I-Gliformin isetshenziswa kakhulu ekwelapheni isifo sikashukela ngenxa yomphumela wayo we-hypoglycemic, ehambisana nokwehla kwe-glucose emathunjini nokwenyuka kwezinga layo lokudla ngokusetshenziswa kwezicubu zomzimba eziningi.
Khipha amafomu nento esebenzayo
I-Gliformin, etholakala ngentengiso, ivezwa ngesimo sezinhlobo ezimbili ezahlukene zamathebulethi:
- Amaphilisi we-Flat aqukethe i-0.5 g yesithako esisebenzayo futhi ayatholakala emabhulashini obujwayelekile;
- Amaphilisi aqukethe i-0.85 noma i-1 g yesithako esisebenzayo futhi atholakala ezitsheni zepulasitiki ezingama-60.
Isithako esikhulu esisebenzayo eGliformin yi-metformin hydrochloride.
Into esebenzayo yeGliformin yi-metformin
Indlela yokusebenza
Ukusetshenziswa kwe-glyformin ku-mellitus yesifo sikashukela kuboniswa kuphela njengoba kuchazwe udokotela oholayo, ngoba inkambo yalesi sifo kufanele ilawulwe ngokuqinile ukuvimbela ukuthuthukiswa kwezinkinga zayo nemiphumela emibi yokwelashwa.
IGliformin inethonya eliyinkimbinkimbi le-hypoglycemic emzimbeni:
- kunciphisa ukwakheka kwama-molecule eglucose kumaseli wesibindi;
- kwenyusa ukungena kwe-glucose ngamanye izicubu, okunciphisa ukugxila kwayo egazini;
- kuphazamisa ukumuncwa kwe-glucose kusuka ku-lumen yamathumbu.
I-Gliformin, noma isithako sayo esisebenzayo, iMetformin hydrochloride, lapho igxotshwa imunwa ngokushesha amaseli wamathumbu. Iqoqo eliphezulu lomuthi osegazini liyabonakala ngemuva kwamahora ama-2 ngemuva kokuwuthatha.
I-Gliformin iyisidakamizwa esisebenzayo ekwelapheni isifo sikashukela sohlobo 2
Ukusetshenziswa kwe-Gliformin
Ukusetshenziswa kwesidakamizwa kukhonjisiwe eqenjini elilandelayo leziguli:
- Iziguli ezinesifo sikashukela sohlobo lwe-II mellitus, lapho ukulungiswa kokudla nokwelashwa nge-sulfonylurea derivatives kwakungasebenzi.
- Iziguli ezinesifo sikashukela sohlobo lwe-I. Kulokhu, i-glyformin isetshenziswa kanyekanye ne-insulin therapy.
Ukusetshenziswa kwezidakamizwa
IGlatiniin iyanconywa ukuthi isetshenziswe nokudla, noma ngemuva kokukuthatha, ukuphuza amaphilisi anamanzi amaningi acacile.
Emavikini amabili okuqala okwelashwa (isigaba sokuqala sokwelashwa), umthamo wansuku zonke osetshenziswayo kufanele ungabi ngaphezu kwe-1 g. Umthamo wanda kancane kancane, kepha imikhawulo iyabhekwa - umthamo wokulungisa umuthi kufanele ungabi ngaphezu kwe-2 g ngosuku, uhlukaniswe ngemithamo emibili noma emithathu ngosuku.
Uma isiguli sineminyaka engaphezu kwengu-60 ubudala, khona-ke umthamo omkhulu womuthi awudluli i-1 g ngosuku.
I-Gliformin isebenza ngempumelelo ikakhulukazi kwiziguli ezinenhlanganisela yohlobo 2 sikashukela nokukhuluphala.
Contraindication
Ukusetshenziswa kwe-Gliformin kufakwe kuphikisiwe phambi kwe-pathologies elandelayo esigulini:
- izimo ze-hypoglycemic, n. isifo sikashukela;
- i-ketoacidosis ehambisana ne-hypoglycemia;
- ukuzwela kuzakhi zomuthi;
- ukukhulelwa nokuncelisa ibele.
Lapho kukhona izifo ezibangelwa ukugula kanye nezifo ezithathelanayo esigabeni esibuhlungu, kudingeka kunikezwe ukunakwa komthamo odingekayo.
Imiphumela emibi
I-Gliformin nokusetshenziswa isikhathi eside ingaholela ekwakhiweni kwemiphumela emibi elandelayo:
- izimo ze-hypoglycemic ezihambisana nomphumela oqondile wesidakamizwa;
- ukuthuthukiswa kwe-anemia;
- ukungahambi kahle komzimba ngokungabekezeleli izingxenye zomuthi;
- Izimpawu ze-dyspeptic (isicanucanu, ukuhlanza, ukuphazamiseka kwesitulo) kanye nesifiso sokudla esinciphile.
Ezimweni zokuvela kwale miphumela emibi, kufanele uthintane nodokotela wakho ukuze ulungise umthamo womuthi.
Uma lezo zimpawu zenzeka ngenkathi uthatha i-Gliformin, khona-ke kungenzeka ukuthi umuthi ubangela ukuba ukhule i-hypoglycemia
Ukubuyekezwa mayelana neGliformin
Impendulo evela kodokotela iyakhanya. Umuthi usetshenziswa ngenkuthalo ekwelashweni okuyinkimbinkimbi ekwelapheni isifo sikashukela semihlobo yokuqala neyesibili. IGliformin isebenza ngempumelelo ekwelapheni lezi zifo.
Iziguli ezimweni eziningi ziyaneliswa ngokuthatha umuthi. Imiyalo yomuthi ichazwe kakhulu, okuvumela isiguli ngasinye ukuthi siqhubeke siqonde izindlela zesenzo kanye nezici zokuthatha i-Gliformin. Kodwa-ke, ngenxa yokuphatha kabi umuthi, imiphumela emibi ingahle ivele.
Izithonjana zikaGliformin
Ama-analogues aphambili eGliformin yimithi equkethe into efanayo esebenzayo - Metformin hydrochloride. Le mishanguzo ifaka iMetformin, iGlucoran, iBagomet, iMetospanin nezinye.
Ekuphetheni, kubalulekile ukuqaphela ukuthi inhloso yomuthi nokuzimisela komthamo odingekayo kufanele kube ngaphansi kokuqondisa kukadokotela ozobakhona. Ngaphandle kwalokho, ukuthuthukiswa kwemiphumela emibi ekwelashweni nasekuthuthukisweni kwezinkinga zesifo sikashukela kungenzeka.
