IManinil isetshenziselwa uhlobo lwe-2 yesifo sikashukela mellitus (uhlobo oluncike ku-insulin). Umuthi unqunywa lapho ukwanda kokuzivocavoca komzimba, ukwehla kwesisindo nokudla okuqinile kungalethi imiphumela ye-hypoglycemic. Lokhu kusho ukuthi udinga ukuqinisa ushukela wegazi lakho ngeManinil.
Isinqumo ngokuqokwa kwalo muthi senziwa yi-endocrinologist, ngokuya ngokubambelela ngokuqinile ekudleni. Umthamo kumele uhambisane nemiphumela yokunqunywa kwezinga likashukela kumchamo kanye nephrofayili ye-glycemic ejwayelekile.
Ukwelapha kuqala ngemithamo emincane yeManinil, lokhu kubalulekile ikakhulukazi:
- iziguli ngokudla okwanele,
- iziguli ze-asthenic ezinokuhlaselwa kwe-hypoglycemic.
Ekuqaleni kokwelashwa, umthamo uhhafu wethebhulethi ngosuku. Lapho uthatha umuthi, udinga ukubhekisisa njalo amazinga kashukela egazini.
Uma imithamo emincane yesidakamizwa ingakwazanga ukwenza ukulungiswa okudingekayo, khona-ke umuthi uyanda ngokushesha ngaphandle kwesonto noma izinsuku eziningana. Izinyathelo zokwandisa umthamo zilawulwa yi-endocrinologist.
I-Maninil ithathwa ngosuku:
- Izibhebhe ezi-3 zeManinil 5 noma
- Izibhebhe ezi-5 zeManinil 3.5 (zilingana ne-15 mg).
Ukudluliselwa kweziguli kulo muthi kusuka kwezinye izidakamizwa ze-antidiabetic kudinga ukwelashwa okufanayo njengasekubhalweni kwasekuqaleni komuthi.
Okokuqala kudingeka ukhansele umuthi wakudala bese unquma ukuthi yiliphi izinga le-glucose kumchamo nasegazini. Okulandelayo, khetha ukukhetha:
- isigamu sephilisi Maninil 3.5
- isigamu sepilisi yeManinil 5, ngokudla nokuhlolwa kwelebhu.
Uma kuphakama isidingo, isilinganiso somuthi sikhuphuka kancane kancane kuye kwezokwelapha.
Ukusetshenziswa kwezidakamizwa
IManinil ithathwa ekuseni ngaphambi kokudla, igezwa phansi ngengilazi eyodwa yamanzi ahlanzekile. Uma umthamo wansuku zonke ungaphezu kwamathebhulethi amabili womuthi, khona-ke uhlukaniswe nokudla kwasekuseni / kusihlwa, ngokwesilinganiso 2: 1.
Ukufinyelela umphumela ongapheli wokwelapha, kuyadingeka ukusebenzisa umuthi ngesikhathi esichazwe ngokucacile. Uma ngesizathu esithile umuntu engazange awuphuze umuthi, khona-ke kuyadingeka ukunamathisela umthamo ophuthelwe kumthamo olandelayo weManinil.
UManinil isidakamizwa osikhathi saso sokuphatha sinqunywa yi-endocrinologist. Ngesikhathi sokusebenzisa umuthi, kuyadingeka ukuqapha izinga likashukela egazini nomchamo wesiguli masonto onke.
Imiphumela emibi:
- Kusukela ohlangothini lwe-metabolism - hypoglycemia kanye nesisindo sokuthola isisindo.
- Engxenyeni yezitho zombono - ukuphazamiseka kwesimo endaweni yokuhlala nokubona okubukwayo. Njengomthetho, ukubonakaliswa kwenzeka ekuqaleni kokwelashwa. Ukuphazamiseka kuhambe bodwa, akudingi ukwelashwa.
- Ukusuka ohlelweni lokugaya ukudla: ukubonakaliswa kwe-dyspeptic (isicanucanu, ukuhlanza, ukusinda esiswini, izihlalo ezikhathazekile). Imiphumela ayisho ukuhoxa Umuthi bese unyamalala ngokwawo.
- Ukusuka esibindini: ezimweni ezingavamile, ukwanda okuncane kwe-alkaline phosphatase kanye nokudlula kwegazi. Ngohlobo lwe-hyperergic lwe-hepatocyte allergy kulo muthi, i-intrahepatic cholestasis ingakhula, kube nemiphumela esisongela impilo - ukwehluleka kwesibindi.
- Ngasohlangothini lwe-fiber nesikhumba: - imichilo yohlobo lwesikhumba esidalwa ukungabi nalutho nokulunywa. Ukuboniswa kuguqulwa, kepha kwesinye isikhathi kungaholela ekuphazanyisweni okujwayelekile, ngokwesibonelo, ukwethuka komzimba, ngaleyo ndlela kudale usongo empilweni yabantu.
Kwezinye izikhathi ukusabela okujwayelekile kuma-allergia kuyabonakala:
- amakhaza
- izinga lokushisa
- jaundice
- ukubonakala kwamaprotheni emchameni.
IVasculitis (ukuvuvukala kwemithambo ye-allergic) ingaba yingozi. Uma kukhona ukusabela kwesikhumba eManinil, khona-ke kufanele uthintane nodokotela ngokushesha.
- Ukusuka ezinhlelweni ze-lymphatic kanye nokujikeleza kokujikeleza, ama-platelet egazi angancipha ngezinye izikhathi. Kuyaqabukela kakhulu ukuthi kube nokwehla kwenani lezinye izinto zegazi ezakhekile: amangqamuzana abomvu egazi, amaseli amhlophe egazi, nabanye.
Kunezimo lapho zonke izinto ze-cellular zegazi zincishisiwe, kepha ngemuva kokuyeka umuthi, lokhu akuzange kubeke engcupheni impilo yomuntu.
- Kwezinye izitho, ezimweni ezingavamile, lokhu okulandelayo kungabhekwa:
- umphumela omncane wokugaya
- proteinuria
- hyponatremia
- isenzo se-disulfiram-like
- ukungahambelani kahle nezidakamizwa okuyi-hypersensitivity esigulini.
Kukhona imininingwane yokuthi udayi wePonso 4R osetshenziselwa ukudala iManinil yi-allergen futhi imbangela yokubonakaliswa okuningi komzimba kubantu abahlukahlukene.
Ukuxhumana ngomuthi
I-Maninil ayikwazi ukuthathwa nge-hypersensitivity kulo muthi noma izingxenye zawo. Ngaphezu kwalokho, kuphikisiwe:
- abantu abane-allergies kuma-diuretics,
- abantu baguliswa ama-sulfonylureas; derivatives of sulfonamide, sulfonamides, probenecid.
- Akuvunyelwe ukunquma umuthi nge:
- uhlobo lwesifo sikashukela esincike ku-insulin
- ukululeka
- ukwehluleka kwezinso i-3 degrees
- Isifo sikashukela,
- i-pancreatic islet β-cell necrosis,
- metabolic acidosis
- ukwehluleka okukhulu kwesibindi okusebenzayo.
I-Maninil akufanele ithathwe ngabantu abanobudakwa obungapheli. Lapho uphuza utshwala obuningi, umphumela we-hypoglycemic womuthi ungakhuphuka kakhulu noma uvele, okugcwele yizimo eziyingozi esigulini.
Ukwelashwa kwe-Maninil kufakwa ku-contraindication uma kwenzeka kuswelekile i-glucose-6-phosphate dehydrogenase enzyme. Noma, ukwelashwa kufaka isinqumo esinqunyiwe sokubonisana nodokotela, ngoba umuthi ungavusa i-hemolysis yamangqamuzana abomvu egazi.
Ngaphambi kokungenelela okukhulu kwesisu, awukwazi ukuthatha noma yimaphi ama-hypoglycemic agents. Imvamisa phakathi kokuhlinzwa okunjalo kuyadingeka ukulawula amazinga kashukela egazini. Lezi ziguli zinqunywe okwesikhashana imijovo elula ye-insulin.
IManinil ayinakho ukwephulwa okuphelele kokushayela. Kepha, ukuthatha lo muthi kungavusa izimo ze-hypoglycemic, ezizothinta izinga lokunakwa kanye nokuhlushwa. Ngakho-ke, zonke iziguli kufanele zicabange ukuthi zingazithatha yini izingozi ezinjalo.
I-Maninil i-contraindication kwabesifazane abakhulelwe. Akunakudliwa ngesikhathi sokuncelisa kanye ne-lactation.
Ukusebenzisana kweManinil nezinye izidakamizwa
Isiguli, njengomthetho, azizwa indlela ye-hypoglycemia lapho uthatha iManinil nale mithi elandelayo:
- β-blockers
- hlanganisa kabusha
- i-clonidine
- guanethidine.
Ukwehla kweshukela egazini kanye nokwakheka kwesimo se-hypoglycemic kungenzeka ngenxa yokusetshenziswa njalo kwezidakamizwa ezi-laxative kanye nohudo.
Ukusetshenziswa okufanayo kwe-insulin nezinye izidakamizwa ze-antidiabetic kungaholela ku-hypoglycemia futhi kubenamandla esenzo seMananil, kanye:
- Ama-inhibitors e-ACE;
- ama-anabolic steroid;
- antidepressants;
- okususelwa ku-clofibratome, quinolone, coumarin, disopyramidum, fenfluramine, miconazole, PASK, pentoxifylline (lapho kuhanjiswa ngemithamo ephezulu), i-perhexylinoma;
- ukulungiswa kwama-hormone ocansi wesilisa;
- ama-cytostatics weqembu le-cyclophosphamide;
- Ama-ers-blockers, i-disopyramidum, i-miconazole, i-PASK, i-pentoxifylline (ngokuphathwa kwe-intravenous), i-perhexylinoma;
- i-pyrazolone derivatives, phenenecidoma, salicylates, sulfonamidamides,
- ama-tetracycline ama-antibiotics, i-tritokvalinoma.
I-Maninil kanye ne-acetazolamide ingavimbela umphumela wesidakamizwa futhi ibangele i-hypoglycemia. Lokhu kusebenza nasekuphatheni kanyekanye kweManinil kanye:
- β-blockers
- diazoxide
- ama-nicotinates,
- phenytoin
- okokugcoba
- glucagon
- I-GKS,
- ama-barbiturates
- phenothiazines,
- ama-audiathomimetics
- Ama-rifampicin Uhlobo lwama-antibhayidi
- amalungiselelo e-thyroid
- ama-hormone ocansi abesifazane.
Umuthi ungaba buthaka noma uqinise:
- Abaphikisi be-Gastric H2 receptor
- i-ranitidine
- hlanganisa kabusha.
I-Pentamidine kwesinye isikhathi ingaholela ku-hypo- noma i-hyperglycemia. Ngaphezu kwalokho, umphumela wezindlela zeqembu le-coumarin uyakwazi futhi ukuthinta kuzo zombili izinkomba.
Izici zokweqisa
Ukweqisa okwedlulele kweManinil, kanye ne-overdose ngenxa yomphumela wokuqina, kuholela esimweni esiphikelelayo se-hypoglycemia, esihluka ngobude besikhathi nangezifundo, okusongela impilo isiguli.
I-Hypoglycemia ihlala inezimpawu ezibonakalayo zomtholampilo.
Iziguli ezinesifo sikashukela zihlala zizwa i-hypoglycemia isondela. Ukuboniswa okulandelayo kwesimo:
- indlala
- ukuthuthumela
- i-paresthesia
- izibuko
- ukukhathazeka
- indlala yesikhumba
- umsebenzi wokuphazamiseka kwengqondo.
Uma izinyathelo zingathathwanga ngesikhathi, khona-ke umuntu uqala ukukhula ngokushesha kwe-hypoglycemic precoma ne-coma. I-Hypoglycemic coma iyatholakala:
- usebenzisa umlando womndeni
- sisebenzisa imininingwane evela ekuhlolweni kwenhloso,
- usebenzisa ilabhorethri yokuqonda ushukela wegazi.
Izimpawu ezejwayelekile ze-hypoglycemia:
- umswakama, ukunamathela, izinga lokushisa eliphansi lesikhumba,
- ukushaya kwenhliziyo
- kwehliswe noma kufudumele okujwayelekile komzimba.
Ngokuya kobunzima bokwetha, okulandelayo kungavela:
- tonic noma clonic ukweyisa,
- ingqondo
- ukulahlekelwa ukwazi.
Umuntu angakwazi ukwenza ngokuzimela ukwelashwa kwezimo ze-hypoglycemic uma engakafinyeleli ekuthuthukisweni okuyingozi ngendlela ye-precoma ne-coma.
Ukususa zonke izinto ezingezinhle ze-hypoglycemia, isipuni sikashukela esifakwe emanzini noma kwamanye ama-carbohydrate sizosiza. Uma kungekho ukuthuthuka, kufanele ushayele i-ambulensi.
Uma ikhephu landa, khona-ke ukwelashwa kufanele kuqalwe ngokuphathwa kwe-glucose solution ka-40%, 40 ml ngevolumu. Ngemuva kwalokho, kuzodingeka ukwelashwa kokulungiswa kokufaka okune-carbohydrate enesisindo esincane.
Uyacelwa uqaphele ukuthi awukwazi ukufaka isixazululo sikashukela esiyi-5% njengengxenye yokwelashwa kwe-hypoglycemia, ngoba lapha umphumela wokuhlanjululwa kwegazi nomuthi uzokhulunywa ukwedlula ukwelashwa kwe-carbohydrate.
Amacala we-hypoglycemia obambezelekile noma isikhathi eside ayaqoshwa. Lokhu ngokuyinhloko kungenxa yezici ezandayo zeManinil.
Kulezi zimo, ukwelashwa kwesiguli endaweni yokunakekela kakhulu kuyadingeka, futhi okungenani izinsuku eziyi-10. Ukwelashwa kubonakaliswa ukubonwa okuhleliwe kwelebhu kwamazinga kashukela wegazi kanye nokwelashwa okukhethekile, lapho ushukela ungalawulwa usebenzisa, ngokwesibonelo, imitha yokukhetha eyodwa yokuthinta.
Uma umuthi usetshenziswa ngengozi, udinga ukwenza i-gastric lavage, bese unikeza lowo muntu isipuni soshukela noma ushukela.
Ukubuyekezwa mayelana neManinil
Umuthi kufanele usetshenziswe kuphela njengoba kuyalelwe udokotela. Ukubuyekezwa mayelana nokuphuza umuthi kuxubekile. Uma umthamo ungabhekwa, ukudakwa kungenzeka. Kwezinye izimo, imiphumela yokuphuza umuthi kungenzeka ingabonwa.
