Izigameko zomdlavuza we-pancreatic ziyanda minyaka yonke. Odokotela bakuchaza lokhu iqiniso lokuthi umsoco nendlela yokuphila yomuntu wesimanje inezimpawu ezithile nethonya ekwakhekeni kwe-oncology.
Eqinisweni, izimbangela zangempela zamathumba amabi emzimbeni womuntu azikasungulwa.
Ososayensi bazi izinto ezimbalwa nje ezandisa ubungozi bomdlavuza we-pancreatic. Kulesi sihloko, lezi zinto zizocatshangelwa kabanzi.
Ukungondleki
Amathuba okuba nomdlavuza we-pancreatic akhuphuka ngokusetshenziswa kokudla okuningana kokudla kwenyama okunamafutha ezilwane. Kungamafutha ezilwane anomphumela ongemuhle oqinile, ngoba enza ukuthi indlala isebenze ngemodi ethuthukisiwe.
Ngemuva kokudla ukudla okunamafutha, abantu bavame ukuzwa ubuhlungu kumanyikwe. Ukudla okubhemile, okunosawoti ngokweqile noma okubabayo, kanye nemikhiqizo eye yenziwa ekusetshenzisweni kwezobuchwepheshe, kunomthelela ongemuhle, zonke lezi zimbangela nezimpawu kumele zibhekwe futhi zibhekwe.
Ushintsho lwethambo kumangqamuzana endlala lungavela ngokusebenzisa imikhiqizo elandelayo:
- ukudla okusheshayo
- ukudla okusemathinini;
- utshwala
- iziphuzo zekhabhoni;
- amaswidi.
Le mikhiqizo iqukethe izinhlanganisela ze-carcinogenic ezingadala ukwakheka kwamaseli we-atypical, aguqulwa kamuva aguqulwa aba ngamathumba amlimazayo nomdlavuza.
Kubalulekile ukwazi ukuthi ngaphansi kwethonya lotshwala kukhona ukwanda komsebenzi wezimfihlo wamanyikwe!
Ama-hormone akhiqizwayo ahlala ngaphakathi emzimbeni futhi abamba iqhaza ezinqubweni ze-pathological ezenzeka epithelium. Ngokuvamile, i-pancreatitis engapheli iba lapho uphuza utshwala, kepha udinga ukukhumbula ukuthi lesi simo sinengqondo, futhi izinga elilandelayo lokukhula kwalo ngumdlavuza.
Ukudla okuhle, inani elikhulu lezithelo nemifino kunciphisa ubungozi bomdlavuza we-pancreatic. Indima ebaluleke kakhulu idlalwa ngokudla. Uma uhlala udla ngokweqile futhi udla inani elikhulu lokudla ngasikhathi sinye, lokhu kudala umthwalo omkhulu ku-gland, kuyilapho ukondleka okunezihlakala kwakha umbuso ofanele wesitho.
Umphumela omuhle ekusebenzeni kwe-pancreatic, i-lycopene ne-selenium - lezi zingxube ezitholakala kwimifino ebomvu nephuzi
Ukubhema
Kwabhemayo abanolwazi olude, ubungozi bokuthola umdlavuza we-pancreatic uphakeme kakhulu. Intuthu kagwayi e-inhaled iqukethe ama-carcinogens amaningi, okuholela ekwakhekeni kwamaseli we-atypical emzimbeni womuntu.
Ama-polycyclic aromatic hydrocarbons (PAHs) ayingozi kakhulu endabeni. Bayakwazi ukuvusa izinqubo zesimila kuzo zonke izicubu zomzimba. Ukubhema kubuye kuholele ekubambeni imbobo ye-bile yamanyikwe. Lokhu kubangela ushintsho lwe-pathological esitholeni futhi kungavusa izifo ezingapheli, bese kuba nomdlavuza. Ngemininingwane eminingi yokuthi ukubhema kubangelwa yini i-pancreatitis, ungafunda kwiwebhusayithi yethu.
Kuyaziwa ukuthi umdlavuza we-pancreatic wenzeka kubantu ababhemayo cishe amahlandla amathathu kaningi kunabantu ababhemayo. Kepha leli thonya liyaphenduka futhi uma wenqaba ukubhema iminyaka eminingana, isimo sizinza.
Izimbangela lapha zisemihleni, futhi uma ungathathi zinyathelo zokuyeka imikhuba emibi, umdlavuza ungaba ukuqhubeka komqondo kokubhema.
Isisulu sokuqothuka
Cishe i-10% yamacala omdlavuza we-pancreatic, amanye amalungu omndeni abenesifo esifanayo. Uma isihlobo (izingane zakwethu, abazali) besinokuxilongwa okunjalo, ubungozi bukhuphuka nangaphezulu.
Isici esinjalo ekwakhiweni kwe-neoplasms ebulalayo ye-gland ihlotshaniswa nezakhi zofuzo eziningana. Kepha kuze kube manje ngeke ithole isayithi elithile ku-chain yazo elibhekele le nqubo.
Isifo sikashukela mellitus
Ingozi yamathumba amabi ikhuphuka kakhulu phambi kwesifo sikashukela. Izizathu lapha bezaziwa kudala - ukwakheka okunganele kwe-insulin kubangela i-hyperglycemia (ukwanda okuqhubekayo kokuxineka kweglucose egazini), okuphazamisa ukusebenza komzimba wonke.
Njengomthetho, phakathi kwalezi zifo kunokuxhuma kwezindlela ezimbili. Kusukela ukukhiqizwa kwe-insulin kwenzeka kumanyikwe, ukungasebenzi kwesitho kungadala ukwanda kwesifo sikashukela.
Ezinye izimbangela ze-oncology
I-pancreatitis engapheli iholela ezinqubweni zesikhathi eside zokuvuvukala kumanyikwe, okuandisa amathuba okuguqulwa okungafanele kwezakhiwo zeseli. Uma lesi sifo singalashwa ngesikhathi noma kusenziwa ukwelashwa okungafundile, ngokushesha kuzovela izinkinga, phakathi kwalokho okungase kube nokuqubuka okulimazayo.
Njengoba i-pancreatitis iholela ekuqineni okuqhubekayo kwama-pancreatic ducts, imfihlo eyakhiwa yilesi sitho iqala ukuqina. I-carcinogenic compounds ingahle ibe khona ku-fluid, umphumela owenzeka isikhathi eside lapho epithelium yesitho ingaholela ekwakhekeni kwamangqamuzana amabi.
Ingozi enkulu ngokuya ngokuguqulwa ibe isimila esinomdlavuza yi-pancreatic adenoma. Kuqala, inomlingiswa ongajwayelekile, kepha kwesinye isikhathi ubungozi bayo bungenzeka (ukuguqukela kwifomu elimazayo).
Kunohlobo lwesimila oluphakathi nendawo, oluthi, ngokusho kwabanye ososayensi, lomdlavuza wesifo esiphansi. Uma i-adenoma ye-gland isuswa ngokushesha ngokuhlinzwa, ingozi yokuthola umdlavuza ayifakwa ngokuzenzakalelayo.
I-cirrhosis yesibindi nayo ingaholela ezingqubuzaneni ezinesihlungu zamanyikwe. Kulesi simo, kwenzeka izinguquko ze-pathological ezicutshini zesibindi futhi kudalwa izinto ezinobuthi ezingena kumanyikwe ngamadayi we-bile.
Ukukhuluphala nokungasebenzi ngokomzimba
Izizathu lapha ukuthi kunokuntuleka kokuhamba nokukhuluphala ngokweqile, kungaholela ekwakhekeni kwezimila ezinomdlavuza. Ukuhlolwa kwabantu abanenkomba yokwenyuka kwesisindo somzimba kukhombisa ukuthi banezinguquko ekwakhiweni kwamanyikwe, okungenzeka ngaphansi kwezimo ezithile kudale umdlavuza.
Ngasikhathi sinye, ukuxilongwa kwabantu abanesisindo esijwayelekile, abazivocavoca njalo futhi bephila ngendlela efanele, kukhombisa ukuthi amanyikwe asesimweni esizinzile futhi azinazimpawu zokuthuthuka kwezifo.
Isifo sokuqaqamba kokulimala okulimazayo kwe-pancreas kunqunywa yisigaba sesifo, iminyaka yesiguli nokuba khona kwezifo ezihlangene.
Ithonya lobudala kanye nobuzwe
Ingozi yomdlavuza we-pancreatic inyuka ngeminyaka. Imvamisa, ukutholakala okunje kwenziwa kubantu abaneminyaka engaphezu kwengu-45. Cishe i-90% yeziguli ezinama-glandular tumors zingaphezulu kweminyaka engamashumi amahlanu nanhlanu. Kepha iminyaka yobudala ayisiba yisithiyo ekuthuthukisweni komdlavuza ngenxa yezici ezithile zobungozi.
Ngokuqondene nobuzwe ezigulini, umdlavuza we-pancreatic uvame ukutholakala kubantu abamnyama kunase-Asia nasebelungu.
Izifo ze-oncological ze-pancreas zingenzeka ngesikhathi somsebenzi wezimboni eziyingozi, ngokuxhumana njalo nezinto ezinobuthi. Akhiwa, ngokwesibonelo, ngesikhathi sokufakwa kukawoyela noma ngamalahle wamalahle.
Kubalulekile ukwazi ukuthi izici zobungozi azizona izimbangela eziqondile zomdlavuza we-pancreatic. Abanye abantu bangaba nazo zonke izici zobungozi, kepha ngeke bawuthole umdlavuza. Ngaso leso sikhathi, lesi sifo singathinta abanye abantu, noma ngabe kungekho zidingo zaso.
Izimpawu eziphambili zomdlavuza we-pancreatic
Isigaba sokuqala salesi sifo singakhombisa izimpawu ezahlukahlukene. Njengomthetho, izimpawu nezimpawu zomdlavuza we-pancreatic zingacacile futhi azinakho ukucaciswa, ngakho-ke umuntu angahle angabaphenduli futhi angasoli ngalesi sifo.
Umdlavuza we-pancreatic ungakhula kancane, iminyaka eminingana, ngaphambi kokuba izimpawu ezithile ziqale ukuvela, okubonisa kahle lokhu i-pathology. Ngalesi sizathu, ukutholakala kwalesi sifo kuzo zombili iziguli nodokotela kunzima impela.
Kunezimpawu ezithile ezihlotshaniswa nomdlavuza we-pancreatic, kepha imvamisa azinakho ukucaciswa futhi zivame ukubangelwa ezinye izinqubo. Uphawu oluphambili yi-jaundice. Kwenzeka lapho i-bile duct ivinjiwe bese i-bile ingena egazini.
Ezigulini ezine-jaundice, umchamo umnyama, kunesitofu sobumba esingaxinekile, isikhumba sibe mnyama, amehlo aphuzi. Ngenxa ye-bilirubin ephezulu, kungenzeka kuvele isikhumba esikhanyayo.
Imvamisa, i-jaundice ivela ngenxa yesifo se-gallstone, kepha kwesinye isikhathi ukubukeka kwayo kungabanga nomdlavuza wekhanda we-pancreatic. IJaundice ehambisana nokwakhiwa kwama-gallstones imvamisa ihambisana nobuhlungu obukhulu. Umdlavuza wepancreatic ubonakala ngokuthi "i-jaundice engenabuhlungu."
Ngaphezu kwalokho, iziguli ezinomdlavuza we-pancreatic zivame ukuba nezinkinga ngohlelo lokugaya ukudla, futhi izimpawu zimi ngokulandelayo:
- isicanucanu
- ukuqunjelwa
- isifiso sokudla;
- ukunciphisa umzimba;
- isifo sohudo
Lezi zimpawu zidalwa ukwakheka okuqondile kwesimila endaweni yokugaya ukudla noma ukungena kwezinzwa. Uma ipheshana lesisu livinjelwe isimila, isiguli sizwa isicanucanu nobuhlungu, sibi kakhulu ngemuva kokudla.
Isibonakaliso esibonakalayo somdlavuza we-pancreatic ukuqoqwa kwenqwaba yamamanzi emzimbeni wesisu. Lesi simo sibizwa ngokuthi ama-ascites. Izizathu ezimbili eziyinhloko zinegalelo ekukhuleni kwayo:
- Kukhona ukuvaleka kokudonsa kwegazi kusuka emathunjini kuya esibindini ngokusakazeka kwalesi sifo. Ngenxa yalokhu, uketshezi lugelezela emgodini wesisu.
- Ukusakazeka kwesigaxa se-pancreatic emgodini wesisu.
Uketshezi lunganqwabelana ngamanani amakhulu kakhulu luze lube nomthelela ekuphefumuleni, lukwenze kube nzima. Kwezinye izimo, inqubo ingahle ilungiswe ngosizo lokwelashwa ngezidakamizwa (kuchazwa ama-diuretics). Kwesinye isikhathi iziguli zidinga i-paracentesis (drainage drainage).
Ukuqagela kwalesi sifo.
Umdlavuza we-pancreatic ungenye yezinhlobo ezinkulu zomdlavuza. Kepha, ngokusho kochwepheshe abaningi, ngokuxilongwa okufika ngesikhathi kanye nokwelashwa okunekhono, ukugula kuyelapheka impela.
