Ku-mellitus yesifo sikashukela, kubalulekile ukuba ulondoloze umzimba obuthakathaka, wehlise umthwalo kuma-pancreas, isibindi, emithanjeni yegazi.
I-Berlition yezidakamizwa ikhombisa umphumela we-antioxidant, i-normalization ye-lipid ne-carbohydrate metabolism. Ikhambi elisebenzayo lehlisa ukubonakaliswa kwe-neuropathy yesifo sikashukela.
Imiphumela emibi yenzeka kakhulu lapho usebenzisa i-Berlition yezidakamizwa. Imiyalo yokusebenzisa iyadingeka ukuze ufunde.
Ukwakheka, isenzo
Umenzi unikeza i-Berlition yezidakamizwa ngamafomu amathathu womthamo:- amaphilisi asuselwa ku-alpha-lipoic (thioctic) acid 300 no-600 mg;
- gxila, ngesisekelo lapho odokotela belungiselela khona isisombululo sokungenelela;
- amaphilisi athambile aqukethe i-alpha lipoic acid - 300 mg. Umenzi uphinde anikeze uhlobo lomlomo wesidakamizwa ngokuxineka okuphezulu - i-600 mg yento esebenzayo.
Izinhlobo zokuvezwa emzimbeni we-α-lipoic acid:
- kuvuselela ukuqothulwa kwe-cholesterol eyingozi;
- ijwayele isibindi;
- ubamba iqhaza ku-fat and carbohydrate metabolism;
- ikhombisa umphumela we-hypoglycemic;
- kunciphisa i-lipids ne-cholesterol;
- ibopha ama-radicals wamahhala, ikhombisa umphumela we-antioxidant;
- kunciphisa izinga lokumelana ne-insulin;
- kwandisa ukugcwala kwe-glycogen kumaseli wesibindi.
Indlela yokusebenza yesidakamizwa
I-Alpha lipoic acid yinto efana ne-Vitamin.
Ingxenye esebenzayo ibandakanyeka ku-decarboxylation ye-α-keto acid, isebenza njenge-coenzyme.
Into esebenzayo ivikela amaseli emiphumeleni emibi yama-radicals mahhala.
Ukuphathwa kwezifundo ze-Berlition kanye ne-infravenous infusion kukhuthaza ukukhiqizwa kwe-glutathione, kusebenze ukuhamba kwegazi okungapheli. Ukusetshenziswa kwesidakamizwa ngokuya ngemiyalo kunciphisa ubungozi bokuqongelwa ushukela emikhunjini. Umphumela uba ukuma okujwayelekile komthethonqubo wezinzwa ku-polyneuropathy yesifo sikashukela, nomsebenzi wamaseli wesibindi.
Ukuqalwa kwe-bioavailability kwe-thioctic acid ngemuva kokuphathwa ngomlomo kuze kufike ku-20%, ukuvezwa kwesiqongo segazi kuphawulwe ngemuva kwemizuzu engama-30. Ama-Metabolites adalulwa yizinso, i-half-life isifushane - ngaphansi kwesigamu sehora.
Izinkomba
Kusetshenziswa umjovo we-Berlition kanye namathebulethi ekwakheni i-neuropathy yesifo sikashukela kanye ne-paresthesia ezigulini ezine-endocrine pathology engapheli. I-antioxidant esekwe ku-α-lipoic acid imiselwe ukulimala kwesibindi okunzima, kufaka phakathi ngenxa yotshwala.
Umthamo kanye ne-overdose
Udokotela ubeka isilinganiso esisodwa kanye nesilinganiso sansuku zonke, ebheka izincomo ezichazwe kwimiyalo. Ezimweni ezimbi kakhulu ze-pathologies esiteji sokuqala (kusuka ezinsukwini eziyi-14 kuye kwezingama-30), kusetshenziswa amaphilisi noma amaphilisi, kulandelwa ukumiliselwa kwethambo. Isikhathi sokwelashwa sinqunywa yi-endocrinologist noma i-gastroenterologist, sinaka isimo.
Ukuphathwa kwabazali kwenziwa ngumsebenzi wezempilo. Kubalulekile ukulawula isimo: ngezimpawu zomzimba ngamunye, ukushaqeka kwe-anaphylactic kungenzeka. Ukuvela kwe-edema, ubuthakathaka, ukulunywa isikhumba, isicanucanu kuyizimpawu, ngentuthuko yazo eyeka inqubo. Lapho impendulo yokuzivikela komzimba ithuthukiswa, isiguli sithola i-antihistamine esebenza ngokushesha, ngokwesibonelo, uSuprastin noma iTavegil.
Isigaxa se-Berlition
Umthamo:
- Isixazululo sokufakwa. Ukugxila okuvela ku-ampoule kuhlanjululwe ngento eyodwa kuphela - i-sodium chloride 9%. Ngaphambi kokuqala kokufakwa kwe-intravenous, isitsha esinesixazululo sivalekile nge-aluminium foil: kubalulekile ukukhipha ukufinyelela ukukhanya. Izinga lokumisela elilungile ukwethula u-250 ml wetshezi engxenyeni yehora. Ngokubonakaliswa okumisiwe kwe-polyneuropathy, abanesifo sikashukela bathola kusuka ku-300 kuye ku-600 mg wento esebenzayo.
- Izibhebhe ze-Berlition namaphilisi athambile. I-antioxidant yokuqeda ukubonakaliswa kwe-neuropathy itholwa esiswini esingenalutho, isigamu sehora ngaphambi kokudla kwasekuseni ngomthamo omkhulu we-liquid. Amakhandlela namathebulethi kumele aphuthwe aphelele. Umthamo we-Optimum: 1 i-capsule Berlition ama-600 noma ama-2 amaphilisi we-300 mg noma ama-2 amaphilisi. Inani lansuku zonke kumele litholakale ngasikhathi sinye. Ngama-pathologies wesibindi, umthamo uphakeme - ukusuka ku-600 kuye ku-1200 mg wento esebenzayo kungakapheli amahora angama-24.
Izimpawu nemiphumela yokudakwa ngokweqile:
- isicanucanu
- ikhanda elinzima;
- ukwephulwa kokuphendula kwe-psychomotor;
- ukwazi okungaphelele;
- ukuqunjelwa.
Ngokudakwa kakhulu, kuba:
- i-lactic acidosis;
- ukungasebenzi komongo;
- i-hypoglycemic coma;
- ukwethuka okujwayelekile;
- ukwehluleka kwezitho eziningi;
- isimo sokushaqeka;
- ushintsho kuzinga lokuhlangana kwegazi.
Ukuthola i-10 g ye-thioctic acid kungaholela ekutheni udakwe kakhulu, uma ungekho ekwelashweni, uvuse umphumela obulalayo. Lapho isakhi esisebenzayo somuthi i-Berlition sihlanganiswa nezidakamizwa eziqukethe utshwala, izimpawu zobuthi ziqhakaza.
Ukusebenzelana kwezidakamizwa
Ama-nuances abalulekile:
- ohlotsheni lwesifo sikashukela sokuqala nesesibili, umthamo wama-hypoglycemic agents kufanele ulungiswe: i-α-lipoic acid ikwehlisa ngokweqile i-glucose egazini;
- ungaphuzi utshwala namagama asuselwa ku-ethyl alcohol;
- lapho ihlanganiswa ne-iron, i-magnesium, i-calcium, i-α-lipoic acid yakha izakhi eziyinkimbinkimbi. Ukuze ungafaki ukusebenzisana kwezidakamizwa ngokuya ngezinto ezilandelwayo ezilandelwayo ezine-amaphilisi noma isixazululo se-Berlition, qiniseka ukubekezelela isikhathi sokuphumula samahora ayi-6 kuye kwayi-8;
- I-Cisplatin yezidakamizwa ayisebenzi kangako uma ihlanganiswa ne-antioxidant esekelwe ku-thioctic acid.
Imiphumela emibi nokuphikisana
Iningi labantu abathola ukwelashwa kwezidakamizwa libonisa ukubekezelela okuhle kumathebulethi kanye ne-infusions nge-α-lipoic acid. I-Berlition yezidakamizwa, ngokuzwa komuntu ngamunye komzimba, ingavusa imiphumela emibi.
Amaphesenti amancane ahlangabezana nokuboniswa okulandelayo:
- eczema
- ukuqhuma kwesikhumba, ubomvu be-epidermis;
- isifo sohudo, isicaba, isicanucanu, ushintsho ekunambithekeni, ekuhlanzeni;
- umkhuhlane nokubomvu entanyeni nobuso, i-tachycardia, ukuqina kwesifuba. Ukusabela okungalungile kwenzeka ngokwephula imithetho yokuphathwa kwe-intravenous;
- i-hypoglycemia;
- Isiyezi
- ukujuluka ngokweqile;
- ukuthuthukiswa kwe-thrombocytopenia;
- kukhona ubuhlungu endaweni yekhanda;
- ubunzima bokuphefumula
- ukugoba, ukusindeka ekhanda ngokuphathwa ngokushesha kwekhambi.
Imikhawulo yokusetshenziswa kwomuthi i-Berlition:
- ukukhulelwa
- iminyaka efinyelela eminyakeni eyi-18;
- ukungabekezelelani kwe-fructose;
- inkathi yokuhlanza;
- hypersensitivity esenzweni se-α-lipoic acid.
Izindleko
Umenzi wenkampani iBerlin-Chemie AG (Germany).Amanani aphakathi:
- I-Berlition 600 ukugxila, ama-ampoules ama-5 - ama-ruble angama-800;
- I-Berlition 300 ukugxila, ukupakisha No. 5 - 720 ruble;
- amaphilisi, ama-300 mg we-thioctic acid, inani - izingcezu ezingama-30, zibiza - ama-ruble ayi-750.
Gcina ama-ampoules endaweni emnyama, hhayi emanzi.
Ngemuva kokulungiselela, sebenzisa ikhambi ngemuva kokuphakama kwamahora ayisithupha. Ukulondolozwa kwezokwelapha, ukulungiswa komlomo kufanele futhi kugcinwe kwiphakeji evaliwe ngaphandle kokuthola ukukhanya. Umbuso wokushisa olungile usukela ku-+15 kuya ku- +30 degrees.
Ama-Analog
Kumakhemisi, ungathenga isisombululo sokuphatha kwabazali negama lokuphathwa ngomlomo:
- I-Tiolepta.
- I-Tiogamm.
- Lipothioxone.
- I-Oktolipen.
- Espa Lipon.
Ama-Analogs we-Berlition asuselwa ku-thioctic acid nawo ayatholakala kadokotela.
Lapho ukhetha obambele, kubalulekile ukubheka uhlu lwemithi etholwa yisifo sikashukela noma umuntu onama-pathologies wesibindi.
Ukusetshenziswa kwazo zonke izinhlobo zemithamo ye-Berlition yezidakamizwa kunciphisa ukubonakaliswa kwe-polyneuropathy yesifo sikashukela. Umuthi osebenzayo osuselwa ku-α-lipoic acid unciphisa ukugcwala koshukela egazini, unomphumela omuhle ekusebenzeni kwe-cholesterol nesibindi.
