I-Hypofunction kanye ne-hyperfunction ye-pancreas kuhlobene kakhulu nokwenzeka nokuthuthuka kwe-pathologies kwezicubu zesitho.
Imvamisa, i-hypofunction iyakhula, kepha kwezinye izimo, umsebenzi wamaseli wezinhlaka uyanda. Lesi simo siholela ekutheni isiguli siveze ukuqina kwamanyikwe. Ukwephulwa okunjalo kwenzeka kakhulu kakhulu futhi, njengomthetho, kuhambisana nokuqhubeka kwezifo ezimbi emzimbeni.
Ngokuyisisekelo, i-organ hyperfunction izibonakalisa kokuqukethwe okwandisiwe kwe-insulin egazini.
Izimbangela zokwanda kokusebenza kwamaseli
Izizathu ezidala ukwanda komsebenzi kwamaseli we-pancreatic glandular kungenzeka zingahambisani nokuphazamiseka ekusebenzeni kwesitho.
Ukwanda komsebenzi wezicubu ze-glandular kungabangelwa ukwelashwa okungalungile noma okunganele kwesifo sikashukela lapho i-insulin ethe xaxa ifakwa endaweni yangaphakathi yomzimba kunalokho okudingekayo ngenqubo yokulungiswa.
Lesi simo senzeka lapho ukubalwa komthamo wezidakamizwa kungalungile noma ngemuva kokuphathwa kwezidakamizwa esiswini esingenalutho.
Ngaphezu kwalokho, imbangela yokwanda komsebenzi wezimfihlo kungaba ukuthuthukiswa kwe-insuloma.
I-insuloma ukwakheka kwesimila esikhula esiqhingini saseLangerhans. I-neoplasm enjalo izicubu ze-pancreatic iholela ekukhiqizweni okwandayo kwe-insulin. Isimila esinjalo singekho emthethweni futhi asenzi ama-metastases, kepha umphumela we-pancreatic hyperfunction uholela ekukhuleni kwezinkinga ezinzima emzimbeni ezingadala ukulimala okukhulu emzimbeni ekubeni kungekho ukwelashwa okwanele.
Ukwakheka kwezinhlobo ezithile zamathumbu ebuchosheni nakho kuholela ekwandeni komsebenzi wezimfihlo wamaseli.
Izimpawu izici zesimo se-pathological of gland
Yiziphi izimpawu ezibonakala ngokusebenza okwengeziwe kwezomfihlo, futhi kwenzekani nge-hypofunction yamanyikwe?
Ukubonakala kwezimpawu zokubonisa umsebenzi owandayo wamaseli we-pancreatic kuhlotshaniswa nokuqala kanye nokuqhubeka kwe-hypoglycemia emzimbeni wesiguli.
I-Hypoglycemia iyisibonakaliso esiyinhloko se-secretory hyperacaction of izicubu zesitho.
Izimpawu ezivezwa yilesi simo se-pathological ngesikhathi sokwanda kokwephulwa yilezi zimpawu ezilandelayo:
- Ekuseni, kunzima ukuthi isiguli sizulazule, kaningi ngalezo zikhathi siphinda ukunyakaza namagama afanayo, futhi singaphendula ngokungahleliwe kwimibuzo ebuzwe.
- Ukuphazamiseka kwe-Psychomotor kuyabonakala, isiguli kwesinye isikhathi asizitholi indawo, lokhu kuvame ukuholela abanye emcabangweni wokuthi umuntu udakiwe.
- Isiguli singabanjwa ukufana okufana nokubukeka kwesithuthwane, kepha kuhlala isikhathi eside.
- Umuntu unokukhuphuka kokujuluka, kukhona ukweqa okubukhali kwengcindezi yegazi, futhi isigqi sokuqina kwenhliziyo singaphazamiseka.
- Ukuqhubeka kwe-hypoglycemia kuholela ekuqwashisweni okungasebenzi kahle, kuze kufike kumuntu owela ekhefini le-hypoglycemic.
Phakathi kwezikhathi zokwanda kumuntu, kutholakala izimpawu ze-hypoglycemia engapheli:
- ukulimala kwe-nuclei yesibindi ne-glossopharyngeal nerve, futhi ngenxa yalokho, ukulimaza kukhuthaza ukukhubazeka kwemisipha yobuso;
- ukuphazamiseka kuma-tendon reflexes kanye nokuvela kwe-patreflexes;
- kukhona ukwehla kwenkumbulo nokusebenza kwengqondo.
Izimpawu zomsebenzi ocashile wokuncishiswa kuncike ezimweni zodwa zomzimba wesiguli.
Izimpawu eziyisisekelo zokwephulwa okunjalo yilezi:
- Ukomisa.
- Umuzwa omile emlonyeni.
- Ukhuphula ukuchama.
- Ukwehla kwesisindo okusheshayo
- Ukuvela kwemizwa yokucanuzelelwa kwenhliziyo kanye nesifiso sokuhlanza.
- Ukubonakala kobuhlungu kusendaweni.
- Ukubonakala kokudideka.
- Ukuvela kokukhathala kanye nokwehla okujwayelekile.
Lezi zimpawu zingaba yizihibe zokuqala nokwanda kwesiguli esinesifo sikashukela.
Ukuphazamiseka komsebenzi wezimfihlo kwenzeka kwizicubu ze-pancreatic kaningi ngenxa yesikhumba.
Ukwephulwa kwemisebenzi ye-intracecretory kuvame ukuhambisana nokuphulwa komsebenzi we-procrine wezicubu ze-glandular, okuhambisana nokuphulwa ekusebenzeni kwendlela yokugaya ukudla.
Izindlela zokuxilonga zomsebenzi we-hypersecretory
Ukubona ubukhona bokukhuphuka okwengeziwe, kusetshenziswa izindlela ezahlukahlukene zokuxilongwa kwe-pathology. Okokuqala, kuhlaziywa izikhalazo zesiguli kanye nomlando wezokwelapha.
Ngemuva kokuthola ulwazi oluyinhloko, udokotela obonayo unquma izindlela ezikhethekile zokuxilonga. Ekuhlolweni, zombili izindlela ezisetshenziswayo zocwaningo lwelebhu nezisetshenziswa.
Njengoba kusetshenziswa izindlela zaselebhu:
- ukuzimisela kwenani likashukela emzimbeni esiswini esingenalutho;
- ukunqunywa kwenani le-insulini ku-plasma yegazi; ngale njongo kusetshenziswa enye yezindlela ezifundisayo - i-radioimmunological;
- ukuhlolwa kwegazi ushukela onomthwalo;
- ukuzimisela kwe-proinsulin ne-C-peptide egazini;
- ukwenza izivivinyo ezisebenzayo ngokuzila ukudla.
Njengezindlela ezisizayo zokuxilonga ukwanda komsebenzi we-pancreatic cell, kusetshenziswa okulandelayo:
- I-Tomography ehlanganisiwe.
- I-Angiography.
- Ukuxilongwa kwethambo le-portal ukuthola i-insulin engasebenzi.
Ngemuva kokwenza lonke ucwaningo oludingekayo nokuqinisekisa ukutholakala kwesifo, udokotela obonayo unquma inkambo yokwelashwa okuhloswe ngayo ukuthi i-pancreas ijwayeleke ukwenziwa kube yiyona.
Ukuzikhethela kwendlela yokwelashwa kuya ngezinga lokuthuthuka kwenqubo ye-pathological kanye nohlobo lwayo.
Izindlela zokwelapha ezisebenza ngokweqile
Ukwelapha kwesimo se-gland hyperfunction esikhathini esibuhlungu kuqukethe ukwethulwa kwekhambi le-glucose ngaphakathi emzimbeni.
Ukwelashwa kokuthola ukuba khona kwe-insulinomas kwezicubu ze-gland kubandakanya ukungenelela kokuhlinzwa. Ukuhlinzwa kususa isimila. Uma kwenzeka kwembulwa isimo esibuhlungu sokugxila kwe-tumor, isuswa ngengxenye yezicubu ze-gland.
Uma ukuhlinzwa kungenakwenziwa ngezizathu ezinengqondo, isiguli sinqunywe inkambo yokwelashwa, equkethe izidakamizwa ezicindezela ukwakheka kwe-insulin ye-hormone.
Lapho ukhomba isifo seziguli, ukunamathela ekudleni okhethekile kubaluleke kakhulu. Ukudla okunjalo kufaka phakathi ukusetshenziswa kokudla okune-carbohydrate eningi.
Ukuhambisana nokudla kokudla kusho ukwenqatshelwa kokusetshenziswa kwamafutha nokudla okunezipayisi, ngaphezu kwalokho, isiguli kufanele senqabe ukusebenzisa imikhiqizo kafulawa ekudleni.
Endabeni yokwanda okwenziwa imfihlo yezicubu ze-pancreatic, izinga likashukela ne-insulin egazini kufanele lilawulwe, futhi esimweni sokwehla kwenani lama-carbohydrate, kuyadingeka ukwandisa okuqukethwe kwabo ngokudla ukudla okuqukethe inani elikhulu lale ngxenye.
Ukusebenzisa lolu hlobo lokudla kungakhuphula ushukela wegazi lakho futhi kwehlise namazinga akho e-insulin.
Imisebenzi yamanyikwe ichazwe kuvidiyo kule ndatshana.
