zidakamizwa.
- Izindleko zemithi nazo zidlala indima enkulu. Isibonelo, inani lentengo elijwayelekile le-Berlition (ama-ampoules ama-5 we-24 ml ngamunye) ngama-ruble angama-856 aseRussia, kuthi iThioctacid (5 ampoules of 24 ml ngayinye) ngama-ruble angamaRussia ayi-1,559. Kuyacaca ngokushesha ukuthi umehluko ubalulekile. Isiguli esinemivuzo ephakathi naphansi kungenzeka ukuthi sigxile ekukhetheni umuthi oshibhile onomphumela ofanayo.
Ngokuvamile, kungaphawulwa ukuthi izidakamizwa i-Thioctacid ne-Berlition zinomphumela omuhle emzimbeni womuntu ngazo zombili izinhlobo 1 zikashukela sohlobo 2. Zombili lezi zidakamizwa zingeniswa futhi zenziwa yizinkampani ezenza umuthi ezihlonishwayo kakhulu.
Ungakhohlwa mayelana ne-contraindication kanye nokulimala okungaba khona kwezidakamizwa. Ngaphambi kokuzithatha, udinga ukubonisana nodokotela wakho.
Lapho ukhetha inketho enhle kakhulu, kufanele ugxile ezintweni ezimbili - intengo kanye nokuphendula ezingxenyeni ezakha imishanguzo.
Uma isetshenziswa kahle, i-thioctacid kanye ne-Berlition kuzosiza ukuvikela ukuthuthukiswa kwe-polyneuropathy yesifo sikashukela kuphela, kepha futhi nezinye izingqinamba eziyingozi zohlobo 2 nohlobo lwe-1 mellitus yesifo sikashukela esihambisana nomsebenzi wesibindi nezinye izitho zomzimba. Ividiyo ekulesi sihloko ikhuluma ngezinzuzo ze-lipoic acid.
