Ubudlelwano phakathi kwe-hypothyroidism kanye nesifo sikashukela akuqondile. Indlala yegilo ingaba nokuphazamiseka kuzindlela ezi-2 - Amangqamuzana e-gland gland angakhiqiza kakhulu noma mancane kakhulu.
Indlala yegilo ikhiqiza ama-hormone amabili, i-thyroxine ne-triiodothyronine. Lawa ma-hormone afushaniswa njengo-T 3 no-T 4.
Ekwakhiweni kwamahomoni, kusetshenziswa iodine ne-tyrosine. Ukuze kwakheke ama-T 4, ama-molecule ama-iodine ama-4 ayadingeka, kuthi i-hormone T3, kudingeka ama-molecule ama-3.
Izimpawu ze-hypothyroidism emzimbeni womuntu
Ngokuphikisana nesizinda sokuthuthuka kwe-hypothyroidism ezigulini ezinesifo sikashukela noma kubantu abanokucacisa okuthile kuso, kuzoba nezinkinga ezilandelayo:
- Ukusebenza kahle kokusebenza kwe-lipid metabolism emzimbeni. Egazini kukhona ukwanda kwenani le-cholesterol, futhi inani lamafutha aphilile ancishiswa kakhulu.
- Izilonda ze-Vascular, ukwehla kwe-lumen yangaphakathi. Iziguli zithola ukuthuthukiswa kwe-atherosclerosis ne-stenosis, okufaka engcupheni eyengeziwe yokuhlaselwa yisifo senhliziyo nokushaywa unhlangothi.
Ukuphazamiseka okutholakala nge-hypothyroidism ngesikhathi sokukhula kwesifo sikashukela kungavusa ukushaya kwenhliziyo noma unhlangothi, ngisho nakubantu abasha.
Ekuthuthukiseni i-hypothyroidism, ukubonakala kwezimpawu ezilandelayo kuyisici:
- ukukhuluphala ngokweqile kuvela;
- uhlelo lwenhliziyo lubamba kancane;
- ukuqunjelwa ngezikhathi ezithile;
- ukukhathala kuyavela;
- ukungahambi kahle kokuya esikhathini kwabesifazane kuyakhula.
Endabeni yokuthuthuka kwe-hypothyroidism ngasikhathi sinye nokukhiqizwa kwe-insulin engasebenzi kahle ngamanyikwe, zonke izimpawu zokuqina ziyaqina.
Nge-hypothyroidism, kuvela isimo lapho kunokwehla kwenani lama-hormone e-thyroid anjenge-thyroxine ne-triiodothyronine, lesi simo siholela ekwehleni kobukhulu bazo zonke izinqubo ze-metabolic.
Ukwehla kwenani lama-hormone e-thyroid, kukhona ukwanda kwenani le-TSH emzimbeni - i-hormone egqugquzela i-thyroid yegland.
I-Hypothyroidism inqubo ekhula kancane kancane. Ukwehla komsebenzi wokusebenza kwe-gland yegilo kubonakala kubantu ngalezi zimpawu ezilandelayo:
- ubuthakathaka bemisipha
- i-arthralgia,
- i-paresthesia
- bradycardia
- angina pectoris
- arrhythmia
- isimo esimbi kakhulu
- ukwehla kokusebenza
- ukwanda kwesisindo somzimba.
I-Hypothyroidism ngesikhathi sokuthuthuka kwayo idala ukuthuthukiswa kokuphazamiseka kokubekezelelana kuma-carbohydrate, okwandisa amathuba okuba umuntu abe nesifo sikashukela sohlobo 2. Ukwenza ngcono isimo nge-carbohydrate metabolism emzimbeni, odokotela batusa ukuthatha umuthi uSiofor, onomphumela we-hypoglycemic.
ISiofor ingeqembu le-Biguanides.
Ubudlelwano obuphakathi kokuphazamiseka emanyeni kanye ne-thyroid gland
Ucwaningo lweziguli ezinokungasebenzi kahle ekusebenzeni kwazo zombili izindlala lukhombisa ukuthi amathuba okukhula kwesifo sikashukela sohlobo 2 akhuphuka kakhulu uma umuntu ehluleka ukusebenza kahle kwe-yegilo yegilo.
Lezi ziguli ziyelulekwa ukuthi zenze izinga le-TSH njalo eminyakeni emi-5. Ukuxhaphaka kwe-hypothyroidism eyinhloko phakathi kwabantu kukhuphuke ku-4%; uhlobo olungatheni lwale nkinga lutholakala ngokwesilinganiso ku-5% wabantu besifazane kanye ne-2-4% yabantu besilisa.
Uma i-hypothyroidism ikhula emzimbeni wesiguli ehlushwa isifo sikashukela, ukuqapha isimo sikashukela kuyinkimbinkimbi. Iqiniso ngukuthi nge-hypothyroidism, indlela glucose edonswa ngayo izinguquko.
Umuthi ofanele kakhulu ukunciphisa inani loshukela emzimbeni nge-hypothyroidism yiSiofor. Endabeni yokuqhubeka kwesifo sikashukela emzimbeni ngokumelene ne-hypothyroidism, isiguli sizwa ukukhathala okungapheli kanye nokwehla komzimba nokuncipha kwe-metabolism.
Ushukela kanye noshukela
Ngokusebenza okujwayelekile kwamanyikwe kanye nezindlala ze-thyroid, okuqukethwe ushukela 1 litre yegazi kuyahluka ngaphakathi kwesimo somzimba. Uma kwenzeka wephulwa, kuguquka isamba senoshukela 1 litre ye-plasma yegazi.
Okuqukethwe kwe-glucose ku-1 l kuya kungazinzi, okuholela ekushintshashintsheni okuphambili kokubili ekuqondeni kokukhuphuka kanye nokwehla kwesibalo se-glucose ku-1 l we-plasma, futhi lokhu kufinyelela ingcindezi ethile kushukela wohlobo 2 sikashukela.
Ukwenza kube ngokwejwayelekile okuqukethwe ama-hormone we-thyroid emzimbeni wesiguli, kusetshenziswa ukwelashwa okufakwa esikhundleni. Ukwelashwa, i-Levothyroxine iyasetshenziswa.
Ukusetshenziswa kwalesi sidakamizwa kunqunywa ngokuhlukile uma izinga le-TSH emzimbeni lisukela ku-5 kuye ku-10 mU / l. futhi T 4 kuyinto ejwayelekile. Omunye umuthi wokwelapha osusele esikhundleni yi-L-thyroxine. Lapho usebenzisa lesi sidakamizwa, kufanele kukhunjulwe ukuthi isikhathi sempilo siphakathi kwezinsuku eziyi-5, futhi ubude besikhathi sezinsuku eziyishumi nambili.
Lapho usebenzisa i-levothyroxine, ukunanela komthamo womuthi kufanele kunqunywe. Ngale njongo, izilinganiso ze-TSH zithathwa njalo emavikini ama-5. Ividiyo ekulesi sihloko izocacisa ubudlelwane obuphakathi kwendlala yegilo kanye nesifo sikashukela.
