Kunezinkomba eziqondile zokusebenzisa umuthi we-insulin Actrapid MK. Lokhu kufaka phakathi:
- thayipha i-1 isifo sikashukela (i-insulin encike);
- Uhlobo 2 isifo sikashukela mellitus (ukumelana ne-insulin).
Uma sicabanga ngecala lesibili, lapho-ke sikhuluma ngokumelana okuphelele nokuyingxenye kwalezo zidakamizwa ezilwa ne-glycemic okumele ziphuzwe ngomlomo. Ngaphezu kwalokho, i-Actrapid inganconywa ngesikhathi sokukhulelwa nezifo ezihlobene noshukela.
Kunezinto ezithile esikhundleni se-insulin Actrapid MK, kepha ukusetshenziswa kwazo kumele kuvunyelwane nodokotela oholayo. Lezi zihlanganisi zifaka: i-Actrapid MS, iMaxirapid BO-S, i-Iletin II ejwayelekile, kanye neBetasint engathathi hlangothi i-E-40.
Isithako esisebenzayo kulo muthi si-soluble pork insulin esifushane, futhi i-Actrapid yenziwa ngendlela yesisombululo somjovo.
Umuthi uphekelwa umthetho uma kwenzeka kwenzeka kuyi-hypersensitivity kuwo, kanye ne-hypoglycemia.
Ungasifaka kanjani isicelo futhi uphuze?
Ama-Actrapid kufanele aphathwe:
- ngokuzithoba;
- intramuscularly;
- ngomzimba.
Ukuphathwa kwe-subcutaneous kungenziwa esifundeni sowesifazane. Yile ndawo evumela ukuthi umuthi udakwe kancane futhi ngokulinganayo. Le ndlela yokulawulwa kwezidakamizwa ingenziwa ku-buttock, izicubu zomsipha wehlombe noma odongeni lwesisu sangasemuva.
Umthamo we-Actrapid kufanele unqunywe ngudokotela ohambelayo. Lokhu kwenzeka ngakunye ngokusekelwe ecaleni elithile lalesi sifo kanye noshukela wegazi lesiguli. Uma sikhuluma nge-avareji ejwayelekile yansuku zonke, khona-ke izosuka ku-0,5 iye ku-1 IU ngekhilogremu yesisindo somzimba wesiguli.
I-insulin ikhishwa isigamu sehora ngaphambi kokudla okuhlosiwe, okuzoba nama-carbohydrate. Izinga lokushisa lomuthi lingukushisa kwekamelo.
Umjovo wenziwa esibayeni sesikhumba, okuba yisiqinisekiso sokuthi inaliti ayingeni emsipha. Isikhathi ngasinye esilandelayo, amasayithi womjovo kufanele aguqulwe. Lokhu kuzosiza ukuqeda amathuba okukhula kwe-lipodystrophy.
Ukwethulwa kwe-Actrapid intramuscularly andralylyly kuhlinzeka ngokulawulwa okuphoqelekile kodokotela. I-insulin emfushane imvamisa isetshenziswa ngokubambisana ne-insulin yemiphumela ephakathi noma yesikhathi eside emzimbeni wesifo sikashukela.
Umphumela oyinhloko wesidakamizwa
I-Actrapid MK isho izidakamizwa ze-hypoglycemic. Le insulin esebenza kancane. Ihlangana ne-receptor ekhethekile ye-membrane engaphandle yolwelwesi lweseli futhi ngaleyo ndlela idale inkimbinkimbi yonke ye-insulin-receptor.
Ukwehla kweshukela egazini kungabangelwa:
- ukukhula kwezokuhamba kwayo okuyinqayizivele;
- ukumuncwa okwandayo kanye ukumuncwa kwezinto ngezicubu;
- ukukhuthaza kwe-lipogenesis, i-glycogeneis;
- synthesis amaprotheni;
- ukwehla kwezinga lokukhiqizwa koshukela isibindi.
Isikhathi sokuvezwa kwe-Actrapid emzimbeni sizonqunywa ngokuphelele ngezinga lokufakwa. Lokhu kokugcina kuzoncika ezicini eziningana ngasikhathi sinye:
- umthamo
- indlela yokuphatha;
- izindawo zokungena.
Ngemuva kokuphathwa kwe-subcutaneous, umphumela uvela ngemuva kwemizuzu engama-30, ukuqoqwa okuphezulu kwe-insulin emfushane kwenzeka ngemuva kwamahora ama-1-3, futhi ubude besikhathi sokuvezwa kungamahora ayi-8.
Imiphumela emibi ngemuva kokusebenzisa i-Actrapid
Kwasekuqaleni kokuqala kokwelashwa, ukugqwala kwezinga eliphezulu nelingaphansi, kanye nombono ongenakukhubazeka, kuyabonakala. Okunye ukusabela okungalungile kungenzeka uma:
- ukuphathwa okusheshayo komthamo omkhulu we-insulin;
- ukungahambisani nokudla (isibonelo, ukweqa ibhulakufesi);
- ukuzikhandla ngokweqile komzimba.
Zizokhonjiswa ngokubonakaliswa kwe-hypoglycemia: ukujuluka okubandayo, ukushwabana kwesikhumba, ukwethuka ngokweqile, ukwethuka kwemikhawulo, ukukhathala okushesha kakhulu, ubuthakathaka, kanye nokuphazamiseka kokukhumbula umzimba.
Ngaphezu kwalokho, imiphumela emibi ingabonakaliswa ikhanda elibuhlungu, isiyezi, isicanucanu, i-tachycardia, izinkinga zokubuka kwesikhashana, kanye nomuzwa ongathandeki wendlala.
Ezimweni ezinzima ikakhulukazi, ukulahleka kwengqondo noma ukukhubazeka kungenzeka.
Ukubonakaliswa kwe-allergic system nakho kungabukwa:
- ukujuluka ngokweqile;
- ukuhlanza
- ukuphefumula okuyinkimbinkimbi;
- ukuzindla kwenhliziyo;
- isiyezi.
Kukhona amathuba okusabela kwasendaweni:
- ubomvu
- ukulunywa kwesikhumba;
- ukuvuvukala.
Uma bekunemijovo ejwayelekile kakhulu endaweni efanayo, i-lipodystrophy ingakhula.
Izimpawu ze-overdose
Ngemithamo ebalulekile ye-Actrapid, i-hypoglycemia ingaqala. Ungaqedwa uma ushukela noma ama-carbohydrate athathwa ngomlomo.
Ezimweni ezinzima kakhulu zokulahlekelwa ukwazi, kunikezwa ukuphathwa kwe-intravenous kwesisombululo se-dextrose samaphesenti angama-40, kanye nanoma iyiphi indlela yokulawulwa kwe-glucagon. Ngemuva kokuzinza, kunconywa ukudla okuqukethe ama-carbohydrate amaningi.
Imiyalo esemqoka yokusetshenziswa kwe-Actrapid
Ngesikhathi sokulashwa nalesi sidakamizwa, kubalulekile ukuthi ubheke njalo ushukela egazini. Lokhu kuyiqiniso ikakhulukazi lapho i-Actrapid ifakiwe kuzixazululo zokufaka.
Ngaphezu kwe-overdose, imbangela yokuqalwa kwe-hypoglycemia kungaba:
- ukuguqulwa kwezidakamizwa;
- ukweqa ukudla;
- ukuhlanza
- ukweqisa kwemvelo ngokomzimba;
- ukuguqulwa kwesayithi lomjovo.
Uma i-insulin ingakhishwa ngendlela efanele noma kukhona ikhefu okusetshenziswayo, lokhu kungavusa i-hyperglycemia noma isifo sikashukela sikashukela.
Ekubonakalisweni kokuqala kwe-hyperglycemia, ukuhlaselwa ukoma, isicanucanu, ukwanda kokuchama, ubomvu kwesikhumba kanye nokuphelelwa isifiso sokudla kungaqala. Uma ukhipha, kuzoba nomqondo ocacile wephunga le-acetone, ngaphezu kwalokho, i-acetone ingahle ichaphazele umchamo, futhi lokhu sekuyisibonakaliso sesifo sikashukela.
Uma ukukhulelwa kuhlelwa, kusadingeka ukwelapha ukubonakaliswa kanye nezimbangela zesifo sikashukela. Kulesi sikhathi esibalulekile emzimbeni wowesifazane, isidingo se-insulin siyancipha, ikakhulukazi ku-trimester yakhe yokuqala. Ngaphezu kwalokho, njengoba isikhathi sikhula, umzimba uzodinga i-insulin ethe xaxa, ikakhulukazi ngasekupheleni kokukhulelwa.
Ngesikhathi sokuzalwa kwengane noma ngaphambi kwalolu suku, isidingo se-insulin eyengeziwe kungenzeka singasebenzi noma simane sehlise kakhulu. Lapho nje kuzalwa, owesifazana uzodinga ukuzijova inani elifanayo le-hormone njengaphambi kokukhulelwa.
Ngesikhathi sokuqunjelwa, kungahle kube nesidingo sokunciphisa umthamo we-insulin futhi ngenxa yalesi sizathu kubalulekile ukuqapha ngokucophelela isimo somzimba wakho futhi ungaphuthelwa isikhathi lapho ukuqina kwezidingo ze-insulin kuza.
Ungagcina kanjani?
I-Actrapid MK kumele ivikelwe ngokucophelela elangeni, gwema ukushisa ngokweqile, ukuboniswa ukukhanya, kanye ne-hypothermia.
Awungeke usebenzise umuthi uma wawuneqhwa noma ulahlekelwe ukungabi namabala kwawo nobala.
Ngesikhathi sokulashwa, izinyathelo zokuqapha kumele zithathwe lapho ushayela izimoto nezinye izinto ezingaba yingozi eziyingozi. Umsebenzi obandakanya ukunakwa kakhulu ukunakwa, kanye nesivinini sokuphendula kwengqondo, akwamukeleki ngenkathi uthatha i-Actrapid. Lokhu kungenxa yokuthi ngesikhathi se-hypoglycemia izinga lokuphendula lingancishiswa kakhulu.
Ukuxhumana nezinye izidakamizwa
Kukhona ama-ejenti we-hypoglycemic angavumelani ngokwezokwelapha nezinye izixazululo. Umphumela we-Hypoglycemic ungathuthukiswa ngama-sulfonamides, ama-inhibitors we-MAO, ama-inhibitors we-carbonic anhydrase, ama-ACE inhibitors, ama-anabolic steroid, ama-androgens, ama-bromocreptin, i-tetracycline, ama-clofibrate, i-ketonazole, i-pyridoxine, i-quinine, i-chitin, i-phenylomine, phenolomine.
Umphumela we-Hypoglycemic ungancipha yimithi enjalo:
- i-glucagon;
- izindlela zokuvimbela inzalo ngomlomo;
- i-octreotide;
- reserpine;
- i-thiazide noma i-loop diuretics;
- abamelene ne-calcium;
- i-nicotine;
- insangu
- Ama-blockers e-H1-histamine receptor;
- i-morphine;
- diazoxide;
- ama-anticepressants ama-tricyclic;
- i-clonidine.
Ukuthuthukisa noma ukwenza buthaka kakhulu umphumela we-hypoglycemic we-insulin kungaba yi-pentademin, kanye ne-beta-blockers.
Imininingwane eqondile emayelana nezimpawu zokusebenzisa, izindlela zokusebenzisa nokuzigcina zingatshela udokotela kuphela.