I-lipodystrophy iyatholakala uma umuntu engenawo amanoni. Ngasikhathi sinye, ukudla okwelapha okunconywe udokotela akunikezi umphumela, izinga lamafutha alikhuphuki ngisho nangemva kokudla ukudla okunekhalori ephezulu. Ngalesi sifo, ubudala bomuntu kanye nobulili bakhethi, noma kunjalo, izimpawu zingahluka emadodeni nakwabesifazane.
Akukhathalekile ukuthi kudliwa yini isiguli, inani lama-carbohydrate, amafutha kanye namaprotheni. Futhi akatholi isisindo ngokungabikho okuphelele kokuhlangenwe nakho, ukusebenza ngokomzimba, imidlalo esebenzayo.
I-Lipodystrophy iyindlela yokusebenza eyingozi, inikeza imiphumela emibi nezinkinga, ngoba ama-lipid abamba iqhaza ezinqubweni ezibalulekile ze-metabolic emzimbeni womuntu, abalulekile.
Umehluko oyisisekelo kusuka ku-dystrophy esejwayelekile ukuthi ukulahleka kwemisipha akwenzeki. Ngokubukeka, umuntu akabukeki ekhathele, kepha ngaphandle kokwelashwa, ukuphazamiseka ekusebenzeni kwezitho zangaphakathi nezinhlelo kuzoqala.
Izinhlobo ze-lipodystrophy, izici zazo
Kuyisiko ukwahlukanisa izinhlobo eziningana zalesi sifo. Kuqabukela kakhulu ukuxilonga i-lipodystrophy ye-congenital generalized, emafutheni wengane atholakala kuphela ekhanda nasezinyaweni zemilenze. Uhlobo lwendabuko yendabuko yande ngokwenzeka ngokwengeziwe, kulezo ziguli idiphozi yamafutha isentanyeni, ebusweni nase esifubeni. Lesi sifo senzeka kwabesilisa nabesifazane banoma yimuphi unyaka.
Akuvamile ukuthi kutholakale i-lipodystrophy, kuthinta abesifazane kuphela. Izici ezihlukanisayo - ukungabikho ngokuphelele kwamafutha, kuqala ukunyamalala ngesikhathi sokuthomba. Cishe njalo, iziguli zinenkinga yezinso.
Enye into yi-lipodystrophy ejwayelekile, kwenzeka ngenxa yokudluliswa kwezifo ezithathelanayo: i-hepatitis, inyumoniya, i-diphtheria. Lapho emzimbeni kukhona ukwephulwa kokusebenza kwe-hepatocytes ebhekele izinqubo ze-metabolic, ukuwohloka kwamafutha, i-hepatic lipodystrophy kuqala kumuntu.
Kudingeka kakhulu ukwahlukanisa i-lipodystrophy ku-mellitus (insulin lipodystrophy), kwenzeka ngenxa yemijovo ejwayelekile ye-insulin. Indawo lapho umjovo uvame ukunikezwa khona isikhathi esithe xaxa:
- i-atrophy;
- wanyamalala.
Kwi-pathogenesis yalolu hlobo lwe-lipodystrophy, ukubaluleka okuthile kunikezwa ekuhlukumezeni isikhathi eside ezicutshini, ukuqiniswa kwezinzwa zepherishi ngenxa yokucasuka kwe-physicochemical, mechanical and thermal. Kuyiphutha futhi ukungabandakanyi indima yokusabela kwendawo lapho kulawulwa khona ama-hormone.
Odokotela banesiqiniseko sokuthi umzimba wezinye iziguli uphendula imijovo ngemuva kwemithamo embalwa ye-insulin. Kodwa-ke, ngobuningi obukhulu bamacala, le ndlela ye-lipodystrophy iba kuphela iminyaka eyi-10-15 ngemuva kokuqala kwenkambo yokwelashwa. Ukujula kwezilonda kungahluka kusuka kumamayela ambalwa ukuya ekungabikho ngokuphelele kwezicubu ezingaphansi kwezindawo ezinkulu zomzimba.
Namuhla, zonke izinto ezingathinta ushintsho enanini lamafutha azikasungulwa. Izimbangela ezingenzeka kakhulu ukuphazamiseka kwe-metabolic, kufaka phakathi ama-hormone, umlutha (ukubhema, ukusebenzisa kabi utshwala), i-giardiasis, isifo sokusha kwesibindi, ukudla ukudla okunamafutha noshukela kanye nokudla okungenampilo.
Imbangela ecace ngokulinganayo ye-lipodystrophy ukudakwa komzimba, lokhu kufaka:
- ubuthi ezimbonini eziyingozi;
- ukuhlala isikhathi eside ezindaweni ezinomnotho omubi.
Lapho udokotela ethole i-lipodystrophy yesifo sikashukela, izimbangela ngokuvamile kufanele zifunwe ngemijovo ye-insulin ejwayelekile.
Ukwelashwa kwe-pathology
Ngemuva kokuhlolwa kokuqala, udokotela utusa ukuthi kwenziwe ukuhlolwa kwelabhoratri, lokhu kuhlaziya okujwayelekile komchamo negazi, ukuhlaziya kwezinga le-glucose emzimbeni. Ngemuva kokuthi i-lipodystrophy ihlotshaniswe ne-pathologies ekhona, qala inkambo yokwelapha.
Uma umuntu egula isifo sikashukela, akunakuphikwa ukuthi umuntu angabunaka ubukhona be-lipodystrophy, ngoba izicubu ze-atrophied azikuvumeli ukungena kwe-insulin ngemuva komjovo. Ngenxa yalokhu, kuba yinkinga ukubala kahle umthamo we-hormone, okufanele ungene emzimbeni wesiguli.
Isifo sikashukela se-Lipoatrophic siyingozi ikakhulukazi, isimo lapho izicubu zesifo sikashukela ziyeka ngokuphelele ukuphendula i-insulin. Le nkinga ibonwa cishe i-25% yabantu abanesifo sikashukela. Izinguquko ze-atrophic esikhunjeni azisongeli kangako. Amaseli wamafutha aminyene aqongelela ezindaweni zokulimala, lapho le ndawo ilimala noma ukungena kwegciwane kungena kuyo, amathuba okuba nezilonda eziyizidudla, unyawo lwesifo sikashukela lukhuphuka kakhulu, ukubonakala kwengqinamba - i-gangrene inabetes mellitus.
Lapho i-lipodystrophy ibuye ibe yinkimbinkimbi ngohlobo lwesifo se-hepatic, kubuye kuvezwe ukwelapha ngezidakamizwa:
- ama-hepatoprotectors (ama-Essliver, abalulekile);
- ukukhuthaza i-metabolism (methionine, methyluracil);
- amavithamini ayinkimbinkimbi.
Uma kunezikhalazo ze-colic, udokotela unquma i-antispasmodics. Ezimweni ezinzima kakhulu, ukwelashwa kwama-hormone ngeke kusatshalaliswe ngakho.
Imvamisa, ukubuyiselwa kwesibindi kuthatha okungenani izinyanga eziyi-6, khona-ke okungenani iminyaka emi-2 ilandelana, kuzodingeka unake ngokukhethekile ukondleka, uthathe izidakamizwa ukuze ulondoloze umzimba.
Kwesinye isikhathi ukwelashwa kuqala ngokushintsha kohlobo lwe-insulin, i-multicomponent noma i-insulin yomuntu kuzoba ngempumelelo kakhulu. Umjovo wenziwa emngceleni wezicubu ezinempilo ne-lipodystrophy. Uma ulandela inqubo yomjovo, faka ama-insulin afanele nge-pH engathathi hlangothi, i-lipodystrophy ayakhi.
Ukuvimbela umthombo wokucasulwa futhi wenze i-trophism iguquguquke, kusetshenziswa ingxube ye-insulin eneNovocaine. I-hormone ixubene ne-0.5% Novocaine solution, izindawo ezithinteke yi-lipodystrophy zigcwele ngengxube.
Izindlela zokuvimbela
Ukususa imiphumela enjalo kunzima kakhulu, cishe akunakwenzeka.
Ukuphela kwendlela yokuzivikela ukuvikela ngesikhathi.
Ukuze ungathuthukisi i-lipodystrophy ku-mellitus yesifo sikashukela, kufanele uqaphe njalo ukudla okudlayo, ungafaki ukusetshenziswa:
- ama-carbohydrate asheshayo;
- ukudla okunamafutha.
Kunconywe ukuthi wenze izifundo eziningana ze-ultrasound, inductometry. Isikhathi sokuqala okudingeka uchithe ngaso izikhathi eziyi-10-15, ukwelashwa kwenziwa njalo nangolunye usuku. Ngemuva kwesifundo ngasinye, bathatha ikhefu lezinyanga ezingama-2-3 bese kuphinda kudlule ezinye izikhathi eziyi-15.
I-Ultrasound iyakwazi ukungena kwezicubu ngamasentimitha ayi-10, ukunyakaza kusiza ukwenza ngcono isimo sesikhumba, kuvuse ukuhamba kwegazi. Ngesikhathi senqubo, i-hydrocortisone yamafutha isetshenziswa esikhunjeni, kuyasiza ukubuyisela izicubu ezithintekile. Njengomthetho, izinyathelo ezihlongozwayo zisiza ukuvikela ukubonakaliswa kwe-lipodystrophy isikhathi esiyizinyanga eziyisithupha kuya eminyakeni emibili.
Kuyasiza ekuvimbeleni ukushintshanisa amasayithi womjovo; i-insulin ilawulwa kuphela ngokulungiswa okufudunyezwayo kuze kufike ekushiseni komzimba. Kuboniswa futhi nokuphatha amasayithi womjovo ngotshwala, ngemuva kokuthi umjovo uwesule ngendwangu eyinyumba noma ulinde utshwala buvele.
I-insulin ifakwa ngokujulile futhi kancane kancane ngaphansi kwesikhumba, kuyenqatshelwe ngokuphelele ukusebenzisa izinaliti ezindala, zilimaza isikhumba ngisho nangokwengeziwe.
