Ukulungiswa kwe-insulin ye-Lantus yokuqinisa ushukela

ILantus ingenye ye-insulin esanda kwethulwa emakethe yasekhaya. Leli thuluzi lihluke kakhulu kwezinye izidakamizwa, liwukuphela kwe-analogue ye-insulin yabantu. Yini iLantus, ukuthi ungayisebenzisa kanjani futhi uyiqede, nokunye okuningi, uzofunda endabeni yanamuhla.

Ngabe iLantus isetshenziselwa ini?

Isithako esikhulu esisebenzayo eLantus yi-insulin glargine. Enye yezinzuzo ezibaluleke kakhulu zalesi sidakamizwa ukuthi ayinayo imisebenzi ephezulu kakhulu futhi inephrofayili yesenzo esibushelelezi. Leli khambi linomphumela owenzeka isikhathi eside (yi-insulin ende), libopha okungcono kuma-receptors ane-insulin futhi lenza ama-metabolites ambalwa kune-insulin yemvelo yomuntu.

I-glycemia egcinwe ezigulini ibonwa ngemuva kwezinsuku ezingama-3-6 zokwelashwa neLantus. Ingxenye yempilo yayo iyefana neye-insulin yemvelo. I-metabolabolization kanye nesenzo somuthi uqobo singacindezela izidakamizwa ngama-corticosteroids, i-danazol, i-glucagon, ama-estrogens, ama-progestin, ama-hormone okukhula, ama-protease inhibitors nama-hormone e-thyroid.

Uma uthatha le mithi, ungadinga ukulungiswa komthamo.

Ukufakwa kwalomuthi kubekelwe iziguli ezinesifo sikashukela:

1. Ukuqiniswa kokuqina kwe-glucose egazini phakathi nosuku (ikakhulukazi ekuseni);
2. Ukuvimbela ukuhanjiswa kwesifo sikashukela sohlobo 2 kuye 1;
3. Ukuvikela ama-pancreas ngesifo sohlobo 1 nokugcina okungenani amaseli athile we-beta anempilo;
4. Ukuvimbela i-ketoacidosis yesifo sikashukela.

Imijovo enjalo ihlehlisa kakhulu amanyikwe. Le insulin esebenza isikhathi eside isiza ukunciphisa ama-spikes emazingeni kashukela.
Ama-insulin amade awalungele izinhloso ezifanayo nezifushane. Ngeke bakwazi ukucisha masishane ushukela omningi ngemuva kokudla. Futhi, imali enjalo ayilungele lezo zinhloso lapho udinga ukwehlisa ngokushesha ushukela.

Uma usebenzisa izidakamizwa ezinjengeLantus ngale nhloso, umphumela wokusebenzisa ngeke ube muhle kuphela, kuzoba yimbi. Ebantwini, ukugxumagxila ekuhlolweni kwe-glucose kuzohlala kwenzeka, ukukhathala kuzokwanda futhi kuthi izifundazwe ezicindezelayo zenzeke, izinqubo ze-metabolic zizophazamiseka. Ngokuhamba kweminyaka eyi-1-3, izinkinga zizoqala ukuvela, ngenxa yokuthi isiguli singakhubazeka.

Ngabe isebenza kanjani i-insulin isikhathi eside?

Lolu hlobo lwesidakamizwa esine-insulin luyafakwa ukuze kulondolozwe ukuqina okujwayelekile kweglucose egazini. I-insulin encane ihlala itholakala futhi ijikeleza egazini lomuntu, into eyaziwa ngokuthi yi-basal noma i-insulin level.

Le insulin ihlinzekwa ngamanyikwe ngokuqhubekayo. Lapho umuntu edla okunye ukudla, le ndlala isheshe iphenduke futhi ikhiphe ngisho ne-protein eyengeziwe egazini. Le nqubo ibizwa ngokuthi i-bolus noma i-bolus.

Imithamo yeBolus ivame ukukhuphula amazinga e-insulin isikhathi esifushane. Ngakho-ke, ushukela, ongena emzimbeni womuntu ngokudla, awuthathi hlangothi. Lapho umuntu egula isifo sikashukela, akakhiqizi i-bolus kanye nama-insal insulin.

Ukukhetha umthamo

Umthamo weLantus ekuseni nasebusuku ungahluka. Ngakho-ke, kubalulekile ukubala umthamo walezi zindlela ngokwehlukana.

Dosa ebusuku

Kubalulekile ukuthi ngemuva kokujova izinga loshukela wegazi ligcinwe ku-4.5-0.6 mmol / litre yegazi. Ngohlobo 1 sikashukela, udinga ukujova i-insulin ende ngaphambi kokulala nangemva kokulala, okufushane noma kwe-ultrashort ngaphambi kokudla. Kuvela cishe imijovo eyisithupha ngosuku. Thayipha isifo sikashukela 2 sidinga okuncane. Ngazo zombili izinhlobo zezifo, udinga ukunamathela ekudleni okhethekile futhi ungawunaki umsebenzi womzimba.

Ngaphambi kokuqala imijovo udinga ukuyilungiselela. Kulokhu, isiguli kufanele siqale ukukala kaninginingi (kufika izikhathi eziyi-15 ngosuku) okuhlushwa ushukela nsuku zonke. Ukuya esibhedlela ngenxa yalokhu unemali eyanele nesikhathi, ngakho-ke kungcono ukuzisindisa zombili bese uthenge ngokushesha i-glucometer ukwenza inqubo ekhaya.

Iziguli zesifo sikashukela sohlobo 2 zinemijovo ende ye-insulin kuphela ngaphambi kokulala. Ukuqonda ukuthi ngabe injekishini yasekuseni iyadingeka yini, udinga ukuhlaziya inkomba ye-glucose esiswini esingenalutho phakathi nosuku.

Ngakho-ke, sifingqa ukulandelana kwezinyathelo:

1. Izinsuku eziyi-7 silinganisa ukuhlangana koshukela ngaphambi kokulala nangakusasa ngaphambi kokudla.
2. Umphumela wosuku ngalunye ufakwa epuletini (sizohlaziya isifanekiso kamuva).
3. Ngezinsuku ngazinye, bala ushukela wokukhipha ushukela izolo kusihlwa.
4. Khipha izinsuku lapho udle isidlo sakusihlwa ngaphambi kokulala (ngaphansi kwamahora amahlanu).
5. Sichaza ukuqina okulinganiselwe kokuzwela kwethuluzi.
6. Sihlukanisa ukwanda okuncane kakhulu kwe-glucose ngesikhathi sokulala yilesi silinganiso - lokhu kuyithamo lakho lokuqala lomjovo.
7. Singena kumthamo wokuqala ngaphambi kokulala futhi uqiniseke ukuthi usetha i-alamu phakathi kobusuku ukukala ushukela.
8. Uma unokuhlushwa ebusuku ngenhla kwe-3.8, sinciphisa umthamo esiwubeka ngaphambi kokulala. Ungayihlephula ibe yimijovo eminingana bese uyihlaba ingxenye yesibili phakathi kobusuku.
9. Kamuva, umthamo kufanele ulungiswe ukuze kungabikho-hypoglycemia ebusuku noshukela ekuseni esiswini esingenalutho kwakungekho ngaphezu kwe-4.5-0.6 mmol / ilitha yegazi.

Ithebula elinezibalo kufanele libukeke kanjena:

Imvelo ilahlwa ngokuzenzakalelayo ngoba isiguli sidle sekwephuzile. Ukwanda okuncane kakhulu koshukela kwaba ngoLwesihlanu, 4.0. Ukunyuswa okuncane kuthathwe ukuze umthamo ophumile ungabi mkhulu kakhulu kuwe, uzobhekelwa phansi ngamabomu. Ngakho-ke, uphephile ekuthuthukisweni kwe-hypoglycemia.

Isibonelo, awukhiqizi i-hormone yemvelo ye-insulin nhlobo. Ngemuva kwalokho iyunithi izonciphisa ukuhlushwa nge-2 mmol (uma unesisindo esingaphansi kwama-70 kg). Uyacelwa uqaphele ukuthi uma wehlisa isisindo sakho, yilapho umsebenzi we-insulin uqina kakhulu. Kumuntu onesisindo esingama-80 kg, lesi sibalo sizoba cishe ngu-1.7.

Ungabheka inkomba yakho ngamunye ngefomula: Kwisifo sikashukela 1, lesi sibalo sithathwa. Uma unohlobo 2, khona-ke leli nani lezimali lizoba likhulu kakhulu. Ngakho-ke, cabanga ngomthamo osuselwa eqinisweni lokuthi iyunithi leLantus lizonciphisa ukugxila ngo-4,4. Ngokusekelwe kufomula efanayo, ukubala kwakho konke kuyingqayizivele.

Njengoba kwatholakala, ukwanda okuncane kweglucose kwakungu-4 mmol. Isiguli, ngokwesibonelo, sinesisindo esingu-80 kg. Ngemuva kwalokho iyunithi le-insulin lizokwehlisa ushukela ngo-3.52. Kuyavela ukuthi umthamo we-insulin kufanele ube amayunithi ayi-1.13.

Umthamo wasekuseni

Ukuqonda ukuthi udinga lo mjovo nhlobo, okokuqala udinga ukwenqaba ukudla phakathi nosuku. Ukulandelana kwezinyathelo zakho:

• Ungadli kungakapheli amahora ayi-14 ngemuva kokuqeda ukulala, kuphela isidlo sakusihlwa esamukelekile;
• Emini ungaphuza itiye le-herbal, amanzi;
• Khawulela umuthi wakho wesifo sikashukela;
• Linganisa ukuqoqwa koshukela ngokushesha ngemuva kokulala, bese kuthi emva kwehora eli-1, 5, 9, 12 nele-13.

Uma ngesikhathi sokulinganisa unqume ukuthi inani le-glucose egazini lingaphezu kwe-0,6 mmol futhi alizange lehle, khona-ke udinga ukufaka i-insulin ekuseni. Imithamo ibalwa ngendlela efanayo nemithamo yemijovo ngesikhathi sokulala. Ukulungisa umthamo wasekuseni, udinga ukwenza le nqubo futhi, ngakho-ke kunconywa ukunquma umthamo owuthandayo emavikini ahlukene.

Ubuchwepheshe bokwethula kweLantus

Ukufakwa kwanoma yisiphi isidakamizwa esiqukethe i-insulin kunikezwa ngokungazenzisi. Kaningi, iziguli azazi ubuchwepheshe bokulawulwa kwezidakamizwa futhi zenza imijovo engalungile. Ukwenziwa okungafanele kwesibaya sesikhumba kungahlanekezela i-angle yokufakwa kwenaliti. Ngenxa yalokhu, kungangena izicubu zomsipha, khona-ke ukufundwa kokushintshashintsha koshukela ekuhambeni kwegazi kuzobe kungalindeleki.

Kubalulekile futhi ukuthi ungangeni emithanjeni yegazi lapho kukhishwa i-insulin. Ukuze uvikeleke, kungcono ukusebenzisa izinaliti ezithambile nezincanyana ze-insulin ngomjovo.

Ngomjovo we-insulin, izingxenye eziningana zomzimba ziyasetshenziswa:

• Indawo yesisu;
• Ihlombe
• Ithanga langaphambili;
• Amabhokisi.

Kuya ngesayithi lomjovo weLantus, ukumunca kwalo kuhlukahlukene. Umuthi udonswa kangcono uma ugxishwe esiswini; ukumuncipha kancane kwenzeka ngokwawo lapho kufakwa emalangeni nasezintanjeni. Uma uthatha isinqumo sokunikeza umjovo esiswini, lapho-ke udinga ukubuyela enkabeni engaba ngu-5 cm bese ugwaza isiyingi.

Ngezinsuku ezahlukahlukene, udinga ukuguqula indawo yokungena yenaliti. Uyacelwa uqaphele ukuthi uma uthatha ifolda ngokungalungile, uyiqinise ngokuqinile noma ubambe izicubu zemisipha, inaliti izohamba iqinile futhi umjovo uzoba buhlungu.

I-Lantus yezidakamizwa iyanconywa ukuthi isetshenziswe ngalezi zinhlobo zama-syringes:

1. QhafazaSTAR.
2. I-OptiPen Pro1.

Ngaphambi kokuthi uqale ukusebenzisa, qiniseka ukuthi ufunda imiyalo efakwe epeni lesirinji, ngaso sonke isikhathi kufanele unamathele ezincomeni zomenzi.

Ukufakwa kulashwa kanjena:

1. Susa isirinji ecaleni bese ususa isembozo kulo;
2. Susa ukuvikela komuntu kusuka kunaliti bese uyifaka esibayeni sesirinji;
3. Nyakazisa okuqukethwe isirinji bese uxuba;
4. Lapho ulinganisa ngokuchofoza, shayela umthamo wakho okhethwe kuqala ngawodwana;
5. Cindezela inkinobho ku-injector futhi ususe umoya ngenaliti;
6. Endaweni yomzimba lapho kuzojova khona umjovo, yenza isikhumba. Bese ubamba inkinobho imizuzwana eyi-10 ukuze umuthi ungene esikhaleni esingasasebenzi. Bese ukhulula isikhumba, ubambe inalithi eminye imizuzwana engu-5 bese uyikhipha ngokuqinile.

Ngaphambi kokulungisa i-cartridge ibe yisirinji, kungcono ukuyimisa amahora angama-1-3 ngokushisa kwasekamelweni. Ungasebenzisi i-cartridge uma i-precipitate ikhona kusisombululo, ayiveli obala, noma uma uketshezi luwushintshile umbala. Ungakhohlwa ukususa umoya ebhokisini (imiyalelo yachazwa ngenhla). Akunakusebenza ungagcwalisi ama-cartridge, angasebenza.

Ngaphambi kokufaka umjovo, qiniseka ukuthi uhlola kabili igama lomuthi ukuze, ngokungazi, ungazifaki omunye insulin. Iphutha elinjalo lingabulala (imithamo ikhethwe ngezindlela ezihlukile futhi i-hypoglycemia ingenzeka kakhulu).

Uma ungenayo isipedi esifanele sepeni, ungahambisa iLantus ngentambo ejwayelekile ye-insulin. KUBALULEKILE! Uma usebenzisa isirinji ejwayelekile, uqoqe ngokucophelela umuthi, inani lawo ku-insulin kanye nesirinji ejwayelekile yehlukile.

Faka iLantus ngokuya ngale ndlela:

1. Khetha indawo lapho uzongena khona umkhiqizo;
2. Sula isayithi lomjovo nge-antiseptic (uLantus angabhidlizwa ngaphansi kwethonya lama-alcohols, ngakho-ke makunyamalale kungapheli imizuzu engu-5-7 bese uqhubeka nomjovo. Noma ungasebenzisi utshwala obunama-ejenti);
3. Yenza isikhumba (uma usebenzisa inaliti ye-ultrashort, khona-ke awukwazi ukukwenza);
4. Ngaphandle kokukhulula isibaya, faka inaliti nge-angle engu-45 degrees;
5. Kancane kancane ngesandla esiqinile, cindezela ku-piston bese ufaka iLantus;
6. Ngemuva kokufakwa kwe-ejenti, khipha i-crease;
7. Bamba inaliti ngaphansi kwesikhumba sakho imizuzwana emi-5 bese ususa kabukhali.

Uma umjovo weLantus awunawo umphumela owufunayo, hlola kabili ukuphathwa okufanele komuthi. Musa ukujaha ukukhulisa umthamo olawulwa yi-insulin. Uma ulisebenzise kubanda, lizogcotshwa kancane kancane. Uma uphatha i-insulin kahle nangendlela esifike ngesikhathi, izonikeza inkomba ezinzile ye-glycemia.

I-Lantus ngesikhathi sokukhulelwa

Ezinye izifundo ezihlukile zomphumela walesi sidakamizwa kubantu besifazane abakhulelwe azenziwanga. Ngokwezibalo, kubantu abangama-96% abesifazane abekho okuphathelene kabi nokusuka kwesenzo sikaLantus ngesimo sengane kanye nangejwayelekile yesikhathi. Le insulin ayiphazamisi uhlelo lokuzala.

Lesi sidakamizwa sivame ukunikezwa abesifazane abakhulelwe ngochwepheshe. Esimweni esinjalo, isiguli kufanele siqashwe njalo ngudokotela futhi siqaphe njalo ukugcwala koshukela egazini.

Imvamisa, isidingo somuthi siyancipha ngesikhathi sethilitha yokuqala, ngesikhathi 2 no-3, kunalokho, siyanda.

Ngemuva kokuba owesifazane esebelethile, isidingo sokuphathwa kwe-insulin kusuka ngaphandle cishe sincishisiwe ngokuphelele futhi owesifazane angaba ne-hypoglycemia.

Ngesikhathi sokuncelisa, ungasebenzisa i-Lantus, ngenkathi udinga ukubheka njalo umthamo womuthi. Lapho i-insulin glargine ingena emgodini wokugaya ukudla, iqala ukudiliza ibe ngama-molecule e-amino acid. Kulesi simo, akubangeli ukulimala enganeni, ophathiswe i-maloca yesifuba.

Ngubani okungafanele asebenzise uLantus?

Lesi sidakamizwa esiqukethe i-insulin sikhonjelwe ngokuphelele emikhakheni enjalo yeziguli:

• Labo abanokungabekezeleli ngakunye kwe-insulin glaragin noma ezinye izinto eziyingxenye yomuthi;
• Abantu abanoma yiluphi uhlobo lwe-hypoglycemia;
• Izingane ezingaphansi kweminyaka engu-6.

Leli khambi alisizi nge-ketoacidosis yesifo sikashukela. Ngokunakekelwa okukhethekile, udinga ukusebenzisa iLantus ngoba inenkinga yokunciphiswa kwemithambo ye-cerebral and coronary, i-autonomic neuropathy, ukuphazamiseka kwengqondo, isifo sikashukela esivele isikhathi eside, i-retinopathy ekhulayo, kanye nalabo abajwayele ukuhlaselwa yi-hypoglycemia.

Kwezinye iziguli, izimpawu zesimo se-hypoglycemic zingase zingenzeki.

Ukuqashwa kukaDokotela kudingwa abantu asebekhulile nabantu abaguqula i-insulin yezilwane iye kubantu, abantu abane-hypersensitivity to insulin, iziguli ezinengcindezi engapheli nokuzivocavoca ngokomzimba, ukuthatha eminye imishanguzo, kanye nalabo abanezifo ezihlangabezana nazo.

Ngesikhathi sokusetshenziswa kweLantus, isiguli ngasinye kufanele sidle ngokwejwayelekile (ngesifo sikashukela, kuboniswa ukudla okune-carb ongaphansi) bese sizama ukuphuza utshwala obuncane ngangokunokwenzeka.

Uyacelwa uqaphele ukuthi iLantus ingathinta kabi ikhono lokugxila nokugxila. Kungavusa ukuthuthukiswa kwe-hyper- ne-hypoglycemia, ngenxa yokuthi umbono uyancipha futhi uqala ukudideka. Ngakho-ke, abantu abaphathwa ngale mishanguzo neminye imitshanguzo ngesikhathi sokwelashwa bahlukunyezwa ukushayela imoto noma ukwenza umsebenzi oyingozi.

Izindlela ezifanayo

Emakethe yamakhemikhali, kunezindawo eziningi ezinama-insulin aqukethe izithako, isithako esiyisisekelo esisebenzayo okuyi-insulin glargine:

• Isixazululo somjovo we-Aylar - sibiza cishe ama-ruble angama-3,000;
• Izincazelo zeLantus nezisombululo zeSolostar - ama-ruble angama-3000;
• I-Tozheo Solostar - kusuka kuma-ruble ayi-1000 kuye kwangama-2500.

Ezinye izidakamizwa ezifanayo zesenzo:

Uyacelwa ukuthi wazi ukuthi ezinye zalezi zidakamizwa zinemikhawulo ethile nemiphumela emibi. Zingahle ziphikiswe kuwe futhi ziziphathe ngokungacabangi lapho zisetshenziswa. Ngakho-ke, ngaphambi kokushintsha usuka eLantus uye kolunye uhlobo lwe-insulin, thinta uchwepheshe wakho.

Ukubuyekezwa kweLantus

Isiphetho

Ngamapharamitha we-pharmacological kanye nawokomzimba, iLantus ingenye yezidakamizwa ezinhle kakhulu zokwelapha isifo sikashukela. Ifana kakhulu ne-insulin yemvelo futhi ayinamphumela omubi emzimbeni. Iphuzu elibalulekile kuphela lapho usebenzisa leli thuluzi (kanye nokunye ukufakwa) ukugcinwa kwemithamo nobuchwepheshe bokusebenzisa umuthi.