Ukuhlaziywa kwe-C-peptides ku-mellitus yesifo sikashukela: izinkambiso, izimbangela zokwanda nokuncipha

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Ku-mellitus yesifo sikashukela, isiguli kufanele siqaphe isimo sayo, sithathe izivivinyo ezidingekayo.

Enye yezinkomba eziphambili ileveli kashukela egazini, enganqunywa ngaphandle kokuhlolwa kwelebhu usebenzisa i-glucometer. Akubalulekanga kangako ukuhlaziywa kwe-C-peptides kushukela.

Ikuvumela ukuthi unqume inani le-insulin ekhishwa ngumzimba. Kucatshangelwa ukuthi yikuphi lapho kudingeka kwenziwe futhi kanjani, zisho ukuthini izinkomba ezithile, okufundwe kulokhu okuqukethwe.

Izinkomba zokuhlaziywa

Ukubaluleka kokuhlaziywa kwe-C-peptides kubhekwa njengokuchazwa kwezinga lokuhlanganiswa kwe-insulin. Lokhu kuyingxenye ye-proinsulin eyenziwe emzimbeni womuntu. Ngokuhlushwa ushukela okujwayelekile egazini, kungenzeka ukuthi lolu hlaziyo alukho.

Ngezinkomba ezengeziwe, izifundo ezengeziwe ziyadingeka ezingakwazi ukuxazulula lezi zinkinga ezilandelayo:

  • nquma izinga le-insulin egazini;
  • qonda izimbangela ze-hypoglycemia;
  • khomba izindawo ezinempilo zama-pancreas uma kwenzeka kwenziwa ukuhlinzwa;
  • nquma umsebenzi wama-antibodies ngokumelene ne-insulin;
  • hlola umsebenzi we-beta cell ngohlobo 1 noma uthayiphe ushukela 2.

Lolu lwazi luzokuvumela ukuthi unikeze ukwelashwa okusebenzayo.

Ngakho-ke, izinkomba zokuhlaziywa kwe-C-peptides zingokulandelayo:

  • ukuzimisela kohlobo lwesifo;
  • ukukhethwa kokwelashwa kwalesi sifo;
  • ukuxilongwa kwe-hypoglycemia;
  • isidingo sokubheka isimo sentsha eyeqile ngokweqile;
  • ukuhlolwa kwesimo se-pancreas lapho senqaba ukwelashwa kwe-insulin;
  • nge-pathology yesibindi, ukukhiqizwa kwe-insulin kumele kulawulwe;
  • nge-polycystic ovary syndrome kwabesifazane;
  • ngemuva kokususwa kwama-pancreas ukulawula isimo.

Ukulungiselela ukunikela ngegazi

Njengoba i-insulin ikhiqizwa ama-pancreas, khona-ke ucwaningo luyadingeka ukuze kuhlaziwe ukusebenza kwalo. Lokhu kusho ukuthi ngaphambi kwenqubo, izindlela zokudla kumele zilandelwe ezinomthelela ekusebenzeni okujwayelekile komzimba.

Ukulungiselela ukunikela ngegazi ukuze lihlaziywe kubandakanya imisebenzi elandelayo:

  • ungadli ukudla okungenani amahora angama-8 ngaphambi kwenqubo;
  • khipha iziphuzo ezimnandi nezikhishwa ngamakhabhoni, uphuze kuphela amanzi ngaphandle koshukela;
  • ungasebenzisi izidakamizwa uma kungenzeka;
  • khipha utshwala ekudleni;
  • ungabhemi okungenani amahora ama-3 ngaphambi kwenqubo;
  • Gwema ukucindezelwa okungokomzwelo nangokomzimba.
Ngenxa yesidingo sekhefu elide ekusebenzeni kokudla ngaphambi kokuhlaziywa, kunconywa ukuthi kwenziwe inqubo ekuseni. Kubalulekile futhi ukubika ukusetshenziswa kwezidakamizwa, uma ngabe lokhu bekuphoqelekile.

C-peptides kushukela

Ungathola imiphumela yokuhlaziywa kungakapheli amahora amathathu. Inqubo yokuqoqa impahla ayihlukile kunamasampula egazi ajwayelekile. I-vein ihlotshwa ngenaliti bese okuqoqiwe kuqoqwe ku-tube eyinyumba.

Njengomphumela, izinkomba zitholakala ukuthi okujwayelekile imingcele kusuka ku-0.78 kuya ku-1.89 mcg / l.

Lo mphumela ubalulekile lapho wenza isifundo sesisu esingenalutho. Ngaphezu kwalokho, ukuthola isithombe esiphelele sesimo, kunconyelwa ukwenza kanyekanye ukuhlaziya okwenziwe.

Ngezinga elikhulayo, kubalulekile ukuqonda ukuthi kubangelwa ukukhiqizwa kwe-hormone ngamanyikwe noma ngenxa yokufakwa komjovo. Ukuze wenze lokhu, thola isilinganiso se-insulin ne-C-peptide.

Okujwayelekile inani eliseduze nobunye. Uma inani lincane, khona-ke lokhu kukhombisa ukukhiqizwa okukhuphukile kwe-hormone emzimbeni. Uma inkomba inkulu kuneyodwa, khona-ke i-insulin ilethwa ngesikhathi somjovo.

Uhlobo olu-1

Ama-diabetesics ohlobo lokuqala abonakala ngokuqukethwe okuphansi kwe-insulin emzimbeni. Lokhu kungenxa yokubhujiswa kwezicubu ze-pancreatic.

Azidingeki nje ukwehlisa amazinga kashukela kanye nokugaya, kodwa futhi nokukhuthaza ukwenziwa kwe-insulin.

Ukubhujiswa okubalulekile kwabo kuholela ekunciphiseni ngokushesha kwehormone nokubonakaliswa kwezimpawu zesifo.

Izinhlobo ezi-2

Uhlobo 2 sikashukela, kunalokho, lubonakala ngokwanda kwamazinga e-insulin. Lokhu kungenzeka ngenxa yezizathu eziningi, njengoku:

  • isakhi sofuzo;
  • ukuvivinya umzimba okukhulu
  • ukucindezela okukhulu;
  • ukukhuluphala
  • izifo ezithathelwanayo noma ezingamagciwane;
  • ukwephulwa kokusebenza komzimba.

Lezi zinto ziholela eqinisweni lokuthi, yize kukhiqizwa i-hormone ngamanani anele, ayihambelani neglucose eqoqiwe.

Akunakungena kumaseli ngenxa yokuthi ama-receptors ayeka ukusebenza. Ngenxa yalokhu, i-insulin ikhiqizwa nangokwengeziwe, okuholela kuzimpawu ezingathandeki.

Ushukela ujwayelekile, futhi i-C-peptide iyaphakanyiswa: kusho ukuthini?

Ukwanda kwe-C peptide kungabonisa ukuba khona kwale mibandela elandelayo:

  • uhlobo 2 sikashukela;
  • ukuthuthukiswa kwe-insulinoma;
  • ukwehluleka kwezinso;
  • ukufakelwa kwamaseli we-beta noma ama-pancreas wonke;
  • isisindo ngokweqile;
  • kwabesifazane, ukusetshenziswa isikhathi eside kwe-estrogen;
  • ukuphathwa kwangaphakathi kwezidakamizwa ezinciphisa ushukela;
  • ukuthatha i-glucocorticoids isikhathi eside.

Ukudlula kokugcotshwa kwama-peptides kukhombisa i-hyperinsulinemia, ebonakala ezigabeni zokuqala zesifo sikashukela, imvamisa yohlobo 2.

Kodwa-ke, kwenzeka ukuthi ngezinga eliphakeme lama-peptides, ushukela uhlala uvamile. Kulesi simo, sikhuluma ngentuthuko yesifo se-insulin noma i-prediabetes, okuyindlela esezingeni eliphakathi lalesi sifo.

Akunakwenzeka ukujova i-insulin uma i-C-peptide iphakanyisiwe. Njengokwelashwa, ukudla okune-carb ephansi nokuzivocavoca kufanelekile.

Uma izinga liphansi, kusho ukuthini?

Uma ngemuva kokuhlaziywa kwehla ama-peptides, lapho-ke lokhu kukhombisa imibandela elandelayo:

  • ukuhlinzwa kwe-pancreatic;
  • ukwethulwa kwe-insulin, okuholela ku-hypoglycemia yokufakelwa;
  • uhlobo lwesifo sikashukela esincike ku-insulin.

Ukwehlisa i-hormone kungenzeka ngokudakwa ngokweqile futhi ezimweni ezinzima zokucindezela.

Ngokuncipha okukhulu kwezinga lama-peptides futhi ngasikhathi sinye okwejwayelekile umbandela wokuhlushwa ushukela, amathuba ezinkinga aphakeme:

  • ukulimala kwemizwa nemithambo yegazi yemikhawulo engezansi;
  • izilonda zesikhumba;
  • ukulimala kwamehlo kwesifo sikashukela;
  • ukulimala izinso nesibindi.

Ukusetshenziswa kwama-peptides kanye nama-bioregulators ekwelapheni isifo sikashukela

Ukwelashwa kwesifo sikashukela kuhloswe ikakhulukazi ukugcina isimo esijwayelekile kanye nokudambisa izimpawu zesifo.

Ukuthuthukisa ikhwalithi yempilo, ama-peptide bioregulators anqunywa kanye nezidakamizwa zendabuko. Le ndlela isiza ekwenzeni ngcono ukusebenza kwamanyikwe.

Ama-peptides ayizingxenye zesakhiwo samaprotheni ahlanganisa ukwakheka kwawo. Ngenxa yalokhu okwakhiwa, umthethonqubo wezinqubo ze-biochemical kumaseli uyenziwa.

Lesi yisisekelo sokulungiswa kwezicubu ngokuvamile, ngenxa yokuthi ukusebenza kwesitho esifanelekile kuyaqinisekiswa. Ama-peptide bioregulators anesibopho sokubandakanyeka kwezinqubo ze-metabolic emangqamuzaneni ama-pancreas, anikela ekwenziweni kwe-insulin.

Isidakamizwa Svetinorm

Ngokuhamba kwesikhathi, umzimba uqobo uqala ukubhekana nemisebenzi yawo futhi nesidingo sokuthi imijovo iyeke ukusebenza. Namuhla emakethe kunokunikezwa okucatshangelwa kwezidakamizwa ngokususelwa kuma-peptides. Lokhu kufaka iSuperfort, Svetinorm, Wertfort, Endoluten, Cetroluten, Visoluten.

Amavidiyo ahlobene

Mayelana nencazelo ye-C-peptide yesifo sikashukela kuvidiyo:

Ngakho-ke, lapho kunezimpawu zesifo sikashukela i-mellitus, ukuhlaziya kwesinye isikhathi akwenziwa hhayi ngoshukela wegazi, kepha futhi nokuxineka kwe-C-peptides.

Kuyasiza ukunquma uhlobo lwe-pathology, isimo se-pancreas ukunquma ukwelashwa okuqhubekayo. Kodwa-ke, ucwaningo selukhombisile ukuthi ukwelapha lesi sifo ngemithi esekwe peptide kuthuthukisa ukusebenza kwesitho nesimo sesiguli.

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